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Volumn 136, Issue 3, 2012, Pages 386-392

Increased autoimmune activity against 5-HT: A key component of depression that is associated with inflammation and activation of cell-mediated immunity, and with severity and staging of depression

Author keywords

Autoimmunity; Cytokines; Depression; Fatigue and somatic symptoms; Inflammation; Serotonin

Indexed keywords

INTERLEUKIN 1; LYSOZYME; NEOPTERIN; SEROTONIN; TUMOR NECROSIS FACTOR ALPHA;

EID: 84857361203     PISSN: 01650327     EISSN: 15732517     Source Type: Journal    
DOI: 10.1016/j.jad.2011.11.016     Document Type: Article
Times cited : (91)

References (69)
  • 1
    • 79959994418 scopus 로고    scopus 로고
    • Fluoxetine regulates the expression of neurotrophic/growth factors and glucose metabolism in astrocytes
    • I. Allaman, H. Fiumelli, P.J. Magistretti, and J.L. Martin Fluoxetine regulates the expression of neurotrophic/growth factors and glucose metabolism in astrocytes Psychopharmacology 216 1 2011 75 84
    • (2011) Psychopharmacology , vol.216 , Issue.1 , pp. 75-84
    • Allaman, I.1    Fiumelli, H.2    Magistretti, P.J.3    Martin, J.L.4
  • 2
    • 0028360255 scopus 로고
    • Circulating autoantibodies directed against conjugated fatty acids in sera of HIV-1-infected patients
    • A. Amara, C. Chaugier, J.M. Ragnaud, and M. Geffard Circulating autoantibodies directed against conjugated fatty acids in sera of HIV-1-infected patients Clinical and Experimental Immunology 96 3 1994 379 383
    • (1994) Clinical and Experimental Immunology , vol.96 , Issue.3 , pp. 379-383
    • Amara, A.1    Chaugier, C.2    Ragnaud, J.M.3    Geffard, M.4
  • 7
    • 79958290000 scopus 로고    scopus 로고
    • Emerging tendency towards autoimmune process in major depressive patients: A novel insight from Th17 cells
    • Y. Chen, T. Jiang, P. Chen, J. Ouyang, G. Xu, Z. Zeng, and Y. Sun Emerging tendency towards autoimmune process in major depressive patients: a novel insight from Th17 cells Psychiatry Research 188 2 2011 224 230
    • (2011) Psychiatry Research , vol.188 , Issue.2 , pp. 224-230
    • Chen, Y.1    Jiang, T.2    Chen, P.3    Ouyang, J.4    Xu, G.5    Zeng, Z.6    Sun, Y.7
  • 8
    • 0017228734 scopus 로고
    • Antinuclear factor-positive mental depression: A single disease entity?
    • R. Deberdt, J. Van Hooren, M. Biesbrouck, and W. Amery Antinuclear factor-positive mental depression: a single disease entity? Biological Psychiatry 11 1 1976 69 74
    • (1976) Biological Psychiatry , vol.11 , Issue.1 , pp. 69-74
    • Deberdt, R.1    Van Hooren, J.2    Biesbrouck, M.3    Amery, W.4
  • 9
    • 2442525920 scopus 로고    scopus 로고
    • Serotonin and neurogenesis in the hippocampal dentate gyrus of adult mammals
    • R.L. Djavadian Serotonin and neurogenesis in the hippocampal dentate gyrus of adult mammals Acta Neurobiologiae Experimentalis 64 2 2004 189 200
    • (2004) Acta Neurobiologiae Experimentalis , vol.64 , Issue.2 , pp. 189-200
    • Djavadian, R.L.1
  • 10
    • 0018848094 scopus 로고
    • Enzyme immunoassay ELISA and EMIT
    • E. Engvall Enzyme immunoassay ELISA and EMIT Methods in Enzymology 70(A) 1980 419 439
    • (1980) Methods in Enzymology , vol.70 A , pp. 419-439
    • Engvall, E.1
  • 12
    • 1042301128 scopus 로고    scopus 로고
    • Detection of the specific IgM and IgA circulating in sera of multiple sclerosis patients: Interest and perspectives
    • C.M. Geffard, D. Bodet, Y. Martinet, and M.-P. Dabadie Detection of the specific IgM and IgA circulating in sera of multiple sclerosis patients: interest and perspectives Immuno-Analyse & Biologie Specialisee 17 2002 302 310
