메뉴 건너뛰기




Volumn 155, Issue 7, 2014, Pages 2456-2466

Intermittent fasting induces hypothalamic modifications resulting in low feeding efficiency, low body mass and overeating

Author keywords

[No Author keywords available]

Indexed keywords

AGOUTI RELATED PROTEIN; LIPID; NEUROPEPTIDE Y;

EID: 84903289573     PISSN: 00137227     EISSN: 19457170     Source Type: Journal    
DOI: 10.1210/en.2013-2057     Document Type: Article
Times cited : (38)

References (63)
  • 1
    • 80052265096 scopus 로고    scopus 로고
    • Commonly adopted caloric restriction protocols often involve malnutrition
    • Cerqueira FM, Kowaltowski AJ. Commonly adopted caloric restriction protocols often involve malnutrition. Ageing Res Rev. 2010;7:552-560.
    • (2010) Ageing Res Rev , vol.7 , pp. 552-560
    • Cerqueira, F.M.1    Kowaltowski, A.J.2
  • 2
    • 0000354470 scopus 로고
    • Apparent prolongation of the life span of rats by intermittent fasting
    • Carlson AJ, Hoelzel F. Apparent prolongation of the life span of rats by intermittent fasting. J Nutr. 1946;31:363-375.
    • (1946) J Nutr , vol.31 , pp. 363-375
    • Carlson, A.J.1    Hoelzel, F.2
  • 3
    • 48349144852 scopus 로고    scopus 로고
    • Resveratrol delays age-related deterioration and mimics transcriptional aspects of dietary restriction without extending life span
    • Pearson KJ, Baur JA, Lewis KN, et al. Resveratrol delays age-related deterioration and mimics transcriptional aspects of dietary restriction without extending life span. Cell Metab. 2008;8:157-168.
    • (2008) Cell Metab , vol.8 , pp. 157-168
    • Pearson, K.J.1    Baur, J.A.2    Lewis, K.N.3
  • 4
    • 0037639031 scopus 로고    scopus 로고
    • Intermittent food deprivation improves cardiovascular and neuroendocrine responses to stress in rats
    • Wan R, Camandola S, Mattson MP. Intermittent food deprivation improves cardiovascular and neuroendocrine responses to stress in rats. J Nutr. 2003;133:1921-1929. (Pubitemid 36666536)
    • (2003) Journal of Nutrition , vol.133 , Issue.6 , pp. 1921-1929
    • Wan, R.1    Camandola, S.2    Mattson, M.P.3
  • 6
    • 33947264635 scopus 로고    scopus 로고
    • Intermittent fasting and caloric restriction ameliorate age-related behavioral deficits in the triple-transgenic mouse model of Alzheimer's disease
    • DOI 10.1016/j.nbd.2006.12.019, PII S0969996106003251
    • Halagappa VK, Guo Z, Pearson M, et al. Intermittent fasting and caloric restriction ameliorate age-related behavioral deficits in the triple-transgenic mouse model of Alzheimer's disease. Neurobiol Dis. 2007;26:212-220. (Pubitemid 46436499)
    • (2007) Neurobiology of Disease , vol.26 , Issue.1 , pp. 212-220
    • Halagappa, V.K.M.1    Guo, Z.2    Pearson, M.3    Matsuoka, Y.4    Cutler, R.G.5    LaFerla, F.M.6    Mattson, M.P.7
  • 8
    • 80052270970 scopus 로고    scopus 로고
    • Long-term intermittent feeding, but not caloric restriction, leads to redox imbalance, insulin receptor nitration and glucose intolerance
    • Cerqueira FM, Cunha FM, Caldeira da Silva CC, et al. Long-term intermittent feeding, but not caloric restriction, leads to redox imbalance, insulin receptor nitration and glucose intolerance. Free Radic Biol Med. 2011;51:1454-1460.
