메뉴 건너뛰기




Volumn 15, Issue 2, 2013, Pages 83-90

Foretinib (XL880): C-MET inhibitor with activity in papillary renal cell cancer

Author keywords

Foretinib; MET; Papillary renal cell cancer

Indexed keywords

CABOZANTINIB; ERLOTINIB; FORETINIB; FUMARATE HYDRATASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; RAC1 PROTEIN; RAP1 PROTEIN; SCATTER FACTOR RECEPTOR; SUNITINIB; UNCLASSIFIED DRUG; VASCULOTROPIN INHIBITOR; VASCULOTROPIN RECEPTOR 2; WNT PROTEIN; XL 999;

EID: 84879602359     PISSN: 15233790     EISSN: 15346269     Source Type: Journal    
DOI: 10.1007/s11912-013-0299-3     Document Type: Article
Times cited : (26)

References (106)
  • 2
    • 0022912449 scopus 로고
    • Histopathology and classification of renal cell tumors (adenomas, oncocytomas and carcinomas). The basic cytological and histopathological elements and their use for diagnostics
    • 3737468 1:STN:280:DyaL283os12ntg%3D%3D 10.1016/S0344-0338(86)80001-2
    • Thoenes W, Storkel S, Rumpelt HJ. Histopathology and classification of renal cell tumors (adenomas, oncocytomas and carcinomas). The basic cytological and histopathological elements and their use for diagnostics. Pathol Res Pract. 1986;181:125-43.
    • (1986) Pathol Res Pract , vol.181 , pp. 125-143
    • Thoenes, W.1    Storkel, S.2    Rumpelt, H.J.3
  • 3
    • 0017076579 scopus 로고
    • Clinical comparison between vascular and avascular renal cell carcinoma
    • 1271541 1:STN:280:DyaE287psVSgsA%3D%3D
    • Blath RA, Mancilla-Jimenez R, Stanley RJ. Clinical comparison between vascular and avascular renal cell carcinoma. J Urol. 1976;115:514-9.
    • (1976) J Urol , vol.115 , pp. 514-519
    • Blath, R.A.1    Mancilla-Jimenez, R.2    Stanley, R.J.3
  • 4
    • 0017030135 scopus 로고
    • Papillary renal cell carcinoma: A clinical, radiologic, and pathologic study of 34 cases
    • 1000477 1:STN:280:DyaE2s%2Fms1OmsQ%3D%3D 10.1002/1097-0142(197612)38: 6<2469: AID-CNCR2820380636>3.0.CO;2-R
    • Mancilla-Jimenez R, Stanley RJ, Blath RA. Papillary renal cell carcinoma: a clinical, radiologic, and pathologic study of 34 cases. Cancer. 1976;38:2469-80.
    • (1976) Cancer , vol.38 , pp. 2469-2480
    • Mancilla-Jimenez, R.1    Stanley, R.J.2    Blath, R.A.3
  • 5
    • 0024512575 scopus 로고
    • Differentiation between papillary and nonpapillary renal cell carcinomas by DNA analysis
    • 2921777 1:STN:280:DyaL1M7lslGntQ%3D%3D 10.1093/jnci/81.7.527
    • Kovacs G, Wilkens L, Papp T, de Riese W. Differentiation between papillary and nonpapillary renal cell carcinomas by DNA analysis. J Natl Cancer Inst. 1989;81:527-30.
    • (1989) J Natl Cancer Inst , vol.81 , pp. 527-530
    • Kovacs, G.1    Wilkens, L.2    Papp, T.3    De Riese, W.4
  • 6
    • 0024495675 scopus 로고
    • Papillary renal cell carcinoma. A morphologic and cytogenetic study of 11 cases
    • 2913826 1:STN:280:DyaL1M7hs1entg%3D%3D
    • Kovacs G. Papillary renal cell carcinoma. A morphologic and cytogenetic study of 11 cases. Am J Pathol. 1989;134:27-34.
