메뉴 건너뛰기




Volumn 13, Issue 12, 1999, Pages 1575-1588

Asymmetric and node-specific nodal expression patterns are controlled by two distinct cis-acting regulatory elements

Author keywords

Axis formation; Left right asymmetry; Mouse development; Nodal; TGF signaling

Indexed keywords

TRANSFORMING GROWTH FACTOR BETA;

EID: 0033564874     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: 10.1101/gad.13.12.1575     Document Type: Article
Times cited : (151)

References (71)
  • 1
    • 0345718716 scopus 로고    scopus 로고
    • Left-right asymmetric expression of nodal is controlled by a left side-specific enhancer
    • this issue
    • Adachi, H., Y. Saijoh, K. Mochida, K. Oishi, and H. Hamada. 1999. Left-right asymmetric expression of nodal is controlled by a left side-specific enhancer. Genes & Dev. (this issue).
    • (1999) Genes & Dev.
    • Adachi, H.1    Saijoh, Y.2    Mochida, K.3    Oishi, K.4    Hamada, H.5
  • 2
    • 0028169992 scopus 로고
    • HNF-3β is essential for node and notochord formation in mouse development
    • Ang, S.-L. and J. Rossant. 1994. HNF-3β is essential for node and notochord formation in mouse development. Cell 78: 561-574.
    • (1994) Cell , vol.78 , pp. 561-574
    • Ang, S.-L.1    Rossant, J.2
  • 3
    • 0027425136 scopus 로고
    • The formation and maintenance of the definitive endoderm lineage in the mouse: Involvement of the HNF3/fork head proteins
    • Ang, S.-L., A. Weirda, D. Wong, K.A. Stevens, S. Cascko, J. Rossant, and K.S. Zaret. 1993. The formation and maintenance of the definitive endoderm lineage in the mouse: Involvement of the HNF3/fork head proteins. Development 119: 1301-1315.
    • (1993) Development , vol.119 , pp. 1301-1315
    • Ang, S.-L.1    Weirda, A.2    Wong, D.3    Stevens, K.A.4    Cascko, S.5    Rossant, J.6    Zaret, K.S.7
  • 4
    • 0028205003 scopus 로고
    • Induction of a second neural axis by the mouse node
    • Beddington, R.S.P. 1994. Induction of a second neural axis by the mouse node. Development 120: 613-620.
    • (1994) Development , vol.120 , pp. 613-620
    • Beddington, R.S.P.1
  • 5
    • 0024517749 scopus 로고
    • An assessment of the developmental potential of embryonic stem cells in the midgestation embyro
    • Beddington, R.S.P. and E.J. Robertson. 1989. An assessment of the developmental potential of embryonic stem cells in the midgestation embyro. Development 105: 733-737.
    • (1989) Development , vol.105 , pp. 733-737
    • Beddington, R.S.P.1    Robertson, E.J.2
  • 6
    • 0032127227 scopus 로고    scopus 로고
    • Anterior patterning in the mouse
    • _. 1998. Anterior patterning in the mouse. Trends Genet. 14: 277-284.
    • (1998) Trends Genet. , vol.14 , pp. 277-284
  • 7
    • 0033593571 scopus 로고    scopus 로고
    • Axis development and early asymmetry in mammals
    • _. 1999. Axis development and early asymmetry in mammals. Cell 96: 195-209.
    • (1999) Cell , vol.96 , pp. 195-209
  • 8
    • 0030218077 scopus 로고    scopus 로고
    • A new mouse member of the Wnt gene family, mWnt-8, is expressed during early embryogenesis and is ectopically induced by retinoic acid
    • Bouillet, P., M. Oulad-Abdelghani, S.J. Ward, S. Bronner, P. Chambon, and P. Dolle. 1996. A new mouse member of the Wnt gene family, mWnt-8, is expressed during early embryogenesis and is ectopically induced by retinoic acid. Mech. Dev. 58: 141-152.
