메뉴 건너뛰기




Volumn 60, Issue 1, 2014, Pages 114-124

C5a/C5aR pathway is essential for the pathogenesis of murine viral fulminant hepatitis by way of potentiating Fgl2/fibroleukin expression

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENT COMPONENT C5A; COMPLEMENT COMPONENT C5A RECEPTOR; FIBRINOGEN LIKE PROTEIN 2; FIBROLEUKIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN; SYNAPTOPHYSIN; UNCLASSIFIED DRUG;

EID: 84903266513     PISSN: 02709139     EISSN: 15273350     Source Type: Journal    
DOI: 10.1002/hep.27114     Document Type: Article
Times cited : (39)

References (34)
  • 1
    • 0027919071 scopus 로고
    • Acute liver failure
    • Lee WM. Acute liver failure. N Engl J Med 1993;329:1862-1872.
    • (1993) N Engl J Med , vol.329 , pp. 1862-1872
    • Lee, W.M.1
  • 3
    • 0021878468 scopus 로고
    • Acute and chronic changes in the microcirculation of the liver in inbred strains of mice following infection with mouse hepatitis virus type 3
    • MacPhee PJ, Dindzans VJ, Fung LS, Levy GA. Acute and chronic changes in the microcirculation of the liver in inbred strains of mice following infection with mouse hepatitis virus type 3. Hepatology 1985;5:649-660.
    • (1985) Hepatology , vol.5 , pp. 649-660
    • MacPhee, P.J.1    Dindzans, V.J.2    Fung, L.S.3    Levy, G.A.4
  • 4
    • 0025347074 scopus 로고
    • Deficiency of the murine fifth complement component (C5). A 2-base pair gene deletion in a 5'-exon
    • Wetsel RA, Fleischer DT, Haviland DL. Deficiency of the murine fifth complement component (C5). A 2-base pair gene deletion in a 5'-exon. J Biol Chem 1990; 265:2435-2440.
    • (1990) J Biol Chem , vol.265 , pp. 2435-2440
    • Wetsel, R.A.1    Fleischer, D.T.2    Haviland, D.L.3
  • 5
    • 5944254200 scopus 로고    scopus 로고
    • Identification of complement factor 5 as a susceptibility locus for experimental allergic asthma
    • Karp CL, Grupe A, Schadt E, Ewart SL, Keane-Moore M, Cuomo PJ, et al. Identification of complement factor 5 as a susceptibility locus for experimental allergic asthma. Nat Immunol 2000;1:221-226.
    • (2000) Nat Immunol , vol.1 , pp. 221-226
    • Karp, C.L.1    Grupe, A.2    Schadt, E.3    Ewart, S.L.4    Keane-Moore, M.5    Cuomo, P.J.6
  • 7
    • 23044477984 scopus 로고    scopus 로고
    • Complement factor 5 is a quantitative trait genethat modifies liver fibrogenesis in mice and humans
    • Hillebrandt S, Wasmuth HE, Weiskirchen R, Hellerbrand C, Keppeler H, Werth A, et al. Complement factor 5 is a quantitative trait genethat modifies liver fibrogenesis in mice and humans. Nat Genet 2005;37:835-843.
    • (2005) Nat Genet , vol.37 , pp. 835-843
    • Hillebrandt, S.1    Wasmuth, H.E.2    Weiskirchen, R.3    Hellerbrand, C.4    Keppeler, H.5    Werth, A.6
  • 8
    • 17644388462 scopus 로고    scopus 로고
    • Role of C5a in inflammatory responses
    • Guo RF, Ward PA. Role of C5a in inflammatory responses. Annu Rev Immunol 2005;23:821-852.
    • (2005) Annu Rev Immunol , vol.23 , pp. 821-852
    • Guo, R.F.1    Ward, P.A.2
  • 10
    • 0027052745 scopus 로고
    • Cloning and functional expression of the canine anaphylatoxin C5a receptor. Evidence for high interspecies variability
    • Perret JJ, Raspe E, Vassart G, Parmentier M. Cloning and functional expression of the canine anaphylatoxin C5a receptor. Evidence for high interspecies variability. Biochem J 1992;288:911-917.