    • (1989) Am J Pathol , vol.134 , pp. 27-34
    • Kovacs, G.1
  • 7
    • 0025948432 scopus 로고
    • Cytogenetics of papillary renal cell tumors
    • 1958590 1:STN:280:DyaK38%2FmvV2isQ%3D%3D 10.1002/gcc.2870030403
    • Kovacs G, Fuzesi L, Emanual A, Kung HF. Cytogenetics of papillary renal cell tumors. Genes Chromosom Cancer. 1991;3:249-55.
    • (1991) Genes Chromosom Cancer , vol.3 , pp. 249-255
    • Kovacs, G.1    Fuzesi, L.2    Emanual, A.3    Kung, H.F.4
  • 8
    • 0029148373 scopus 로고
    • Papillary renal tumors. Morphologic, cytochemical, and genotypic features
    • 8625163 1:STN:280:DyaK283itlSrtA%3D%3D 10.1002/1097-0142(19950815)76: 4<669: AID-CNCR2820760420>3.0.CO;2-U
    • Lager DJ, Huston BJ, Timmerman TG, Bonsib SM. Papillary renal tumors. Morphologic, cytochemical, and genotypic features. Cancer. 1995;76:669-73.
    • (1995) Cancer , vol.76 , pp. 669-673
    • Lager, D.J.1    Huston, B.J.2    Timmerman, T.G.3    Bonsib, S.M.4
  • 9
    • 0027442691 scopus 로고
    • Molecular cytogenetics of renal cell tumors
    • 8109322 1:CAS:528:DyaK2cXksl2mu7s%3D 10.1016/S0065-230X(08)60316-4
    • Kovacs G. Molecular cytogenetics of renal cell tumors. Adv Cancer Res. 1993;62:89-124.
    • (1993) Adv Cancer Res , vol.62 , pp. 89-124
    • Kovacs, G.1
  • 10
    • 70349678985 scopus 로고    scopus 로고
    • Trisomy 7 and 17 mark papillary renal cell tumours irrespectively of variation of the phenotype
    • 19541684 1:STN:280:DC%2BD1MnkvVantQ%3D%3D 10.1136/jcp.2009.066423
    • Balint I, Szponar A, Jauch A, Kovacs G. Trisomy 7 and 17 mark papillary renal cell tumours irrespectively of variation of the phenotype. J Clin Pathol. 2009;62:892-5.
    • (2009) J Clin Pathol , vol.62 , pp. 892-895
    • Balint, I.1    Szponar, A.2    Jauch, A.3    Kovacs, G.4
  • 11
    • 0031255567 scopus 로고    scopus 로고
    • The Heidelberg classification of renal cell tumours
    • 9390023 1:CAS:528:DyaK2sXntVSltb0%3D 10.1002/(SICI)1096-9896(199710)183: 2<131: AID-PATH931>3.0.CO;2-G
    • Kovacs G, Akhtar M, Beckwith BJ, et al. The Heidelberg classification of renal cell tumours. J Pathol. 1997;183:131-3.
    • (1997) J Pathol , vol.183 , pp. 131-133
    • Kovacs, G.1    Akhtar, M.2    Beckwith, B.J.3
  • 12
    • 0037378739 scopus 로고    scopus 로고
    • Review of papillary renal cell carcinoma with focus on clinical and pathobiological aspects
    • 12647800 1:STN:280:DC%2BD3s7jtlalsw%3D%3D
    • Kuroda N, Toi M, Hiroi M, Enzan H. Review of papillary renal cell carcinoma with focus on clinical and pathobiological aspects. Histol Histopathol. 2003;18:487-94.
    • (2003) Histol Histopathol , vol.18 , pp. 487-494
    • Kuroda, N.1    Toi, M.2    Hiroi, M.3    Enzan, H.4
  • 13
    • 2142853538 scopus 로고    scopus 로고
    • Effect of papillary and chromophobe cell type on disease-free survival after nephrectomy for renal cell carcinoma
    • 14699037 10.1007/BF02524349
    • Beck SD, Patel MI, Snyder ME, et al. Effect of papillary and chromophobe cell type on disease-free survival after nephrectomy for renal cell carcinoma. Ann Surg Oncol. 2004;11:71-7.
