메뉴 건너뛰기




Volumn 18, Issue 3, 2014, Pages 220-230

Role of testosterone in the pathogenesis, progression, prognosis and comorbidity of men with chronic kidney disease

Author keywords

Anemia; Cardiovascular disease; Chronic kidney disease; Hypertension; Osteoporosis; Testosterone

Indexed keywords

TESTOSTERONE;

EID: 84903306385     PISSN: 17449979     EISSN: 17449987     Source Type: Journal    
DOI: 10.1111/1744-9987.12101     Document Type: Review
Times cited : (35)

References (129)
  • 1
    • 0026480493 scopus 로고
    • New insights into endocrine disturbances of chronic renal failure
    • Schaefer F, Mehls O, Ritz E. New insights into endocrine disturbances of chronic renal failure. Miner Electrolyte Metab 1992;18:169-173.
    • (1992) Miner Electrolyte Metab , vol.18 , pp. 169-173
    • Schaefer, F.1    Mehls, O.2    Ritz, E.3
  • 3
    • 38949122729 scopus 로고    scopus 로고
    • Testosterone exacerbates obstructive renal injury by stimulating TNF-alpha production and increasing proapoptotic and profibrotic signaling
    • Metcalfe D, Leslie JA, Campbell MT, Meldrum DR, Hile KL, Meldrum KK. Testosterone exacerbates obstructive renal injury by stimulating TNF-alpha production and increasing proapoptotic and profibrotic signaling. Am J Physiol Endocrinol Metab 2008;294:E435-443.
    • (2008) Am J Physiol Endocrinol Metab , vol.294
    • Metcalfe, D.1    Leslie, J.A.2    Campbell, M.T.3    Meldrum, D.R.4    Hile, K.L.5    Meldrum, K.K.6
  • 4
    • 0033983569 scopus 로고    scopus 로고
    • Effect of gender on the progression of nondiabetic renal disease: a meta-analysis
    • Neugarten J, Acharya A, Silbiger SR. Effect of gender on the progression of nondiabetic renal disease: a meta-analysis. J Am Soc Nephrol 2000;11:319-329.
    • (2000) J Am Soc Nephrol , vol.11 , pp. 319-329
    • Neugarten, J.1    Acharya, A.2    Silbiger, S.R.3
  • 5
    • 10744231698 scopus 로고    scopus 로고
    • The rate of progression of renal disease may not be slower in woman compared with men: a patient level meta-analysis
    • Jafar TH, Schmid CH, Stark P etal. The rate of progression of renal disease may not be slower in woman compared with men: a patient level meta-analysis. Nephrol Dial Transplant 2003;18:2047-2053.
    • (2003) Nephrol Dial Transplant , vol.18 , pp. 2047-2053
    • Jafar, T.H.1    Schmid, C.H.2    Stark, P.3
  • 6
    • 82655185120 scopus 로고    scopus 로고
    • Orchiectomy attenuates kidney fibrosis after ureteral obstruction by reduction of oxidative stress in mice
    • Cho MH, Jung KJ, Jang HS, Kim JI, Park KM. Orchiectomy attenuates kidney fibrosis after ureteral obstruction by reduction of oxidative stress in mice. Am J Nephrol 2012;35:7-16.
    • (2012) Am J Nephrol , vol.35 , pp. 7-16
    • Cho, M.H.1    Jung, K.J.2    Jang, H.S.3    Kim, J.I.4    Park, K.M.5
  • 7
    • 33751221329 scopus 로고    scopus 로고
    • Prevalence of hypogonadism in male patients with renal failure
    • Albaaj F, Sivalingham M, Haynes P etal. Prevalence of hypogonadism in male patients with renal failure. Postgrad Med J 2006;82:693-696.
    • (2006) Postgrad Med J , vol.82 , pp. 693-696
    • Albaaj, F.1    Sivalingham, M.2    Haynes, P.3
  • 8
    • 84856813533 scopus 로고    scopus 로고
    • Testosterone deficiency is a cause of anemia and reduced responsiveness to erythropoiesis-stimulating agents in men with chronic kidney disease
    • Carrero JJ, Bárány P, Yilmaz MI etal. Testosterone deficiency is a cause of anemia and reduced responsiveness to erythropoiesis-stimulating agents in men with chronic kidney disease. Nephrol Dial Transplant 2012;27:709-715.
    • (2012) Nephrol Dial Transplant , vol.27 , pp. 709-715
    • Carrero, J.J.1    Bárány, P.2    Yilmaz, M.I.3
  • 9
    • 79960305157 scopus 로고    scopus 로고
    • Endogenous testosterone, endothelial dysfunction, and cardiovascular events in men with nondialysis chronic kidney disease
    • Yilmaz MI, Sonmez A, Qureshi AR etal. Endogenous testosterone, endothelial dysfunction, and cardiovascular events in men with nondialysis chronic kidney disease. Clin J Am Soc Nephrol 2011;6:1617-1625.
    • (2011) Clin J Am Soc Nephrol , vol.6 , pp. 1617-1625
    • Yilmaz, M.I.1    Sonmez, A.2    Qureshi, A.R.3
  • 10
    • 62149122026 scopus 로고    scopus 로고
    • Low serum testosterone increases mortality risk among male dialysis patients
    • Carrero JJ, Qureshi AR, Parini P etal. Low serum testosterone increases mortality risk among male dialysis patients. J Am Soc Nephrol 2009;20:613-620.
    • (2009) J Am Soc Nephrol , vol.20 , pp. 613-620
    • Carrero, J.J.1    Qureshi, A.R.2    Parini, P.3
  • 11
    • 5444224268 scopus 로고    scopus 로고
    • The hypothalamic-pituitary axis in men and women with chronic kidney disease
    • Holley JL. The hypothalamic-pituitary axis in men and women with chronic kidney disease. Adv Chronic Kidney Dis 2004;11:337-341.
    • (2004) Adv Chronic Kidney Dis , vol.11 , pp. 337-341
    • Holley, J.L.1
  • 12
    • 0026620244 scopus 로고
    • Both hyper- and hypogonadotropic hypogonadism occur transiently in acute illness: bio-and immunoactive gonadotropins
    • Spratt DI, Bigos ST, Beitins I, Cox P, Longcope C, Orav J. Both hyper- and hypogonadotropic hypogonadism occur transiently in acute illness: bio-and immunoactive gonadotropins. J Clin Endocrinol Metab 1992;75:1562-1570.
    • (1992) J Clin Endocrinol Metab , vol.75 , pp. 1562-1570
    • Spratt, D.I.1    Bigos, S.T.2    Beitins, I.3    Cox, P.4    Longcope, C.5    Orav, J.6
  • 13
    • 23244441018 scopus 로고    scopus 로고
    • Risk factors for androgen decline in older males: lifestyle, chronic diseases and drugs
    • Isidori AM, Lenzi A. Risk factors for androgen decline in older males: lifestyle, chronic diseases and drugs. J Endocrinol Invest 2005;28(3 Suppl):14S-22.