    • (1992) Biochem J , vol.288 , pp. 911-917
    • Perret, J.J.1    Raspe, E.2    Vassart, G.3    Parmentier, M.4
  • 11
    • 0036510770 scopus 로고    scopus 로고
    • The orphan receptor C5L2 has high affinity binding sites for complement fragments C5a and C5a des-Arg (74)
    • Cain SA, Monk PN. The orphan receptor C5L2 has high affinity binding sites for complement fragments C5a and C5a des-Arg (74). J Biol Chem 2002;277:7165-7169.
    • (2002) J Biol Chem , vol.277 , pp. 7165-7169
    • Cain, S.A.1    Monk, P.N.2
  • 12
    • 33947110020 scopus 로고    scopus 로고
    • C5L2 is critical for the biological activities of the anaphylatoxins C5a and C3a
    • Chen NJ, Mirtsos C, Suh D, Lu YC, Lin WJ, McKerlie C, et al. C5L2 is critical for the biological activities of the anaphylatoxins C5a and C3a. Nature 2007;446:203-207.
    • (2007) Nature , vol.446 , pp. 203-207
    • Chen, N.J.1    Mirtsos, C.2    Suh, D.3    Lu, Y.C.4    Lin, W.J.5    McKerlie, C.6
  • 13
    • 77956057326 scopus 로고    scopus 로고
    • The harmful role of C5a on innate immunity in sepsis
    • Ward PA. The harmful role of C5a on innate immunity in sepsis. J Innate Immun 2010;2:439-445.
    • (2010) J Innate Immun , vol.2 , pp. 439-445
    • Ward, P.A.1
  • 16
    • 0023518436 scopus 로고
    • 16, 16 Dimethyl prostaglandin E2 prevents the development of fulminant hepatitis and blocks the induction of monocyte/macrophage procoagulant activity after murine hepatitis virus strain 3 infection
    • Abecassis M, Falk JA, Makowka L, Dindzans VJ, Falk RE, Levy GA. 16, 16 Dimethyl prostaglandin E2 prevents the development of fulminant hepatitis and blocks the induction of monocyte/macrophage procoagulant activity after murine hepatitis virus strain 3 infection. J Clin Invest 1987;80:881-889.
    • (1987) J Clin Invest , vol.80 , pp. 881-889
    • Abecassis, M.1    Falk, J.A.2    Makowka, L.3    Dindzans, V.J.4    Falk, R.E.5    Levy, G.A.6
  • 17
    • 84880253499 scopus 로고    scopus 로고
    • Expression of B and T lymphocyte attenuator (BTLA) in macrophages contributes to the fulminant hepatitis caused by murine hepatitis virus strain-3
    • Yang C, Chen Y, Guo G, Li H, Cao D, Xu H, et al. Expression of B and T lymphocyte attenuator (BTLA) in macrophages contributes to the fulminant hepatitis caused by murine hepatitis virus strain-3. Gut 2013;62:1204-1213.
    • (2013) Gut , vol.62 , pp. 1204-1213
    • Yang, C.1    Chen, Y.2    Guo, G.3    Li, H.4    Cao, D.5    Xu, H.6
  • 18
    • 0026661004 scopus 로고
    • Monoclonal antiprothrombinase (3D4.3) prevents mortality from murine hepatitis virus (MHV-3) infection
    • Li C, Fung LS, Chung S, Crow A, Myers-Mason N, Phillips MJ, et al. Monoclonal antiprothrombinase (3D4.3) prevents mortality from murine hepatitis virus (MHV-3) infection. J Exp Med 1992;176:689-697.