    • (1996) Mech. Dev. , vol.58 , pp. 141-152
    • Bouillet, P.1    Oulad-Abdelghani, M.2    Ward, S.J.3    Bronner, S.4    Chambon, P.5    Dolle, P.6
  • 9
  • 10
    • 0029777408 scopus 로고    scopus 로고
    • Cyclopia and defective axial patterning in mice lacking Sonic Hedgehog gene function
    • Chiang, C., Y. Litingtung, E. Lee, J.L. Young, H. Westphal, and P. Beachy. 1996. Cyclopia and defective axial patterning in mice lacking Sonic Hedgehog gene function. Nature 383: 407-413.
    • (1996) Nature , vol.383 , pp. 407-413
    • Chiang, C.1    Litingtung, Y.2    Lee, E.3    Young, J.L.4    Westphal, H.5    Beachy, P.6
  • 11
    • 0029993646 scopus 로고    scopus 로고
    • Relationship between asymmetric nodal expression and the direction of embryonic turning
    • Collignon, J., I. Varlet, and E.J. Robertson. 1996. Relationship between asymmetric nodal expression and the direction of embryonic turning. Nature 381: 155-158.
    • (1996) Nature , vol.381 , pp. 155-158
    • Collignon, J.1    Varlet, I.2    Robertson, E.J.3
  • 12
    • 0025810391 scopus 로고
    • A novel retrovirally-induced embryonic lethal mutation in the mouse; assessment of the developmental fate of ES cells homozygous for the 413.d proviral integration
    • Conlon, F.L., K.S. Barth, and E.J. Robertson. 1991. A novel retrovirally-induced embryonic lethal mutation in the mouse; assessment of the developmental fate of ES cells homozygous for the 413.d proviral integration. Development 111: 969-981.
    • (1991) Development , vol.111 , pp. 969-981
    • Conlon, F.L.1    Barth, K.S.2    Robertson, E.J.3
  • 13
    • 0028180752 scopus 로고
    • A primary requirement for nodal in the formation and maintenance of the primitive streak in the mouse
    • Conlon, F.L., K.M. Lyons, N. Takaesu, K.S. Barth, A. Kispert, B. Herrmann, and E.J. Robertson. 1994. A primary requirement for nodal in the formation and maintenance of the primitive streak in the mouse. Development 120: 1919-1928.
    • (1994) Development , vol.120 , pp. 1919-1928
    • Conlon, F.L.1    Lyons, K.M.2    Takaesu, N.3    Barth, K.S.4    Kispert, A.5    Herrmann, B.6    Robertson, E.J.7
  • 14
    • 0031594949 scopus 로고    scopus 로고
    • The transcription factor HNF3β is required in the visceral endoderm for normal primitive streak morphogensis
    • Dufort, D., L. Schwartz, K. Harpal, and J. Rossant. 1998. The transcription factor HNF3β is required in the visceral endoderm for normal primitive streak morphogensis. Development 125: 3015-3025.
    • (1998) Development , vol.125 , pp. 3015-3025
    • Dufort, D.1    Schwartz, L.2    Harpal, K.3    Rossant, J.4
  • 15
    • 0028093078 scopus 로고
    • Cis-acting regulatory sequences governing Wnt-1 expression in the developing mouse CNS
    • Echelard, Y., G. Vassileva, and A. P. McMahon. 1994. Cis-acting regulatory sequences governing Wnt-1 expression in the developing mouse CNS. Development 120: 2213-2224.
    • (1994) Development , vol.120 , pp. 2213-2224
    • Echelard, Y.1    Vassileva, G.2    McMahon, A.P.3
  • 16
    • 0032915095 scopus 로고    scopus 로고
    • Regionalization of Sonic hedgehog transcription along the anteroposterior axis of the mouse central nervous system is regulated by Hnf3-dependent and -independent mechanisms
    • Epstein, D.J., A.P. McMahon, and A. Joyner. 1999. Regionalization of Sonic hedgehog transcription along the anteroposterior axis of the mouse central nervous system is regulated by Hnf3-dependent and -independent mechanisms. Development 126: 281-292.