    • (2002) Immuno-Analyse & Biologie Specialisee , vol.17 , pp. 302-310
    • Geffard, C.M.1    Bodet, D.2    Martinet, Y.3    Dabadie, M.-P.4
  • 14
    • 71349087879 scopus 로고    scopus 로고
    • Low-dose tryptophan depletion in recovered depressed women induces impairments in autobiographical memory specificity
    • A.D. Haddad, J.M. Williams, S.F. McTavish, and C.J. Harmer Low-dose tryptophan depletion in recovered depressed women induces impairments in autobiographical memory specificity Psychopharmacology 207 3 2009 499 508
    • (2009) Psychopharmacology , vol.207 , Issue.3 , pp. 499-508
    • Haddad, A.D.1    Williams, J.M.2    McTavish, S.F.3    Harmer, C.J.4
  • 16
    • 80054745701 scopus 로고    scopus 로고
    • The effect of antidepressant medication treatment on serum levels of inflammatory cytokines: A meta-analysis
    • J. Hannestad, N. Dellagioia, and M. Bloch The effect of antidepressant medication treatment on serum levels of inflammatory cytokines: a meta-analysis Neuropsychopharmacology 36 12 2011 2452 2459
    • (2011) Neuropsychopharmacology , vol.36 , Issue.12 , pp. 2452-2459
    • Hannestad, J.1    Dellagioia, N.2    Bloch, M.3
  • 17
    • 33644649377 scopus 로고    scopus 로고
    • Brain 5-HT synthesis in the Flinders Sensitive Line rat model of depression: An autoradiographic study
    • S. Hasegawa, K. Nishi, A. Watanabe, D.H. Overstreet, and M. Diksic Brain 5-HT synthesis in the Flinders Sensitive Line rat model of depression: an autoradiographic study Neurochemistry International 48 5 2006 358 366
    • (2006) Neurochemistry International , vol.48 , Issue.5 , pp. 358-366
    • Hasegawa, S.1    Nishi, K.2    Watanabe, A.3    Overstreet, D.H.4    Diksic, M.5
  • 20
    • 51349141187 scopus 로고    scopus 로고
    • Inhibition of peripheral TNF can block the malaise associated with CNS inflammatory diseases
    • Y. Jiang, R. Deacon, D.C. Anthony, and S.J. Campbell Inhibition of peripheral TNF can block the malaise associated with CNS inflammatory diseases Neurobiology of Disease 32 1 2008 125 132
    • (2008) Neurobiology of Disease , vol.32 , Issue.1 , pp. 125-132
    • Jiang, Y.1    Deacon, R.2    Anthony, D.C.3    Campbell, S.J.4
  • 24
    • 0026004558 scopus 로고
    • Antibodies against central nervous system tissue (anti-CNS) detected by ELISA and Western blotting: Marker antibodies for neuropsychiatric manifestations in connective tissue diseases
    • R. Klein, C. Richter, and P.A. Berg Antibodies against central nervous system tissue (anti-CNS) detected by ELISA and Western blotting: marker antibodies for neuropsychiatric manifestations in connective tissue diseases Autoimmunity 10 1991 133 144
    • (1991) Autoimmunity , vol.10 , pp. 133-144
    • Klein, R.1    Richter, C.2    Berg, P.A.3
  • 26
    • 0034047297 scopus 로고    scopus 로고
    • Effects of serotonin and serotonergic agonists and antagonists on the production of interferon-gamma and interleukin-10
    • M. Kubera, G. Kenis, E. Bosmans, S. Scharpé, and M. Maes Effects of serotonin and serotonergic agonists and antagonists on the production of interferon-gamma and interleukin-10 Neuropsychopharmacology 23 1 2000 89 98
    • (2000) Neuropsychopharmacology , vol.23 , Issue.1 , pp. 89-98
    • Kubera, M.1    Kenis, G.2    Bosmans, E.3    Scharpé, S.4    Maes, M.5
  • 27
    • 18844378658 scopus 로고    scopus 로고
    • Effects of serotonin and serotonergic agonists and antagonists on the production of tumor necrosis factor alpha and interleukin-6
