The extracellular signal-regulated kinase pathway may play an important role in mediating antidepressant-stimulated hippocampus neurogenesis in depression

Medical Hypotheses

Volumn 79, Issue 1, 2012, Pages 87-91

  Wang, Lingxiao ^a   Peng, Daihui ^a   Xie, Bin ^a   Jiang, Kaida ^a   Fang, Yiru ^a  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

[No Author keywords available]

Indexed keywords

AGOMELATINE; ANTIDEPRESSANT AGENT; ESCITALOPRAM; FLUOXETINE; MITOGEN ACTIVATED PROTEIN KINASE; MOOD STABILIZER; TIANEPTINE;

ARTICLE; DEPRESSION; DRUG TARGETING; HIPPOCAMPUS; HUMAN; MOLECULAR PATHOLOGY; NERVE CELL PLASTICITY; NERVOUS SYSTEM DEVELOPMENT; NEUROPATHOLOGY; NONHUMAN; PROTEIN FUNCTION; SIGNAL TRANSDUCTION;

ANIMALS; ANTIDEPRESSIVE AGENTS; DEPRESSION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HIPPOCAMPUS; HUMANS; MODELS, ANIMAL; MODELS, THEORETICAL; NEUROGENESIS; SIGNAL TRANSDUCTION;

ANIMALIA;

EID: 84861454418     PISSN: 03069877     EISSN: 15322777     Source Type: Journal    
DOI: 10.1016/j.mehy.2012.04.008     Document Type: Article

References (66)