    • (1999) Development , vol.126 , pp. 281-292
    • Epstein, D.J.1    McMahon, A.P.2    Joyner, A.3
  • 19
    • 0031048344 scopus 로고    scopus 로고
    • Direct neural induction and selective inhibition of mesoderm and epidermis inducers by Xnr3
    • Hansen, C.S., C.D. Marion, K. Steele, S. George, and W.C. Smith. 1997. Direct neural induction and selective inhibition of mesoderm and epidermis inducers by Xnr3. Development 124: 483-492.
    • (1997) Development , vol.124 , pp. 483-492
    • Hansen, C.S.1    Marion, C.D.2    Steele, K.3    George, S.4    Smith, W.C.5
  • 20
    • 0032493873 scopus 로고    scopus 로고
    • Links in the left/right axial pathway
    • Harvey, R.P. 1998. Links in the left/right axial pathway. Cell 94: 273-276.
    • (1998) Cell , vol.94 , pp. 273-276
    • Harvey, R.P.1
  • 23
    • 77957211015 scopus 로고
    • Visceral inversion and associated anomalies in the mouse
    • Hummel, K.P. and D.B. Chapman. 1959. Visceral inversion and associated anomalies in the mouse. J. Hered. 50: 9-23.
    • (1959) J. Hered. , vol.50 , pp. 9-23
    • Hummel, K.P.1    Chapman, D.B.2
  • 24
    • 0031051863 scopus 로고    scopus 로고
    • Control of vertebrate left-right asymmetry by a snail-related zinc finger gene
    • Isaac, A., M.G. Sargent, and J. Cooke. 1997. Control of vertebrate left-right asymmetry by a snail-related zinc finger gene. Science 275: 1301-1304.
    • (1997) Science , vol.275 , pp. 1301-1304
    • Isaac, A.1    Sargent, M.G.2    Cooke, J.3
  • 25
    • 0028787260 scopus 로고
    • Nodal-related signals induce axial mesoderm and dorsalize mesoderm during gastrulation
    • Jones, C.M., M.R. Kuehn, B.L.M. Hogan, J.C. Smith, and C.V.E. Wright. 1995. Nodal-related signals induce axial mesoderm and dorsalize mesoderm during gastrulation. Development 121: 3651-3662.
    • (1995) Development , vol.121 , pp. 3651-3662
    • Jones, C.M.1    Kuehn, M.R.2    Hogan, B.L.M.3    Smith, J.C.4    Wright, C.V.E.5
  • 26
    • 0031569878 scopus 로고    scopus 로고
    • Xnr4: A Xenopus nodal-related gene expressed in the Spemann organizer
    • Joseph, E.M. and D.A. Melton. 1997. Xnr4: A Xenopus nodal-related gene expressed in the Spemann organizer. Dev. Biol. 184: 367-372.
    • (1997) Dev. Biol. , vol.184 , pp. 367-372
    • Joseph, E.M.1    Melton, D.A.2
  • 27
    • 0032432959 scopus 로고    scopus 로고
    • The role of the brachyury gene in heart development and left-right specificiation in the mouse
    • King, T., R.S.P. Beddington, and N.A. Brown. 1999. The role of the brachyury gene in heart development and left-right specificiation in the mouse. Mech. Dev. 79: 29-37.
    • (1999) Mech. Dev. , vol.79 , pp. 29-37
    • King, T.1    Beddington, R.S.P.2    Brown, N.A.3
  • 28
    • 0029857502 scopus 로고    scopus 로고
    • Proteoglycans are required for maintenance of Wnt-11 expression in the ureter tips
    • Kispert, A., S. Vainio, L. Shen, D.H. Rowitch, and A.P. McMahon. 1996. Proteoglycans are required for maintenance of Wnt-11 expression in the ureter tips. Development 122: 3627-3637.
    • (1996) Development , vol.122 , pp. 3627-3637
    • Kispert, A.1    Vainio, S.2    Shen, L.3    Rowitch, D.H.4    McMahon, A.P.5
  • 29
    • 0029089617 scopus 로고
    • A molecular pathway determining left-right asymmetry in chick embryogenesis
    • Levin, M., R.L. Johnson, C.D. Stern, M. Kuehn, and C. Tabin. 1995. A molecular pathway determining left-right asymmetry in chick embryogenesis. Cell 82: 803-814.