    • M. Kubera, M. Maes, G. Kenis, Y.K. Kim, and W. Lasońn Effects of serotonin and serotonergic agonists and antagonists on the production of tumor necrosis factor alpha and interleukin-6 Psychiatry Research 134 3 2005 251 258
    • (2005) Psychiatry Research , vol.134 , Issue.3 , pp. 251-258
    • Kubera, M.1    Maes, M.2    Kenis, G.3    Kim, Y.K.4    Lasońn, W.5
  • 28
    • 79954621673 scopus 로고    scopus 로고
    • In animal models, psychosocial stress-induced (neuro)inflammation, apoptosis and reduced neurogenesis are associated to the onset of depression
    • M. Kubera, E. Obuchowicz, L. Goehler, J. Brzeszcz, and M. Maes In animal models, psychosocial stress-induced (neuro)inflammation, apoptosis and reduced neurogenesis are associated to the onset of depression Progress in Neuro-Psychopharmacology & Biological Psychiatry 35 3 2011 744 759
    • (2011) Progress in Neuro-Psychopharmacology & Biological Psychiatry , vol.35 , Issue.3 , pp. 744-759
    • Kubera, M.1    Obuchowicz, E.2    Goehler, L.3    Brzeszcz, J.4    Maes, M.5
  • 30
    • 0028796205 scopus 로고
    • Evidence for an immune response in major depression: A review and hypothesis
    • M. Maes Evidence for an immune response in major depression: a review and hypothesis Progress in Neuro-Psychopharmacology & Biological Psychiatry 19 1 1995 11 38
    • (1995) Progress in Neuro-Psychopharmacology & Biological Psychiatry , vol.19 , Issue.1 , pp. 11-38
    • Maes, M.1
  • 31
    • 48049084135 scopus 로고    scopus 로고
    • The cytokine hypothesis of depression: Inflammation, oxidative & nitrosative stress (IO&NS) and leaky gut as new targets for adjunctive treatments in depression
    • M. Maes The cytokine hypothesis of depression: inflammation, oxidative & nitrosative stress (IO&NS) and leaky gut as new targets for adjunctive treatments in depression Neuro Endocrinology Letters 29 3 2008 287 291
    • (2008) Neuro Endocrinology Letters , vol.29 , Issue.3 , pp. 287-291
    • Maes, M.1
  • 32
    • 77649248153 scopus 로고    scopus 로고
    • "Functional" or "psychosomatic" symptoms, e.g. A flu-like malaise, aches and pain and fatigue, are major features of major and in particular of melancholic depression
    • M. Maes "Functional" or "psychosomatic" symptoms, e.g. a flu-like malaise, aches and pain and fatigue, are major features of major and in particular of melancholic depression Neuro Endocrinology Letters 30 5 2009 564 573
    • (2009) Neuro Endocrinology Letters , vol.30 , Issue.5 , pp. 564-573
    • Maes, M.1
  • 33
    • 79954598830 scopus 로고    scopus 로고
    • Depression is an inflammatory disease, but cell-mediated immune activation is the key component of depression
    • M. Maes Depression is an inflammatory disease, but cell-mediated immune activation is the key component of depression Progress in Neuro- Psychopharmacology & Biological Psychiatry 35 3 2011 664 675
    • (2011) Progress in Neuro-Psychopharmacology & Biological Psychiatry , vol.35 , Issue.3 , pp. 664-675
    • Maes, M.1
  • 34
    • 0000587671 scopus 로고
    • The Serotonin Hypothesis of major depression. Selected Chapters on Mood Disorders. Psychopharmacology
    • F. Bloom, D. Kupfer, Raven Press
    • M. Maes, and H.Y. Meltzer The Serotonin Hypothesis of major depression. Selected Chapters on Mood Disorders. Psychopharmacology F. Bloom, D. Kupfer, The Fourth Generation of Progress 1995 Raven Press 933 944
    • (1995) The Fourth Generation of Progress , pp. 933-944
    • Maes, M.1    Meltzer, H.Y.2
  • 35
    • 0026099666 scopus 로고
    • Antiphospholipid, antinuclear, Epstein-Barr and cytomegalovirus antibodies, and soluble interleukin-2 receptors in depressive patients