    • (2004) Ann Surg Oncol , vol.11 , pp. 71-77
    • Beck, S.D.1    Patel, M.I.2    Snyder, M.E.3
  • 14
    • 0030904772 scopus 로고    scopus 로고
    • Papillary (chromophil) renal cell carcinoma: Histomorphologic characteristics and evaluation of conventional pathologic prognostic parameters in 62 cases
    • 9199639 1:STN:280:DyaK2szktlSisg%3D%3D 10.1097/00000478-199706000-00001
    • Amin MB, Corless CL, Renshaw AA, Tickoo SK, Kubus J, Schultz DS. Papillary (chromophil) renal cell carcinoma: histomorphologic characteristics and evaluation of conventional pathologic prognostic parameters in 62 cases. Am J Surg Pathol. 1997;21:621-35.
    • (1997) Am J Surg Pathol , vol.21 , pp. 621-635
    • Amin, M.B.1    Corless, C.L.2    Renshaw, A.A.3    Tickoo, S.K.4    Kubus, J.5    Schultz, D.S.6
  • 15
    • 0020376310 scopus 로고
    • Prognostic significance of morphologic parameters in renal cell carcinoma
    • 7180965 1:STN:280:DyaL3s%2FpvVWhtg%3D%3D 10.1097/00000478-198210000-00007
    • Fuhrman SA, Lasky LC, Limas C. Prognostic significance of morphologic parameters in renal cell carcinoma. Am J Surg Pathol. 1982;6:655-63.
    • (1982) Am J Surg Pathol , vol.6 , pp. 655-663
    • Fuhrman, S.A.1    Lasky, L.C.2    Limas, C.3
  • 16
    • 0037407573 scopus 로고    scopus 로고
    • Comparisons of outcome and prognostic features among histologic subtypes of renal cell carcinoma
    • 12717246 10.1097/00000478-200305000-00005
    • Cheville JC, Lohse CM, Zincke H, Weaver AL, Blute ML. Comparisons of outcome and prognostic features among histologic subtypes of renal cell carcinoma. Am J Surg Pathol. 2003;27:612-24.
    • (2003) Am J Surg Pathol , vol.27 , pp. 612-624
    • Cheville, J.C.1    Lohse, C.M.2    Zincke, H.3    Weaver, A.L.4    Blute, M.L.5
  • 17
    • 0036131438 scopus 로고    scopus 로고
    • Prognostic features of pathologic stage T1 renal cell carcinoma after radical nephrectomy
    • 11927308 10.1016/S0090-4295(01)01589-8
    • Lau WK, Cheville JC, Blute ML, Weaver AL, Zincke H. Prognostic features of pathologic stage T1 renal cell carcinoma after radical nephrectomy. Urology. 2002;59:532-7.
    • (2002) Urology , vol.59 , pp. 532-537
    • Lau, W.K.1    Cheville, J.C.2    Blute, M.L.3    Weaver, A.L.4    Zincke, H.5
  • 18
    • 0032727583 scopus 로고    scopus 로고
    • Prognostic significance of the Heidelberg classification of renal cell carcinoma
    • 10559609 1:STN:280:DC%2BD3c%2Fis1SmsQ%3D%3D 10.1159/000020049
    • Ljungberg B, Alamdari FI, Stenling R, Roos G. Prognostic significance of the Heidelberg classification of renal cell carcinoma. Eur Urol. 1999;36:565-9.
