The role of the neuroendocrine and immune systems in the pathogenesis of depression

Pharmacological Reports

Volumn 66, Issue 5, 2014, Pages 776-781

  Ogłodek, Ewa ^a   Szota, Anna ^a   Just, Marek ^b   Moś, Danuta ^c   Araszkiewicz, Aleksander ^a  

^a NICOLAUS COPERNICUS UNIVERSITY   (Poland)

^b Municipal Hospital in Piekary la skie   (Poland)

^c Health Care Centre Euro Med Bytom   (Poland)

Author keywords

Allostasis; Depression; Immune system; Neuroendocrine system

Indexed keywords

CHEMOKINE; CHEMOKINE RECEPTOR; CORTICOTROPIN; CORTICOTROPIN RELEASING FACTOR; HYDROCORTISONE; BRAIN DERIVED NEUROTROPHIC FACTOR; CYTOKINE;

CELLULAR IMMUNITY; CHRONIC STRESS; COGNITIVE DEFECT; CYTOKINE RELEASE; DEPRESSION; DISEASE SEVERITY; HUMAN; IMMUNE SYSTEM; IMMUNOREGULATION; NERVE DEGENERATION; NEUROENDOCRINE SYSTEM; NONHUMAN; PATHOPHYSIOLOGY; PROTEIN FUNCTION; REVIEW; ALLOSTASIS; ANIMAL; METABOLISM; NEUROSECRETION; PHYSIOLOGICAL STRESS; PHYSIOLOGY; SEVERITY OF ILLNESS INDEX;

ALLOSTASIS; ANIMALS; BRAIN-DERIVED NEUROTROPHIC FACTOR; CYTOKINES; DEPRESSION; HUMANS; IMMUNE SYSTEM; NEUROSECRETORY SYSTEMS; SEVERITY OF ILLNESS INDEX; STRESS, PHYSIOLOGICAL;

EID: 84903281070     PISSN: 22995684     EISSN: 22995684     Source Type: Journal    
DOI: 10.1016/j.pharep.2014.04.009     Document Type: Review

References (70)

