Shikonin inhibits the proliferation of human lens epithelial cells by inducing apoptosis through ROS and caspase-dependent pathway

Molecules

Volumn 19, Issue 6, 2014, Pages 7785-7797

  Huang, Wan Rong ^a   Zhang, Yue ^a   Tang, Xin ^a  

^a TIANJIN MEDICAL UNIVERSITY   (China)

Author keywords

Apoptosis; Caspase dependent pathway; Human lens epithelial cells; Posterior capsular opacification

Indexed keywords

CASPASE 3; CASPASE 7; CASPASE 9; CASPASE INHIBITOR; HERBACEOUS AGENT; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; NAPHTHOQUINONE; NONSTEROID ANTIINFLAMMATORY AGENT; PROTEIN BAX; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; SHIKONIN; STRESS ACTIVATED PROTEIN KINASE;

APOPTOSIS; BIOSYNTHESIS; CELL LINE; CELL PROLIFERATION; CYTOLOGY; DRUG EFFECTS; EPITHELIUM CELL; GROWTH, DEVELOPMENT AND AGING; HUMAN; LENS; METABOLISM; MITOCHONDRIAL MEMBRANE POTENTIAL; PHOSPHORYLATION;

ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CASPASE 3; CASPASE 7; CASPASE 9; CASPASE INHIBITORS; CELL LINE; CELL PROLIFERATION; DRUGS, CHINESE HERBAL; EPITHELIAL CELLS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; LENS, CRYSTALLINE; MEMBRANE POTENTIAL, MITOCHONDRIAL; NAPHTHOQUINONES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-BCL-2; REACTIVE OXYGEN SPECIES;

EID: 84903287499     PISSN: None     EISSN: 14203049     Source Type: Journal    
DOI: 10.3390/molecules19067785     Document Type: Article

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