-
2
-
-
0025873435
-
Cloning and expression of a novel neurotrophin, NT-7, from carp
-
Klein R, Nanduri V, Jing SA, et al. Cloning and expression of a novel neurotrophin, NT-7, from carp. Cell 1991;66:395-403
-
(1991)
Cell
, vol.66
, pp. 395-403
-
-
Klein, R.1
Nanduri, V.2
Jing, S.A.3
-
3
-
-
0028019114
-
Neurotrophin-6 is a new member of the nerve growth factor family
-
DOI 10.1038/372266a0
-
Gotz R, Koster R, Winkler C, Raulf F. Neurotrophin-6 is a new member of the nerve growth factor family. Nature 1994;372:266-9 (Pubitemid 24352448)
-
(1994)
Nature
, vol.372
, Issue.6503
, pp. 266-269
-
-
Gotz, R.1
Koster, R.2
Winkler, C.3
Raulf, F.4
Lottspeich, F.5
Schartl, M.6
Thoenen, H.7
-
4
-
-
0026545268
-
Mammalian neurotrophin-4: Structure, chromosomal localisation, tissue distribution and receptor specificity
-
Ip NY, Ibanez CF, Nye SH, McClain J. Mammalian neurotrophin-4: structure, chromosomal localisation, tissue distribution and receptor specificity. Proc Natl Acad Sci USA 1992;89:3060-4
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 3060-3064
-
-
Ip, N.Y.1
Ibanez, C.F.2
Nye, S.H.3
McClain, J.4
-
5
-
-
0025944524
-
TrkC, a new member of the trk family of tyrosine protein kinases, is a receptor for neurotrophin-3
-
Lamballe F, Klein R, Barbacid M. TrkC, a new member of the trk family of tyrosine protein kinases, is a receptor for neurotrophin-3. Cell 1991;66:967-79 (Pubitemid 121001730)
-
(1991)
Cell
, vol.66
, Issue.5
, pp. 967-979
-
-
Lamballe, F.1
Klein, R.2
Barbacid, M.3
-
6
-
-
2342591455
-
The discovery of receptor tyrosine kinases: Targets for cancer therapy
-
Gschwind A, Fischer OM, Ullrich A. The discovery of receptor kinases: targets for cancer therapy. Nat Rev Cancer 2004;4:361-70 (Pubitemid 38579482)
-
(2004)
Nature Reviews Cancer
, vol.4
, Issue.5
, pp. 361-370
-
-
Gschwind, A.1
Fischer, O.M.2
Ullrich, A.3
-
7
-
-
70349659954
-
On Trk-The TrkB signal transduction pathway is an increasingly important target in cancer biology
-
Thiele CJ, Li Z, McKee AE. On Trk-The TrkB signal transduction pathway is an increasingly important target in cancer biology. Clin Cancer Res 2009;15:5962-7
-
(2009)
Clin Cancer Res
, vol.15
, pp. 5962-5967
-
-
Thiele, C.J.1
Li, Z.2
McKee, A.E.3
-
9
-
-
0033815648
-
Rational basis for Trk inhibition therapy for prostate cancer
-
Weeraratna AT, Arnold JT, George DJ. Rational basis for Trk inhibition therapy for prostate cancer. Prostate 2000;45:140-8
-
(2000)
Prostate
, vol.45
, pp. 140-148
-
-
Weeraratna, A.T.1
Arnold, J.T.2
George, D.J.3
-
10
-
-
84869884311
-
Neurotrophins and their receptors in breast cancer
-
Hondermarck H. Neurotrophins and their receptors in breast cancer. Cytokine Growth Factor Rev 2012;23:357-65
-
(2012)
Cytokine Growth Factor Rev
, vol.23
, pp. 357-365
-
-
Hondermarck, H.1
-
11
-
-
19944429463
-
Overexpression of tropomysin-related kinase B in metastatic human pancreatic cancer cells