    • (2005) J Endocrinol Invest , vol.28 , Issue.3 SUPPL.
    • Isidori, A.M.1    Lenzi, A.2
  • 14
    • 67651095865 scopus 로고    scopus 로고
    • Precocious puberty and unlicensed paediatric drugs for severe hyperparathyroidism
    • Bacchetta J, Plotton I, Ranchin B etal. Precocious puberty and unlicensed paediatric drugs for severe hyperparathyroidism. Nephrol Dial Transplant 2009;24:2595-2598.
    • (2009) Nephrol Dial Transplant , vol.24 , pp. 2595-2598
    • Bacchetta, J.1    Plotton, I.2    Ranchin, B.3
  • 16
    • 0027450582 scopus 로고
    • Evidence for attenuation of hypothalamic gonadotropin-releasing hormone (GnRH) impulse strength with preservation of GnRH pulse frequency in men with chronic renal failure
    • Veldhuis JD, Wilkowski MJ, Zwart AD etal. Evidence for attenuation of hypothalamic gonadotropin-releasing hormone (GnRH) impulse strength with preservation of GnRH pulse frequency in men with chronic renal failure. J Clin Endocrinol Metab 1993;76:648-654.
    • (1993) J Clin Endocrinol Metab , vol.76 , pp. 648-654
    • Veldhuis, J.D.1    Wilkowski, M.J.2    Zwart, A.D.3
  • 18
    • 0030991369 scopus 로고    scopus 로고
    • Circulating luteinizing hormone receptor inhibitor(s) in boys with chronic renal failure
    • Dunkel L, Raivio T, Laine J, Holmberg C. Circulating luteinizing hormone receptor inhibitor(s) in boys with chronic renal failure. Kidney Int 1997;51:777-784.
    • (1997) Kidney Int , vol.51 , pp. 777-784
    • Dunkel, L.1    Raivio, T.2    Laine, J.3    Holmberg, C.4
  • 19
    • 0028068482 scopus 로고
    • Less acidic forms of luteinizing hormone are associated with lower testosterone secretion in men on haemodialysis treatment
    • Mitchell R, Bauerfeld C, Schaefer F, Schärer K, Robertson WR. Less acidic forms of luteinizing hormone are associated with lower testosterone secretion in men on haemodialysis treatment. Clin Endocrinol (Oxf) 1994;4:65-73.
    • (1994) Clin Endocrinol (Oxf) , vol.4 , pp. 65-73
    • Mitchell, R.1    Bauerfeld, C.2    Schaefer, F.3    Schärer, K.4    Robertson, W.R.5
  • 20
    • 0020506051 scopus 로고
    • Prolactin suppresses luteinizing hormone secretion and pituitary responsiveness to luteinizing hormone-releasing hormone by a direct action at the anterior pituitary
    • Cheung CY. Prolactin suppresses luteinizing hormone secretion and pituitary responsiveness to luteinizing hormone-releasing hormone by a direct action at the anterior pituitary. Endocrinology 1983;113:632-638.
    • (1983) Endocrinology , vol.113 , pp. 632-638
    • Cheung, C.Y.1
  • 21
    • 0018995819 scopus 로고
    • Prolactin and the control of gonadotropin secretion in the female
    • McNeilly AS. Prolactin and the control of gonadotropin secretion in the female. J Reprod Fertil 1980;58:537-549.
    • (1980) J Reprod Fertil , vol.58 , pp. 537-549
    • McNeilly, A.S.1
  • 22
    • 0036194478 scopus 로고    scopus 로고
    • Sexual hormone abnormalities in male patients with renal failure
    • Schmidt A, Luger A, Hörl WH. Sexual hormone abnormalities in male patients with renal failure. Nephrol Dial Transplant 2002;17:368-371.
    • (2002) Nephrol Dial Transplant , vol.17 , pp. 368-371
    • Schmidt, A.1    Luger, A.2    Hörl, W.H.3
  • 23
    • 0027053265 scopus 로고
    • Endocrine and metabolic disorders following kidney transplantation
    • Feinstein EI, Wanner C, Böhler J, Hörl WH. Endocrine and metabolic disorders following kidney transplantation. Am J Nephrol 1992;12:363-368.
    • (1992) Am J Nephrol , vol.12 , pp. 363-368
    • Feinstein, E.I.1    Wanner, C.2    Böhler, J.3    Hörl, W.H.4
  • 24
    • 0034776981 scopus 로고    scopus 로고
    • Effects of long-term erythropoietin therapy on the hypothalamo-pituitary-testicular axis in male CAPD patients
    • Tokgoz B, Utas C, Dogukan A etal. Effects of long-term erythropoietin therapy on the hypothalamo-pituitary-testicular axis in male CAPD patients. Perit Dial Int 2001;21:448-454.
    • (2001) Perit Dial Int , vol.21 , pp. 448-454
    • Tokgoz, B.1    Utas, C.2    Dogukan, A.3
  • 25
    • 84855169004 scopus 로고    scopus 로고
    • Changes in serum prolactin, sex hormones and thyroid function with alternate nightly nocturnal home dialysis
    • van Eps C, Hawley C, Jeffries J etal. Changes in serum prolactin, sex hormones and thyroid function with alternate nightly nocturnal home dialysis. Nephrology (Carlton) 2012;17:42-47.
    • (2012) Nephrology (Carlton) , vol.17 , pp. 42-47
    • van Eps, C.1    Hawley, C.2    Jeffries, J.3
  • 26
    • 0022035821 scopus 로고
    • Hypothalamic-pituitary gonadal dysfunction in renal failure, dialysis and renal transplantation
    • Handelsman DJ. Hypothalamic-pituitary gonadal dysfunction in renal failure, dialysis and renal transplantation. Endocr Rev 1985;6:151-182.
    • (1985) Endocr Rev , vol.6 , pp. 151-182
    • Handelsman, D.J.1
  • 27
    • 0027523022 scopus 로고
    • Hypothalamo- pituitary gonadal axis in chronic renal failure
    • Handelsman DJ, Dong Q. Hypothalamo- pituitary gonadal axis in chronic renal failure. Endocrinol Metab Clin North Am 1993;22:145-161.
    • (1993) Endocrinol Metab Clin North Am , vol.22 , pp. 145-161
    • Handelsman, D.J.1    Dong, Q.2
  • 28
    • 0026699562 scopus 로고
    • Ambulatory blood pressure monitoring in a nonacademic setting. Effects of age and sex
    • Khoury S, Yarows SA, O'Brien TK, Sowers JR. Ambulatory blood pressure monitoring in a nonacademic setting. Effects of age and sex. Am J Hypertens 1992;5:616-623.
