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Volumn 72, Issue 3, 2006, Pages 456-463

Androgens potentiate renal vascular responses to angiotensin II via amplification of the Rho kinase signaling pathway

Author keywords

Angiotensin; Gender; Hypertension; Protein kinase; Vasoconstriction

Indexed keywords

ANDROGEN; ANGIOTENSIN 1 RECEPTOR; ANGIOTENSIN II; ENZYME; FASUDIL; MYOSIN PHOSPHATASE TARGET SUBUNIT 1; RHO KINASE; TESTOSTERONE; UNCLASSIFIED DRUG;

EID: 33750528156     PISSN: 00086363     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cardiores.2006.09.007     Document Type: Article
Times cited : (46)

References (46)
  • 2
    • 0035714529 scopus 로고    scopus 로고
    • Gender differences in the regulation of blood pressure
    • Reckelhoff J.F. Gender differences in the regulation of blood pressure. Hypertension 37 (2001) 1199-1208
    • (2001) Hypertension , vol.37 , pp. 1199-1208
    • Reckelhoff, J.F.1
  • 3
    • 13144256679 scopus 로고    scopus 로고
    • Sex steroids, cardiovascular disease, and hypertension: unanswered questions and some speculations
    • Reckelhoff J.F. Sex steroids, cardiovascular disease, and hypertension: unanswered questions and some speculations. Hypertension 45 (2005) 170-174
    • (2005) Hypertension , vol.45 , pp. 170-174
    • Reckelhoff, J.F.1
  • 4
    • 0026577144 scopus 로고
    • Role of gonadal hormones in hypertension in the Dahl salt-sensitive rat
    • Rowland N.E., and Fregly M.J. Role of gonadal hormones in hypertension in the Dahl salt-sensitive rat. Clin Exp Hypertens A 14 (1992) 367-375
    • (1992) Clin Exp Hypertens A , vol.14 , pp. 367-375
    • Rowland, N.E.1    Fregly, M.J.2
  • 5
    • 0026074118 scopus 로고
    • Sexual dimorphism of blood pressure in spontaneously hypertensive rats is androgen dependent
    • Chen Y.F., and Meng Q.C. Sexual dimorphism of blood pressure in spontaneously hypertensive rats is androgen dependent. Life Sci 48 (1991) 85-96
    • (1991) Life Sci , vol.48 , pp. 85-96
    • Chen, Y.F.1    Meng, Q.C.2
  • 6
    • 0024445330 scopus 로고
    • Sexual dimorphism of blood pressure in spontaneously hypertensive rats: effects of anti-androgen treatment
    • Ganten U., Schroder G., Witt M., Zimmermann F., Stock D., and Stock G. Sexual dimorphism of blood pressure in spontaneously hypertensive rats: effects of anti-androgen treatment. J Hypertens 7 (1989) 721-726
    • (1989) J Hypertens , vol.7 , pp. 721-726
    • Ganten, U.1    Schroder, G.2    Witt, M.3    Zimmermann, F.4    Stock, D.5    Stock, G.6
  • 7
    • 0031611277 scopus 로고    scopus 로고
    • Testosterone exacerbates hypertension and reduces pressure-natriuresis in male spontaneously hypertensive rats
    • Reckelhoff J.F., Zhang H., and Granger J.P. Testosterone exacerbates hypertension and reduces pressure-natriuresis in male spontaneously hypertensive rats. Hypertension 31 (1998) 435-439
    • (1998) Hypertension , vol.31 , pp. 435-439
    • Reckelhoff, J.F.1    Zhang, H.2    Granger, J.P.3
  • 8
    • 0033071123 scopus 로고    scopus 로고
    • Role of androgens in mediating hypertension and renal injury
    • Reckelhoff J.F., and Granger J.P. Role of androgens in mediating hypertension and renal injury. Clin Exp Pharmacol Physiol 26 (1999) 127-131
    • (1999) Clin Exp Pharmacol Physiol , vol.26 , pp. 127-131
    • Reckelhoff, J.F.1    Granger, J.P.2
  • 10
    • 33744808519 scopus 로고    scopus 로고
    • Androgens augment renal vascular responses to ANG II in New Zealand genetically hypertensive rats
