Superoxide dismutase 1 mutation in a cellular model of amyotrophic lateral sclerosis shifts energy generation from oxidative phosphorylation to glycolysis

Neurobiology of Aging

Volumn 35, Issue 6, 2014, Pages 1499-1509

  Allen, Scott P ^a   Rajan, Sandeep ^a   Duffy, Lynn ^a   Mortiboys, Heather ^a   Higginbottom, Adrian ^a   Grierson, Andrew J ^a   Shaw, Pamela J ^a  

^a UNIVERSITY OF SHEFFIELD   (United Kingdom)

Author keywords

ALS; Metabolism; Mitochondria; SOD1

Indexed keywords

ADENOSINE TRIPHOSPHATE; COPPER ZINC SUPEROXIDE DISMUTASE; GALACTOSE; GLUCOSE; LONG CHAIN FATTY ACID; SUPEROXIDE DISMUTASE;

ADULT; AMYOTROPHIC LATERAL SCLEROSIS; ARTICLE; CELL ISOLATION; CONTROLLED STUDY; FATTY ACID OXIDATION; FIBROBLAST; FIBROBLAST CULTURE; GENE MUTATION; GLUCOSE TRANSPORT; GLYCOLYSIS; HUMAN; HUMAN CELL; HUMAN TISSUE; MALE; MITOCHONDRIAL RESPIRATION; MITOCHONDRION; OXIDATIVE PHOSPHORYLATION UNCOUPLING; OXYGEN CONSUMPTION; PRIORITY JOURNAL; SKIN BIOPSY; SOD1 GENE; SPARE RESPIRATORY CAPACITY; WESTERN BLOTTING; CELL CULTURE; CYTOLOGY; ENERGY METABOLISM; ENZYMOLOGY; GENETICS; METABOLISM; MIDDLE AGED; MUTATION; OXIDATIVE PHOSPHORYLATION; PATHOLOGY; PHYSIOLOGY; SKIN; ULTRASTRUCTURE;

ADENOSINE TRIPHOSPHATE; ADULT; AMYOTROPHIC LATERAL SCLEROSIS; CELLS, CULTURED; ENERGY METABOLISM; FIBROBLASTS; GLYCOLYSIS; HUMANS; MIDDLE AGED; MITOCHONDRIA; MUTATION; OXIDATIVE PHOSPHORYLATION; SKIN; SUPEROXIDE DISMUTASE;

EID: 84903366159     PISSN: 01974580     EISSN: 15581497     Source Type: Journal    
DOI: 10.1016/j.neurobiolaging.2013.11.025     Document Type: Article

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