1. Lee Saebom, Jeong Jaehoon, Kwak Yongdo, Park Sang Ki Depression research: where are we now?. Mol Brain 2010, 3:8.
2. Thomas Gareth M., Huganir Richard L. Mark cascade signalling and synaptic plasticity. Nat Rev 2004, 5(3):173-183.
3. Alcorta D.A., Crews C.M., Sweet L.J., Bankston L., Jones S.W., Erikson R.L. Sequence and expression of chicken and mouse rsk: homologs of Xenopus laevis ribosomal S6 kinase. Mol Cell Biol 1989, 9(9):3850-3859.
4. Deak M., Clifton A.D., Lucocq L.M., Alessi D.R. Mitogen- and stress-activated protein kinase-1 (MSK1) is directly activated by MAPK and SAPK2/p38, and may mediate activation of CREB. EMBO J 1996, 17(15):4426-4441.
5. Schaeffer H.J., Weber M.J. Mitogen-activated protein kinases: specific messages from ubiquitous messengers. Mol Cell Biol 1999, 19(4):2435-2444.
6. Choi Y.S., Cho H.Y., Hoyt K.R., Naegele J.R., Obrietan K. IGF-1 receptor-mediated ERK/MAPK signaling couples status epilepticus to progenitor cell proliferation in the subgranular layer of the dentate gyrus. Glia 2008, 56(7):791-800.
7. Atkins C.M., Selcher, Petraitis J.J., Trzaskos J.M., Sweatt J.D. The MAPK cascade is required for mammalian associative learning. Nat Neurosci. 1998, 1(7):602-609.
8. Gage F.H. Mammalian neural stem cells. Science 2000, 287(5457):1433-1438.
9. Fukuda S., Kato F., Tozuka Y., Yamaguchi M., Miyamoto Y., Hisatsune T. Two distinct subpopulations of nestin-positive cells in adult mouse dentate gyrus. J Neurosci 2003, 23(28):9357-9366.
10. Steiner B., Klempin F., Wang L., Kott M., Kettenmann H., Kempermann G. Type-2 cells as link between glial and neuronal lineage in adult hippocampal neurogenesis. Glia 2006, 54(8):805-814.
11. Zhao C., Deng W., Gage F.H. Mechanisms and functional implications of adult neurogenesis. Cell 2008, 132:645-660.
12. Drew M.R., Hen R. Adult hippocampal neurogenesis as target for the treatment of depression. CNS Neurol Disord Drug Targets 2007, 6:205-218.
13. Videbech P., Ravnkilde B. Hippocampal volume and depression: a meta-analysis of MRI studies. Am J Psych 2004, 161(11):1957-1966.
14. Drevets W.C. Neuroimaging studies of mood disorders: implications for a neural model of major depression. Biol Psychiatr 2000, 48(8):813-829.
15. Sheline Y.I., Sanghavi M., Mintun M.A., Gado M.H. Depression duration but not age predicts hippocampal volume loss in medically healthy women with recurrent major depression. J Neurosci 1999, 19(12):5034-5043.
16. MacQueen G.M., Campbell S., McEwen B.S., et al. Course of illness, hippocampal function, and hippocampal volume inmajor depression. Proc Natl Acad Sci USA 2003, 100:1387-1392.
17. Dranovsky Alex., Hen René. Hippocampal neurogenesis: regulation by stress and antidepressants. Biol Psychiatr 2006, 59:1136-1143.
18. Malberg J.E., Duman R.S. Cell proliferation in adult hippocampus is decreased by inescapable stress: reversal by fluoxetine treatment. Neuropsychopharmacology 2003, 28:1562-1571.
19. Lee K.-J., Kim S.-J., Kim S.-W., et al. Chronic mild stress decreases survival, but not proliferation, of new-born cells in adult rat hippocampus. Exp Mol Med 2006, 38(1):44-54.
20. Santarelli L., Saxe M., Gross C., et al. Requirement of hippocampal neurogenesis for the behavioral effects of antidepressants. Science 2003, 301:805-809.
21. Malberg J.E., Eisch A.J., Nestler E.J., Duman R.S. Chronic antidepressant treatment increases neurogenesis in adult rat hippocampus. J Neurosci 2000, 20(9):104-110.
22. Malberg Jessica E., Eisch Amelia J., Nestler Eric J., Duman Ronald S. Chronic antidepressant treatment increases neurogenesis in adult rat hippocampus. J Neurosci 2000, 20(24):9104-9110.
23. Jayatissa M.N., Bisgaard C., Tingström A., Papp M., Wiborg O. Hippocampal cytogenesis correlates to escitalopram-mediated recovery in a chronic mild stress rat model of depression. Neuropsychopharmacology 2006, 31:2395-2404.
24. Banasr M., Soumier A., Hery M., Mocaër E., Daszuta A. Agomelatine, a new antidepressant, induces regional changes in hippocampal neurogenesis. Biol Psychiatr 2006, 59(11):1087-1096.
25. Chen G., Rajkowska G., Du F., Seraji-Bozorgzad N., Manji H.K. Enhancement of hippocampal neurogenesis by lithium. J Neurochem 2000, 4(75):1729-1734.