    • (1992) Am J Hypertens , vol.5 , pp. 616-623
    • Khoury, S.1    Yarows, S.A.2    O'Brien, T.K.3    Sowers, J.R.4
  • 29
    • 0028876036 scopus 로고
    • 24-h Ambulatory blood pressure in 352 normal Danish subjects, related to age and gender
    • Wiinberg N, Hoegholm A, Christensen HR etal. 24-h Ambulatory blood pressure in 352 normal Danish subjects, related to age and gender. Am J Hypertens 1995;8(10Pt 1):978-986.
    • (1995) Am J Hypertens , vol.8 , Issue.10 PART 1 , pp. 978-986
    • Wiinberg, N.1    Hoegholm, A.2    Christensen, H.R.3
  • 30
    • 0035714529 scopus 로고    scopus 로고
    • Gender differences in the regulation of blood pressure
    • Reckelhoff JF. Gender differences in the regulation of blood pressure. Hypertension 2001;37:1199-1208.
    • (2001) Hypertension , vol.37 , pp. 1199-1208
    • Reckelhoff, J.F.1
  • 32
    • 0031611277 scopus 로고    scopus 로고
    • Testosterone exacerbates hypertension and reduces pressure-natriuresis in male spontaneously hypertensive rats
    • Reckelhoff JF, Zhang H, Granger JP. Testosterone exacerbates hypertension and reduces pressure-natriuresis in male spontaneously hypertensive rats. Hypertension 1998;31(1 Pt 2):435-439.
    • (1998) Hypertension , vol.31 , Issue.1 PART 2 , pp. 435-439
    • Reckelhoff, J.F.1    Zhang, H.2    Granger, J.P.3
  • 34
    • 0026622937 scopus 로고
    • Androgen-dependent angiotensinogen and renin messenger RNA expression in hypertensive rats
    • Chen YF, Naftilan AJ, Oparil S. Androgen-dependent angiotensinogen and renin messenger RNA expression in hypertensive rats. Hypertension 1992;19:456-463.
    • (1992) Hypertension , vol.19 , pp. 456-463
    • Chen, Y.F.1    Naftilan, A.J.2    Oparil, S.3
  • 35
    • 33750528156 scopus 로고    scopus 로고
    • Androgens potentiate renal vascular responses to angiotensin II via amplification of the Rho kinase signaling pathway
    • Song J, Kost CK, Martin DS. Androgens potentiate renal vascular responses to angiotensin II via amplification of the Rho kinase signaling pathway. Cardiovasc Res 2006;72:456-463.
    • (2006) Cardiovasc Res , vol.72 , pp. 456-463
    • Song, J.1    Kost, C.K.2    Martin, D.S.3
  • 36
    • 74249100627 scopus 로고    scopus 로고
    • Involvement of protein kinase C-CPI-17 in androgen modulation of angiotensin II-renal vasoconstriction
    • Song J, Eyster KM, Kost CK Jr, Kjellsen B, Martin DS. Involvement of protein kinase C-CPI-17 in androgen modulation of angiotensin II-renal vasoconstriction. Cardiovasc Res 2010;85:614-621.
    • (2010) Cardiovasc Res , vol.85 , pp. 614-621
    • Song, J.1    Eyster, K.M.2    Kost Jr, C.K.3    Kjellsen, B.4    Martin, D.S.5
  • 37
    • 0035316139 scopus 로고    scopus 로고
    • Involvement of Rho-kinase in hypertensive vascular disease: a novel therapeutical target in hypertension
    • Mukai Y, Shimokawa H, Matoba T etal. Involvement of Rho-kinase in hypertensive vascular disease: a novel therapeutical target in hypertension. FASEB J 2001;15:1062-1064.
    • (2001) FASEB J , vol.15 , pp. 1062-1064
    • Mukai, Y.1    Shimokawa, H.2    Matoba, T.3
  • 38
    • 33847378025 scopus 로고    scopus 로고
    • Review: epidemiology: testosterone and the metabolic syndrome
    • Svartberg J. Review: epidemiology: testosterone and the metabolic syndrome. Int J Impot Res 2007;19:124-128.
    • (2007) Int J Impot Res , vol.19 , pp. 124-128
    • Svartberg, J.1
  • 39
  • 40
    • 35349019230 scopus 로고    scopus 로고
    • Androgen receptor gene CAG repeat length and body mass index modulate the safety of long-term intramuscular testosterone undecanoate therapy in hypogonadal men
    • Zitzmann M, Nieschlag E. Androgen receptor gene CAG repeat length and body mass index modulate the safety of long-term intramuscular testosterone undecanoate therapy in hypogonadal men. J Clin Endocrinol Metab 2007;92:3844-3853.
    • (2007) J Clin Endocrinol Metab , vol.92 , pp. 3844-3853
    • Zitzmann, M.1    Nieschlag, E.2
  • 41
    • 41449083289 scopus 로고    scopus 로고
    • Gender and human chronic renal disease
    • Silbiger S, Neugarten J. Gender and human chronic renal disease. Gend Med 2008;5(Suppl A):3S-S10.
    • (2008) Gend Med , vol.5 , Issue.SUPPL. A
    • Silbiger, S.1    Neugarten, J.2
  • 42
    • 14044259405 scopus 로고    scopus 로고
    • Gonadal steroid regulation of renal injury in renal wrap hypertension
    • Ji H, Menini S, Mok K etal. Gonadal steroid regulation of renal injury in renal wrap hypertension. Am J Physiol 2005;288:F513-520.
    • (2005) Am J Physiol , vol.288
    • Ji, H.1    Menini, S.2    Mok, K.3
  • 44
    • 61849168856 scopus 로고    scopus 로고
    • Renal phenotype of ET-1 transgenic mice is modulated by androgens
    • Kalk P, Thöne-Reineke C, Schwartz A etal. Renal phenotype of ET-1 transgenic mice is modulated by androgens. Eur J Med Res 2009;14:55-58.
    • (2009) Eur J Med Res , vol.14 , pp. 55-58
    • Kalk, P.1    Thöne-Reineke, C.2    Schwartz, A.3
  • 45
    • 2942702379 scopus 로고    scopus 로고
    • Chronic kidney disease is associated with oxidative stress independent of hypertension
    • Agarwal R. Chronic kidney disease is associated with oxidative stress independent of hypertension. Clin Nephrol 2004;61:377-383.
    • (2004) Clin Nephrol , vol.61 , pp. 377-383
    • Agarwal, R.1
  • 46
    • 0036120783 scopus 로고    scopus 로고
    • Greater oxidative stress in healthy young man compared with premenopausal women
    • Ide T, Tsutsui H, Ohashi N etal. Greater oxidative stress in healthy young man compared with premenopausal women. Arterioscler Thromb Vasc Biol 2002;22:438-442.
    • (2002) Arterioscler Thromb Vasc Biol , vol.22 , pp. 438-442
    • Ide, T.1    Tsutsui, H.2    Ohashi, N.3
  • 47
    • 0036670522 scopus 로고    scopus 로고
    • Endothelin-1 mRNA and protein in vascular wall cells is increased by reactive oxygen species
    • Kaehler J, Sill B, Koester R etal. Endothelin-1 mRNA and protein in vascular wall cells is increased by reactive oxygen species. Clin Sci (Lond) 2002;103(Suppl 48):176S-178.