-
Sclabas GM, Fujioka S, Schmidt C. Overexpression of tropomyosin-related kinase B in metastatic human pancreatic cancer cells. Clin Cancer Res 2005;11:440-9 (Pubitemid 40116865)
-
(2005)
Clinical Cancer Research
, vol.11
, Issue.2
, pp. 440-449
-
-
Sclabas, G.M.1
Fujioka, S.2
Schmidt, C.3
Li, Z.4
Frederick, W.A.I.5
Yang, W.6
Yokoi, K.7
Evans, D.B.8
Abbruzzese, J.L.9
Hess, K.R.10
Zhang, W.11
Fidler, I.J.12
Chiao, P.J.13
-
12
-
-
0031738824
-
Congenital mesoblastic nephroma t(12;15) is associated with ETV6-NTRK3 gene fusion: Cytogenetic and molecular relationship to congenital (infantile) fibrosarcoma
-
Rubin BP, Chen CJ, Morgan TW, et al. Congenital mesoblastic nephroma t(12;15) is associated with ETV6-NTRK3 gene fusion: cytogenetic and molecular relationship to congenital (infantile) fibrosarcoma. Am J Pathol 1998;153:1451-8 (Pubitemid 28509901)
-
(1998)
American Journal of Pathology
, vol.153
, Issue.5
, pp. 1451-1458
-
-
Rubin, B.P.1
Chen, C.-J.2
Morgan, T.W.3
Xiao, S.4
Grier, H.E.5
Kozakewich, H.P.6
Perez-Atayde, A.R.7
Fletcher, J.A.8
-
13
-
-
1842841901
-
ETV6-NTRK3 - Trk-ing the primary event in human secretory breast cancer
-
DOI 10.1016/S1535-6108(02)00184-8
-
Euhus DM, Timmons CF, Tomlinson GE. ETV6-NTRK3-Trk-ing the primary event in human secretory breast cancer. Cancer Cell 2002;2:347-8 (Pubitemid 41039098)
-
(2002)
Cancer Cell
, vol.2
, Issue.5
, pp. 347-348
-
-
Euhus, D.M.1
Timmons, C.F.2
Tomlinson, G.E.3
-
14
-
-
30144437331
-
Oncogenic rearrangements of the NTRK1/NGF receptor
-
DOI 10.1016/j.canlet.2005.07.043, PII S0304383505008244
-
Pierotti MA, Greco A. Oncogenic rearrangements of the NTRK1/NGF receptor. Cancer Lett 2006;232:90-8 (Pubitemid 43053936)
-
(2006)
Cancer Letters
, vol.232
, Issue.1
, pp. 90-98
-
-
Pierotti, M.A.1
Greco, A.2
-
15
-
-
77950939830
-
Rearrangements of NTRK1 gene in papillary thyroid carcinoma
-
Greco A, Miranda C, Pierotti MA. Rearrangements of NTRK1 gene in papillary thyroid carcinoma. Mol Cell Endocrinol 2010;321:44-9
-
(2010)
Mol Cell Endocrinol
, vol.321
, pp. 44-49
-
-
Greco, A.1
Miranda, C.2
Pierotti, M.A.3
-
16
-
-
84887445619
-
Oncogenic and drug-sensitive NTRK1 rearrangements in lung cancer
-
Vaishnavi A, Capelletti M, Le AT, et al. Oncogenic and drug-sensitive NTRK1 rearrangements in lung cancer. Nat Med 2013;19:1469-72
-
(2013)
Nat Med
, vol.19
, pp. 1469-1472
-
-
Vaishnavi, A.1
Capelletti Le M, A.T.2
-
17
-
-
84892586739
-
Crizotinib: A review of its use in the treatment of anaplastic lymphoma kinase-positive, advanced non-small cell lung cancer
-
Frampton JE. Crizotinib: a review of its use in the treatment of anaplastic lymphoma kinase-positive, advanced non-small cell lung cancer. Drugs 2013;73:2031-51
-
(2013)
Drugs
, vol.73
, pp. 2031-2051
-
-
Frampton, J.E.1
-
18
-
-
15844369925
-
Mutations in the TRKA/NGF receptor gene in patients with congenital insensitivity to pain with anhidrosis