    • M. Maes, E. Bosmans, E. Suy, C. Vandervorst, C. Dejonckheere, and J. Raus Antiphospholipid, antinuclear, Epstein-Barr and cytomegalovirus antibodies, and soluble interleukin-2 receptors in depressive patients Journal of Affective Disorders 21 2 1991 133 140
    • (1991) Journal of Affective Disorders , vol.21 , Issue.2 , pp. 133-140
    • Maes, M.1    Bosmans, E.2    Suy, E.3    Vandervorst, C.4    Dejonckheere, C.5    Raus, J.6
  • 36
    • 0026519357 scopus 로고
    • Evidence for a systemic immune activation during depression: Results of leukocyte enumeration by flow cytometry in conjunction with monoclonal antibody staining
    • M. Maes, J. Lambrechts, E. Bosmans, J. Jacobs, E. Suy, C. Vandervorst, C. de Jonckheere, B. Minner, and J. Raus Evidence for a systemic immune activation during depression: results of leukocyte enumeration by flow cytometry in conjunction with monoclonal antibody staining Psychological Medicine 22 1 1992 45 53
    • (1992) Psychological Medicine , vol.22 , Issue.1 , pp. 45-53
    • Maes, M.1    Lambrechts, J.2    Bosmans, E.3    Jacobs, J.4    Suy, E.5    Vandervorst, C.6    De Jonckheere, C.7    Minner, B.8    Raus, J.9
  • 37
    • 0026605463 scopus 로고
    • A significantly increased number and percentage of B cells in depressed subjects: Results of flow cytometric measurements
    • M. Maes, W.J. Stevens, L.S. DeClerck, C.H. Bridts, D. Peeters, C. Schotte, and P. Cosyns A significantly increased number and percentage of B cells in depressed subjects: results of flow cytometric measurements Journal of Affective Disorders 24 3 1992 127 134
    • (1992) Journal of Affective Disorders , vol.24 , Issue.3 , pp. 127-134
    • Maes, M.1    Stevens, W.J.2    Declerck, L.S.3    Bridts, C.H.4    Peeters, D.5    Schotte, C.6    Cosyns, P.7
  • 39
    • 0028670087 scopus 로고
    • Increased neopterin and interferon-gamma secretion and lower availability of L-tryptophan in major depression: Further evidence for an immune response
    • M. Maes, S. Scharpé, H.Y. Meltzer, G. Okayli, E. Bosmans, P. D'Hondt, B.V. Vanden Bossche, and P. Cosyns Increased neopterin and interferon-gamma secretion and lower availability of L-tryptophan in major depression: further evidence for an immune response Psychiatry Research 54 2 1994 143 160
    • (1994) Psychiatry Research , vol.54 , Issue.2 , pp. 143-160
    • Maes, M.1    Scharpé, S.2    Meltzer, H.Y.3    Okayli, G.4    Bosmans, E.5    D'Hondt, P.6    Vanden Bossche, B.V.7    Cosyns, P.8
  • 40
    • 37849046499 scopus 로고    scopus 로고
    • Increased serum IgM antibodies directed against phosphatidyl inositol (Pi) in chronic fatigue syndrome (CFS) and major depression: Evidence that an IgM-mediated immune response against Pi is one factor underpinning the comorbidity between both CFS and depression
    • M. Maes, I. Mihaylova, and J.C. Leunis Increased serum IgM antibodies directed against phosphatidyl inositol (Pi) in chronic fatigue syndrome (CFS) and major depression: evidence that an IgM-mediated immune response against Pi is one factor underpinning the comorbidity between both CFS and depression Neuro Endocrinology Letters 28 6 2007 861 867
    • (2007) Neuro Endocrinology Letters , vol.28 , Issue.6 , pp. 861-867
    • Maes, M.1    Mihaylova, I.2    Leunis, J.C.3
  • 41
    • 48049089358 scopus 로고    scopus 로고
    • An IgM-mediated immune response directed against nitro-bovine serum albumin (nitro-BSA) in chronic fatigue syndrome (CFS) and major depression: Evidence that nitrosative stress is another factor underpinning the comorbidity between major depression and CFS