    • (2002) Clin Sci (Lond) , vol.103 , Issue.SUPPL. 48
    • Kaehler, J.1    Sill, B.2    Koester, R.3
  • 48
    • 0032894945 scopus 로고    scopus 로고
    • Sex hormones and gender-related differences: their influence on chronic renal allograft rejection
    • Müller V, Szabo A, Vicklicky O etal. Sex hormones and gender-related differences: their influence on chronic renal allograft rejection. Kidney Int 1999;55:2011-2020.
    • (1999) Kidney Int , vol.55 , pp. 2011-2020
    • Müller, V.1    Szabo, A.2    Vicklicky, O.3
  • 49
    • 79959236366 scopus 로고    scopus 로고
    • Testosterone increases sodium reabsorption, blood pressure, and renal pathology in female spontaneously hypertensive rats on a high sodium diet
    • Liu B, Ely D. Testosterone increases sodium reabsorption, blood pressure, and renal pathology in female spontaneously hypertensive rats on a high sodium diet. Adv Pharmacol Sci 2011;2011:817835.
    • (2011) Adv Pharmacol Sci , vol.2011 , pp. 817835
    • Liu, B.1    Ely, D.2
  • 50
    • 84455188605 scopus 로고    scopus 로고
    • Relaxin and castration in male mice protect from, but testosterone exacerbates, age-related cardiac and renal fibrosis, whereas estrogens are an independent determinant of organ size
    • Hewitson TD, Zhao C, Wigg B etal. Relaxin and castration in male mice protect from, but testosterone exacerbates, age-related cardiac and renal fibrosis, whereas estrogens are an independent determinant of organ size. Endocrinology 2012;153:188-199.
    • (2012) Endocrinology , vol.153 , pp. 188-199
    • Hewitson, T.D.1    Zhao, C.2    Wigg, B.3
  • 51
    • 68249090577 scopus 로고    scopus 로고
    • Androgen-mediated by apoptosis of kidney tubule cells: role of c-jun amino terminal kinase
    • Verzola D, Villago B, Procopio V etal. Androgen-mediated by apoptosis of kidney tubule cells: role of c-jun amino terminal kinase. Biochem Biophys Res Commun 2009;387:531-536.
    • (2009) Biochem Biophys Res Commun , vol.387 , pp. 531-536
    • Verzola, D.1    Villago, B.2    Procopio, V.3
  • 52
    • 0032799854 scopus 로고    scopus 로고
    • Sex hormones modulate inflammatory mediators produced by macrophages
    • D'Agostino P, Milano S, Barbera C etal. Sex hormones modulate inflammatory mediators produced by macrophages. Ann N Y Acad Sci 1999;876:426-429.
    • (1999) Ann N Y Acad Sci , vol.876 , pp. 426-429
    • D'Agostino, P.1    Milano, S.2    Barbera, C.3
  • 53
    • 0027299544 scopus 로고
    • Effect of gonadal steroids on the production of IL-1 and IL-6 by blood mononuclear cells in vivo
    • Li ZG, Danis VA, Brooks PM. Effect of gonadal steroids on the production of IL-1 and IL-6 by blood mononuclear cells in vivo. Clin Exp Rheumatol 1993;11:157-162.
    • (1993) Clin Exp Rheumatol , vol.11 , pp. 157-162
    • Li, Z.G.1    Danis, V.A.2    Brooks, P.M.3
  • 54
    • 0032981458 scopus 로고    scopus 로고
    • Androgens modulate interleukin-6 production by gingival fibroblasts in vitro
    • Gornstein RA, Lapp CA, Bustos-Valdes SM, Zamorano P. Androgens modulate interleukin-6 production by gingival fibroblasts in vitro. J Periodontol 1999;70:604-609.
    • (1999) J Periodontol , vol.70 , pp. 604-609
    • Gornstein, R.A.1    Lapp, C.A.2    Bustos-Valdes, S.M.3    Zamorano, P.4
  • 55
    • 5744250223 scopus 로고    scopus 로고
    • Androgen receptor cross-talk with cell-signaling pathways
    • Culig Z. Androgen receptor cross-talk with cell-signaling pathways. Growth Factors 2004;22:179-184.
    • (2004) Growth Factors , vol.22 , pp. 179-184
    • Culig, Z.1
  • 56
    • 0037471224 scopus 로고    scopus 로고
    • NF-κB and TNF-α stimulate androgen receptor expression in Sertoli cells
    • Delfino FJ, Boustead JN, Fix C, Walker WH. NF-κB and TNF-α stimulate androgen receptor expression in Sertoli cells. Mol Cell Endocrinol 2003;201:1-12.
    • (2003) Mol Cell Endocrinol , vol.201 , pp. 1-12
    • Delfino, F.J.1    Boustead, J.N.2    Fix, C.3    Walker, W.H.4
  • 57
    • 79551510741 scopus 로고    scopus 로고
    • Testosterone and 17β- estradiol have opposite effects on podocyte apoptosis that precedes glomerulosclerosis in female estrogen receptor knockout mice
    • Doublier S, Lupia E, Catanuto P etal. Testosterone and 17β- estradiol have opposite effects on podocyte apoptosis that precedes glomerulosclerosis in female estrogen receptor knockout mice. Kidney Int 2011;79:404-413.
    • (2011) Kidney Int , vol.79 , pp. 404-413
    • Doublier, S.1    Lupia, E.2    Catanuto, P.3
  • 60
    • 0023841028 scopus 로고
    • Idiopathic membranous nephropathy: the natural history of untreated patients
    • Donadio JV Jr, Torres VE, Velosa JA etal. Idiopathic membranous nephropathy: the natural history of untreated patients. Kidney Int 1988;33:708-715.
    • (1988) Kidney Int , vol.33 , pp. 708-715
    • Donadio Jr, J.V.1    Torres, V.E.2    Velosa, J.A.3
  • 61
    • 67651113994 scopus 로고    scopus 로고
    • Rat mesangial cells exhibit sex-specific profibrotic and proinflammatory phenotypes
    • Pawluczyk IZ, Tan EK, Harris KP. Rat mesangial cells exhibit sex-specific profibrotic and proinflammatory phenotypes. Nephrol Dial Transplant 2009;24:1753-1758.
    • (2009) Nephrol Dial Transplant , vol.24 , pp. 1753-1758
    • Pawluczyk, I.Z.1    Tan, E.K.2    Harris, K.P.3
  • 62
    • 0027937471 scopus 로고
    • Arterial hypertension and microalbuminuria in IDDM: the Italian Microalbuminuria Study
    • Mangili R, Deferrari G, Di Mario U etal. Arterial hypertension and microalbuminuria in IDDM: the Italian Microalbuminuria Study. Diabetologia 1994;37:1015-1024.
