Structural insight into the Mycobacterium tuberculosis Rv0020c protein and its interaction with the PknB kinase

Structure

Volumn 19, Issue 10, 2011, Pages 1525-1534

  Roumestand, Christian ^a,b   Leiba, Jade ^c   Galophe, Nathalie ^a,b   Margeat, Emmanuel ^a,b   Padilla, André ^a,b   Bessin, Yannick ^a,b   Barthe, Philippe ^a,b   Molle, Virginie ^c   Cohen Gonsaud, Martin ^a,b  

^a CENTRE DE BIOCHIMIE STRUCTURALE   (France)

^b UNIV MONTPELLIER   (France)

^c UNIVERSITÉ DE MONTPELLIER   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; BACTERIAL PROTEIN RV0020C; JUXTAMEMBRANE DOMAIN; MEMBRANE PROTEIN; PROTEIN SERINE THREONINE KINASE; PROTEIN SERINE THREONINE KINASE PKNB; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ARTICLE; BACTERIAL MEMBRANE; BINDING AFFINITY; BINDING SITE; CARBOXY TERMINAL SEQUENCE; ENZYME ACTIVE SITE; ENZYME PHOSPHORYLATION; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTEIN INTERACTION; PROTEIN STRUCTURE;

ALANINE; BACTERIAL PROTEINS; BINDING SITES; CATALYTIC DOMAIN; CLONING, MOLECULAR; ESCHERICHIA COLI; FLUORESCENCE POLARIZATION; MAGNETIC RESONANCE SPECTROSCOPY; MEMBRANE PROTEINS; MUTAGENESIS, SITE-DIRECTED; MYCOBACTERIUM TUBERCULOSIS; PHOSPHORYLATION; PLASMIDS; PROTEIN BINDING; PROTEIN FOLDING; PROTEIN INTERACTION MAPPING; PROTEIN-SERINE-THREONINE KINASES; RECOMBINANT PROTEINS; SUBSTRATE SPECIFICITY; THREONINE;

MYCOBACTERIUM TUBERCULOSIS;

EID: 80054078091     PISSN: 09692126     EISSN: 18784186     Source Type: Journal    
DOI: 10.1016/j.str.2011.07.011     Document Type: Article

References (30)

