ATF6 mediates a pro-inflammatory synergy between ER stress and TLR activation in the pathogenesis of liver ischemia-reperfusion injury

American Journal of Transplantation

Volumn 14, Issue 7, 2014, Pages 1552-1561

  Rao, J ^a,b   Yue, S ^a   Fu, Y ^a   Zhu, J ^a,c   Wang, X ^b   Busuttil, R W ^a   Kupiec Weglinski, J W ^a   Lu, L ^b   Zhai, Y ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b NANJING MEDICAL UNIVERSITY   (China)

^c SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

ATF6; ER stress; ischemia reperfusion injury; Kupffer cells; TLR activation

Indexed keywords

4 PHENYLBUTYRIC ACID; ACTIVATING TRANSCRIPTION FACTOR 6; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; SMALL INTERFERING RNA; TOLL LIKE RECEPTOR 4; ATF6 PROTEIN, MOUSE; AUTACOID; MESSENGER RNA; PROTEIN KINASE B; TOLL LIKE RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL ISOLATION; CYTOKINE PRODUCTION; ENDOPLASMIC RETICULUM STRESS; IMMUNE RESPONSE; IMMUNOCOMPETENT CELL; IN VITRO STUDY; IN VIVO STUDY; INNATE IMMUNITY; KUPFFER CELL; LIVER CELL; LIVER ISCHEMIA; MACROPHAGE CULTURE; MALE; METABOLIC STRESS; MOUSE; NONHUMAN; PRIORITY JOURNAL; REPERFUSION INJURY; ANIMAL; ANTAGONISTS AND INHIBITORS; C57BL MOUSE; CELL CULTURE; ENZYME LINKED IMMUNOSORBENT ASSAY; GENETICS; IMMUNOLOGY; ISCHEMIA; MACROPHAGE; METABOLISM; PATHOLOGY; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ACTIVATING TRANSCRIPTION FACTOR 6; ANIMALS; BLOTTING, WESTERN; CELLS, CULTURED; ENDOPLASMIC RETICULUM STRESS; ENZYME-LINKED IMMUNOSORBENT ASSAY; INFLAMMATION MEDIATORS; ISCHEMIA; KUPFFER CELLS; MACROPHAGES; MALE; MICE; MICE, INBRED C57BL; NF-KAPPA B; PROTO-ONCOGENE PROTEINS C-AKT; REAL-TIME POLYMERASE CHAIN REACTION; REPERFUSION INJURY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTORS;

EID: 84903169952     PISSN: 16006135     EISSN: 16006143     Source Type: Journal    
DOI: 10.1111/ajt.12711     Document Type: Article

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