    • (1994) Diabetologia , vol.37 , pp. 1015-1024
    • Mangili, R.1    Deferrari, G.2    Di Mario, U.3
  • 63
    • 0033050561 scopus 로고    scopus 로고
    • Progression of diabetic nephropathy in normotensive type 1 diabetic patients
    • Jacobsen P, Rossing K, Tarnow L etal. Progression of diabetic nephropathy in normotensive type 1 diabetic patients. Kidney Int Suppl 1999;71:S101-105.
    • (1999) Kidney Int Suppl , vol.71
    • Jacobsen, P.1    Rossing, K.2    Tarnow, L.3
  • 64
    • 77955926673 scopus 로고    scopus 로고
    • Association between testosterone, estradiol and sex hormone binding globulin levels in men with type 1 diabetes with nephropathy
    • Finn Diane Study Group
    • Maric C, Forsblom C, Thorn L, Waden J, Groop PH, Finn Diane Study Group. Association between testosterone, estradiol and sex hormone binding globulin levels in men with type 1 diabetes with nephropathy. Steroids 2010;75:772-778.
    • (2010) Steroids , vol.75 , pp. 772-778
    • Maric, C.1    Forsblom, C.2    Thorn, L.3    Waden, J.4    Groop, P.H.5
  • 66
    • 84860517474 scopus 로고    scopus 로고
    • Combined inhibition of aromatase activity and dihydrotestosterone supplementation attenuates renal injury in male streptozotocin (STZ)-induced diabetic rats
    • Manigrasso MB, Sawyer RT, Hutchens ZM Jr, Flynn ER, Maric-Bilkan C. Combined inhibition of aromatase activity and dihydrotestosterone supplementation attenuates renal injury in male streptozotocin (STZ)-induced diabetic rats. Am J Physiol Renal Physiol 2012;302:F1203-1209.
    • (2012) Am J Physiol Renal Physiol , vol.302
    • Manigrasso, M.B.1    Sawyer, R.T.2    Hutchens Jr, Z.M.3    Flynn, E.R.4    Maric-Bilkan, C.5
  • 67
    • 68049111587 scopus 로고    scopus 로고
    • Dose-dependent effects of dihydrotestosterone in the streptozocin-induced diabetic rat kidney
    • Xu Q, Prabhu A, Xu S, Manigrasso MB, Maric C. Dose-dependent effects of dihydrotestosterone in the streptozocin-induced diabetic rat kidney. Am J Physiol Renal Physiol 2009;297:F307-315.
    • (2009) Am J Physiol Renal Physiol , vol.297
    • Xu, Q.1    Prabhu, A.2    Xu, S.3    Manigrasso, M.B.4    Maric, C.5
  • 68
    • 0036581047 scopus 로고    scopus 로고
    • Risk factors for development of incipient and overt diabetic nephropathy in type 1 diabetic patients: a 10-year prospective observational study
    • Rossing P, Hougaard P, Parving HH. Risk factors for development of incipient and overt diabetic nephropathy in type 1 diabetic patients: a 10-year prospective observational study. Diabetes Care 2002;25:859-864.
    • (2002) Diabetes Care , vol.25 , pp. 859-864
    • Rossing, P.1    Hougaard, P.2    Parving, H.H.3
  • 69
    • 0033753479 scopus 로고    scopus 로고
    • Risk factors for hip fracture among patients with end-stage renal disease
    • Stehman-Breen CO, Sherrard DJ, Alem AM etal. Risk factors for hip fracture among patients with end-stage renal disease. Kidney Int 2000;58:2200-2205.
    • (2000) Kidney Int , vol.58 , pp. 2200-2205
    • Stehman-Breen, C.O.1    Sherrard, D.J.2    Alem, A.M.3
  • 70
    • 0033920728 scopus 로고    scopus 로고
    • Increased risk of hip fracture among patients with end-stage renal disease
    • Alem AM, Sherrard DJ, Gillen DL etal. Increased risk of hip fracture among patients with end-stage renal disease. Kidney Int 2000;58:396-399.
    • (2000) Kidney Int , vol.58 , pp. 396-399
    • Alem, A.M.1    Sherrard, D.J.2    Gillen, D.L.3
  • 71
    • 53549095197 scopus 로고    scopus 로고
    • Renal function and rate of hip bone loss in older men: the Osteoporotic Fractures in Men Study
    • Ishani A, Paudel M, Taylor BC etal. Renal function and rate of hip bone loss in older men: the Osteoporotic Fractures in Men Study. Osteoporos Int 2008;19:1549-1556.
    • (2008) Osteoporos Int , vol.19 , pp. 1549-1556
    • Ishani, A.1    Paudel, M.2    Taylor, B.C.3
  • 72
    • 0032587613 scopus 로고    scopus 로고
    • Osteoporosis in end-stage renal disease
    • Lindberg JS, Moe S. Osteoporosis in end-stage renal disease. Semin Nephrol 1999;19:115-122.
    • (1999) Semin Nephrol , vol.19 , pp. 115-122
    • Lindberg, J.S.1    Moe, S.2
  • 73
    • 0033550968 scopus 로고    scopus 로고
    • Mortality after all major types of osteoporotic fracture in men and women: an observational study
    • Center JR, Nguyen TV, Schneider D, Sambrook PN, Eisman JA. Mortality after all major types of osteoporotic fracture in men and women: an observational study. Lancet 1999;353:878-882.
    • (1999) Lancet , vol.353 , pp. 878-882
    • Center, J.R.1    Nguyen, T.V.2    Schneider, D.3    Sambrook, P.N.4    Eisman, J.A.5
  • 74
    • 46049083826 scopus 로고    scopus 로고
    • Change in bone mineral density as a function of age in women and men and association with the antiresorptive agents
    • Berger C, Langsetmo L, Joseph L etal. Change in bone mineral density as a function of age in women and men and association with the antiresorptive agents. CMAJ 2008;178:1660-1668.
    • (2008) CMAJ , vol.178 , pp. 1660-1668
    • Berger, C.1    Langsetmo, L.2    Joseph, L.3
  • 75
    • 0034521393 scopus 로고    scopus 로고
    • Relative contributions of testosterone and estrogen in regulating bone resorption and formation in normal elderly men
    • Falahati-Nini A, Riggs BL, Atkinson EJ, O'Fallon WM, Eastell R, Khosla S. Relative contributions of testosterone and estrogen in regulating bone resorption and formation in normal elderly men. J Clin Invest 2000;106:1553-1560.
    • (2000) J Clin Invest , vol.106 , pp. 1553-1560
    • Falahati-Nini, A.1    Riggs, B.L.2    Atkinson, E.J.3    O'Fallon, W.M.4    Eastell, R.5    Khosla, S.6
  • 81
    • 0034864155 scopus 로고    scopus 로고
    • Androgens suppress osteoclast formation induced by RANKL and macrophage-colony stimulating factor
    • Huber DM, Bendixen AC, Pathrose P etal. Androgens suppress osteoclast formation induced by RANKL and macrophage-colony stimulating factor. Endocrinology 2001;142:3800-3808.
