Microbiology: Export-mediated assembly of mycobacterial glycoproteins parallels eukaryotic pathways

Science

Volumn 309, Issue 5736, 2005, Pages 941-943

  VanderVen, Brian C ^a   Harder, Jeffery D ^a   Crick, Dean C ^a   Belisle, John T ^a  

^a Department of Environmental and Radiological Health Sciences   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIA; CELL MEMBRANES; DISEASES; MASS SPECTROMETRY; MICROBIOLOGY;

EUKARYOTIC PROTEINS; MEMBRANE PROTEINS; MYCOBACTERIUM TUBERCULOSIS; PROTEIN O-MANNOSYLATION;

PROTEINS;

BACTERIAL PROTEIN; CHIMERIC PROTEIN; MANNOSYLTRANSFERASE; HYBRID PROTEIN; MANNOPROTEINS; MANNOSE; MEMBRANE PROTEIN; PROTEIN O MANNOSYLTRANSFERASE; PROTEIN O-MANNOSYLTRANSFERASE;

MICROBIOLOGY;

AMINO ACID SEQUENCE; ARTICLE; CATALYST; CELLULAR DISTRIBUTION; CHEMICAL REACTION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME MECHANISM; EUKARYOTE; MASS SPECTROMETRY; MOLECULAR EVOLUTION; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN GLYCOSYLATION; PROTEIN LOCALIZATION; PROTEIN MANNOSYLATION; PROTEIN MODIFICATION; PROTEIN PROCESSING; PROTEIN TRANSPORT; SEQUENCE HOMOLOGY; TRANSPORT KINETICS; EUKARYOTIC CELL; GENETICS; GLYCOSYLATION; METABOLISM; MOLECULAR CLONING; MYCOBACTERIUM SMEGMATIS;

EUKARYOTA; MYCOBACTERIUM TUBERCULOSIS;

CLONING, MOLECULAR; EUKARYOTIC CELLS; EVOLUTION, MOLECULAR; GLYCOSYLATION; MANNOSE; MANNOSYLTRANSFERASES; MEMBRANE GLYCOPROTEINS; MYCOBACTERIUM SMEGMATIS; MYCOBACTERIUM TUBERCULOSIS; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN TRANSPORT; RECOMBINANT FUSION PROTEINS;

EID: 23244440497     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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27. We thank P. J. Hill for technical assistance and W. R. Jacobs Jr. (Howard Hughes Medical Institute, Albert Einstein College of Medicine) for the M. tuberculosis ΔRD1 mutant. This work was supported by NIH National Institute of Allergy and Infectious Diseases grant R01 AI-44042.