    • (1995) Cell , vol.82 , pp. 803-814
    • Levin, M.1    Johnson, R.L.2    Stern, C.D.3    Kuehn, M.4    Tabin, C.5
  • 30
    • 0031238780 scopus 로고    scopus 로고
    • Left/right signals and the independent regulation of different aspects of situs in the chick embryo
    • Levin, M., S. Pagan, D. Roberts, J. Cooke, M. Kuehn, and C. Tabin. 1997. Left/right signals and the independent regulation of different aspects of situs in the chick embryo. Dev. Biol. 189: 57-67.
    • (1997) Dev. Biol. , vol.189 , pp. 57-67
    • Levin, M.1    Pagan, S.2    Roberts, D.3    Cooke, J.4    Kuehn, M.5    Tabin, C.6
  • 31
    • 0032493897 scopus 로고    scopus 로고
    • The transcription factor pitx2 mediates situs-specific morphogenesis in response to left-right asymmetric signals
    • Logan, M., S.M. Pagan-Westphal, D.M. Smith, L. Paganessi, and C.J. Tabin. 1998. The transcription factor Pitx2 mediates situs-specific morphogenesis in response to left-right asymmetric signals. Cell 94: 307-317.
    • (1998) Cell , vol.94 , pp. 307-317
    • Logan, M.1    Pagan-Westphal, S.M.2    Smith, D.M.3    Paganessi, L.4    Tabin, C.J.5
  • 32
    • 0030907502 scopus 로고    scopus 로고
    • Left-right asymmetry of a nodal-related gene is regulated by dorsoanterior midline structures during Xenopus development
    • Lohr, J.L., M.C. Danos, and H.J. Yost. 1997. Left-right asymmetry of a nodal-related gene is regulated by dorsoanterior midline structures during Xenopus development. Development 124: 1465-1472.
    • (1997) Development , vol.124 , pp. 1465-1472
    • Lohr, J.L.1    Danos, M.C.2    Yost, H.J.3
  • 34
    • 0029809261 scopus 로고    scopus 로고
    • A Xenopus nodal-related gene that acts in synergy with noggin to induce complete secondary axis and notochord formation
    • Lustig, K.D., K. Kroll, E. Sun, R. Ramos, H. Elmendorf, and M.W. Kirschner. 1996. A Xenopus nodal-related gene that acts in synergy with noggin to induce complete secondary axis and notochord formation. Development 122: 3275-3282.
    • (1996) Development , vol.122 , pp. 3275-3282
    • Lustig, K.D.1    Kroll, K.2    Sun, E.3    Ramos, R.4    Elmendorf, H.5    Kirschner, M.W.6
  • 35
    • 0030604542 scopus 로고    scopus 로고
    • TGFβ signaling: Receptors, transducers, and Mad proteins
    • Massagué, J. 1996. TGFβ signaling: Receptors, transducers, and Mad proteins. Cell 85: 947-950.
    • (1996) Cell , vol.85 , pp. 947-950
    • Massagué, J.1
  • 36
    • 0031685620 scopus 로고    scopus 로고
    • TGFβ signal transduction
    • _. 1998. TGFβ signal transduction. Annu. Rev. Biochem. 67: 753-791.
    • (1998) Annu. Rev. Biochem. , vol.67 , pp. 753-791
  • 37
    • 18744425721 scopus 로고    scopus 로고
    • LEF-1/TCF proteins mediate wnt-inducible transcription from the Xenopus nodal-related 3 promoter
    • McKendry, R., S.C. Hsu, R.M. Harland, and R. Grosschedl. 1997. LEF-1/TCF proteins mediate wnt-inducible transcription from the Xenopus nodal-related 3 promoter. Dev. Biol. 192: 420-431.
    • (1997) Dev. Biol. , vol.192 , pp. 420-431
    • McKendry, R.1    Hsu, S.C.2    Harland, R.M.3    Grosschedl, R.4
  • 39
    • 0031196157 scopus 로고    scopus 로고
    • Two closely related left-right asymmetrically expressed genes, lefty-1 and lefty-2: Their distinct expression domains, chromosomal linkage and direct neuralizing activity in Xenopus embryos
    • Meno, C., Y. Ito, Y. Saijoh, Y. Matsuda, K. Tashiiro, S. Kuhara, and H. Hamada. 1997. Two closely related left-right asymmetrically expressed genes, lefty-1 and lefty-2: Their distinct expression domains, chromosomal linkage and direct neuralizing activity in Xenopus embryos. Genes Cells 2: 513-524.