1. R.W. Lam, G.S. Malhi, R.S. McIntyre, K. Demyttenaere, P. Gorwood, and E.E. Michalak et al. Fatigue and occupational functioning in major depressive disorder Aust N Z J Psychiatry 47 11 2013 989 991
2. B.S. McEwen Sex, stress and the hippocampus: allostasis, allostatic load and the aging process Neurobiol Aging 23 5 2002 921 939
3. B.S. McEwen, and J.C. Wingfield The concept of allostasis in biology and biomedicine Horm Behav 43 1 2003 2 15
4. B.S. McEwen Mood disorders and allostatic load Biol Psychiatry 54 2003 200 207
5. B. Bondy Pathophysiology of depression and mechanism of treatment Dialogues Clin Neurosci 4 1 2002 7 20
6. N. Quan, and W.A. Banks Brain-immune communication pathways Brain Behav Immun 21 6 2007 727 735
7. C.L. Raison, A.S. Borisov, M. Majer, D.F. Drake, G. Pagnoni, and B.J. Woolwine et al. Activation of central nervous system inflammatory pathways by interferon-alpha: relationship to monoamines and depression Biol Psychiatry 65 4 2009 296 303
8. T.W. Robbins, and A.F. Arnsten The neuropsychopharmacology of fronto-executive function: monoaminergic modulation Annu Rev Neurosci 32 2009 267 287
9. D.C. Poon, Y.S. Ho, K. Chiu, and R.C. Chang Cytokines: how important are they in mediating sickness? Neurosci Biobehav Rev 37 1 2013 1 10
10. E. Pralong, P. Magistretti, and R. Stoop Cellular perspectives on the glutamate-monoamine interactions in limbic lobe structures and their relevance for some psychiatric disorders Prog Neurobiol 67 3 2002 173 202
11. M. Maes, B.E. Leonard, A.M. Myint, M. Kubera, and R. Verkerk The new '5-HT' hypothesis of depression: cell-mediated immune activation induces indoleamine 2,3-dioxygenase, which leads to lower plasma tryptophan and an increased synthesis of detrimental tryptophan catabolites (TRYCATs), both of which contribute to the onset of depression Prog Neuropsychopharmacol Biol Psychiatry 35 3 2011 702 721
12. P.F. Schuck, A. Tonin, G. da Costa Ferreira, C.M. Viegas, A. Latini, and C.M. Duval Wannmacher et al. Kynurenines impair energy metabolism in rat cerebral cortex Cell Mol Neurobiol 27 2007 147 160
13. H. Baran, K. Staniek, B. Kepplinger, J. Stur, M. Draxler, and H. Nohl Kynurenines and the respiratory parameters on rat heart mitochondria Life Sci 72 10 2003 1103 1115
14. D.L. Feinstein, M.T. Heneka, V. Gavrilyuk, C. Dello Russo, G. Weinberg, and E. Galea Noradrenergic regulation of inflammatory gene expression in brain Neurochem Int 41 5 2002 357 365
15. J. Lekakis, I. Ikonomidis, Z. Papoutsi, P. Moutsatsou, M. Nikolaou, and J. Parissis et al. Selective serotonin re-uptake inhibitors decrease the cytokine-induced endothelial adhesion molecule expression, the endothelial adhesiveness to monocytes and the circulating levels of vascular adhesion molecules Int J Cardiol 139 2 2010 150 158
16. J.E. Piletz, A. Halaris, O. Iqbal, D. Hoppensteadt, J. Fareed, and H. Zhu et al. Pro-inflammatory biomakers in depression: treatment with venlafaxine World J Biol Psychiatry 10 4 2009 313 323
17. J. Podlipný, Z. Hess, J. Vrzalová, H. Rosolová, J. Beran, and B. Petrlová Lower serum levels of interleukin-6 in a population sample with symptoms of depression than in a population sample without symptoms of depression Physiol Res 59 1 2010 121 126
18. H. Himmerich, E.B. Binder, H.E. Künzel, A. Schuld, S. Lucae, and M. Uhr et al. Successful antidepressant therapy restores the disturbed interplay between TNF-α system and HPA axis Biol Psychiatry 60 8 2006 882 888
19. G. Racagni, and M. Popoli Cellular and molecular mechanisms in the long-term action of antidepressants Dialogues Clin Neurosci 10 4 2008 385 400
20. R. Dantzer, J.P. Konsman, R.M. Bluthé, and K.W. Kelley Neural and humoral pathways of communication from the immune system to the brain: parallel or convergent? Auton Neurosci 85 1-3 2000 60 65
21. J.K. Kiecolt-Glaser, and R. Glaser Depression and immune function: central pathways to morbidity and mortality J Psychosom Res 53 4 2002 873 876
22. D. Lindqvist, S. Janelidze, S. Erhardt, L. Träskman-Bendz, G. Engström, and L. Brundin CSF biomarkers in suicide attempters - a principal component analysis Acta Psychiatr Scand 124 1 2011 52 61
23. W.A. Banks The blood-brain barrier in psychoneuroimmunology Neurol Clin 24 3 2006 413 419