    • (1999) Eur Urol , vol.36 , pp. 565-569
    • Ljungberg, B.1    Alamdari, F.I.2    Stenling, R.3    Roos, G.4
  • 19
    • 0034255304 scopus 로고    scopus 로고
    • Prognostic utility of the recently recommended histologic classification and revised TNM staging system of renal cell carcinoma: A Swiss experience with 588 tumors
    • 10931460 1:STN:280:DC%2BD3cvgt1artA%3D%3D 10.1002/1097-0142(20000801)89: 3<604: AID-CNCR16>3.0.CO;2-Q
    • Moch H, Gasser T, Amin MB, Torhorst J, Sauter G, Mihatsch MJ. Prognostic utility of the recently recommended histologic classification and revised TNM staging system of renal cell carcinoma: a Swiss experience with 588 tumors. Cancer. 2000;89:604-14.
    • (2000) Cancer , vol.89 , pp. 604-614
    • Moch, H.1    Gasser, T.2    Amin, M.B.3    Torhorst, J.4    Sauter, G.5    Mihatsch, M.J.6
  • 20
    • 0033050059 scopus 로고    scopus 로고
    • Papillary renal cell carcinoma: Clinicopathological characteristics and evaluation of prognosis in 42 patients
    • 10368232 1:STN:280:DyaK1M3ps1Orsw%3D%3D 10.1046/j.1464-410x.1999.00094.x
    • Onishi T, Ohishi Y, Goto H, Suzuki M, Miyazawa Y. Papillary renal cell carcinoma: clinicopathological characteristics and evaluation of prognosis in 42 patients. BJU Int. 1999;83:937-43.
    • (1999) BJU Int , vol.83 , pp. 937-943
    • Onishi, T.1    Ohishi, Y.2    Goto, H.3    Suzuki, M.4    Miyazawa, Y.5
  • 21
    • 54949093221 scopus 로고    scopus 로고
    • Comparison of type i and II papillary renal cell carcinoma (RCC) and clear cell RCC
    • 18782311
    • Waldert M, Haitel A, Marberger M, et al. Comparison of type I and II papillary renal cell carcinoma (RCC) and clear cell RCC. BJU Int. 2008;102:1381-4.
    • (2008) BJU Int , vol.102 , pp. 1381-1384
    • Waldert, M.1    Haitel, A.2    Marberger, M.3
  • 22
    • 21044433148 scopus 로고    scopus 로고
    • Prognostic value of histologic subtypes in renal cell carcinoma: A multicenter experience
    • 15837991 10.1200/JCO.2005.07.055
    • Patard JJ, Leray E, Rioux-Leclercq N, et al. Prognostic value of histologic subtypes in renal cell carcinoma: a multicenter experience. J Clin Oncol. 2005;23:2763-71.
    • (2005) J Clin Oncol , vol.23 , pp. 2763-2771
    • Patard, J.J.1    Leray, E.2    Rioux-Leclercq, N.3
  • 23
    • 41149090291 scopus 로고    scopus 로고
    • Analysis of clinicopathologic predictors of oncologic outcome provides insight into the natural history of surgically managed papillary renal cell carcinoma
    • 18240184 10.1002/cncr.23322
    • Margulis V, Tamboli P, Matin SF, Swanson DA, Wood CG. Analysis of clinicopathologic predictors of oncologic outcome provides insight into the natural history of surgically managed papillary renal cell carcinoma. Cancer. 2008;112:1480-8.
    • (2008) Cancer , vol.112 , pp. 1480-1488
    • Margulis, V.1    Tamboli, P.2    Matin, S.F.3    Swanson, D.A.4    Wood, C.G.5
  • 24
    • 33748307360 scopus 로고    scopus 로고
    • Prognostic role of the histologic subtypes of renal cell carcinoma after slide revision
    • 16697521 10.1016/j.eururo.2006.04.009
    • Ficarra V, Martignoni G, Galfano A, et al. Prognostic role of the histologic subtypes of renal cell carcinoma after slide revision. Eur Urol. 2006;50:786-93.
