The Glycosylated Rv1860 Protein of Mycobacterium tuberculosis Inhibits Dendritic Cell Mediated TH1 and TH17 Polarization of T Cells and Abrogates Protective Immunity Conferred by BCG

PLoS Pathogens

Volumn 10, Issue 6, 2014, Pages

  Satchidanandam, Vijaya ^a   Kumar, Naveen ^a   Jumani, Rajiv S ^a   Challu, Vijay ^b   Elangovan, Shobha ^a   Khan, Naseem A ^a  

^a INDIAN INSTITUTE OF SCIENCE   (India)

^b NATIONAL TUBERCULOSIS INSTITUTE   (India)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; GLYCOPROTEIN; INTERLEUKIN 10; INTERLEUKIN 12P40; INTERLEUKIN 12P70; INTERLEUKIN 17; INTERLEUKIN 2; INTERLEUKIN 6; RV1860 GLYCOPROTEIN; UNCLASSIFIED DRUG; AUTACOID; BACTERIAL PROTEIN; BCG VACCINE; RECOMBINANT PROTEIN;

ADAPTIVE IMMUNITY; ANIMAL CELL; ANIMAL MODEL; ARTICLE; BACTERIAL SURVIVAL; BCG VACCINATION; CONTROLLED STUDY; CYTOKINE RELEASE; DENDRITIC CELL; ENZYME LINKED IMMUNOSORBENT ASSAY; GLYCOSYLATION; GUINEA PIG; IMMUNOLOGICAL MEMORY; IMMUNOPRECIPITATION; INNATE IMMUNITY; MACROPHAGE CULTURE; MOUSE; MYCOBACTERIUM BOVIS BCG; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PERITONEUM MACROPHAGE; PLASMID; POLARIZATION; PROTEIN EXPRESSION; SPLEEN CELL; TH1 CELL; TH17 CELL; TUBERCULOSIS; WESTERN BLOTTING; ANIMAL; ANTAGONISTS AND INHIBITORS; BAGG ALBINO MOUSE; CELL CULTURE; CELL POLARITY; FEMALE; GENETICS; IMMUNOLOGY; METABOLISM; MICROBIOLOGY; MYCOBACTERIUM BOVIS; PROTEIN PROCESSING; SECRETION (PROCESS); SPLEEN;

ADAPTIVE IMMUNITY; ANIMALS; BACTERIAL PROTEINS; BCG VACCINE; CELL POLARITY; CELLS, CULTURED; DENDRITIC CELLS; FEMALE; GLYCOPROTEINS; GLYCOSYLATION; IMMUNOLOGIC MEMORY; INFLAMMATION MEDIATORS; MACROPHAGES, PERITONEAL; MICE, INBRED BALB C; MYCOBACTERIUM BOVIS; MYCOBACTERIUM TUBERCULOSIS; PROTEIN PROCESSING, POST-TRANSLATIONAL; RECOMBINANT PROTEINS; SPLEEN; TH1 CELLS; TH17 CELLS; TUBERCULOSIS;

EID: 84903454609     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1004176     Document Type: Article

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