24. L. Cosmi, F. Liotta, R. Angeli, B. Mazzinghi, V. Santarlasci, and R. Manetti et al. Th2 cells are less susceptible than Th1 cells to the suppressive activity of CD25+ regulatory thymocytes because of their responsiveness to different cytokines Blood 103 8 2004 3117 3121
25. B. Curran, and J.J. O'Connor The pro-inflammatory cytokine interleukin-18 impairs long-term potentiation and NMDA receptor-mediated transmission in the rat hippocampus in vitro Neuroscience 108 1 2001 83 90
26. R.A. Kohman, and J.S. Rhodes Neurogenesis, inflammation and behavior Brain Behav Immun 27 1 2013 22 32
27. 2+ signaling Science 327 5970 2010 1250 1254
28. M.C. Wichers, G. Kenis, C. Leue, G. Koek, G. Robaeys, and M. Maes Baseline immune activation as a risk factor for the onset of depression during interferon-alpha treatment Biol Psychiatry 60 1 2006 77 79
29. M. Wichers, and M. Maes The psychoneuroimmuno-pathophysiology of cytokine-induced depression in humans Int J Neuropsychopharmacol 5 4 2002 375 388
30. S.O. Nunes, E.M. Reiche, H.K. Morimoto, T. Matsuo, E.N. Itano, and E.C. Xavier et al. Immune and hormonal activity in adults suffering from depression Braz J Med Biol Res 35 5 2002 581 587
31. L.L. Altshuler, O.A. Abulseoud, L. Foland-Ross, G. Bartzokis, S. Chang, and J. Mintz et al. Amygdala astrocyte reduction in subjects with major depressive disorder but not bipolar disorder Bipolar Disord 12 5 2010 541 549
32. A. Araque, and M. Navarrete Glial cells in neuronal network function Philos Trans R Soc Lond B Biol Sci 365 1551 2010 2375 2381
33. J. Zhu, X. Wei, J. Liu, Y. Hu, and J. Xu Interaction of glia activation and neurotransmission in hippocampus of neuropathic rats treated with mirtazapine Exp Clin Psychopharmacol 17 3 2009 198 203
34. B. Viviani, and M. Boraso Cytokines and neuronal channels: a molecular basis for age related decline of neuronal function? Exp Gerontol 46 2-3 2011 199 206
35. R.L. Huger, S.G. Shelat, and E.E. Redei Decreased corticotrophin- releasing factor receptor expression and adrenocorticotropin hormone responsiveness in anterior pituitary cella of Wistar Kyoto rats J Neuroendocrinol 14 2 2002 126 134
36. R. Krishnadas, and J. Cavanagh Depression: an inflammatory illness? J Neurol Neurosurg Psychiatry 83 5 2012 495 502
37. Z. Kronfol Immune dysregulation in major depression: a critical review of existing evidence Int J Neuropsychopharmacol 5 4 2002 333 343
38. M. Baggiolini Chemokines and leukocyte traffic Nature 392 6676 1998 565 568
39. G.E. Miller, N. Rohleder, C. Stetler, and C. Kirschbaum Clinical depression and regulation of the inflammatory response during acute stress Psychosom Med 67 5 2005 679 687
40. H. Eyre, and B.T. Baune Neuroplastic changes in depression: a role for the immune system Psychoneuroendocrinology 37 9 2012 416 1397
41. J. Isung, F. Mobarrez, P. Nordström, M. Asberg, and J. Jokinen Low plasma vascular endothelial growth factor (VEGF) associated with completed suicide World J Biol Psychiatry 13 6 2012 468 473
42. H. Jozuka, E. Jozuka, S. Takeuchi, and O. Nishikaze Comparison of immunological and endocrinological markers associated with major depression J Int Med Res 31 1 2003 36 41
43. N. Lichtblau, F.M. Schmidt, R. Schumann, K.C. Kirkby, and H. Himmerich Cytokines as biomarkers in depressive disorder: current standing and prospects Int Rev Psychiatry 25 5 2013 592 603
44. G. Constantin Chemokine signaling and integrin activation in lymphocyte migration into the inflamed brain J Neuroimmunol 198 1-2 2008 20 26
45. P.F. Schuck, A. Tonin, G. da Costa Ferreira, C.M. Viegas, A. Latini, and C.M. Duval Wannmacher et al. Kynurenines impair energy metabolism in rat cerebral cortex Cell Mol Neurobiol 27 1 2007 147 160
46. S. Moylan, M. Maes, N.R. Wray, and M. Berk The neuroprogressive nature of major depressive disorder: pathways to disease evolution and resistance, and therapeutic implications Mol Psychiatry 18 5 2013 595 606
47. M. Maes, K. Ringel, M. Kubera, M. Berk, and J.K. Rybakowski Increased autoimmune activity against 5-HT: a key component of 3 depression that is associated with inflammation and activation of cell-mediated immunity, and with severity and staging of depression J Affect Disord 136 3 2012 386 392
48. R.P. Jusster, B.S. Mc Ewen, and S.J. Lupien Allostatic load biomarkers of chronic stress and impact on health and cognition Neurosci Biobehav Rev 35 1 2010 2 16
