Mycobacterium tuberculosis supports protein tyrosine phosphorylation

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 25, 2014, Pages 9265-9270

  Kusebauch, Ulrike ^a   Ortega, Corrie ^b,c   Ollodart, Anja ^b   Rogers, Richard S ^a   Sherman, David R ^b,c   Moritz, Robert L ^a   Grundner, Christoph ^b,c  

^a INSTITUTE FOR SYSTEMS BIOLOGY   (United States)

^b SEATTLE BIOMEDICAL RESEARCH INSTITUTE   (United States)

^c UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; MYCOBACTERIUM TUBERCULOSIS PROTEIN; PHOSPHOTYROSINE; PROTEIN SERINE THREONINE KINASE; UNCLASSIFIED DRUG;

ARTICLE; BACTERIAL GROWTH; ENZYME ACTIVITY; ENZYME SPECIFICITY; IN VITRO STUDY; MASS SPECTROMETRY; MUTATION; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING;

BACTERIAL PROTEINS; HUMANS; MUTATION; MYCOBACTERIUM TUBERCULOSIS; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; SIGNAL TRANSDUCTION;

EID: 84903477543     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1323894111     Document Type: Article

References (47)

1. Pérez J, Castañeda-García A, Jenke-Kodama H, Müller R, Muñoz-Dorado J (2008) Eukaryotic-like protein kinases in the prokaryotes and the myxobacterial kinome. Proc Natl Acad Sci USA 105(41):15950-15955.
2. Fernandez P, et al. (2006) The Ser/Thr protein kinase PknB is essential for sustaining mycobacterial growth. J Bacteriol 188(22):7778-7784. (Pubitemid 44764514)
3. Wehenkel A, et al. (2008) Mycobacterial Ser/Thr protein kinases and phosphatases: Physiological roles and therapeutic potential. Biochim Biophys Acta 1784(1):193-202.
4. Bender MH, Cartee RT, Yother J (2003) Positive correlation between tyrosine phosphorylation of CpsD and capsular polysaccharide production in Streptococcus pneumoniae. J Bacteriol 185(20):6057-6066. (Pubitemid 37248458)
5. Ilan O, et al. (1999) Protein tyrosine kinases in bacterial pathogens are associated with virulence and production of exopolysaccharide. EMBO J 18(12):3241-3248. (Pubitemid 29276571)
6. Vincent C, et al. (2000) Relationship between exopolysaccharide production and protein-tyrosine phosphorylation in gram-negative bacteria. J Mol Biol 304(3):311-321.
7. Wugeditsch T, et al. (2001) Phosphorylation of Wzc, a tyrosine autokinase, is essential for assembly of group 1 capsular polysaccharides in Escherichia coli. J Biol Chem 276(4):2361-2371.
8. Chow K, Ng D, Stokes R, Johnson P (1994) Protein tyrosine phosphorylation in Mycobacterium tuberculosis. FEMS Microbiol Lett 124(2):203-207. (Pubitemid 124012917)
9. Bach H, Wong D, Av-Gay Y (2009) Mycobacterium tuberculosis PtkA is a novel protein tyrosine kinase whose substrate is PtpA. Biochem J 420(2):155-160.
10. Kelkar DS, et al. (2011) Proteogenomic analysis of Mycobacterium tuberculosis by high resolution mass spectrometry. Mol Cell Proteomics 10(12):M111.011627.
11. Prisic S, et al. (2010) Extensive phosphorylation with overlapping specificity by Mycobacterium tuberculosis serine/threonine protein kinases. Proc Natl Acad Sci USA 107(16):7521-7526.
12. Gnad F, Gunawardena J, Mann M (2011) PHOSIDA 2011: The posttranslational modification database. Nucleic Acids Res 39(Database issue):D253-D260.
13. Lee DC, Jia Z (2009) Emerging structural insights into bacterial tyrosine kinases. Trends Biochem Sci 34(7):351-357.
14. Koul A, et al. (2000) Cloning and characterization of secretory tyrosine phosphatases of Mycobacterium tuberculosis. J Bacteriol 182(19):5425-5432.
15. Wong D, Chao JD, Av-Gay Y (2013) Mycobacterium tuberculosis-secreted phosphatases: From pathogenesis to targets for TB drug development. Trends Microbiol 21(2):100-109.
16. Ballif BA, Villén J, Beausoleil SA, Schwartz D, Gygi SP (2004) Phosphoproteomic analysis of the developing mouse brain. Mol Cell Proteomics 3(11):1093-1101. (Pubitemid 40012102)
17. Olsen JV, et al. (2006) Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. Cell 127(3):635-648. (Pubitemid 44647421)
18. Ge R, Shan W (2011) Bacterial phosphoproteomic analysis reveals the correlation between protein phosphorylation and bacterial pathogenicity. Genomics Proteomics Bioinformatics 9(4-5):119-127.
19. Macek B, et al. (2008) Phosphoproteome analysis of E. coli reveals evolutionary conservation of bacterial Ser/Thr/Tyr phosphorylation. Mol Cell Proteomics 7(2):299-307. (Pubitemid 351298444)
20. Hansen AM, et al. (2013) The Escherichia coli phosphotyrosine proteome relates to core pathways and virulence. PLoS Pathog 9(6):e1003403.
21. Jadeau F, et al. (2012) BYKdb: The Bacterial protein tYrosine Kinase database. Nucleic Acids Res 40(Database issue):D321-D324.