    • Song J., Kost Jr. C.K., and Martin D.S. Androgens augment renal vascular responses to ANG II in New Zealand genetically hypertensive rats. Am J Physiol Regul Integr Comp Physiol 290 (2006) R1608-R1615
    • (2006) Am J Physiol Regul Integr Comp Physiol , vol.290
    • Song, J.1    Kost Jr., C.K.2    Martin, D.S.3
  • 11
    • 0037340168 scopus 로고    scopus 로고
    • The kidney, hypertension, and obesity
    • Hall J.E. The kidney, hypertension, and obesity. Hypertension 41 (2003) 625-633
    • (2003) Hypertension , vol.41 , pp. 625-633
    • Hall, J.E.1
  • 12
    • 0035654480 scopus 로고    scopus 로고
    • Renal transplantation studies in genetic hypertension
    • Grisk O., and Rettig R. Renal transplantation studies in genetic hypertension. News Physiol Sci 16 (2001) 262-265
    • (2001) News Physiol Sci , vol.16 , pp. 262-265
    • Grisk, O.1    Rettig, R.2
  • 13
    • 0026011776 scopus 로고
    • Sexual dimorphism in renal function and hormonal status of New Zealand genetically hypertensive rats
    • Ashton N., and Balment R.J. Sexual dimorphism in renal function and hormonal status of New Zealand genetically hypertensive rats. Acta Endocrinol (Copenh) 124 (1991) 91-97
    • (1991) Acta Endocrinol (Copenh) , vol.124 , pp. 91-97
    • Ashton, N.1    Balment, R.J.2
  • 14
    • 0036762815 scopus 로고    scopus 로고
    • Recent advances in angiotensin II signaling
    • Touyz R.M., and Berry C. Recent advances in angiotensin II signaling. Braz J Med Biol Res 35 (2002) 1001-1015
    • (2002) Braz J Med Biol Res , vol.35 , pp. 1001-1015
    • Touyz, R.M.1    Berry, C.2
  • 15
    • 0037675052 scopus 로고    scopus 로고
    • The role of angiotensin II in regulating vascular structural and functional changes in hypertension
    • Touyz R.M. The role of angiotensin II in regulating vascular structural and functional changes in hypertension. Curr Hypertens Rep 5 (2003) 155-164
    • (2003) Curr Hypertens Rep , vol.5 , pp. 155-164
    • Touyz, R.M.1
  • 16
    • 0041883696 scopus 로고    scopus 로고
    • Effects of angiotensin II, arginine vasopressin and thromboxane A2 in renal vascular bed: role of Rho-kinase
    • Cavarape A., Bauer J., Bartoli E., Endlich K., and Parekh N. Effects of angiotensin II, arginine vasopressin and thromboxane A2 in renal vascular bed: role of Rho-kinase. Nephrol Dial Transplant 18 (2003) 1764-1769
    • (2003) Nephrol Dial Transplant , vol.18 , pp. 1764-1769
    • Cavarape, A.1    Bauer, J.2    Bartoli, E.3    Endlich, K.4    Parekh, N.5
  • 17
    • 0034650714 scopus 로고    scopus 로고
    • Signal transduction by G-proteins, Rho-kinase and protein phosphatase to smooth muscle and non-muscle myosin II
    • Somlyo A.P., and Somlyo A.V. Signal transduction by G-proteins, Rho-kinase and protein phosphatase to smooth muscle and non-muscle myosin II. J Physiol 522 Pt 2 (2000) 177-185
    • (2000) J Physiol , vol.522 , Issue.PART 2 , pp. 177-185
    • Somlyo, A.P.1    Somlyo, A.V.2
  • 18
    • 0035316139 scopus 로고    scopus 로고
    • Involvement of Rho-kinase in hypertensive vascular disease: a novel therapeutic target in hypertension
    • Mukai Y., Shimokawa H., Matoba T., Kandabashi T., Satoh S., Hiroki J., et al. Involvement of Rho-kinase in hypertensive vascular disease: a novel therapeutic target in hypertension. FASEB J 15 (2001) 1062-1064
    • (2001) FASEB J , vol.15 , pp. 1062-1064
    • Mukai, Y.1    Shimokawa, H.2    Matoba, T.3    Kandabashi, T.4    Satoh, S.5    Hiroki, J.6