49. F. Kapczinski, V.V. Dias, M. Kauer-Sant'Anna, B.N. Frey, R. Grassi-Oliveira, and F. Colom et al. Clinical implications of a staging model for bipolar disorders Expert Rev Neurother 9 7 2009 957 966
50. I.N. Karatsoreos, and B.S. McEwen Psychobiological allostasis: resistance, resilience and vulnerability Trends Cogn Sci 15 12 2011 576 584
51. B.S. Mc Ewen Allostasis and allostatic load: implications for neuropsychopharmacology Neuropsychopharmacology 22 2 2000 108 124
52. J.K. Kiecolt-Glaser, T.J. Loving, J.R. Stowell, W.B. Malarkey, S. Lemeshow, and S.L. Dickinson et al. Hostile marital interactions, proinflammatory cytokine production, and wound healing Arch Gen Psychiatry 62 12 2005 1377 1384
53. Y.K. Kim, S.W. Lee, S.H. Kim, S.H. Shim, S.W. Han, and S.H. Choi et al. Differences in cytokines between non-suicidal patients and suicidal patients in major depression Prog Neuropsychopharmacol Biol Psychiatry 32 2 2008 356 361
54. E. Haroon, C.L. Raison, and A.H. Miller Psychoneuroimmunology meets neuropsychopharmacology: translational implications of the impact of inflammation on behavior Neuropsychopharmacology 37 1 2012 137 162
55. O.J. Schiepers, M.C. Wichers, and M. Maes Cytokines and major depression Prog Neuropsychopharmacol Biol Psychiatry 29 2 2005 201 217
56. S. Lanquillon, J.C. Krieg, U. Bening-Abu-Shach, and H. Vedder Cytokine production and treatment response in major depressive disorder Neuropsychopharmacology 22 4 2000 370 379
57. I.F. Charo, and R.M. Ransohoff The many roles of chemokines and chemokine receptors in inflammation N Engl J Med 354 6 2006 610 621
58. M. Maes Depression is an inflammatory disease, but cell-mediated immune activation is the key component of depression Prog Neuropsychopharmacol Biol Psychiatry 35 3 2011 664 675
59. B.E. Leonard, and M. Maes Mechanistic explanations how cell-mediated immune activation, inflammation and oxidative and nitrosative stress pathways and their sequels and concomitants play a role in the pathophysiology of unipolar depression Neurosci Biobehav Rev 36 2 2012 764 785
60. V. Vaccarino, M.L. Brennan, A.H. Miller, J.D. Bremner, J.C. Ritchie, and F. Lindau et al. Association of major depressive disorder with serum myeloperoxidase and other markers of inflammation: a twin study Biol Psychiatry 64 6 2008 476 483
61. G. Sanacora, G. Treccani, and M. Popoli Towards a glutamate hypothesis of depression: an emerging frontier of neuropsychopharmacology for mood disorders Neuropharmacology 62 1 2012 63 77
62. J.B. O'Sullivan, K.M. Ryan, A. Harkin, and T.J. Connor Noradrenaline reuptake inhibitors inhibit expression of chemokines IP-10 and RANTES and cell adhesion molecules VCAM-1 and ICAM-1 in the CNS following a systemic inflammatory challenge J Neuroimmunol 220 1-2 2010 34 42
63. L. Sutcigil, C. Oktenli, U. Musabak, A. Bozkurt, A. Cansever, and O. Uzun et al. Pro- and anti-inflammatory cytokine balance in major depression: effect of sertraline therapy Clin Dev Immunol 2007 2007 76396
64. S. Rajagopalan, R. Brook, M. Rubenfire, E. Pitt, E. Young, and B. Pitt Abnormal brachial artery flow-mediated vasodilation in young adults with major depression Am J Cardiol 88 1 2001 196 198
65. S.J. Motivala, A. Sarfatti, L. Olmos, and M.R. Irwin Inflammatory markers and sleep disturbance in major depression Psychosom Med 67 2 2005 187 194
66. Y.D. Shen, P.L. Lu, X.Y. Hu, X.M. Tong, and W. Chen The plasma IL-18, MIP-1a, MCP-1, SDF-1 and Rantes in patients with major depression Eur Psychiatry 23 2 2008 245
67. Z. Cai, X. Zhang, G. Wang, H. Wang, Z. Liu, and X. Guo et al. BDNF attenuates IL-1beta-induced F-actin remodeling by inhibiting NF-kappaB signaling in hippocampal neurons Neuro Endocrinol Lett 35 1 2014 13 19
68. R.S. Duman Neurobiology of stress, depression, and rapid acting antidepressants: remodeling synaptic connections Depress Anxiety 31 4 2014 291 296
69. S.M. Lehto, L. Niskanen, K.H. Herzig, T. Tolmunen, A. Huotari, and H. Viinamäki et al. Serum chemokine levels in major depressive disorder Psychoneuroendocrinology 35 2 2010 226 232
70. L. Wang, D. Peng, B. Xie, K. Jiang, and Y. Fang The extracellular signal-regulated kinase pathway may play an important role in mediating antidepressant-stimulated hippocampus neurogenesis in depression Med Hypotheses 79 1 2012 87 91