    • (1992) J Exp Med , vol.176 , pp. 689-697
    • Li, C.1    Fung, L.S.2    Chung, S.3    Crow, A.4    Myers-Mason, N.5    Phillips, M.J.6
  • 19
    • 0030807894 scopus 로고    scopus 로고
    • Fulminant hepatic failure in murine hepatitis virus strain 3 infection: tissue-specific expression of a novel Fgl2 prothrombinase
    • Ding JW, Ning Q, Liu MF, Lai A, Leibowitz J, Peltekian KM, et al. Fulminant hepatic failure in murine hepatitis virus strain 3 infection: tissue-specific expression of a novel Fgl2 prothrombinase. J Virol 1997;71:9223-9230.
    • (1997) J Virol , vol.71 , pp. 9223-9230
    • Ding, J.W.1    Ning, Q.2    Liu, M.F.3    Lai, A.4    Leibowitz, J.5    Peltekian, K.M.6
  • 20
    • 0038182553 scopus 로고    scopus 로고
    • Induction of prothrombinase Fgl2 by the nucleocapsid protein of virulent mouse hepatitis virus is dependent on host hepatic nuclear factor-4 alpha
    • Ning Q, Lakatoo S, Liu M, Yang W, Wang Z, Phillips MJ, et al. Induction of prothrombinase Fgl2 by the nucleocapsid protein of virulent mouse hepatitis virus is dependent on host hepatic nuclear factor-4 alpha. J Biol Chem 2003;278:15541-15549.
    • (2003) J Biol Chem , vol.278 , pp. 15541-15549
    • Ning, Q.1    Lakatoo, S.2    Liu, M.3    Yang, W.4    Wang, Z.5    Phillips, M.J.6
  • 21
    • 85047694360 scopus 로고    scopus 로고
    • The Fgl2/fibroleukin prothrombinase contributes to immunologically mediated thrombosis in experimental and human viral hepatitis
    • Marsden PA, Ning Q, Fung LS, Luo X, Chen Y, Mendicino M, et al. The Fgl2/fibroleukin prothrombinase contributes to immunologically mediated thrombosis in experimental and human viral hepatitis. J Clin Invest 2003;112:58-66.
    • (2003) J Clin Invest , vol.112 , pp. 58-66
    • Marsden, P.A.1    Ning, Q.2    Fung, L.S.3    Luo, X.4    Chen, Y.5    Mendicino, M.6
  • 22
    • 0033519733 scopus 로고    scopus 로고
    • Low-molecular-weight peptidic and cyclic antagonists of the receptor for the complement factor C5a
    • Finch AM, Wong AK, Paczkowski NJ, Wadi SK, Craik DJ, Fairlie DP, et al. Low-molecular-weight peptidic and cyclic antagonists of the receptor for the complement factor C5a. J Med Chem 1999;42:1965-1974.
    • (1999) J Med Chem , vol.42 , pp. 1965-1974
    • Finch, A.M.1    Wong, A.K.2    Paczkowski, N.J.3    Wadi, S.K.4    Craik, D.J.5    Fairlie, D.P.6
  • 23
    • 0033610804 scopus 로고    scopus 로고
    • Murine hepatitis virus strain 3 induces the macrophage prothrombinase fgl-2 through p38 mitogen-activated protein kinase activation
    • McGilvray ID, Lu Z, Wei AC, Dackiw AP, Marshall JC, Kapus A, et al. Murine hepatitis virus strain 3 induces the macrophage prothrombinase fgl-2 through p38 mitogen-activated protein kinase activation. J. Biol Chem 1998;273:32222-32229.
    • (1998) J. Biol Chem , vol.273 , pp. 32222-32229
    • McGilvray, I.D.1    Lu, Z.2    Wei, A.C.3    Dackiw, A.P.4    Marshall, J.C.5    Kapus, A.6
  • 24
    • 0030941650 scopus 로고    scopus 로고
    • Anaphylatoxin C5a receptor mRNA is strongly expressed in Kupffer and stellate cells and weakly in sinusoidal endothelial cells but not in hepatocytes of normal rat liver
    • Schieferdecker HL, Rothermel E, Timmermann A, Gotze O, Jungermann K. Anaphylatoxin C5a receptor mRNA is strongly expressed in Kupffer and stellate cells and weakly in sinusoidal endothelial cells but not in hepatocytes of normal rat liver. FEBS Lett 1997;406:305-309.