    • (2006) Eur Urol , vol.50 , pp. 786-793
    • Ficarra, V.1    Martignoni, G.2    Galfano, A.3
  • 25
    • 24644496731 scopus 로고    scopus 로고
    • Histological subtyping and nuclear grading of renal cell carcinoma and their implications for survival: A retrospective nation-wide study of 629 patients
    • 15964127 10.1016/j.eururo.2005.04.016
    • Gudbjartsson T, Hardarson S, Petursdottir V, Thoroddsen A, Magnusson J, Einarsson GV. Histological subtyping and nuclear grading of renal cell carcinoma and their implications for survival: a retrospective nation-wide study of 629 patients. Eur Urol. 2005;48:593-600.
    • (2005) Eur Urol , vol.48 , pp. 593-600
    • Gudbjartsson, T.1    Hardarson, S.2    Petursdottir, V.3    Thoroddsen, A.4    Magnusson, J.5    Einarsson, G.V.6
  • 26
    • 34248149330 scopus 로고    scopus 로고
    • Multi-institutional validation of a new renal cancer-specific survival nomogram
    • 17416852 10.1200/JCO.2006.06.1218
    • Karakiewicz PI, Briganti A, Chun FK, et al. Multi-institutional validation of a new renal cancer-specific survival nomogram. J Clin Oncol. 2007;25:1316-22.
    • (2007) J Clin Oncol , vol.25 , pp. 1316-1322
    • Karakiewicz, P.I.1    Briganti, A.2    Chun, F.K.3
  • 27
    • 84863722464 scopus 로고    scopus 로고
    • Histopathology of surgically treated renal cell carcinoma: Survival differences by subtype and stage
    • 22698625 10.1016/j.juro.2012.04.006
    • Keegan KA, Schupp CW, Chamie K, Hellenthal NJ, Evans CP, Koppie TM. Histopathology of surgically treated renal cell carcinoma: survival differences by subtype and stage. J Urol. 2012;188:391-7.
    • (2012) J Urol , vol.188 , pp. 391-397
    • Keegan, K.A.1    Schupp, C.W.2    Chamie, K.3    Hellenthal, N.J.4    Evans, C.P.5    Koppie, T.M.6
  • 28
    • 65549116904 scopus 로고    scopus 로고
    • A critical assessment of the prognostic value of clear cell, papillary and chromophobe histological subtypes in renal cell carcinoma: A population-based study
    • 19076149 10.1111/j.1464-410X.2008.08259.x
    • Capitanio U, Cloutier V, Zini L, et al. A critical assessment of the prognostic value of clear cell, papillary and chromophobe histological subtypes in renal cell carcinoma: a population-based study. BJU Int. 2009;103:1496-500.
    • (2009) BJU Int , vol.103 , pp. 1496-1500
    • Capitanio, U.1    Cloutier, V.2    Zini, L.3
  • 29
    • 77949280134 scopus 로고    scopus 로고
    • Histological subtype is an independent predictor of outcome for patients with renal cell carcinoma
    • 20171681 10.1016/j.juro.2009.12.035 This is a recent large single-institution study showing a positive prognotic effect of papillary RCC compared with clear cell RCC histologic subtype by multivariate analysis
    • • Leibovich BC, Lohse CM, Crispen PL, et al. Histological subtype is an independent predictor of outcome for patients with renal cell carcinoma. J Urol. 2010;183:1309-15. This is a recent large single-institution study showing a positive prognotic effect of papillary RCC compared with clear cell RCC histologic subtype by multivariate analysis.