    • (2011) Free Radic Biol Med , vol.51 , pp. 1454-1460
    • Cerqueira, F.M.1    Cunha, F.M.2    Caldeira Da Silva, C.C.3
  • 9
    • 33745657642 scopus 로고    scopus 로고
    • The diet restriction paradigm: A brief review of the effects of every-other-day feeding
    • DOI 10.1007/s11357-005-3286-2
    • Anson RM, Jones B, de Cabo R. The diet restriction paradigm: a brief review of the effects of every-other-day feeding. Age (Dordr). 2005;27:17-25. (Pubitemid 43971790)
    • (2005) Age , vol.27 , Issue.1 , pp. 17-25
    • Anson, R.M.1    Jones, B.2    De Cabo, R.3
  • 10
    • 0034611678 scopus 로고    scopus 로고
    • Towards a molecular understanding of adaptive thermogenesis
    • Lowell BB, Spiegelman BM. Towards a molecular understanding of adaptive thermogenesis. Nature. 2000;404:652-660. (Pubitemid 30205070)
    • (2000) Nature , vol.404 , Issue.6778 , pp. 652-660
    • Lowell, B.B.1    Spiegelman, B.M.2
  • 12
    • 0037122766 scopus 로고    scopus 로고
    • Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase
    • DOI 10.1038/415339a
    • Minokoshi Y, Kim YB, Peroni OD, Fryer LG, Müller C, Carling D, Kahn BB. Leptin stimulates fatty-acid oxidation by activating AMP activated protein kinase. Nature. 2002;415:339-343. (Pubitemid 34087557)
    • (2002) Nature , vol.415 , Issue.6869 , pp. 339-343
    • Minokoshi, Y.1    Kim, Y.-B.2    Peroni, O.D.3    Fryer, L.G.D.4    Muller, C.5    Carling, D.6    Kahn, B.B.7
  • 13
    • 0347989317 scopus 로고    scopus 로고
    • Brown Adipose Tissue: Function and Physiological Significance
    • DOI 10.1152/physrev.00015.2003
    • Cannon B, Nedergaard J. Brown Adipose Tissue: Function and Physiological Significance. Physiol Rev. 2004;84:277-359. (Pubitemid 38054374)
    • (2004) Physiological Reviews , vol.84 , Issue.1 , pp. 277-359
    • Cannon, B.1    Nedergaard, J.2
  • 14
    • 69149095206 scopus 로고    scopus 로고
    • Leptin-mediated changes in hepatic mitochondrial metabolism, structure, and protein levels
    • Singh A, Wirtiz M, Parker N, et al. Leptin-mediated changes in hepatic mitochondrial metabolism, structure, and protein levels. PNAS. 2009;106:13100-13105.
    • (2009) PNAS , vol.106 , pp. 13100-13105
    • Singh, A.1    Wirtiz, M.2    Parker, N.3
  • 15
    • 79959449682 scopus 로고    scopus 로고
    • Central leptin activates mitochondrial function and increases heat production in skeletal muscle
    • Henry BA, Andrews ZB, Rao A, Clarke IJ. Central leptin activates mitochondrial function and increases heat production in skeletal muscle. Endocrinology. 2011;152:2609-2618.
    • (2011) Endocrinology , vol.152 , pp. 2609-2618
    • Henry, B.A.1    Andrews, Z.B.2    Rao, A.3    Clarke, I.J.4
  • 16
    • 79961028580 scopus 로고    scopus 로고
    • Using brown adipose tissue to treat obesity - The central issue
    • Whittle AJ, López M, Vidal-Puig A. Using brown adipose tissue to treat obesity - the central issue. Trends Mol Med. 2011;17:405-411.
    • (2011) Trends Mol Med , vol.17 , pp. 405-411
    • Whittle, A.J.1    López, M.2    Vidal-Puig, A.3
  • 17
    • 79955701330 scopus 로고    scopus 로고
    • Leptin and the regulation of body weight
    • Friedman JM. Leptin and the regulation of body weight. Keio J Med. 2010;60:1-9.