26. Brown J., Cooper-Kuhn C.M., Kempermann G., et al. Enriched environment and physical activity stimulate hippocampal but not olfactory bulb neurogenesis. Eur J Neurosci 2003, 17(10):2042-2046.
27. Warner-Schmidt J.L., Duman R.S. Hippocampal neurogenesis: opposing effects of stress and antidepressant treatment. Hippocampus 2006, 16:239-249.
28. Encinas J.M., Vaahtokari A., Enikolopov G. Fluoxetine targets early progenitor cells in the adult brain. Proc Natl Acad Sci USA 2006, 103:8233-8238.
29. Segi-Nishida E., Warner-Schmidt J.L., Duman R.S. Electroconvulsive seizure and VEGF increase the proliferation of neural stem-like cells in rat hippocampus. Proc Natl Acad Sci USA 2008, 105:11352-11357.
30. Lugert Sebastian., Basak Onur., Knuckles Philip., et al. Quiescent and active hippocampal neural stem cells with distinct morphologies respond selectively to physiological and pathological stimuli and aging. Cell Stem Cell 2010, 6:445-456.
31. Li Y., Peng Z., Xiao B., Houser C.R. Activation of ERK by spontaneous seizures in neural progenitors of the dentate gyrus in a mouse model of epilepsy. Exp Neurol 2010, 224:133-145.
32. Xiao Zhifeng, Kong Yaxian, Yang Shufa, Li Meiyu, Wen Jinhua, Li Lingsong Upregulation of Flk-1 by bFGF via the ERK pathway is essential for VEGF-mediated promotion of neural stem cell proliferation. Cell Res 2007, 17:73-79.
33. Airan R.D., Meltzer L.A., Roy M., Gong Y., Chen H., Deisseroth K. High-speed imaging reveals neurophysiological links to behavior in an animal model of depression. Science 2007, 317(5839):819-823.
34. Meshi D., Drew M.R., Saxe M. Hippocampal neurogenesis is not required for behavioral effects of environmental enrichment. Nat Neurosci 2006, 9(6):729-731.
35. David Denis J., Samuels Benjamin Adam, Rainer Quentin Behavioral effects of fluoxetine in an animal model of anxiety/depression are mediated by both neurogenesis-dependent and independent mechanisms. Neuron 2009, 62(4):479-493.
36. Perera Tarique D., Dwork Andrew J., Keegan Kathryn A. Necessity of hippocampal neurogenesis for the therapeutic action of antidepressants in adult nonhuman primates. PLoS ONE 2011, 6(4):e17600.
37. Gur T.L., Conti A.C., Holden J., et al. CAMP response element-binding protein deficiency allows for increased neurogenesis and a rapid onset of antidepressant response. J Neurosci 2007, 27(29):7860-7868.
38. Marinissen M.J., Gutkind J.S. G-protein-coupled receptors and signaling networks: emerging paradigms. Trends Pharmacol Sci 2001, 22(7):368-376.
39. Huang E.J., Reichardt L.F. TRK receptors: roles in neuronal signal transduction. Annu Rev Biochem 2003, 72:609-642.
40. Lange-Carter C.A., Johnson G.L. Ras-dependent growth factor regulation of MEK kinase in PC12 cells. Science 1994, 265:1458-1461.
41. Menard C., Hein P., Paquin A., et al. An essential role for aMEK-C/EBP pathway during growth factor-regulated cortical neurogenesis. Neuron 2002, 36:597-610.
42. Tian He-Ping., Huang Bao-Sheng, Zhao Jie Non-receptor tyrosine kinase Src is required for ischemia-stimulated neuronal cell proliferation via Raf/ERK/CREB activation in the dentate gyrus. BMC Neurosci 2009, 10:139.
43. Hao Y., Creson T., Zhang L., et al. Mood stabilizer valproate promotes ERK pathway dependent cortical neuronal growth and neurogenesis. J Neurosci 2004, 24:6590-6599.
44. Yan X.B., Hou H.L., Wu L.M., Liu J., Zhou J.N. Lithium regulates hippocampal neurogenesis by ERK pathway and facilitates recovery of spatial learning and memory in rats after transient global cerebral ischemia. Neuropharmacology 2007, 53(4):487-495.
45. Li B.S., Ma W., Zhang L., Barker J.L., Stenger D.A., Pant H.C. Activation of phosphatidylinositol-3 kinase (PI-3K) and extracellular regulated kinases (Erk1/2) is involved in muscarinic receptor-mediated DNA synthesis in neural progenitor cells. J Neurosci 2001, 21:1569-1579.
46. Jin K., Mao X.O., Del Rio Guerra G., Jin L., Greenberg D.A. Heparin-binding epidermal growth factor-like growth factor stimulates cell proliferation in cerebral cortical cultures through phosphatidylinositol 3-kinase and mitogen-activated protein kinase. J Neurosci Res 2005, 81(4):497-505.