    • M. Maes, I. Mihaylova, M. Kubera, and J.C. Leunis An IgM-mediated immune response directed against nitro-bovine serum albumin (nitro-BSA) in chronic fatigue syndrome (CFS) and major depression: evidence that nitrosative stress is another factor underpinning the comorbidity between major depression and CFS Neuro Endocrinology Letters 29 3 2008 313 319
    • (2008) Neuro Endocrinology Letters , vol.29 , Issue.3 , pp. 313-319
    • Maes, M.1    Mihaylova, I.2    Kubera, M.3    Leunis, J.C.4
  • 42
    • 57749179191 scopus 로고    scopus 로고
    • The inflammatory & neurodegenerative (I&ND) hypothesis of depression: Leads for future research and new drug developments in depression
    • M. Maes, R. Yirmyia, J. Noraberg, S. Brene, J. Hibbeln, G. Perini, M. Kubera, P. Bob, B. Lerer, and M. Maj The inflammatory & neurodegenerative (I&ND) hypothesis of depression: leads for future research and new drug developments in depression Metabolic Brain Disease 24 1 2009 27 53
    • (2009) Metabolic Brain Disease , vol.24 , Issue.1 , pp. 27-53
    • Maes, M.1    Yirmyia, R.2    Noraberg, J.3    Brene, S.4    Hibbeln, J.5    Perini, G.6    Kubera, M.7    Bob, P.8    Lerer, B.9    Maj, M.10
  • 43
    • 79954568978 scopus 로고    scopus 로고
    • A review on the oxidative and nitrosative stress (O&NS) pathways in major depression and their possible contribution to the (neuro)degenerative processes in that illness
    • M. Maes, P. Galecki, Y.S. Chang, and M. Berk A review on the oxidative and nitrosative stress (O&NS) pathways in major depression and their possible contribution to the (neuro)degenerative processes in that illness Progress in Neuro-Psychopharmacology & Biological Psychiatry 35 3 2011 676 692
    • (2011) Progress in Neuro-Psychopharmacology & Biological Psychiatry , vol.35 , Issue.3 , pp. 676-692
    • Maes, M.1    Galecki, P.2    Chang, Y.S.3    Berk, M.4
  • 45
    • 79954604454 scopus 로고    scopus 로고
    • The new '5-HT' hypothesis of depression: Cell-mediated immune activation induces indoleamine 2,3-dioxygenase, which leads to lower plasma tryptophan and an increased synthesis of detrimental tryptophan catabolites (TRYCATs), both of which contribute to the onset of depression
    • M. Maes, B.E. Leonard, A.M. Myint, M. Kubera, and R. Verkerk The new '5-HT' hypothesis of depression: cell-mediated immune activation induces indoleamine 2,3-dioxygenase, which leads to lower plasma tryptophan and an increased synthesis of detrimental tryptophan catabolites (TRYCATs), both of which contribute to the onset of depression Progress in Neuro-Psychopharmacology & Biological Psychiatry 35 3 2011 702 721
    • (2011) Progress in Neuro-Psychopharmacology & Biological Psychiatry , vol.35 , Issue.3 , pp. 702-721
    • Maes, M.1    Leonard, B.E.2    Myint, A.M.3    Kubera, M.4    Verkerk, R.5
  • 46
    • 80055020217 scopus 로고    scopus 로고
    • IgM-mediated autoimmune responses directed against multiple neoepitopes in depression: New pathways that underpin the inflammatory and neuroprogressive pathophysiology
    • M. Maes, I. Mihaylova, M. Kubera, J.C. Leunis, and M. Geffard IgM-mediated autoimmune responses directed against multiple neoepitopes in depression: New pathways that underpin the inflammatory and neuroprogressive pathophysiology Journal of Affective Disorders 135 1-3 2011 414 418
    • (2011) Journal of Affective Disorders , vol.135 , Issue.13 , pp. 414-418
    • Maes, M.1    Mihaylova, I.2    Kubera, M.3    Leunis, J.C.4    Geffard, M.5
  • 48
    • 50249099851 scopus 로고    scopus 로고
    • The effects of experimentally lowered serotonin function on emotional information processing and memory in remitted depressed patients