    • (2001) Endocrinology , vol.142 , pp. 3800-3808
    • Huber, D.M.1    Bendixen, A.C.2    Pathrose, P.3
  • 83
    • 0030220555 scopus 로고    scopus 로고
    • Effect of dihydrotestosterone alone and combined with estrogen on bone mineral density, bone growth, and formation rates in ovariectomized rats
    • Coxam V, Bowman BM, Mecham M, Roth CM, Miller MA, Miller SC. Effect of dihydrotestosterone alone and combined with estrogen on bone mineral density, bone growth, and formation rates in ovariectomized rats. Bone 1996;19:107-114.
    • (1996) Bone , vol.19 , pp. 107-114
    • Coxam, V.1    Bowman, B.M.2    Mecham, M.3    Roth, C.M.4    Miller, M.A.5    Miller, S.C.6
  • 84
    • 0037172407 scopus 로고    scopus 로고
    • Pathogenesis of bone fragility in women and men
    • Seeman E. Pathogenesis of bone fragility in women and men. Lancet 2002;359:1841-1850.
    • (2002) Lancet , vol.359 , pp. 1841-1850
    • Seeman, E.1
  • 85
    • 62349094837 scopus 로고    scopus 로고
    • Association of reduction in bone mineral density with mortality in male hemodialysis patients
    • Kohno K, Inaba M, Okuno S etal. Association of reduction in bone mineral density with mortality in male hemodialysis patients. Calcif Tissue Int 2009;84:180-185.
    • (2009) Calcif Tissue Int , vol.84 , pp. 180-185
    • Kohno, K.1    Inaba, M.2    Okuno, S.3
  • 86
    • 39049101256 scopus 로고    scopus 로고
    • The effect of sexual hormone abnormalities on proximal femur bone mineral density in hemodialysis patients and the possible role of RANKL
    • Doumouchtsis KK, Kostakis AI, Doumouchtsis SK etal. The effect of sexual hormone abnormalities on proximal femur bone mineral density in hemodialysis patients and the possible role of RANKL. Hemodial Int 2008;12:100-107.
    • (2008) Hemodial Int , vol.12 , pp. 100-107
    • Doumouchtsis, K.K.1    Kostakis, A.I.2    Doumouchtsis, S.K.3
  • 87
    • 33744962693 scopus 로고    scopus 로고
    • Testosterone use in men and its effects on bone health. A systematic review and meta-analysis of randomized placebo-controlled trials
    • Tracz MJ, Sideras K, Bolona ER etal. Testosterone use in men and its effects on bone health. A systematic review and meta-analysis of randomized placebo-controlled trials. J Clin Endocrinol Metab 2006;91:2011-2016.
    • (2006) J Clin Endocrinol Metab , vol.91 , pp. 2011-2016
    • Tracz, M.J.1    Sideras, K.2    Bolona, E.R.3
  • 88
    • 0030899249 scopus 로고    scopus 로고
    • Androgens supplementation in eugonadal men with osteoporosis: effect of six months' treatment on markers of bone formation and resorption
    • Anderson FH, Francis RM, Peaston RT, Wastell HJ. Androgens supplementation in eugonadal men with osteoporosis: effect of six months' treatment on markers of bone formation and resorption. J Bone Miner Res 1997;12:472-478.
    • (1997) J Bone Miner Res , vol.12 , pp. 472-478
    • Anderson, F.H.1    Francis, R.M.2    Peaston, R.T.3    Wastell, H.J.4
  • 89
    • 27844447731 scopus 로고    scopus 로고
    • Anemia and heart failure in chronic kidney disease
    • Locatelli F, Pozzoni P, Del Vecchio L. Anemia and heart failure in chronic kidney disease. Semin Nephrol 2005;25:392-396.
    • (2005) Semin Nephrol , vol.25 , pp. 392-396
    • Locatelli, F.1    Pozzoni, P.2    Del Vecchio, L.3
  • 91
    • 0000552980 scopus 로고
    • Influence of age and sex on hemoglobin: a spectrophotometric analysis of nine hundred and nineteen cases
    • Wiliamson CS. Influence of age and sex on hemoglobin: a spectrophotometric analysis of nine hundred and nineteen cases. Arch Intern Med 1916;18:505-528.
    • (1916) Arch Intern Med , vol.18 , pp. 505-528
    • Wiliamson, C.S.1
  • 92
    • 0001547654 scopus 로고
    • The cause of sex differences in erythrocyte hemoglobin and serum iron levels in human adults
    • Vahlquist B. The cause of sex differences in erythrocyte hemoglobin and serum iron levels in human adults. Blood 1950;5:874-875.
    • (1950) Blood , vol.5 , pp. 874-875
    • Vahlquist, B.1
  • 94
    • 0016805831 scopus 로고
    • Increase in erythroid colony formation in rabbits following the administration of testosterone
    • Moriyama Y, Fischer JW. Increase in erythroid colony formation in rabbits following the administration of testosterone. Proc Soc Exp Biol Med 1975;149:178-180.
    • (1975) Proc Soc Exp Biol Med , vol.149 , pp. 178-180
    • Moriyama, Y.1    Fischer, J.W.2
  • 95
    • 0026101874 scopus 로고
    • Androgens potentiate the effects of erythropoietin in the treatment of anemia of end-stage renal disease
    • Ballal SH, Domoto DT, Polack DC, Marciulonis P, Martin KJ. Androgens potentiate the effects of erythropoietin in the treatment of anemia of end-stage renal disease. Am J Kidney Dis 1991;17:29-33.
    • (1991) Am J Kidney Dis , vol.17 , pp. 29-33
    • Ballal, S.H.1    Domoto, D.T.2    Polack, D.C.3    Marciulonis, P.4    Martin, K.J.5
  • 96
    • 0036936487 scopus 로고    scopus 로고
    • Definition and characterization of relative hypo- and hyperleptinemia in a large Caucasian population
    • Buttner R, Bollheimer LC, Zietz B etal. Definition and characterization of relative hypo- and hyperleptinemia in a large Caucasian population. J Endocrinol 2002;175:745-756.
    • (2002) J Endocrinol , vol.175 , pp. 745-756
    • Buttner, R.1    Bollheimer, L.C.2    Zietz, B.3
  • 97
    • 77957779215 scopus 로고    scopus 로고
    • Testosterone suppresses hepcidin in men: a potential mechanism for testosterone induced erythrocytosis
    • Bachman E, Feng R, Travison T etal. Testosterone suppresses hepcidin in men: a potential mechanism for testosterone induced erythrocytosis. J Clin Endocrinol Metab 2010;95:4743-4747.
