A Novel Nodal Enhancer Dependent on Pluripotency Factors and Smad2/3 Signaling Conditions a Regulatory Switch During Epiblast Maturation

PLoS Biology

Volumn 12, Issue 6, 2014, Pages

  Papanayotou, Costis ^a   Benhaddou, Ataaillah ^a   Camus, Anne ^a   Perea Gomez, Aitana ^a   Jouneau, Alice ^b   Mezger, Valérie ^c   Langa, Francina ^d   Ott, Sascha ^e   Sabéran Djoneidi, Délara ^a,c   Collignon, Jérôme ^a  

^a INSTITUT JACQUES MONOD   (France)

^b ECOLE NATIONALE VÉTÉRINAIRE D ALFORT   (France)

^c CNRS   (France)

^d INSTITUT PASTEUR   (France)

^e UNIVERSITY OF WARWICK   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVIN; OCTAMER TRANSCRIPTION FACTOR 4; PROTEIN NODAL; SMAD2 PROTEIN; SMAD3 PROTEIN; HOMEODOMAIN PROTEIN; INHIBIN; INHIBIN BETA A SUBUNIT; NANOG PROTEIN, MOUSE; NODAL PROTEIN, MOUSE; POU5F1 PROTEIN, MOUSE; SMAD2 PROTEIN, MOUSE; SMAD3 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; DNA STRUCTURE; ECTODERM; EMBRYO; EMBRYO DEVELOPMENT; EMBRYONIC STEM CELL; ENHANCER REGION; FEMALE; GENE DELETION; GENE EXPRESSION; GENE LOCUS; GENE MUTATION; HIGHLY BOUND ELEMENT; IN VITRO STUDY; MOUSE; NODAL GENE; NONHUMAN; PLURIPOTENT STEM CELL; REPORTER GENE; SIGNAL TRANSDUCTION; TRANSGENE; ANIMAL; CELL LINE; CYTOLOGY; GENE EXPRESSION REGULATION; GERM LAYER; METABOLISM; PHYSIOLOGY; TRANSGENIC MOUSE;

ANIMALS; CELL DIFFERENTIATION; CELL LINE; EMBRYONIC STEM CELLS; ENHANCER ELEMENTS, GENETIC; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GERM LAYERS; HOMEODOMAIN PROTEINS; INHIBIN-BETA SUBUNITS; MICE; MICE, TRANSGENIC; NODAL PROTEIN; OCTAMER TRANSCRIPTION FACTOR-3; PLURIPOTENT STEM CELLS; SMAD2 PROTEIN; SMAD3 PROTEIN;

EID: 84903289273     PISSN: 15449173     EISSN: 15457885     Source Type: Journal    
DOI: 10.1371/journal.pbio.1001890     Document Type: Article

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