    • (2010) Keio J Med , vol.60 , pp. 1-9
    • Friedman, J.M.1
  • 18
    • 0032130554 scopus 로고    scopus 로고
    • Coexpression of Agrp and NPY in fasting-activated hypothalamic neurons
    • Hahn TM, Breininger JF, Baskin DG, Schwartz MW. Coexpression of Agrp and NPY in fasting-activated hypothalamic neurons. Nat Neurosci. 1998;1:271-272. (Pubitemid 128652670)
    • (1998) Nature Neuroscience , vol.1 , Issue.4 , pp. 271-272
    • Hahn, T.M.1    Breininger, J.F.2    Baskin, D.G.3    Schwartz, M.W.4
  • 19
    • 0028139089 scopus 로고
    • Positional cloning of the mouse obese gene and its human homologue
    • DOI 10.1038/372425a0
    • Zhang Y, Proenca R, Maffei M, Barone M, Leopold L, Friedman JM. Positional clone of mouse obese gene and its human homologue. Nature. 1994;372:425-432. (Pubitemid 24365442)
    • (1994) Nature , vol.372 , Issue.6505 , pp. 425-432
    • Zhang, Y.1    Proenca, R.2    Maffei, M.3    Barone, M.4    Leopold, L.5    Friedman, J.M.6
  • 21
    • 84856450553 scopus 로고    scopus 로고
    • Altered hypothalamic function in diet-induced obesity
    • Velloso LA, Schwartz MW. Altered hypothalamic function in diet-induced obesity. Int J Obes. 2011;35:1455-1465.
    • (2011) Int J Obes , vol.35 , pp. 1455-1465
    • Velloso, L.A.1    Schwartz, M.W.2
  • 22
    • 84864710223 scopus 로고    scopus 로고
    • Selective insulin and leptin resistance in metabolic disorders
    • Könner C, Brüning JC. Selective insulin and leptin resistance in metabolic disorders. Cell Metab. 2012;16:144-152.
    • (2012) Cell Metab , vol.16 , pp. 144-152
    • Könner, C.1    Brüning, J.C.2
  • 23
    • 0027346107 scopus 로고
    • Separation and analysis of phospholipids by thin layer chromatography
    • Graham JM, Higgins JA, eds. Methods molecular biology. Totowa: Humana Press Inc
    • Cartwright, IJ. 1993 Separation and analysis of phospholipids by thin layer chromatography. In: Graham JM, Higgins JA, eds. Methods molecular biology. Biomembrane protocols. Vol. 19. Totowa: Humana Press Inc; 153-167.
    • (1993) Biomembrane Protocols , vol.19 , pp. 153-167
    • Cartwright, I.J.1
  • 24
  • 25
    • 33644613629 scopus 로고    scopus 로고
    • Signals from intra-abdominal fat modulate insulin and leptin sensitivity through different mechanisms: Neuronal involvement in food-intake regulation
    • Yamada T, Katagiri H, Ishigaki Y, et al. Signals from intra-abdominal fat modulate insulin and leptin sensitivity through different mechanisms: neuronal involvement in food-intake regulation. Cell Metab. 2006;3:223-229.
    • (2006) Cell Metab , vol.3 , pp. 223-229
    • Yamada, T.1    Katagiri, H.2    Ishigaki, Y.3
  • 26
  • 27
    • 77957010982 scopus 로고
    • Citrate synthase
    • Srere PA. Citrate synthase. Methods Enzymol. 1969;13:3-11.
    • (1969) Methods Enzymol , vol.13 , pp. 3-11
    • Srere, P.A.1
  • 28
    • 63349087445 scopus 로고    scopus 로고
    • Tissue-, substrate-, and site-specific characteristics of mitochondrial reactive oxygen species generation
    • Tahara EB, Navarete FD, Kowaltowski AJ. Tissue-, substrate-, and site-specific characteristics of mitochondrial reactive oxygen species generation. Free Radic Biol Med. 2009;46:1283-1297.
    • (2009) Free Radic Biol Med , vol.46 , pp. 1283-1297
    • Tahara, E.B.1    Navarete, F.D.2    Kowaltowski, A.J.3
  • 31
    • 0023878876 scopus 로고
    • Estimation of energy expenditure, net carbohydrate utilization, and net fat oxidation and synthesis by indirect calorimetry: Evaluation of errors with special reference to the detailed composition of fuels
    • Livesey G, Elia M. Estimation of energy expenditure, net carbohydrate utilization, and net fat oxidation and synthesis by indirect calorimetry: evaluation of errors with special reference to the detailed composition of fuels. Am J Clin Nutri. 1988;47:608-628.