    • (2010) J Urol , vol.183 , pp. 1309-1315
    • Leibovich, B.C.1    Lohse, C.M.2    Crispen, P.L.3
  • 30
    • 84866733351 scopus 로고    scopus 로고
    • Incidence and long-term prognosis of papillary compared to clear cell renal cell carcinoma - A multicentre study
    • 22698386 10.1016/j.ejca.2012.05.002 This is a recent large multicenter study comparing papillary RCC and clear cell RCC subtypes. The papillary subtype was found to have a significant positive effect in localized disease but a negative effect in metastatic disease by multivariate analysis. Both [29] and [30] are studies in large numbers of patients and used either a single pathologist or a dedicated group of genitourinary pathologists for slide review. Most of the other cited studies were smaller and did not have dedicated pathology review
    • • Steffens S, Janssen M, Roos FC, et al. Incidence and long-term prognosis of papillary compared to clear cell renal cell carcinoma - a multicentre study. Eur J Cancer. 2012;48:2347-52. This is a recent large multicenter study comparing papillary RCC and clear cell RCC subtypes. The papillary subtype was found to have a significant positive effect in localized disease but a negative effect in metastatic disease by multivariate analysis. Both [29] and [30] are studies in large numbers of patients and used either a single pathologist or a dedicated group of genitourinary pathologists for slide review. Most of the other cited studies were smaller and did not have dedicated pathology review.
    • (2012) Eur J Cancer , vol.48 , pp. 2347-2352
    • Steffens, S.1    Janssen, M.2    Roos, F.C.3
  • 31
    • 0030788677 scopus 로고    scopus 로고
    • Papillary renal cell carcinoma: A clinicopathologic and immunohistochemical study of 105 tumors
    • 9195569 1:STN:280:DyaK2szjvFSjuw%3D%3D
    • Delahunt B, Eble JN. Papillary renal cell carcinoma: a clinicopathologic and immunohistochemical study of 105 tumors. Mod Pathol. 1997;10:537-44.
    • (1997) Mod Pathol , vol.10 , pp. 537-544
    • Delahunt, B.1    Eble, J.N.2
  • 32
    • 0034949144 scopus 로고    scopus 로고
    • Morphologic typing of papillary renal cell carcinoma: Comparison of growth kinetics and patient survival in 66 cases
    • 11431713 1:STN:280:DC%2BD3MzoslyltQ%3D%3D 10.1053/hupa.2001.24984
    • Delahunt B, Eble JN, McCredie MR, Bethwaite PB, Stewart JH, Bilous AM. Morphologic typing of papillary renal cell carcinoma: comparison of growth kinetics and patient survival in 66 cases. Hum Pathol. 2001;32:590-5.
    • (2001) Hum Pathol , vol.32 , pp. 590-595
    • Delahunt, B.1    Eble, J.N.2    McCredie, M.R.3    Bethwaite, P.B.4    Stewart, J.H.5    Bilous, A.M.6
  • 33
    • 63149193393 scopus 로고    scopus 로고
    • Cytogenetic and molecular tumor profiling for type 1 and type 2 papillary renal cell carcinoma
    • 19228721 1:CAS:528:DC%2BD1MXitVOksb8%3D 10.1158/1078-0432.CCR-08-1229
    • Klatte T, Pantuck AJ, Said JW, et al. Cytogenetic and molecular tumor profiling for type 1 and type 2 papillary renal cell carcinoma. Clin Cancer Res. 2009;15:1162-9.
    • (2009) Clin Cancer Res , vol.15 , pp. 1162-1169
    • Klatte, T.1    Pantuck, A.J.2    Said, J.W.3
  • 34
    • 0038364112 scopus 로고    scopus 로고
    • Papillary renal cell carcinoma. Prognostic value of morphological subtypes in a clinicopathologic study of 43 cases
    • 12684768
    • Allory Y, Ouazana D, Boucher E, Thiounn N, Vieillefond A. Papillary renal cell carcinoma. Prognostic value of morphological subtypes in a clinicopathologic study of 43 cases. Virchows Arch. 2003;442:336-42.
    • (2003) Virchows Arch , vol.442 , pp. 336-342
    • Allory, Y.1    Ouazana, D.2    Boucher, E.3    Thiounn, N.4    Vieillefond, A.5
  • 35
    • 77952753366 scopus 로고    scopus 로고
    • Cytogenetic features, clinical significance and prognostic impact of type 1 and type 2 papillary renal cell carcinoma
    • 20471516 1:CAS:528:DC%2BC3cXmtFajsL8%3D 10.1016/j.cancergencyto.2010.02. 013
    • Antonelli A, Tardanico R, Balzarini P, et al. Cytogenetic features, clinical significance and prognostic impact of type 1 and type 2 papillary renal cell carcinoma. Cancer Genet Cytogenet. 2010;199:128-33.