-
DOI 10.1038/ng0896-485
-
Indo Y, Tsuruta M, Hayashida Y. Mutations in the TrkA/NGF receptor gene in patients with congenital insensitivity to pain with anhidrosis. Nat Genet 1996;13:485-8 (Pubitemid 26256627)
-
(1996)
Nature Genetics
, vol.13
, Issue.4
, pp. 485-488
-
-
Indo, Y.1
Tsuruta, M.2
Hayashida, Y.3
Karim, M.A.4
Ohta, K.5
Kawano, T.6
Mitsubuchi, H.7
Tonoki, H.8
Awaya, Y.9
Matsuda, I.10
-
19
-
-
77957934893
-
Tanezumab for the treatment of pain from Osteoarthritis of the knee
-
Lane NE, Schnitzer TJ, Birbara CA, et al. Tanezumab for the treatment of pain from Osteoarthritis of the knee. N Engl J Med 2010;363:1521-31
-
(2010)
N Engl J Med
, vol.363
, pp. 1521-1531
-
-
Lane, N.E.1
Schnitzer, T.J.2
Birbara, C.A.3
-
20
-
-
84878809061
-
Tanezumab reduces Osteoarthritic hip pain: Results of a randomized, double-blind, placebo-controlled phase III trial
-
Brown MT, Murphy FT, Radin DM, et al. Tanezumab reduces Osteoarthritic hip pain: results of a randomized, double-blind, placebo-controlled phase III trial. Arthritis Rheum 2013;65:1795-803
-
(2013)
Arthritis Rheum
, vol.65
, pp. 1795-1803
-
-
Brown, M.T.1
Murphy, F.T.2
Radin, D.M.3
-
21
-
-
78649756871
-
Administration of a tropomyosin receptor kinase inhibitor attenuates sarcomainduced nerve sprouting, neuroma formation and bone cancer pain
-
Ghilardi JR, Freeman KT, Jimenez-Andrade JM, et al. Administration of a tropomyosin receptor kinase inhibitor attenuates sarcomainduced nerve sprouting, neuroma formation and bone cancer pain. Mol Pain 2010;6:87-100
-
(2010)
Mol Pain
, vol.6
, pp. 87-100
-
-
Ghilardi, J.R.1
Freeman, K.T.2
Jimenez-Andrade, J.M.3
-
24
-
-
84883636957
-
Expression of nerve growth factor and matrix metallopeptidase-9/tissue inhibitor of metalloproteinase-1 in asthmatic patients
-
Kim JS, Kang JY, Ha JH, et al. Expression of nerve growth factor and matrix metallopeptidase-9/tissue inhibitor of metalloproteinase-1 in asthmatic patients. J Asthma 2013;50:712-17
-
(2013)
J Asthma
, vol.50
, pp. 712-717
-
-
Kim, J.S.1
Kang, J.Y.2
Ha, J.H.3
-
25
-
-
84884760247
-
Nerve growth factor exacerbates allergic lung inflammation and airway remodeling in a rat model of chronic asthma
-
Yang YG, Tian WM, Zhang H. Nerve growth factor exacerbates allergic lung inflammation and airway remodeling in a rat model of chronic asthma. Exp Ther Med 2013;6:1251-8
-
(2013)
Exp Ther Med
, vol.6
, pp. 1251-1258
-
-
Yang, Y.G.1
Tian, W.M.2
Zhang, H.3
-
26
-
-
85067772353
-
-
Creabilis Announces Headline Results of its Phase 2b Trial of Topical TrkA Kinase Inhibitor CT327PR Newswire. 2013. Available from [Last Accessed 22 January 2014]
-
Creabilis Announces Headline Results of its Phase 2b Trial of Topical TrkA Kinase Inhibitor CT327. PR Newswire. 2013. Available from: http://www.prnewswire.com/newsreleases/creabilis-announces-headlineresults-of- its-phase-2b-trial-of-topicaltrka-kinase-inhibitor-ct327-206885021. html [Last Accessed 22 January 2014]