47. Barnabe-Heider F., Miller F.D. Endogenously produced neurotrophins regulate survival and differentiation of cortical progenitors via distinct signaling pathways. J Neurosci 2003, 23(12):5149-5160.
48. Wu X., Reiter C.E., Antonetti D.A., Kimball S.R., Jefferson L.S., Gardner T.W. Insulin promotes rat retinal neuronal cell survival in a p70S6K-dependent manner. J Biol Chem 2004, 279(10):9167-9175.
49. Nitta A., Zheng Wh., Quirion R. Insulin-like growth factor 1 prevents neuronal cell death induced by corticosterone through activation of the PI3k/Akt pathway. J Neurosci Res 2004, 76(1):98-103.
50. Sinha D., Wang Z., Ruchalski K.L., et al. Lithium activates the Wnt and phos-phatidylinositol 3-kinase Akt signaling pathway to promote cell survival in the absence of soluble survival factors. Am J Physiol Renal Physiol 2005, 288(4):F703-F713.
51. Bruel-Jungerman E., Veyrac A., Dufour F., Horwood J., Laroche S., Davis S. Inhibition of PI3K-Akt signaling blocks exercise-mediated enhancement of adult neurogenesis and synaptic plasticity in the dentate gyrus. PLoS ONE 2009, 4(11):e7901.
52. Creson Thomas K., Yuan Peixiong, Manji Husseini K. Evidence for involvement of ERK, PI3K, and RSK in induction of Bcl-2 by valproate. J Mol Neurosci 2009, 37(2):123-134.
53. Finkbeiner S., Tavazoie S.F., Maloratsky A., Jacobs K.M., Harris K.M., Greenberg M.E. CREB: a major mediator of neuronal neurotrophin responses. Neuron 1997, 19:1031-1047.
54. Thome J., Shakai N., Shin K., et al. cAMP response element-mediated gene transcription is upregulated by chronic antidepressant treatment. J. Neurosci 2000, 20(11):4030-4036.
55. Nibuya M., Nestler E.J., Duman R.S. Chronic antidepressant administration increases the expression of cAMP response element binding protein (CREB) in rat hippocampus. J. Neurosci 1996, 16:2365-2372.
56. Jeon S.H., Seong Y.S., Juhnn Y.S., et al. Electroconvulsive shock increases the phosphorylation of cyclic AMP response element binding protein at Ser-133 in rat hippocampus but not in cerebellum. Neuropharmacology 1997, 36(3):411-414.
57. Meller E., Nikolao T.A., et al. Region-specific effects of acute and repeated restraint stress on the phosphorylation of mitogen-activated protein kinases. Brain Res 2003, 979(1-2):57-64.
58. Feng P., Guan Z., Yang X., Fang J. Impairments of ERK signal transduction in the brain in a rat model of depression induced by neonatal exposure of clomipramine. Brain Res 2003, 991(1-2):195-205.
59. Dwivedi Y., Rizavi H.S., Roberts R.C., Conley R.C., Tamminga C.A., Pandey G.N. Reduced activation and expression of ERK1/2 MAP kinase in the post-mortembrain of depressed suicide subjects. J Neurochem 2001, 77(3):916-928.
60. Nibuya M., Morinobu S., Duman R.S. Regulation of BDNF and trkB mRNA in rat brain by chronic electroconvulsive seizure and antidepres sant drug treatments. J Neurosci 1995, 15(11):7539-7547.
61. Russo-Neustadt A., Beard R.C., Huang Y.M., Cotman C.W. Physical activity and antidepressant treatment potentiate the expression of specific brain-derived neurotrophic factor transcripts in the rat hippocampus. Neuroscience 2000, 101(2):305-312.
62. Mercier G., Lennon A.M., Renouf, et al. MAP kinase activation by fluoxetine and its relation to gene expression in cultured rat astrocytes. J Mol Neurosci 2004, 24(2):207-216.
63. Qi Xiaoli, Lin Wenjuan, Li Junfa, et al. Fluoxetine increases the activity of the ERK-CREB signal system and alleviates the depressive-like behavior in rats exposed to chronic forced swim stress. Neurobiol Disease 2008, 31(2):278-285.
64. Tiraboschi E., Tardito D., Kasahara J., et al. Selective phosphorylation of nuclear CREB by fluoxetine is linked to activation of CaM kinase IV and MAP kinase cascades. Neuropsychopharmacology 2004, 29(10):1831-1840.
65. Shirayama Y., Russell D.S., Duman R.S. Brain derived neurotrophic factor produces antidepressant effects in behavioral models of depression. J Neurosci 2001, 22(8):3251-3261.
66. Duman C.H., Schlesinger L., Kodama M., Russell D.S., Duman R.S. A role for MAP kinase signaling in behavioral models of depression and antidepressant treatment. Biol Psychiatr 2007, 61(5):661-670.