  • 20
    • 0033135921 scopus 로고    scopus 로고
    • The Rho-related protein Rnd1 inhibits Ca2+ sensitization of rat smooth muscle
    • Loirand G., Cario-Toumaniantz C., Chardin P., and Pacaud P. The Rho-related protein Rnd1 inhibits Ca2+ sensitization of rat smooth muscle. J Physiol 516 Pt 3 (1999) 825-834
    • (1999) J Physiol , vol.516 , Issue.PART 3 , pp. 825-834
    • Loirand, G.1    Cario-Toumaniantz, C.2    Chardin, P.3    Pacaud, P.4
  • 21
    • 4344681450 scopus 로고    scopus 로고
    • Evidence that estrogen suppresses Rho-kinase function in the cerebral circulation in vivo
    • Chrissobolis S., Budzyn K., Marley P.D., and Sobey C.G. Evidence that estrogen suppresses Rho-kinase function in the cerebral circulation in vivo. Stroke 35 (2004) 2200-2205
    • (2004) Stroke , vol.35 , pp. 2200-2205
    • Chrissobolis, S.1    Budzyn, K.2    Marley, P.D.3    Sobey, C.G.4
  • 22
    • 28444461454 scopus 로고    scopus 로고
    • Inhibition of RhoA/Rho kinase pathway is involved in the beneficial effect of sildenafil on pulmonary hypertension
    • Guilluy C., Sauzeau V., Rolli-Derkinderen M., Guerin P., Sagan C., Pacaud P., et al. Inhibition of RhoA/Rho kinase pathway is involved in the beneficial effect of sildenafil on pulmonary hypertension. Br J Pharmacol 146 (2005) 1010-1018
    • (2005) Br J Pharmacol , vol.146 , pp. 1010-1018
    • Guilluy, C.1    Sauzeau, V.2    Rolli-Derkinderen, M.3    Guerin, P.4    Sagan, C.5    Pacaud, P.6
  • 23
    • 2342580708 scopus 로고    scopus 로고
    • RhoA activation in vascular smooth muscle cells from stroke-prone spontaneously hypertensive rats
    • Moriki N., Ito M., Seko T., Kureishi Y., Okamoto R., Nakakuki T., et al. RhoA activation in vascular smooth muscle cells from stroke-prone spontaneously hypertensive rats. Hypertens Res 27 (2004) 263-270
    • (2004) Hypertens Res , vol.27 , pp. 263-270
    • Moriki, N.1    Ito, M.2    Seko, T.3    Kureishi, Y.4    Okamoto, R.5    Nakakuki, T.6
  • 24
    • 9644280885 scopus 로고    scopus 로고
    • Hypertension and RhoA/Rho-kinase signaling in the vasculature: highlights from the recent literature
    • Lee D.L., Webb R.C., and Jin L. Hypertension and RhoA/Rho-kinase signaling in the vasculature: highlights from the recent literature. Hypertension 44 (2004) 796-799
    • (2004) Hypertension , vol.44 , pp. 796-799
    • Lee, D.L.1    Webb, R.C.2    Jin, L.3
  • 25
    • 0032735745 scopus 로고    scopus 로고
    • Gender differences in hypertension in spontaneously hypertensive rats: role of androgens and androgen receptor
    • Reckelhoff J.F., Zhang H., Srivastava K., and Granger J.P. Gender differences in hypertension in spontaneously hypertensive rats: role of androgens and androgen receptor. Hypertension 34 (1999) 920-923
    • (1999) Hypertension , vol.34 , pp. 920-923
    • Reckelhoff, J.F.1    Zhang, H.2    Srivastava, K.3    Granger, J.P.4
  • 27
    • 0021243060 scopus 로고
    • Body sodium level in hypertensive and normotensive rats: effects of dietary sodium levels and sodium loads
    • Simpson F.O., Ledingham J.M., and Phelan E.L. Body sodium level in hypertensive and normotensive rats: effects of dietary sodium levels and sodium loads. J Cardiovasc Pharmacol 6 Suppl 1 (1984) S121-S125
    • (1984) J Cardiovasc Pharmacol , vol.6 , Issue.SUPPL. 1
    • Simpson, F.O.1    Ledingham, J.M.2    Phelan, E.L.3
  • 28
    • 0025288625 scopus 로고
    • Abnormal pressure natriuresis. A cause or a consequence of hypertension?