    • (1997) FEBS Lett , vol.406 , pp. 305-309
    • Schieferdecker, H.L.1    Rothermel, E.2    Timmermann, A.3    Gotze, O.4    Jungermann, K.5
  • 27
    • 0029034774 scopus 로고
    • Inhibition of MAP kinase kinase blocks the differentiation of PC-12 cells induced by nerve growth factor
    • Pang L, Sawada T, Decker SJ, Saltiel AR. Inhibition of MAP kinase kinase blocks the differentiation of PC-12 cells induced by nerve growth factor. J Biol Chem 1995;270:13585-13588.
    • (1995) J Biol Chem , vol.270 , pp. 13585-13588
    • Pang, L.1    Sawada, T.2    Decker, S.J.3    Saltiel, A.R.4
  • 29
    • 0028988138 scopus 로고
    • SB 203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin-1
    • Cuenda A, Rouse J, Doza YN, Meier R, Cohen P, Gallagher TF, et al. SB 203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin-1. FEBS Lett 1995;364:229-233.
    • (1995) FEBS Lett , vol.364 , pp. 229-233
    • Cuenda, A.1    Rouse, J.2    Doza, Y.N.3    Meier, R.4    Cohen, P.5    Gallagher, T.F.6
  • 30
    • 0031587929 scopus 로고    scopus 로고
    • Novel homologues of CSBP/p38 MAP kinase: activation, substrate specificity and sensitivity to inhibition by pyridinyl imidazoles
    • Kumar S, McDonnell PC, Gum RJ, Hand AT, Lee JC, Young PR. Novel homologues of CSBP/p38 MAP kinase: activation, substrate specificity and sensitivity to inhibition by pyridinyl imidazoles. Biochem Biophys Res Commun 1997;235:533-538.
    • (1997) Biochem Biophys Res Commun , vol.235 , pp. 533-538
    • Kumar, S.1    McDonnell, P.C.2    Gum, R.J.3    Hand, A.T.4    Lee, J.C.5    Young, P.R.6
  • 31
    • 34249111166 scopus 로고    scopus 로고
    • The priming effect of C5a on monocytes is predominantly mediated by the p38 MAPK pathway
    • Schaeffer V, Cuschieri J, Garcia I, Knoll M, Billgren J, Jelacic S, et al. The priming effect of C5a on monocytes is predominantly mediated by the p38 MAPK pathway. Shock 2007;27:623-630.
    • (2007) Shock , vol.27 , pp. 623-630
    • Schaeffer, V.1    Cuschieri, J.2    Garcia, I.3    Knoll, M.4    Billgren, J.5    Jelacic, S.6
  • 32
    • 4143060419 scopus 로고    scopus 로고
    • C5a differentially stimulates the ERK1/2 and p38 MAPK phosphorylation through independent signaling pathways to induced chemotactic migration in RAW264.7 macrophages
    • Chiou WF, Tsai HR, Yang LM, Tsai WJ. C5a differentially stimulates the ERK1/2 and p38 MAPK phosphorylation through independent signaling pathways to induced chemotactic migration in RAW264.7 macrophages. Int Immunopharmacol 2004;4:1329-1341.
    • (2004) Int Immunopharmacol , vol.4 , pp. 1329-1341
    • Chiou, W.F.1    Tsai, H.R.2    Yang, L.M.3    Tsai, W.J.4
  • 33
    • 23844434887 scopus 로고    scopus 로고
    • G (i)-protein-dependent inhibition of IL-12 production is mediated by activation of the phosphatidylinositol 3-kinase-protein 3 kinase B/Akt pathway and JNK
    • la Sala A, Gadina M, Kelsall BL. G (i)-protein-dependent inhibition of IL-12 production is mediated by activation of the phosphatidylinositol 3-kinase-protein 3 kinase B/Akt pathway and JNK. J Immunol 2005;175:2994-2999.
    • (2005) J Immunol , vol.175 , pp. 2994-2999
    • la Sala, A.1    Gadina, M.2    Kelsall, B.L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.