    • W. Merens, L. Booij, P.J. Haffmans, and A. van der Does The effects of experimentally lowered serotonin function on emotional information processing and memory in remitted depressed patients Journal of Psychopharmacology 22 6 2008 653 662
    • (2008) Journal of Psychopharmacology , vol.22 , Issue.6 , pp. 653-662
    • Merens, W.1    Booij, L.2    Haffmans, P.J.3    Van Der Does, A.4
  • 50
    • 0028153944 scopus 로고
    • Enhancement of hydrogen peroxide-induced luminol-dependent chemiluminescence by neopterin depends on the presence of iron chelator complexes
    • C. Murr, D. Fuchs, W. Gössler, A. Hausen, G. Reibnegger, E.R. Werner, G. Werner-Felmayer, H. Esterbauer, and H. Wachter Enhancement of hydrogen peroxide-induced luminol-dependent chemiluminescence by neopterin depends on the presence of iron chelator complexes FEBS Letters 338 2 1994 223 226
    • (1994) FEBS Letters , vol.338 , Issue.2 , pp. 223-226
    • Murr, C.1    Fuchs, D.2    Gössler, W.3    Hausen, A.4    Reibnegger, G.5    Werner, E.R.6    Werner-Felmayer, G.7    Esterbauer, H.8    Wachter, H.9
  • 51
    • 0033746310 scopus 로고    scopus 로고
    • Antioxidative and free radical scavenging activities of pineal indoles
    • T.B. Ng, F. Liu, and L. Zhao Antioxidative and free radical scavenging activities of pineal indoles Journal of Neural Transmission 107 11 1999 1243 1251
    • (1999) Journal of Neural Transmission , vol.107 , Issue.11 , pp. 1243-1251
    • Ng, T.B.1    Liu, F.2    Zhao, L.3
  • 52
    • 77949867445 scopus 로고    scopus 로고
    • A functional serotonin transporter gene polymorphism and depressive effects associated with interferon-alpha treatment
    • HALT-C Trial Group
    • A. Pierucci-Lagha, J. Covault, H.L. Bonkovsky, R. Feinn, C. Abreu, R.K. Sterling, R.J. Fontana, H.R. Kranzler HALT-C Trial Group A functional serotonin transporter gene polymorphism and depressive effects associated with interferon-alpha treatment Psychosomatics 51 2 2010 137 148
    • (2010) Psychosomatics , vol.51 , Issue.2 , pp. 137-148
    • Pierucci-Lagha, A.1    Covault, J.2    Bonkovsky, H.L.3    Feinn, R.4    Abreu, C.5    Sterling, R.K.6    Fontana, R.J.7    Kranzler, H.R.8
  • 53
    • 0034096128 scopus 로고    scopus 로고
    • Changes in the platelet intracellular calcium response to serotonin in patients with major depression treated with electroconvulsive therapy: State or trait marker status
    • H. Plein, and M. Berk Changes in the platelet intracellular calcium response to serotonin in patients with major depression treated with electroconvulsive therapy: state or trait marker status International Clinical Psychopharmacology 15 2 2000 93 98
    • (2000) International Clinical Psychopharmacology , vol.15 , Issue.2 , pp. 93-98
    • Plein, H.1    Berk, M.2
  • 54
    • 0033579321 scopus 로고    scopus 로고
    • Augmented platelet calcium uptake in response to serotonin stimulation in patients with major depression measured using Mn2 + influx and 45Ca2 + uptake
    • H. Plein, M. Berk, S. Eppel, and N. Butkow Augmented platelet calcium uptake in response to serotonin stimulation in patients with major depression measured using Mn2 + influx and 45Ca2 + uptake Life Sciences 66 5 2000 425 431
    • (2000) Life Sciences , vol.66 , Issue.5 , pp. 425-431
    • Plein, H.1    Berk, M.2    Eppel, S.3    Butkow, N.4
  • 55
    • 34548016732 scopus 로고    scopus 로고
    • Kindling and sensitization as models for affective episode recurrence, cyclicity, and tolerance phenomena
    • R.M. Post Kindling and sensitization as models for affective episode recurrence, cyclicity, and tolerance phenomena Neuroscience and Biobehavioral Reviews 31 6 2007 858 873