    • (1997) Genes Cells , vol.2 , pp. 513-524
    • Meno, C.1    Ito, Y.2    Saijoh, Y.3    Matsuda, Y.4    Tashiiro, K.5    Kuhara, S.6    Hamada, H.7
  • 40
    • 0344855799 scopus 로고
    • Bmpr encodes a type I bone morphogenetic protein receptor that is essential for gastrulation during mouse embryogenesis
    • Mishina, Y., A. Suzuki, N. Ueno, and R.R. Behringer. 1995. Bmpr encodes a type I bone morphogenetic protein receptor that is essential for gastrulation during mouse embryogenesis. Genes & Dev. 6: 432-438.
    • (1995) Genes & Dev. , vol.6 , pp. 432-438
    • Mishina, Y.1    Suzuki, A.2    Ueno, N.3    Behringer, R.R.4
  • 42
    • 0027425313 scopus 로고
    • Postimplantation expression patterns indicate a role for the mouse forkhead/HNF-3 α, β and γ genes in determination of the definitive endoderm, chordamesoderm and neuroectoderm
    • Monaghan, A.P., K.H. Kaestner, E. Grau, and G. Schütz. 1993. Postimplantation expression patterns indicate a role for the mouse forkhead/HNF-3 α, β and γ genes in determination of the definitive endoderm, chordamesoderm and neuroectoderm. Development 119: 567-578.
    • (1993) Development , vol.119 , pp. 567-578
    • Monaghan, A.P.1    Kaestner, K.H.2    Grau, E.3    Schütz, G.4
  • 44
    • 0032428685 scopus 로고    scopus 로고
    • Randomization of left-right asymmetry due to loss of nodal cilia generating left-ward flow of extraembryonic fluid in mice lacking KIF3B motor protein
    • Nonaka, S., Y. Tanaka, Y. Okada, S. Takeda, A. Harada, Y. Kanai, M. Kido, and N. Hirokawa. 1998. Randomization of left-right asymmetry due to loss of nodal cilia generating left-ward flow of extraembryonic fluid in mice lacking KIF3B motor protein. Cell 95: 829-837.
    • (1998) Cell , vol.95 , pp. 829-837
    • Nonaka, S.1    Tanaka, Y.2    Okada, Y.3    Takeda, S.4    Harada, A.5    Kanai, Y.6    Kido, M.7    Hirokawa, N.8
  • 45
    • 0030837018 scopus 로고    scopus 로고
    • The signaling pathway mediated by the type IIB activin receptor controls axial patterning and lateral asymmetry in the mouse
    • Oh, S.P. and E. Li. 1997. The signaling pathway mediated by the type IIB activin receptor controls axial patterning and lateral asymmetry in the mouse. Genes & Dev. 11: 1812-1826.
    • (1997) Genes & Dev. , vol.11 , pp. 1812-1826
    • Oh, S.P.1    Li, E.2
  • 47
    • 0032493860 scopus 로고    scopus 로고
    • Pitx2 participates in the late phase of the pathway controlling left-right asymmetry
    • Piedra, M.E., J.M. Icardo, M. Albajar, J.C. Rodriguez-Rey, and M.A. Ros. 1998. Pitx2 participates in the late phase of the pathway controlling left-right asymmetry. Cell 94: 319-324.
    • (1998) Cell , vol.94 , pp. 319-324
    • Piedra, M.E.1    Icardo, J.M.2    Albajar, M.3    Rodriguez-Rey, J.C.4    Ros, M.A.5
  • 49
    • 0032544016 scopus 로고    scopus 로고
    • Cyclops encodes a nodal-related factor involved in midline signaling
    • Rebagliati, M.R., R. Toyama, P. Haffter, and I.B. Dawid. 1998a. cyclops encodes a nodal-related factor involved in midline signaling. Proc. Natl. Acad. Sci. 95: 9932-9937.