22. Ansong C, et al. (2013) Identification of widespread adenosine nucleotide binding in Mycobacterium tuberculosis. Chem Biol 20(1):123-133.
23. Arora G, et al. (2012) Unveiling the novel dual specificity protein kinases in Bacillus anthracis: Identification of the first prokaryotic dual specificity tyrosine phosphorylation-regulated kinase (DYRK)-like kinase. J Biol Chem 287(32):26749-26763.
24. Johnson DL, Mahony JB (2007) Chlamydophila pneumoniae PknD exhibits dual amino acid specificity and phosphorylates Cpn0712, a putative type III secretion YscD homolog. J Bacteriol 189(21):7549-7555. (Pubitemid 350035063)
25. Deutsch EW, et al. (2010) A guided tour of the Trans-Proteomic Pipeline. Proteomics 10(6):1150-1159.
26. Kapp EA, et al. (2003) Mining a tandem mass spectrometry database to determine the trends and global factors influencing peptide fragmentation. Anal Chem 75(22):6251-6264. (Pubitemid 37420620)
27. Olsen JV, et al. (2007) Higher-energy C-trap dissociation for peptide modification analysis. Nat Methods 4(9):709-712. (Pubitemid 47338163)
28. Zhang G, Neubert TA (2011) Comparison of three quantitative phosphoproteomic strategies to study receptor tyrosine kinase signaling. J Proteome Res 10(12):5454-5462.
29. Grundner C, Gay LM, Alber T (2005) Mycobacterium tuberculosis serine/threonine kinases PknB, PknD, PknE, and PknF phosphorylate multiple FHA domains. Protein Sci 14(7):1918-1921. (Pubitemid 40994163)
30. Roumestand C, et al. (2011) Structural insight into the Mycobacterium tuberculosis Rv0020c protein and its interaction with the PknB kinase. Structure 19(10):1525-1534.
31. Macek B, et al. (2007) The serine/threonine/tyrosine phosphoproteome of the model bacterium Bacillus subtilis. Mol Cell Proteomics 6(4):697-707. (Pubitemid 46630102)
32. Schubert OT, et al. (2013) The Mtb proteome library: A resource of assays to quantify the complete proteome of Mycobacterium tuberculosis. Cell Host Microbe 13(5):602-612.
33. Durán R, et al. (2005) Conserved autophosphorylation pattern in activation loops and juxtamembrane regions of Mycobacterium tuberculosis Ser/Thr protein kinases. Biochem Biophys Res Commun 333(3):858-867. (Pubitemid 40854238)
34. Villarino A, et al. (2005) Proteomic identification of M. tuberculosis protein kinase substrates: PknB recruits GarA, a FHA domain-containing protein, through activation loop-mediated interactions. J Mol Biol 350(5):953-963. (Pubitemid 40943454)
35. Ortega C, et al. (2014) Mycobacterium tuberculosis Ser/Thr protein kinase B mediates an oxygen-dependent replication switch. PLoS Biol 12(1):e1001746.
36. Grundner C, Cox JS, Alber T (2008) Protein tyrosine phosphatase PtpA is not required for Mycobacterium tuberculosis growth in mice. FEMS Microbiol Lett 287(2):181-184.
37. Bach H, Papavinasasundaram KG, Wong D, Hmama Z, Av-Gay Y (2008) Mycobacterium tuberculosis virulence is mediated by PtpA dephosphorylation of human vacuolar protein sorting 33B. Cell Host Microbe 3(5):316-322. (Pubitemid 351635998)
38. Kremer L, et al. (2001) Galactan biosynthesis in Mycobacterium tuberculosis. Identification of a bifunctional UDP-galactofuranosyltransferase. J Biol Chem 276(28):26430-26440.
39. Sambou T, et al. (2008) Capsular glucan and intracellular glycogen of Mycobacterium tuberculosis: Biosynthesis and impact on the persistence in mice. Mol Microbiol 70(3):762-774.
40. Gee CL, et al. (2012) A phosphorylated pseudokinase complex controls cell wall synthesis in mycobacteria. Sci Signal 5(208):ra7.
41. Villén J, Gygi SP (2008) The SCX/IMAC enrichment approach for global phosphorylation analysis by mass spectrometry. Nat Protoc 3(10):1630-1638.
42. Kessner D, Chambers M, Burke R, Agus D, Mallick P (2008) ProteoWizard: Open source software for rapid proteomics tools development. Bioinformatics 24(21):2534-2536.
43. Martens L, et al. (2011) mzML - a community standard for mass spectrometry data. Mol Cell Proteomics 10(1):R110.000133.
44. Keller A, Nesvizhskii AI, Kolker E, Aebersold R (2002) Empirical statistical model to estimate the accuracy of peptide identifications made by MS/MS and database search. Anal Chem 74(20):5383-5392. (Pubitemid 35215372)
45. Shteynberg D, et al. (2011) iProphet: Multi-level integrative analysis of shotgun proteomic data improves peptide and protein identification rates and error estimates. Mol Cell Proteomics 10(12):M111.007690.
46. Eng JK, Jahan TA, Hoopmann MR (2013) Comet: An open-source MS/MS sequence database search tool. Proteomics 13(1):22-24.
47. Craig R, Beavis RC (2004) TANDEM: Matching proteins with tandem mass spectra. Bioinformatics 20(9):1466-1467. (Pubitemid 38931421)