1. T. Alber Signaling mechanisms of the Mycobacterium tuberculosis receptor Ser/Thr protein kinases Curr. Opin. Struct. Biol. 19 2009 650 657
2. L.J. Alderwick, V. Molle, L. Kremer, A.J. Cozzone, T.R. Dafforn, G.S. Besra, and K. Fütterer Molecular structure of EmbR, a response element of Ser/Thr kinase signaling in Mycobacterium tuberculosis Proc. Natl. Acad. Sci. USA 103 2006 2558 2563
3. P. Barthe, C. Roumestand, M.J. Canova, L. Kremer, C. Hurard, V. Molle, and M. Cohen-Gonsaud Dynamic and structural characterization of a bacterial FHA protein reveals a new autoinhibition mechanism Structure 17 2009 568 578
4. I. Callebaut, G. Labesse, P. Durand, A. Poupon, L. Canard, J. Chomilier, B. Henrissat, and J.P. Mornon Deciphering protein sequence information through hydrophobic cluster analysis (HCA): current status and perspectives Cell. Mol. Life Sci. 53 1997 621 645 (Pubitemid 27458280)
5. M. Cohen-Gonsaud, P. Barthe, M.J. Canova, C. Stagier-Simon, L. Kremer, C. Roumestand, and V. Molle The Mycobacterium tuberculosis Ser/Thr kinase substrate Rv2175c is a DNA-binding protein regulated by phosphorylation J. Biol. Chem. 284 2009 19290 19300
6. G. Cornilescu, F. Delaglio, and A. Bax Protein backbone angle restraints from searching a database for chemical shift and sequence homology J. Biomol. NMR 13 1999 289 302 (Pubitemid 29143535)
7. J.M. Curry, R. Whalan, D.M. Hunt, K. Gohil, M. Strom, L. Rickman, M.J. Colston, S.J. Smerdon, and R.S. Buxton An ABC transporter containing a forkhead-associated domain interacts with a serine-threonine protein kinase and is required for growth of Mycobacterium tuberculosis in mice Infect. Immun. 73 2005 4471 4477 (Pubitemid 41105600)
8. R. Durán, A. Villarino, M. Bellinzoni, A. Wehenkel, P. Fernandez, B. Boitel, S.T. Cole, P.M. Alzari, and C. Cerveñansky Conserved autophosphorylation pattern in activation loops and juxtamembrane regions of Mycobacterium tuberculosis Ser/Thr protein kinases Biochem. Biophys. Res. Commun. 333 2005 858 867 (Pubitemid 40854238)
9. P. Fernandez, B. Saint-Joanis, N. Barilone, M. Jackson, B. Gicquel, S.T. Cole, and P.M. Alzari The Ser/Thr protein kinase PknB is essential for sustaining mycobacterial growth J. Bacteriol. 188 2006 7778 7784 (Pubitemid 44764514)
10. M. Fiuza, M.J. Canova, I. Zanella-Cléon, M. Becchi, A.J. Cozzone, L.M. Mateos, L. Kremer, J.A. Gil, and V. Molle From the characterization of the four serine/threonine protein kinases (PknA/B/G/L) of Corynebacterium glutamicum toward the role of PknA and PknB in cell division J. Biol. Chem. 283 2008 18099 18112
11. P. Güntert Automated NMR structure calculation with CYANA Methods Mol. Biol. 278 2004 353 378
12. M. Gupta, A. Sajid, G. Arora, V. Tandon, and Y. Singh Forkhead-associated domain-containing protein Rv0019c and polyketide-associated protein PapA5, from substrates of serine/threonine protein kinase PknB to interacting proteins of Mycobacterium tuberculosis J. Biol. Chem. 284 2009 34723 34734
13. L. Holm, and P. Rosenström Dali server: conservation mapping in 3D Nucleic Acids Res. 38 Web Server issue 2010 W545 W549
14. M. Huse, and J. Kuriyan The conformational plasticity of protein kinases Cell 109 2002 275 282 (Pubitemid 34606870)
15. R. Koradi, M. Billeter, and K. Wuthrich MOLMOL: a program for display and analysis of macromolecular structures J. Mol. Graph 14 1996 51 55 29-32 (Pubitemid 26152976)
16. E. Krissinel, and K. Henrick Secondary-structure matching (SSM), a new tool for fast protein structure alignment in three dimensions Acta Crystallogr. D Biol. Crystallogr. 60 2004 2256 2268 (Pubitemid 41742778)
17. R.A. Laskowski, D.S. Moss, and J.M. Thornton Main-chain bond lengths and bond angles in protein structures J. Mol. Biol. 231 1993 1049 1067 (Pubitemid 23209879)
18. A. Mahajan, C. Yuan, H. Lee, E.S. Chen, P.Y. Wu, and M.D. Tsai Structure and function of the phosphothreonine-specific FHA domain Sci. Signal. 1 2008 re12
19. V. Molle, and L. Kremer Division and cell envelope regulation by Ser/Thr phosphorylation: Mycobacterium shows the way Mol. Microbiol. 75 2010 1064 1077
20. V. Molle, L. Kremer, C. Girard-Blanc, G.S. Besra, A.J. Cozzone, and J.F. Prost An FHA phosphoprotein recognition domain mediates protein EmbR phosphorylation by PknH, a Ser/Thr protein kinase from Mycobacterium tuberculosis Biochemistry 42 2003 15300 15309 (Pubitemid 38031729)
21. V. Molle, D. Soulat, J.M. Jault, C. Grangeasse, A.J. Cozzone, and J.F. Prost Two FHA domains on an ABC transporter, Rv1747, mediate its phosphorylation by PknF, a Ser/Thr protein kinase from Mycobacterium tuberculosis FEMS Microbiol. Lett. 234 2004 215 223 (Pubitemid 38595635)
22. A.J. Nederveen, J.F. Doreleijers, W. Vranken, Z. Miller, C.A. Spronk, S.B. Nabuurs, P. Güntert, M. Livny, J.L. Markley, and M. Nilges RECOORD: a recalculated coordinate database of 500+ proteins from the PDB using restraints from the BioMagResBank Proteins 59 2005 662 672 (Pubitemid 40695843)
23. T.J. Nott, G. Kelly, L. Stach, J. Li, S. Westcott, D. Patel, D.M. Hunt, S. Howell, R.S. Buxton, H.M. O'Hare, and S.J. Smerdon An intramolecular switch regulates phosphoindependent FHA domain interactions in Mycobacterium tuberculosis Sci. Signal. 2 2009 ra12
24. H.M. O'Hare, R. Durán, C. Cerveñansky, M. Bellinzoni, A.M. Wehenkel, O. Pritsch, G. Obal, J. Baumgartner, J. Vialaret, K. Johnsson, and P.M. Alzari Regulation of glutamate metabolism by protein kinases in mycobacteria Mol. Microbiol. 70 2008 1408 1423
25. S. Pennell, S. Westcott, M. Ortiz-Lombardía, D. Patel, J. Li, T.J. Nott, D. Mohammed, R.S. Buxton, M.B. Yaffe, C. Verma, and S.J. Smerdon Structural and functional analysis of phosphothreonine-dependent FHA domain interactions Structure 18 2010 1587 1595
26. J.L. Pons, T.E. Malliavin, and M.A. Delsuc Gifa V. 4: A complete package for NMR data set processing J. Biomol. NMR 8 1996 445 452 (Pubitemid 126706799)
27. C.A. Royer, W.R. Smith, and J.M. Beechem Analysis of binding in macromolecular complexes: a generalized numerical approach Anal. Biochem. 191 1990 287 294
28. M. Sattler, J. Schleucher, and C. Griesinger Heteronuclear multidimensional NMR experiments for the structure determination of proteins in solution employing pulsed field gradients Prog. Nucl. Magn. Reson. Spectrosc. 34 1999 93 158 (Pubitemid 129595216)
29. E.D. Scheef, and P.E. Bourne Structural evolution of the protein kinase-like superfamily PLoS Comput. Biol. 1 2005 e49
30. W. Xia, H. Li, K.H. Sze, and H. Sun Structure of a nickel chaperone, HypA, from Helicobacter pylori reveals two distinct metal binding sites J. Am. Chem. Soc. 131 2009 10031 10040