    • (2007) Neuroscience and Biobehavioral Reviews , vol.31 , Issue.6 , pp. 858-873
    • Post, R.M.1
  • 56
    • 0029562828 scopus 로고
    • Induction of inducible nitric oxide synthase expression by neopterin in vascular smooth muscle cells
    • W. Schobersberger, G. Hoffmann, J. Grote, H. Wachter, and D. Fuchs Induction of inducible nitric oxide synthase expression by neopterin in vascular smooth muscle cells FEBS Letters 377 3 1995 461 464
    • (1995) FEBS Letters , vol.377 , Issue.3 , pp. 461-464
    • Schobersberger, W.1    Hoffmann, G.2    Grote, J.3    Wachter, H.4    Fuchs, D.5
  • 59
    • 79954613032 scopus 로고    scopus 로고
    • Cytokines mediated inflammation and decreased neurogenesis in animal models of depression
    • C. Song, and H. Wang Cytokines mediated inflammation and decreased neurogenesis in animal models of depression Progress in Neuro-Psychopharmacology & Biological Psychiatry 35 3 2011 760 768
    • (2011) Progress in Neuro-Psychopharmacology & Biological Psychiatry , vol.35 , Issue.3 , pp. 760-768
    • Song, C.1    Wang, H.2
  • 62
    • 50249150354 scopus 로고    scopus 로고
    • Interferon-alpha-induced serotonin uptake in Jurkat T cells via mitogen-activated protein kinase and transcriptional regulation of the serotonin transporter
    • C.W. Tsao, Y.S. Lin, J.T. Cheng, C.F. Lin, H.T. Wu, S.R. Wu, and W.H. Tsai Interferon-alpha-induced serotonin uptake in Jurkat T cells via mitogen-activated protein kinase and transcriptional regulation of the serotonin transporter Journal of Psychopharmacology 22 7 2008 753 760
    • (2008) Journal of Psychopharmacology , vol.22 , Issue.7 , pp. 753-760
    • Tsao, C.W.1    Lin, Y.S.2    Cheng, J.T.3    Lin, C.F.4    Wu, H.T.5    Wu, S.R.6    Tsai, W.H.7
  • 63
    • 0035054352 scopus 로고    scopus 로고
    • The effects of tryptophan depletion on mood and psychiatric symptoms
    • A.J. Van der Does The effects of tryptophan depletion on mood and psychiatric symptoms Journal of Affective Disorders 64 2-3 2001 107 119
    • (2001) Journal of Affective Disorders , vol.64 , Issue.23 , pp. 107-119
    • Van Der Does, A.J.1
  • 65
    • 0025970896 scopus 로고
    • Interactions of 5-hydroxytryptamine with oxidative enzymes
    • M.Z. Wrona, and G. Dryhurst Interactions of 5-hydroxytryptamine with oxidative enzymes Biochemical Pharmacology 41 8 1991 1145 1162
    • (1991) Biochemical Pharmacology , vol.41 , Issue.8 , pp. 1145-1162
    • Wrona, M.Z.1    Dryhurst, G.2
  • 68
    • 33748808678 scopus 로고    scopus 로고
    • The proinflammatory cytokines interleukin-1beta and tumor necrosis factor-alpha activate serotonin transporters
    • C.B. Zhu, R.D. Blakely, and W.A. Hewlett The proinflammatory cytokines interleukin-1beta and tumor necrosis factor-alpha activate serotonin transporters Neuropsychopharmacology 31 10 2006 2121 2131
    • (2006) Neuropsychopharmacology , vol.31 , Issue.10 , pp. 2121-2131
    • Zhu, C.B.1    Blakely, R.D.2    Hewlett, W.A.3
  • 69
    • 78149466027 scopus 로고    scopus 로고
    • Interleukin-1 receptor activation by systemic lipopolysaccharide induces behavioral despair linked to MAPK regulation of CNS serotonin transporters
    • C.B. Zhu, K.M. Lindler, A.W. Owens, L.C. Daws, R.D. Blakely, and W.A. Hewlett Interleukin-1 receptor activation by systemic lipopolysaccharide induces behavioral despair linked to MAPK regulation of CNS serotonin transporters Neuropsychopharmacology 35 13 2010 2510 2520
    • (2010) Neuropsychopharmacology , vol.35 , Issue.13 , pp. 2510-2520
    • Zhu, C.B.1    Lindler, K.M.2    Owens, A.W.3    Daws, L.C.4    Blakely, R.D.5    Hewlett, W.A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.