    • Hall J.E., Mizelle H.L., Hildebrandt D.A., and Brands M.W. Abnormal pressure natriuresis. A cause or a consequence of hypertension?. Hypertension 15 (1990) 547-559
    • (1990) Hypertension , vol.15 , pp. 547-559
    • Hall, J.E.1    Mizelle, H.L.2    Hildebrandt, D.A.3    Brands, M.W.4
  • 29
    • 0028295512 scopus 로고
    • Vascular reactivity to angiotensin II is selectively enhanced in the kidneys of spontaneously hypertensive rats
    • Kost Jr. C.K., Herzer W.A., Li P., and Jackson E.K. Vascular reactivity to angiotensin II is selectively enhanced in the kidneys of spontaneously hypertensive rats. J Pharmacol Exp Ther 269 (1994) 82-88
    • (1994) J Pharmacol Exp Ther , vol.269 , pp. 82-88
    • Kost Jr., C.K.1    Herzer, W.A.2    Li, P.3    Jackson, E.K.4
  • 30
    • 0033977726 scopus 로고    scopus 로고
    • Gender differences in development of hypertension in spontaneously hypertensive rats: role of the renin-angiotensin system
    • Reckelhoff J.F., Zhang H., and Srivastava K. Gender differences in development of hypertension in spontaneously hypertensive rats: role of the renin-angiotensin system. Hypertension 35 (2000) 480-483
    • (2000) Hypertension , vol.35 , pp. 480-483
    • Reckelhoff, J.F.1    Zhang, H.2    Srivastava, K.3
  • 31
    • 0036180274 scopus 로고    scopus 로고
    • Androgen dependent expression of AT1 receptor and its regulation of anion secretion in rat epididymis
    • Leung P.S., Wong T.P., Chung Y.W., and Chan H.C. Androgen dependent expression of AT1 receptor and its regulation of anion secretion in rat epididymis. Cell Biol Int 26 (2002) 117-122
    • (2002) Cell Biol Int , vol.26 , pp. 117-122
    • Leung, P.S.1    Wong, T.P.2    Chung, Y.W.3    Chan, H.C.4
  • 32
    • 0037384395 scopus 로고    scopus 로고
    • Regulation of force in vascular smooth muscle
    • Ogut O., and Brozovich F.V. Regulation of force in vascular smooth muscle. J Mol Cell Cardiol 35 (2003) 347-355
    • (2003) J Mol Cell Cardiol , vol.35 , pp. 347-355
    • Ogut, O.1    Brozovich, F.V.2
  • 33
    • 0141751697 scopus 로고    scopus 로고
    • Ca2+ sensitivity of smooth muscle and non-muscle myosin II: modulated by G proteins, kinases, and myosin phosphatase
    • Somlyo A.P., and Somlyo A.V. Ca2+ sensitivity of smooth muscle and non-muscle myosin II: modulated by G proteins, kinases, and myosin phosphatase. Physiol Rev 83 (2003) 1325-1358
    • (2003) Physiol Rev , vol.83 , pp. 1325-1358
    • Somlyo, A.P.1    Somlyo, A.V.2
  • 35
    • 12244285281 scopus 로고    scopus 로고
    • Rho-kinase inhibition blunts renal vasoconstriction induced by distinct signaling pathways in vivo
    • Cavarape A., Endlich N., Assaloni R., Bartoli E., Steinhausen M., Parekh N., et al. Rho-kinase inhibition blunts renal vasoconstriction induced by distinct signaling pathways in vivo. J Am Soc Nephrol 14 (2003) 37-45
    • (2003) J Am Soc Nephrol , vol.14 , pp. 37-45
    • Cavarape, A.1    Endlich, N.2    Assaloni, R.3    Bartoli, E.4    Steinhausen, M.5    Parekh, N.6
  • 36
    • 0037223146 scopus 로고    scopus 로고
    • Signaling: focus on Rho in renal disease
    • Sharpe C.C., and Hendry B.M. Signaling: focus on Rho in renal disease. J Am Soc Nephrol 14 (2003) 261-264
    • (2003) J Am Soc Nephrol , vol.14 , pp. 261-264
    • Sharpe, C.C.1    Hendry, B.M.2
  • 37
    • 0030656619 scopus 로고    scopus 로고
    • Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension
    • Uehata M., Ishizaki T., Satoh H., Ono T., Kawahara T., Morishita T., et al. Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension. Nature 389 (1997) 990-994
    • (1997) Nature , vol.389 , pp. 990-994
    • Uehata, M.1    Ishizaki, T.2    Satoh, H.3    Ono, T.4    Kawahara, T.5    Morishita, T.6
  • 38
    • 33745285003 scopus 로고    scopus 로고