-
-
-
-
27
-
-
63149097269
-
Trypanosoma cruzi promotes neuronal and glial cell survival through the neurotrophic receptor TrkC
-
Weinkauf C, Pereiraperrin M. Trypanosoma cruzi promotes neuronal and glial cell survival through the neurotrophic receptor TrkC. Infect Immun 2009;77:1368-75
-
(2009)
Infect Immun
, vol.77
, pp. 1368-1375
-
-
Weinkauf, C.1
Pereiraperrin, M.2
-
28
-
-
80855141156
-
Neurotrophin receptor TrkC is an entry receptor for Trypanosoma cruzi in neural, glial, and epithelial cells
-
Weinkauf C, Salvador R, Pereiraperrin M. Neurotrophin receptor TrkC is an entry receptor for Trypanosoma cruzi in neural, glial, and epithelial cells. Infect Immun 2011;79:4081-7
-
(2011)
Infect Immun
, vol.79
, pp. 4081-4087
-
-
Weinkauf, C.1
Salvador, R.2
Pereiraperrin, M.3
-
29
-
-
84863179654
-
Discovery of GNF-5837, a selective TRK inhibitor with efficacy in rodent cancer tumor models
-
Albaugh P, Fan Y, Mi Y, Sun F. Discovery of GNF-5837, a selective TRK inhibitor with efficacy in rodent cancer tumor models. ACS Med Chem Lett 2012;3:140-5
-
(2012)
ACS Med Chem Lett
, vol.3
, pp. 140-145
-
-
Albaugh, P.1
Fan, Y.2
Mi, Y.3
Sun, F.4
-
30
-
-
18344395134
-
Inhibition of p38 MAP kinase by utilizing a novel allosteric binding site
-
DOI 10.1038/nsb770
-
Pargellis C, Tong L, Churchill L. Inhibition of p38 MAP kinase by utilizing a novel allosteric binding site. Nat Struct Biol 2002;9:268-72 (Pubitemid 34289898)
-
(2002)
Nature Structural Biology
, vol.9
, Issue.4
, pp. 268-272
-
-
Pargellis, C.1
Tong, L.2
Churchill, L.3
Cirillo, P.F.4
Gilmore, T.5
Graham, A.G.6
Grob, P.M.7
Hickey, E.R.8
Moss, N.9
Pav, S.10
Regan, J.11
-
31
-
-
84866382292
-
Discovery of Disubstituted Imidazo[4,5-b]pyridines and purines as potent TrkA inhibitors
-
Wang T, Lamb ML, Block MH, et al. Discovery of Disubstituted Imidazo[4,5-b]pyridines and purines as potent TrkA inhibitors. ACS Med Chem Lett 2012;3:705-9
-
(2012)
ACS Med Chem Lett
, vol.3
, pp. 705-709
-
-
Wang, T.1
Lamb, M.L.2
Block, M.H.3
-
32
-
-
49449105822
-
Identification of 4-Aminopyrazolylpyrimidines as potent inhibitors of Trk kinases
-
Wang T, Lamb ML, Scott DA, et al. Identification of 4- Aminopyrazolylpyrimidines as potent inhibitors of Trk kinases. J Med Chem 2008;51:4672-84
-
(2008)
J Med Chem
, vol.51
, pp. 4672-4684
-
-
Wang, T.1
Lamb, M.L.2
Scott, D.A.3
-
33
-
-
84867034578
-
The crystal structures of TrkA and TrkB suggest key regions for achieving selective inhibition
-
Bertrand T, Kothe M, Liu J. The crystal structures of TrkA and TrkB suggest key regions for achieving selective inhibition. J Mol Biol 2012;423:439-53
-
(2012)
J Mol Biol
, vol.423
, pp. 439-453
-
-
Bertrand, T.1
Kothe, M.2
Liu, J.3
-
34
-
-
67649392442
-
Trk kinase inhibitors as new treatments for cancer and pain