    • (1988) Am J Clin Nutri , vol.47 , pp. 608-628
    • Livesey, G.1    Elia, M.2
  • 32
    • 0028095282 scopus 로고
    • Practical aspects of indirect calorimetry in laboratory animals
    • DOI 10.1016/0149-7634(94)90056-6
    • Even PC, Mokhtarian A, Pele A. Practical aspects of indirect calorimetry in laboratory. Neurosci Biobehav Rev. 1994;18:435-447. (Pubitemid 24258715)
    • (1994) Neuroscience and Biobehavioral Reviews , vol.18 , Issue.3 , pp. 435-447
    • Even, P.C.1    Mokhtarian, A.2    Pele, A.3
  • 33
    • 0030466371 scopus 로고    scopus 로고
    • The retardation of aging by caloric restriction: Studies in rodents and primates
    • Weindruch R. The retardation of aging by caloric restriction: Studies in rodents and primates. Toxicol Pathol. 1996;24:742-745.
    • (1996) Toxicol Pathol , vol.24 , pp. 742-745
    • Weindruch, R.1
  • 34
    • 0000567961 scopus 로고    scopus 로고
    • Caloric restriction reverses hepatic insulin resistance in aging rats by decreasing visceral fat
    • Barzilai N, Banerjee S, Hawkins M, Chen W, Rossetti L. Caloric restriction reverses hepatic insulin resistance in aging rats by decreasing visceral fat. J Clin Invest. 1998;101:1353-1361. (Pubitemid 28166832)
    • (1998) Journal of Clinical Investigation , vol.101 , Issue.7 , pp. 1353-1361
    • Barzilai, N.1    Banerjee, S.2    Hawkins, M.3    Chen, W.4    Rossetti, L.5
  • 35
    • 0032558725 scopus 로고    scopus 로고
    • Leptin and the regulation of body weight in mammals
    • DOI 10.1038/27376
    • Friedman JM, Halaas JL. Leptin and the regulation of body weight in mammals. Nature. 1998;395:763-770. (Pubitemid 28485436)
    • (1998) Nature , vol.395 , Issue.6704 , pp. 763-770
    • Friedman, J.M.1    Halaas, J.L.2
  • 37
    • 0024992271 scopus 로고
    • Central effects of CRF on metabolism and energy balance
    • DOI 10.1016/S0149-7634(05)80037-5
    • Rothwell NJ. Central effects of CRF on metabolism and energy balance. Neurosci Biobehav Rev. 1990;14:263-271. (Pubitemid 20266408)
    • (1990) Neuroscience and Biobehavioral Reviews , vol.14 , Issue.3 , pp. 263-271
    • Rothwell, N.J.1
  • 38
    • 0036325531 scopus 로고    scopus 로고
    • Genetic approaches to studying energy balance: Perception and integration
    • Barsh GS, Schwartz MW. Genetic approaches to studying energy balance: perception and integration. Nat Rev Genet. 2002;3:589-600. (Pubitemid 34827133)
    • (2002) Nature Reviews Genetics , vol.3 , Issue.8 , pp. 589-600
    • Barsh, G.S.1    Schwartz, M.W.2
  • 39
    • 84862150019 scopus 로고    scopus 로고
    • Hypothalamic neuropeptides and the regulation of appetite
    • Parker JA, Bloom SR. Hypothalamic neuropeptides and the regulation of appetite. Neuropharmacology. 2012;63:18-30.
    • (2012) Neuropharmacology , vol.63 , pp. 18-30
    • Parker, J.A.1    Bloom, S.R.2
  • 41
    • 33947668326 scopus 로고    scopus 로고
    • Dietary restriction, glycolysis, hormesis and ageing
    • DOI 10.1007/s10522-006-9034-x
    • Hipkiss AR. Dietary restriction, glycolysis, hormesis and ageing. Biogerontology. 2007;8:221-224. (Pubitemid 46487989)
    • (2007) Biogerontology , vol.8 , Issue.2 , pp. 221-224
    • Hipkiss, A.R.1
  • 43
    • 72949087976 scopus 로고    scopus 로고
    • Changes in behavior and gene expression induced by caloric restriction in C57BL/6 mice
    • Yamamoto Y, Tanahashi T, Kawai T, et al. Changes in behavior and gene expression induced by caloric restriction in C57BL/6 mice. Physiol Genomics. 2009;39:227-235.