    • (1998) Proc. Natl. Acad. Sci. , vol.95 , pp. 9932-9937
    • Rebagliati, M.R.1    Toyama, R.2    Haffter, P.3    Dawid, I.B.4
  • 50
    • 0032528389 scopus 로고    scopus 로고
    • Zebrafish nodal-related genes are implicated in axial patterning and establishing left-right asymmetry
    • Rebagliati, M.R., R. Toyama, C. Fricke, P. Haffter, and I.B. Dawid. 1998b. Zebrafish nodal-related genes are implicated in axial patterning and establishing left-right asymmetry. Dev. Biol. 199: 261-272.
    • (1998) Dev. Biol. , vol.199 , pp. 261-272
    • Rebagliati, M.R.1    Toyama, R.2    Fricke, C.3    Haffter, P.4    Dawid, I.B.5
  • 51
    • 0025815198 scopus 로고
    • Glucocorticoids are required for establishment and maintenance of an alteration in chromatin structure: Induction leads to a reversible disruption of nucleosomes over an enhancer
    • Reik, A., G. Schütz, and A.F. Stewart. 1991. Glucocorticoids are required for establishment and maintenance of an alteration in chromatin structure: Induction leads to a reversible disruption of nucleosomes over an enhancer. EMBO J. 10: 2569-2576.
    • (1991) EMBO J. , vol.10 , pp. 2569-2576
    • Reik, A.1    Schütz, G.2    Stewart, A.F.3
  • 53
    • 0033082264 scopus 로고    scopus 로고
    • Distinct transcriptional regulatory mechanisms underlie left-right asymmetric expression of lefty-1 and lefty-2
    • Saijoh, Y., H. Adachi, K. Mochida, S. Ohishi, A. Hirao, and H. Hamada. 1999. Distinct transcriptional regulatory mechanisms underlie left-right asymmetric expression of lefty-1 and lefty-2. Genes & Dev. 13: 259-269.
    • (1999) Genes & Dev. , vol.13 , pp. 259-269
    • Saijoh, Y.1    Adachi, H.2    Mochida, K.3    Ohishi, S.4    Hirao, A.5    Hamada, H.6
  • 54
    • 0030869668 scopus 로고    scopus 로고
    • Functional differences among Xenopus nodal-related genes in left-right axis determination
    • Sampath, K., A.M.S. Cheng, A. Frisch, and C.V.E. Wright. 1997. Functional differences among Xenopus nodal-related genes in left-right axis determination. Development 124: 3293-3302.
    • (1997) Development , vol.124 , pp. 3293-3302
    • Sampath, K.1    Cheng, A.M.S.2    Frisch, A.3    Wright, C.V.E.4
  • 56
    • 0027318791 scopus 로고
    • Differential expression of multiple fork head related genes during gastrulation and axial pattern formation in the mouse embryo
    • Sasaki, H. and B.L.M. Hogan. 1993. Differential expression of multiple fork head related genes during gastrulation and axial pattern formation in the mouse embryo. Development 118: 47-59.
    • (1993) Development , vol.118 , pp. 47-59
    • Sasaki, H.1    Hogan, B.L.M.2
  • 57
    • 0029678251 scopus 로고    scopus 로고
    • Enhancer analysis of the mouse HNF-3β gene: Regulatory elements for node/notochord and floor plate are independent and consist of multiple sub-elements
    • _. 1996. Enhancer analysis of the mouse HNF-3β gene: Regulatory elements for node/notochord and floor plate are independent and consist of multiple sub-elements. Genes Cells 1: 59-72.
    • (1996) Genes Cells , vol.1 , pp. 59-72
  • 58
    • 0029049830 scopus 로고
    • A nodal-related gene defines a physical and functional domain within the Spemann organizer
    • Smith, W.C., R. McKendry, S. Ribisi, Jr., and R.M. Harland. 1995. A nodal-related gene defines a physical and functional domain within the Spemann organizer. Cell 82: 37-46.