-
Wang T, Yu D, Lamb ML. Trk kinase inhibitors as new treatments for cancer and pain. Expert Opin Ther Pat 2009;19:305-19
-
(2009)
Expert Opin Ther Pat
, vol.19
, pp. 305-319
-
-
Wang, T.1
Yu, D.2
Lamb, M.L.3
-
35
-
-
85067776484
-
-
WO2010033941
-
Andrews SW, Haas J, Jiang Y, Zhang G. Substituted imidazo[1,2-b] pyridazine compounds as Trk kinase inhibitors and their preparation, pharmaceutical compositions and use in the treatment of diseases. WO2010033941; 2010
-
(2010)
Substituted imidazo[1,2-b]pyridazine Compounds As Trk Kinase Inhibitors and Their Preparation, Pharmaceutical Compositions and Use in the Treatment of Diseases
-
-
Andrews, S.W.1
Haas, J.2
Jiang, Y.3
Zhang, G.4
-
44
-
-
33646480747
-
Reversal of Alzheimer's-like pathology and behavior in human APP transgenic mice by mutation of Asp664
-
Galvan V, Gorostiza OF, Banwait S, et al. Reversal of Alzheimer's-like pathology and behavior in human APP transgenic mice by mutation of Asp664. Proc Natl Acad Sci USA 2006;103:7130-5
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 7130-7135
-
-
Galvan, V.1
Gorostiza, O.F.2
Banwait, S.3
-
52
-
-
33845360035
-
Ba/F3 cells and their use in kinase drug discovery
-
DOI 10.1097/CCO.0b013e328011a25f, PII 0000162220070100000011
-
Warmuth M, Kim S, Gu XJ. Ba/F3 cells and their use in kinase drug discovery. Curr Opin Oncol 2007;19:55-60 (Pubitemid 44885601)
-
(2007)
Current Opinion in Oncology
, vol.19
, Issue.1
, pp. 55-60
-
-
Warmuth, M.1
Kim, S.2
Gu, X.-J.3
Xia, G.4
Adrian, F.5
-
54
-
-
80054107932
-
Deuterium in drug discovery and development
-
Harbeson SL, Tung RD. Deuterium in drug discovery and development. Annu Rep Med Chem 2011;46:403-17
-
(2011)
Annu Rep Med Chem
, vol.46
, pp. 403-417
-
-
Harbeson, S.L.1
Tung, R.D.2
-
63
-
-
84864213321
-
The discovery and optimization of a novel class of potent, selective, and orally bioavailable Anaplastic Lymphoma Kinase (ALK) inhibitors with potential utility for the treatment of cancer
-
Lewis RT, Bode CM, Choquette DM, Potashman M. The discovery and optimization of a novel class of potent, selective, and orally bioavailable Anaplastic Lymphoma Kinase (ALK) inhibitors with potential utility for the treatment of cancer. J Med Chem 2012;55:6523-40
-
(2012)
J Med Chem
, vol.55
, pp. 6523-6540
-
-
Lewis, R.T.1
Bode, C.M.2
Choquette, D.M.3
Potashman, M.4
-
65
-
-
84878946619
-
Tofacitinib: A Review of its Use in Adult Patients with Rheumatoid Arthritis
-
Scott LJ. Tofacitinib: a Review of its Use in Adult Patients with Rheumatoid Arthritis. Drugs 2013;73:857-74
-
(2013)
Drugs
, vol.73
, pp. 857-874
-
-
Scott, L.J.1
-
66
-
-
84874993197
-
GSK1120212 in the treatment of melanoma
-
Salama AKS, Kim KB. (GSK1120212) in the treatment of melanoma. Expert Opin Pharmacother 2013;14:619-27
-
(2013)
Expert Opin Pharmacother
, vol.14
, pp. 619-627
-
-
Aks, S.1
Kim, K.B.2
-
67
-
-