    • (2009) Physiol Genomics , vol.39 , pp. 227-235
    • Yamamoto, Y.1    Tanahashi, T.2    Kawai, T.3
  • 44
    • 33746308184 scopus 로고    scopus 로고
    • Chapter 12: The TRH neuron: A hypothalamic integrator of energy metabolism
    • DOI 10.1016/S0079-6123(06)53012-2, PII S0079612306530122, Hypothalmic Integration of Energy Metabolism
    • Lechan RM, Fakete C. The TRH neuron: a hypothalamic integrator of energy metabolism. Prog Brain Res. 2006;153:209-235. (Pubitemid 44107417)
    • (2006) Progress in Brain Research , vol.153 , pp. 209-235
    • Lechan, R.M.1    Fekete, C.2
  • 47
    • 0032742372 scopus 로고    scopus 로고
    • UCP2 and UCP3 rise in starved rat skeletal muscle but mitochondrial proton conductance is unchanged
    • Cadenas S, Buckingham JA, Samec S, et al. UCP2 and UCP3 rise in starved rat skeletal muscle but mitochondrial proton conductance is unchanged. FEBS Lett. 1999;462:257-260.
    • (1999) FEBS Lett , vol.462 , pp. 257-260
    • Cadenas, S.1    Buckingham, J.A.2    Samec, S.3
  • 48
    • 77953811513 scopus 로고    scopus 로고
    • Cold tolerance of UCP1-ablated mice: A skeletal muscle mitochondria switch toward lipid oxidation with marked UCP3 up-regulation not associated with increased basal, fatty acid or ROS-induced uncoupling or enhanced GDP effects
    • Shabalina IG, Hoeks J, Kramarova TV, Schrauwen P, Cannon B, Nedergaard J. Cold tolerance of UCP1-ablated mice: a skeletal muscle mitochondria switch toward lipid oxidation with marked UCP3 up-regulation not associated with increased basal, fatty acid or ROS-induced uncoupling or enhanced GDP effects. Biochim Biophys Acta. 2010;1797:968-980.
    • (2010) Biochim Biophys Acta , vol.1797 , pp. 968-980
    • Shabalina, I.G.1    Hoeks, J.2    Kramarova, T.V.3    Schrauwen, P.4    Cannon, B.5    Nedergaard, J.6
  • 51
    • 78650046347 scopus 로고    scopus 로고
    • Muscle wasting in aged, sarcopenic rats is associated with enhanced activity of the ubiquitin proteasome pathway
    • Altun M, Besche HC, Overkleeft HS, et al. Muscle wasting in aged, sarcopenic rats is associated with enhanced activity of the ubiquitin proteasome pathway. J Biol Chem. 2010;285:39597-39608.
    • (2010) J Biol Chem , vol.285 , pp. 39597-39608
    • Altun, M.1    Besche, H.C.2    Overkleeft, H.S.3
  • 52
    • 84863181604 scopus 로고    scopus 로고
    • Decreased proteasomal activity causes age-related phenotypes and promotes the development of metabolic abnormalities
    • Tomaru U, Takahashi S, Ishizu A, et al. Decreased proteasomal activity causes age-related phenotypes and promotes the development of metabolic abnormalities. Am J Pathol. 2012;180:963-972.
    • (2012) Am J Pathol , vol.180 , pp. 963-972
    • Tomaru, U.1    Takahashi, S.2    Ishizu, A.3
  • 53
    • 0022993093 scopus 로고
    • Starvation-induced changes in metabolic rate, blood flow, and regional energy expenditure in rats
    • Swy M, Do F. Starvation-induced changes in metabolic rate, blood flow, and regional energy expenditure in rats. Can J Physiol Pharmacol. 1986;64:1252-1258.