    • (1995) Cell , vol.82 , pp. 37-46
    • Smith, W.C.1    McKendry, R.2    Ribisi S., Jr.3    Harland, R.M.4
  • 60
    • 0030656618 scopus 로고    scopus 로고
    • Mutation of an axonemal dynein affects left-right asymmetry in inversus viscerum mice
    • Supp, D., D. Witte, S. Potter, and M. Brueckner. 1997. Mutation of an axonemal dynein affects left-right asymmetry in inversus viscerum mice. Nature 389: 963-966.
    • (1997) Nature , vol.389 , pp. 963-966
    • Supp, D.1    Witte, D.2    Potter, S.3    Brueckner, M.4
  • 61
    • 0031464087 scopus 로고    scopus 로고
    • Mouse gastrulation: The formation of a mammalian body plan
    • Tam, P.P. and R.R. Behringer. 1997. Mouse gastrulation: The formation of a mammalian body plan. Mech. Dev. 68: 3-25.
    • (1997) Mech. Dev. , vol.68 , pp. 3-25
    • Tam, P.P.1    Behringer, R.R.2
  • 62
    • 0032943366 scopus 로고    scopus 로고
    • Antivin, a novel and divergent member of the TGFβ superfamily, negatively regulates mesoderm induction
    • Thisse, C. and B. Thisse. 1999. Antivin, a novel and divergent member of the TGFβ superfamily, negatively regulates mesoderm induction. Development 126: 229-240.
    • (1999) Development , vol.126 , pp. 229-240
    • Thisse, C.1    Thisse, B.2
  • 63
    • 0030292996 scopus 로고    scopus 로고
    • Anterior primitive endoderm may be responsible for patterning the anterior neural plate in the mouse embryo
    • Thomas, P. and R.S.P. Beddington. 1996. Anterior primitive endoderm may be responsible for patterning the anterior neural plate in the mouse embryo. Curr. Biol. 6: 1487-1496.
    • (1996) Curr. Biol. , vol.6 , pp. 1487-1496
    • Thomas, P.1    Beddington, R.S.P.2
  • 64
    • 0030932236 scopus 로고    scopus 로고
    • Nodal expression in the primitive endoderm is required for the specification of the anterior axis during mouse gastrulation
    • Varlet, I., J. Collignon, and E.J. Robertson. 1997. Nodal expression in the primitive endoderm is required for the specification of the anterior axis during mouse gastrulation. Development 122: 1033-1044.
    • (1997) Development , vol.122 , pp. 1033-1044
    • Varlet, I.1    Collignon, J.2    Robertson, E.J.3
  • 65
    • 0032549806 scopus 로고    scopus 로고
    • Smad2 signaling in extraembryonic tissues determines anterior-posterior polarity of the early mouse embryo
    • Waldrip, W.R., E.K. Bikoff, P.A. Hoodless, J.L. Wrana, and E.J. Robertson. 1998. Smad2 signaling in extraembryonic tissues determines anterior-posterior polarity of the early mouse embryo. Cell 92: 797-808.
    • (1998) Cell , vol.92 , pp. 797-808
    • Waldrip, W.R.1    Bikoff, E.K.2    Hoodless, P.A.3    Wrana, J.L.4    Robertson, E.J.5
  • 67
    • 0032529159 scopus 로고    scopus 로고
    • Smads and early developmental signaling by the TGFβ superfamily
    • Whitman, M. 1998. Smads and early developmental signaling by the TGFβ superfamily. Genes & Dev. 12: 2445-2462.
    • (1998) Genes & Dev. , vol.12 , pp. 2445-2462
    • Whitman, M.1
  • 71
    • 0027510084 scopus 로고
    • Nodal is a novel TGFβ-like gene expressed in the mouse node during gastrulation
    • Zhou, X., H. Sasaki, L. Lowe, B.L.M. Hogan, and M.R. Kuehn. 1993. Nodal is a novel TGFβ-like gene expressed in the mouse node during gastrulation. Nature 361: 543-547.
    • (1993) Nature , vol.361 , pp. 543-547
    • Zhou, X.1    Sasaki, H.2    Lowe, L.3    Hogan, B.L.M.4    Kuehn, M.R.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.