84890899629
-
Treatment of BRAF-mutant melanoma: The role of Vemurafenib and other therapies
-
Jang S, Atkins MB. Treatment of BRAF-mutant melanoma: the role of Vemurafenib and other therapies. Clin Pharmacol Ther 2014;95:24-31
-
(2014)
Clin Pharmacol Ther
, vol.95
, pp. 24-31
-
-
Jang, S.1
Atkins, M.B.2
-
68
-
-
84879999533
-
Dabrafenib in the treatment of advanced melanoma
-
Medina T, Amaria M.N, Jimeno A. Dabrafenib in the treatment of advanced melanoma. Drugs Today (Barc) 2013;49:377-85
-
(2013)
Drugs Today (Barc
, vol.49
, pp. 377-385
-
-
Medina, T.1
Amaria, M.N.2
Jimeno, A.3
-
69
-
-
84877839495
-
Ponatinib for the treatment of chronic myeloid leukemia and Philadelphia chromosome-positive acute lymphoblastic leukemia
-
Narayanan V, Pollyea DA, Gutman JA, Jimeno A. Ponatinib for the treatment of chronic myeloid leukemia and Philadelphia chromosome-positive acute lymphoblastic leukemia. Drugs Today (Barc) 2013;49:261-9
-
(2013)
Drugs Today (Barc
, vol.49
, pp. 261-269
-
-
Narayanan, V.1
Pollyea, D.A.2
Gutman, J.A.3
Jimeno, A.4
-
70
-
-
44849093414
-
A preclinical review of sunitinib, a multitargeted receptor tyrosine kinase inhibitor with anti-angiogenic and antitumour activities
-
Christensen JG. A preclinical review of sunitinib, a multitargeted receptor tyrosine kinase inhibitor with anti-angiogenic and antitumour activities. Ann Oncol 2007;18:3-10
-
(2007)
Ann Oncol
, vol.18
, pp. 3-10
-
-
Christensen, J.G.1
-
71
-
-
84872892692
-
Efficacy and safety of regorafenib for advanced gastrointestinal stromal tumours after failure of imatinib and sunitinib (GRID): An international, multicentre, randomised, placebocontrolled, phase 3 trial
-
Demetri GD, Reicchardt P, Kang YK, Blay JY. Efficacy and safety of regorafenib for advanced gastrointestinal stromal tumours after failure of imatinib and sunitinib (GRID): an international, multicentre, randomised, placebocontrolled, phase 3 trial. Lancet 2013;381:295-302
-
(2013)
Lancet
, vol.381
, pp. 295-302
-
-
Demetri, G.D.1
Reicchardt, P.2
Kang, Y.K.3
Blay, J.Y.4
-
72
-
-
77649204688
-
Selectively nonselective kinase inhibition: Striking the right balance
-
Morphy R. Selectively nonselective kinase inhibition: striking the right balance. J Med Chem 2010;53:1413-37
-
(2010)
J Med Chem
, vol.53
, pp. 1413-1437
-
-
Morphy, R.1
-
73
-
-
1842420032
-
Single-agent CEP-701, a novel FLT3 inhibitor, shows biologic and clinical activity in patients with relapsed or refractory acute myeloid leukemia
-
DOI 10.1182/blood-2003-11-3775
-
Smith BD, Levis M, Beran M, et al. Single-agent CEP-701, a novel FLT3 inhibitor, shows biologic and clinical activity in patients with relapsed or refractory acute myeloid leukemia. Blood 2004;103:3669-76 (Pubitemid 38596280)
-
(2004)
Blood
, vol.103
, Issue.10
, pp. 3669-3676
-
-
Smith, B.D.1
Levis, M.2
Beran, M.3
Giles, F.4
Kantarjian, H.5
Berg, K.6
Murphy, K.M.7