    • (2010) J Clin Endocrinol Metab , vol.95 , pp. 4743-4747
    • Bachman, E.1    Feng, R.2    Travison, T.3
  • 100
    • 0021798270 scopus 로고
    • Intramuscular iron replenishment and replacement combined with testosterone enanthate in maintenance hemodialysis anemia: a follow up to 8 years on 16 patients
    • Schustack A, Meshiaj D, Waiss Z, Gotloib L. Intramuscular iron replenishment and replacement combined with testosterone enanthate in maintenance hemodialysis anemia: a follow up to 8 years on 16 patients. Clin Nephrol 1985;23:303-306.
    • (1985) Clin Nephrol , vol.23 , pp. 303-306
    • Schustack, A.1    Meshiaj, D.2    Waiss, Z.3    Gotloib, L.4
  • 101
    • 15044351513 scopus 로고    scopus 로고
    • Renin-angiotensin blockade reduces serum free testosterone in middle-aged men on haemodialysis and correlates with erythropoietin resistance
    • De Long M, Logan JL, Yong KC, Lien YH. Renin-angiotensin blockade reduces serum free testosterone in middle-aged men on haemodialysis and correlates with erythropoietin resistance. Nephrol Dial Transplant 2005;20:585-590.
    • (2005) Nephrol Dial Transplant , vol.20 , pp. 585-590
    • De Long, M.1    Logan, J.L.2    Yong, K.C.3    Lien, Y.H.4
  • 103
    • 33845467935 scopus 로고    scopus 로고
    • Low testosterone and high C-reactive protein concentrations predict low hematocrit in type 2 diabetes
    • Bathia V, Chaudhuri A, Tomar R, Dhindsa S, Ghanim H, Dandona P. Low testosterone and high C-reactive protein concentrations predict low hematocrit in type 2 diabetes. Diabetes Care 2006;29:2289-2294.
    • (2006) Diabetes Care , vol.29 , pp. 2289-2294
    • Bathia, V.1    Chaudhuri, A.2    Tomar, R.3    Dhindsa, S.4    Ghanim, H.5    Dandona, P.6
  • 105
    • 84884333035 scopus 로고    scopus 로고
    • KDIGO clinical practice guideline for anemia in chronic kidney disease
    • Kidney Disease: Improving Global Outcomes (KDIGO) Anemia Work Group
    • Kidney Disease: Improving Global Outcomes (KDIGO) Anemia Work Group. KDIGO clinical practice guideline for anemia in chronic kidney disease. Kidney Int Suppl 2012;2:279-335.
    • (2012) Kidney Int Suppl , vol.2 , pp. 279-335
  • 108
    • 37349118353 scopus 로고    scopus 로고
    • Endogenous testosterone and mortality due to all causes, cardiovascular disease, and cancer in men: European prospective investigation into cancer in Norfolk (EPIC-Norfolk) prospective population study
    • Khaw K, Dowsett M, Folkerd E etal. Endogenous testosterone and mortality due to all causes, cardiovascular disease, and cancer in men: European prospective investigation into cancer in Norfolk (EPIC-Norfolk) prospective population study. Circulation 2007;116:2694-2701.
    • (2007) Circulation , vol.116 , pp. 2694-2701
    • Khaw, K.1    Dowsett, M.2    Folkerd, E.3
  • 109
    • 80054797449 scopus 로고    scopus 로고
    • Hypogonadism as a risk factor for cardiovascular mortality in men: a meta-analytic study
    • Corona G, Rastrelli G, Monami M etal. Hypogonadism as a risk factor for cardiovascular mortality in men: a meta-analytic study. Eur J Endocrinol 2011;165:687-701.
    • (2011) Eur J Endocrinol , vol.165 , pp. 687-701
    • Corona, G.1    Rastrelli, G.2    Monami, M.3
  • 110
    • 84858301672 scopus 로고    scopus 로고
    • Connecting the lines between hypogonadism and atherosclerosis
    • Fahed AC, Gholmieh JM, Azar ST. Connecting the lines between hypogonadism and atherosclerosis. Int J Endocrinol 2012;2012:793953.
    • (2012) Int J Endocrinol , vol.2012 , pp. 793953
    • Fahed, A.C.1    Gholmieh, J.M.2    Azar, S.T.3
  • 111
    • 2442681474 scopus 로고    scopus 로고
    • Cardiac disease in maintenance hemodialysis patients: results of the HEMO Study
    • Cheung AK, Sarnak MJ, Yan G etal. Cardiac disease in maintenance hemodialysis patients: results of the HEMO Study. Kidney Int 2004;65:2380-2389.
    • (2004) Kidney Int , vol.65 , pp. 2380-2389
    • Cheung, A.K.1    Sarnak, M.J.2    Yan, G.3
  • 112
    • 4644221457 scopus 로고    scopus 로고
    • Chronic kidney disease and the risk of death, cardiovascular events, and hospitalization
    • Go AS, Chertow GM, Fan D, McCulloch CE, Hsu C. Chronic kidney disease and the risk of death, cardiovascular events, and hospitalization. N Engl J Med 2004;351:1296-1305.
    • (2004) N Engl J Med , vol.351 , pp. 1296-1305
    • Go, A.S.1    Chertow, G.M.2    Fan, D.3    McCulloch, C.E.4    Hsu, C.5
  • 113
    • 77958516822 scopus 로고    scopus 로고
    • Inflammation in end stage renal disease-what have we learned in 10 years?
    • Carrero JJ, Stenvinkel P. Inflammation in end stage renal disease-what have we learned in 10 years? Semin Dial 2010;23:498-509.
    • (2010) Semin Dial , vol.23 , pp. 498-509
    • Carrero, J.J.1    Stenvinkel, P.2
  • 114
    • 33846423155 scopus 로고    scopus 로고
    • Androgen deficiency and endothelial dysfunction in men with end-stage kidney disease receiving maintenance hemodialysis
    • Karakitsos D, Patrianakos AP, De Groot E etal. Androgen deficiency and endothelial dysfunction in men with end-stage kidney disease receiving maintenance hemodialysis. Am J Nephrol 2006;26:536-543.
    • (2006) Am J Nephrol , vol.26 , pp. 536-543
    • Karakitsos, D.1    Patrianakos, A.P.2    De Groot, E.3
  • 115
    • 79951566257 scopus 로고    scopus 로고
    • Low serum testosterone is associated with increased mortality in men with stage 3 or greater nephropathy
    • Haring R, Nauck M, Völzke H etal. Low serum testosterone is associated with increased mortality in men with stage 3 or greater nephropathy. Am J Nephrol 2011;33:209-217.
    • (2011) Am J Nephrol , vol.33 , pp. 209-217
    • Haring, R.1    Nauck, M.2    Völzke, H.3
  • 116
    • 77955171788 scopus 로고    scopus 로고
    • Associations of estradiol and testosterone with serum phosphorus in older men: the Osteoporotic Fractures in Men study
    • Meng J, Ohlsson C, Laughlin GA etal. Associations of estradiol and testosterone with serum phosphorus in older men: the Osteoporotic Fractures in Men study. Kidney Int 2010;78:415-422.