    • (1986) Can J Physiol Pharmacol , vol.64 , pp. 1252-1258
    • Swy, M.1    Do, F.2
  • 54
    • 0024423544 scopus 로고
    • Fuel selection and carbon flux during the starved-to-fed transition
    • Sugden MC, Holness MJ, Palmer TN. Fuel selection and carbon flux during the starved-to-fed transition. Biochem J. 1989;263:313-323. (Pubitemid 19254133)
    • (1989) Biochemical Journal , vol.263 , Issue.2 , pp. 313-323
    • Sugden, M.C.1    Holness, M.J.2    Palmer, T.N.3
  • 55
    • 33750110683 scopus 로고    scopus 로고
    • Fuel metabolism in starvation
    • Cahill GF. Fuel metabolism in starvation. Annu Rev Nutr. 2006;26:1-22.
    • (2006) Annu Rev Nutr , vol.26 , pp. 1-22
    • Cahill, G.F.1
  • 56
    • 77950908035 scopus 로고    scopus 로고
    • "Control" laboratory rodents are metabolically morbid: Why it matters
    • Martin B, Jia S, Maudsleyb S, Mattson MP. "Control" laboratory rodents are metabolically morbid: Why it matters. Proc Natl Acad Sci USA. 2010;107:6127-6133.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 6127-6133
    • Martin, B.1    Jia, S.2    Maudsleyb, S.3    Mattson, M.P.4
  • 58
    • 84875883939 scopus 로고    scopus 로고
    • Tanycytic VEGF-A boosts blood-hypothalamus barrier plasticity and access of metabolic signals to the arcuate nucleus in response to fasting
    • Langlet F, Levin BE, Luquet S, et al. Tanycytic VEGF-A boosts blood-hypothalamus barrier plasticity and access of metabolic signals to the arcuate nucleus in response to fasting. Cell Metab. 2013;17:607-617.
    • (2013) Cell Metab , vol.17 , pp. 607-617
    • Langlet, F.1    Levin, B.E.2    Luquet, S.3
  • 59
    • 0041820107 scopus 로고    scopus 로고
    • The hepatic vagus mediates fat-induced inhibition of diabetic hyperphagia
    • DOI 10.2337/diabetes.52.9.2321
    • la Fleur SE, Ji H, Manalo SL, Friedman MI, Dallman MF. The hepatic vagus mediates fat-induced inhibition of diabetic hyperphagia. Diabetes. 2003;52:2321-2330. (Pubitemid 37059503)
    • (2003) Diabetes , vol.52 , Issue.9 , pp. 2321-2330
    • La, F.S.E.1    Ji, H.2    Manalo, S.L.3    Friedman, M.I.4    Dallman, M.F.5
  • 61
    • 80052922112 scopus 로고    scopus 로고
    • Hunger states switch a flip-flop memory circuit via a synaptic AMPK-dependent positive feedback loop
    • Yang Y, Atasoy D, Su HH, Sternson SM. Hunger states switch a flip-flop memory circuit via a synaptic AMPK-dependent positive feedback loop. Cell. 2011;146:992-1003.
    • (2011) Cell , vol.146 , pp. 992-1003
    • Yang, Y.1    Atasoy, D.2    Su, H.H.3    Sternson, S.M.4
  • 62
    • 0036066483 scopus 로고    scopus 로고
    • The concept of selective leptin resistance: Evidence from agouti yellow obese mice
    • Correia MLG, Haynes WG, Rahmouni K, Morgan DA, Sivitz WI, Mark AL. The concept of selective leptin resistance: Evidence from agouti yellow obese mice. Diabetes. 2002;51:439-442. (Pubitemid 34764800)
    • (2002) Diabetes , vol.51 , Issue.2 , pp. 439-442
    • Correia, M.L.G.1    Haynes, W.G.2    Rahmouni, K.3    Morgan, D.A.4    Sivitz, W.I.5    Mark, A.L.6
  • 63
    • 0036628739 scopus 로고    scopus 로고
    • Selective leptin resistance: A new concept in leptin physiology with cardiovascular implications
    • DOI 10.1097/00004872-200207000-00001
    • Mark AL, Correia MLG, Rahmounia K, Haynesa WG. Selective leptin resistance: a new concept in leptin physiology with cardiovascular implications. J Hypertens. 2002;20:1245-1250. (Pubitemid 34925659)
    • (2002) Journal of Hypertension , vol.20 , Issue.7 , pp. 1245-1250
    • Mark, A.L.1    Correia, M.L.G.2    Rahmouni, K.3    Haynes, W.G.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.