Dauses, T.8
Allebach, J.9
Small, D.10
-
74
-
-
77949535491
-
Phase 2 study of CEP-701, an orally available JAK2 inhibitor, in patients with primary or postpolycythemia vera/essential thrombocythemia myelofibrosis
-
Santos FPS, Kantarjian HM, Jain N, et al. Phase 2 study of CEP-701, an orally available JAK2 inhibitor, in patients with primary or postpolycythemia vera/essential thrombocythemia myelofibrosis. Blood 2010;115:1131-6
-
(2010)
Blood
, vol.115
, pp. 1131-1136
-
-
Fps, S.1
Kantarjian, H.M.2
Jain, N.3
-
75
-
-
76949083372
-
Lestaurtinib, a multitargeted tyrosine kinase inhibitor: From bench to bedside
-
Shabbir M SR. Lestaurtinib, a multitargeted tyrosine kinase inhibitor: from bench to bedside. Expert Opin Investig Drugs 2010;19:427-36
-
(2010)
Expert Opin Investig Drugs
, vol.19
, pp. 427-436
-
-
Shabbir, M.S.R.1
-
76
-
-
70249098518
-
Clinical experience with Aurora kinase inhibitors: A review
-
Boss DS, Beijnen JH, Schellens JHM. Clinical experience with Aurora kinase inhibitors: a review. Oncologist 2009;14:780-93
-
(2009)
Oncologist
, vol.14
, pp. 780-793
-
-
Boss, D.S.1
Beijnen, J.H.2
Jhm, S.3
-
77
-
-
84879602359
-
Foretinib (XL880): C-MET inhibitor with activity in papillary renal cell cancer
-
Logan TF. Foretinib (XL880): c-MET inhibitor with activity in papillary renal cell cancer. Curr Oncol Rep 2013;15:83-90
-
(2013)
Curr Oncol Rep
, vol.15
, pp. 83-90
-
-
Logan, T.F.1
-
78
-
-
85067781185
-
-
Phase I Open-label Dose-escalation Safety and PK Study of AZD6918i NIH clinical trial notification. 2010. Available from [Last accessed 21 January 2014]
-
Phase I, Open-label, Dose-escalation, Safety and PK Study of AZD6918. NIH clinical trial notification. 2010. Available from: http://clinicaltrials. gov/show/NCT00733031 [Last accessed 21 January 2014]
-
-
-
-
79
-
-
0041488911
-
Trk receptors: Roles in neuronal signal transduction
-
DOI 10.1146/annurev.biochem.72.121801.161629
-
Huang EJ, Reichardt LF. Trk receptors: roles in neuronal signal transduction. Annu Rev Biochem 2003;72:609-42 (Pubitemid 36930455)
-
(2003)
Annual Review of Biochemistry
, vol.72
, pp. 609-642
-
-
Huang, E.J.1
Reichardt, L.F.2
-
80
-
-
84855503769
-
The rise and fall of gatekeeper mutations? the BCR-ABL1 T315I paradigm
-
Gibbons DL, Pricl S, Kantarjian H, Cortes J. The rise and fall of gatekeeper mutations? The BCR-ABL1 T315I paradigm. Cancer 2012;118:293-9
-
(2012)
Cancer
, vol.118
, pp. 293-299
-
-
Gibbons, D.L.1
Pricl, S.2
Kantarjian, H.3
Cortes, J.4
-
81
-
-
64349099558
-
Kinase domain mutations in cancer: Implications for small molecule drug design strategies
-
Bikker JA, Brooijmans N, Wissner A, Mansour TS. Kinase domain mutations in cancer: implications for small molecule drug design strategies. J Med Chem 2009;52:1493-509
-
(2009)
J Med Chem
, vol.52
, pp. 1493-1509
-
-
Bikker, J.A.1
Brooijmans, N.2
Wissner, A.3
Mansour, T.S.4
|