    • Increased RhoA/Rho-kinase signaling mediates spontaneous tone in aorta from angiotensin II-induced hypertensive rats
    • Jin L., Ying Z., Hilgers R.H., Yin J., Zhao X., Imig J.D., et al. Increased RhoA/Rho-kinase signaling mediates spontaneous tone in aorta from angiotensin II-induced hypertensive rats. J Pharmacol Exp Ther 318 (2006) 288-295
    • (2006) J Pharmacol Exp Ther , vol.318 , pp. 288-295
    • Jin, L.1    Ying, Z.2    Hilgers, R.H.3    Yin, J.4    Zhao, X.5    Imig, J.D.6
  • 39
    • 15744369474 scopus 로고    scopus 로고
    • Enhanced activation of RhoA by angiotensin II in SHR preglomerular microvascular smooth muscle cells
    • Jackson E.K., Andresen B.T., Seasholtz T.M., Zhu C., and Romero G.G. Enhanced activation of RhoA by angiotensin II in SHR preglomerular microvascular smooth muscle cells. J Cardiovasc Pharmacol 45 (2005) 283-285
    • (2005) J Cardiovasc Pharmacol , vol.45 , pp. 283-285
    • Jackson, E.K.1    Andresen, B.T.2    Seasholtz, T.M.3    Zhu, C.4    Romero, G.G.5
  • 40
    • 0013198310 scopus 로고    scopus 로고
    • Improved erectile function after Rho-kinase inhibition in a rat castrate model of erectile dysfunction
    • Wingard C.J., Johnson J.A., Holmes A., and Prikosh A. Improved erectile function after Rho-kinase inhibition in a rat castrate model of erectile dysfunction. Am J Physiol Regul Integr Comp Physiol 284 (2003) R1572-R1579
    • (2003) Am J Physiol Regul Integr Comp Physiol , vol.284
    • Wingard, C.J.1    Johnson, J.A.2    Holmes, A.3    Prikosh, A.4
  • 41
    • 0030791848 scopus 로고    scopus 로고
    • Decline in renal hemodynamic function in aging SHR: role of androgens
    • Reckelhoff J.F., Zhang H., and Granger J.P. Decline in renal hemodynamic function in aging SHR: role of androgens. Hypertension 30 (1997) 677-681
    • (1997) Hypertension , vol.30 , pp. 677-681
    • Reckelhoff, J.F.1    Zhang, H.2    Granger, J.P.3
  • 43
    • 4344704302 scopus 로고    scopus 로고
    • Fasudil, a Rho-kinase inhibitor, attenuates glomerulosclerosis in Dahl salt-sensitive rats
    • Nishikimi T., Akimoto K., Wang X., Mori Y., Tadokoro K., Ishikawa Y., et al. Fasudil, a Rho-kinase inhibitor, attenuates glomerulosclerosis in Dahl salt-sensitive rats. J Hypertens 22 (2004) 1787-1796
    • (2004) J Hypertens , vol.22 , pp. 1787-1796
    • Nishikimi, T.1    Akimoto, K.2    Wang, X.3    Mori, Y.4    Tadokoro, K.5    Ishikawa, Y.6
  • 44
    • 33744996300 scopus 로고    scopus 로고
    • Long-term administration of Rho-kinase inhibitor ameliorates renal damage in malignant hypertensive rats
    • Ishikawa Y., Nishikimi T., Akimoto K., Ishimura K., Ono H., and Matsuoka H. Long-term administration of Rho-kinase inhibitor ameliorates renal damage in malignant hypertensive rats. Hypertension 47 (2006) 1075-1083
    • (2006) Hypertension , vol.47 , pp. 1075-1083
    • Ishikawa, Y.1    Nishikimi, T.2    Akimoto, K.3    Ishimura, K.4    Ono, H.5    Matsuoka, H.6
  • 45
    • 33746539611 scopus 로고    scopus 로고
    • Involvements of Rho-kinase and TGF-beta pathways in aldosterone-induced renal injury
    • Sun G.P., Kohno M., Guo P., Nagai Y., Miyata K., Fan Y.Y., et al. Involvements of Rho-kinase and TGF-beta pathways in aldosterone-induced renal injury. J Am Soc Nephrol 17 (2006) 2193-2201
    • (2006) J Am Soc Nephrol , vol.17 , pp. 2193-2201
    • Sun, G.P.1    Kohno, M.2    Guo, P.3    Nagai, Y.4    Miyata, K.5    Fan, Y.Y.6
  • 46
    • 12744255285 scopus 로고    scopus 로고
    • Therapeutic potential of Rho-kinase inhibitors in cardiovascular diseases
    • Hirooka Y., and Shimokawa H. Therapeutic potential of Rho-kinase inhibitors in cardiovascular diseases. Am J Cardiovasc Drugs 5 (2005) 31-39
    • (2005) Am J Cardiovasc Drugs , vol.5 , pp. 31-39
    • Hirooka, Y.1    Shimokawa, H.2


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