    • (2010) Kidney Int , vol.78 , pp. 415-422
    • Meng, J.1    Ohlsson, C.2    Laughlin, G.A.3
  • 117
    • 20544433192 scopus 로고    scopus 로고
    • Serum phosphate levels and mortality risk among people with chronic kidney disease
    • Kestenbaum B, Sampson JN, Rudser KD etal. Serum phosphate levels and mortality risk among people with chronic kidney disease. J Am Soc Nephrol 2005;16:520-528.
    • (2005) J Am Soc Nephrol , vol.16 , pp. 520-528
    • Kestenbaum, B.1    Sampson, J.N.2    Rudser, K.D.3
  • 118
    • 0033451202 scopus 로고    scopus 로고
    • Relationship between some prognostics marker of HD patients and serum erythropoietin, insulin-like growth factor-1, leptin, parathormone and testosterone
    • Majdan M, Kotarski J, Ksiazek A, Grzebalska A. Relationship between some prognostics marker of HD patients and serum erythropoietin, insulin-like growth factor-1, leptin, parathormone and testosterone. Int Urol Nephrol 1999;31:563-569.
    • (1999) Int Urol Nephrol , vol.31 , pp. 563-569
    • Majdan, M.1    Kotarski, J.2    Ksiazek, A.3    Grzebalska, A.4
  • 119
    • 78149348155 scopus 로고    scopus 로고
    • Endogenous testosterone and mortality in male hemodialysis patients: is it the result of aging?
    • Gungor O, Kircelli F, Carrero JJ etal. Endogenous testosterone and mortality in male hemodialysis patients: is it the result of aging? Clin J Am Soc Nephrol 2010;5:2018-2023.
    • (2010) Clin J Am Soc Nephrol , vol.5 , pp. 2018-2023
    • Gungor, O.1    Kircelli, F.2    Carrero, J.J.3
  • 120
    • 84864836268 scopus 로고    scopus 로고
    • The aging of the endocrine hypothalamus and its dependent endocrine glands
    • Batrinos ML. The aging of the endocrine hypothalamus and its dependent endocrine glands. Hormones (Athens) 2012;11:241-253.
    • (2012) Hormones (Athens) , vol.11 , pp. 241-253
    • Batrinos, M.L.1
  • 121
    • 78650630599 scopus 로고    scopus 로고
    • Prevalence and clinical implications of testosterone deficiency in men with end-stage renal disease
    • Carrero JJ, Qureshi AR, Nakashima A etal. Prevalence and clinical implications of testosterone deficiency in men with end-stage renal disease. Nephrol Dial Transplant 2011;26:184-190.
    • (2011) Nephrol Dial Transplant , vol.26 , pp. 184-190
    • Carrero, J.J.1    Qureshi, A.R.2    Nakashima, A.3
  • 122
    • 80053203340 scopus 로고    scopus 로고
    • Low testosterone, arterial stiffness and mortality in male haemodialysis patients
    • Kyriazis J, Tzanakis I, Stylianou K etal. Low testosterone, arterial stiffness and mortality in male haemodialysis patients. Nephrol Dial Transplant 2011;26:2971-2977.
    • (2011) Nephrol Dial Transplant , vol.26 , pp. 2971-2977
    • Kyriazis, J.1    Tzanakis, I.2    Stylianou, K.3
  • 123
    • 0031733696 scopus 로고    scopus 로고
    • Clinical epidemiology of cardiovascular disease in chronic renal failure
    • Foley RN, Parfrey PS, Sarnak MJ. Clinical epidemiology of cardiovascular disease in chronic renal failure. Am J Kidney Dis 1998;32(5 Suppl 3):112S-119.
    • (1998) Am J Kidney Dis , vol.32 , Issue.5 SUPPL. 3
    • Foley, R.N.1    Parfrey, P.S.2    Sarnak, M.J.3
  • 124
    • 33645473865 scopus 로고    scopus 로고
    • Endothelial dysfunction and the kidney: emerging risk factors for renal insufficiency and cardiovascular outcomes in essential hypertension
    • Zoccali C. Endothelial dysfunction and the kidney: emerging risk factors for renal insufficiency and cardiovascular outcomes in essential hypertension. J Am Soc Nephrol 2006;17(4 Suppl 2):61S-63.
    • (2006) J Am Soc Nephrol , vol.17 , Issue.4 SUPPL. 2
    • Zoccali, C.1
  • 125
    • 76749150027 scopus 로고    scopus 로고
    • Vascular disease and chronic renal failure: new insights
    • Nanayakkara PW, Gaillard CA. Vascular disease and chronic renal failure: new insights. Neth J Med 2010;68:5-14.
    • (2010) Neth J Med , vol.68 , pp. 5-14
    • Nanayakkara, P.W.1    Gaillard, C.A.2
  • 126
    • 84859131983 scopus 로고    scopus 로고
    • Gonadal dysfunction in men with chronic kidney disease: clinical features, prognostic implications and therapeutical options
    • Iglesias P, Carrero JJ, Diez JJ. Gonadal dysfunction in men with chronic kidney disease: clinical features, prognostic implications and therapeutical options. J Nephrol 2012;25:31-42.
    • (2012) J Nephrol , vol.25 , pp. 31-42
    • Iglesias, P.1    Carrero, J.J.2    Diez, J.J.3
  • 127
    • 84869444564 scopus 로고    scopus 로고
    • The vulnerable man: impact of testosterone deficiency on the uraemic phenotype
    • Carrero JJ, Stenvinkel P. The vulnerable man: impact of testosterone deficiency on the uraemic phenotype. Nephrol Dial Transplant 2012;27:4030-4041.
    • (2012) Nephrol Dial Transplant , vol.27 , pp. 4030-4041
    • Carrero, J.J.1    Stenvinkel, P.2
  • 128
    • 84864297656 scopus 로고    scopus 로고
    • Testosterone supplementation in heart failure: a meta-analysis
    • Toma M, McAlister FA, Coglianese EE etal. Testosterone supplementation in heart failure: a meta-analysis. Circ Heart Fail 2012;5:315-321.
    • (2012) Circ Heart Fail , vol.5 , pp. 315-321
    • Toma, M.1    McAlister, F.A.2    Coglianese, E.E.3
  • 129
    • 76149108405 scopus 로고    scopus 로고
    • Extremes of endogenous testosterone are associated with increased risk of incident coronary events in older women
    • Laughlin GA, Goodell V, Barrett-Conor E. Extremes of endogenous testosterone are associated with increased risk of incident coronary events in older women. J Clin Endocrinol Metab 2010;95:740-747.
    • (2010) J Clin Endocrinol Metab , vol.95 , pp. 740-747
    • Laughlin, G.A.1    Goodell, V.2    Barrett-Conor, E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.