    • (2010) Cancer Genet Cytogenet , vol.199 , pp. 128-133
    • Antonelli, A.1    Tardanico, R.2    Balzarini, P.3
  • 36
    • 17444437580 scopus 로고    scopus 로고
    • Prognostic factors for the survival of patients with papillary renal cell carcinoma: Meaning of histological typing and multifocality
    • 12913693 10.1097/01.ju.0000081122.57148.ec
    • Mejean A, Hopirtean V, Bazin JP, et al. Prognostic factors for the survival of patients with papillary renal cell carcinoma: meaning of histological typing and multifocality. J Urol. 2003;170:764-7.
    • (2003) J Urol , vol.170 , pp. 764-767
    • Mejean, A.1    Hopirtean, V.2    Bazin, J.P.3
  • 37
    • 33847028817 scopus 로고    scopus 로고
    • Survival analysis of 130 patients with papillary renal cell carcinoma: Prognostic utility of type 1 and type 2 subclassification
    • 17275070 10.1016/j.urology.2006.09.052
    • Pignot G, Elie C, Conquy S, et al. Survival analysis of 130 patients with papillary renal cell carcinoma: prognostic utility of type 1 and type 2 subclassification. Urology. 2007;69:230-5.
    • (2007) Urology , vol.69 , pp. 230-235
    • Pignot, G.1    Elie, C.2    Conquy, S.3
  • 38
    • 50049106969 scopus 로고    scopus 로고
    • Prognostic factors in a prospective series of papillary renal cell carcinoma
    • 18489525 10.1111/j.1464-410X.2008.07756.x
    • Gontero P, Ceratti G, Guglielmetti S, et al. Prognostic factors in a prospective series of papillary renal cell carcinoma. BJU Int. 2008;102:697-702.
    • (2008) BJU Int , vol.102 , pp. 697-702
    • Gontero, P.1    Ceratti, G.2    Guglielmetti, S.3
  • 39
    • 70349971911 scopus 로고    scopus 로고
    • Is there a role of the histologic subtypes of papillary renal cell carcinoma as a prognostic factor?
    • 19586962 10.1093/jjco/hyp075
    • Ku JH, Moon KC, Kwak C, Kim HH, Lee SE. Is there a role of the histologic subtypes of papillary renal cell carcinoma as a prognostic factor? Jpn J Clin Oncol. 2009;39:664-70.
    • (2009) Jpn J Clin Oncol , vol.39 , pp. 664-670
    • Ku, J.H.1    Moon, K.C.2    Kwak, C.3    Kim, H.H.4    Lee, S.E.5
  • 40
    • 77953120400 scopus 로고    scopus 로고
    • Development and external validation of a nomogram predicting disease specific survival after nephrectomy for papillary renal cell carcinoma
    • 20478577 10.1016/j.juro.2010.03.026
    • Klatte T, Remzi M, Zigeuner RE, et al. Development and external validation of a nomogram predicting disease specific survival after nephrectomy for papillary renal cell carcinoma. J Urol. 2010;184:53-8.
    • (2010) J Urol , vol.184 , pp. 53-58
    • Klatte, T.1    Remzi, M.2    Zigeuner, R.E.3
  • 41
    • 83555168193 scopus 로고    scopus 로고
    • Clinical and pathological features associated with prognosis in patients with papillary renal cell carcinoma
    • 22088335 10.1016/j.juro.2011.09.053
    • Sukov WR, Lohse CM, Leibovich BC, Thompson RH, Cheville JC. Clinical and pathological features associated with prognosis in patients with papillary renal cell carcinoma. J Urol. 2012;187:54-9.
    • (2012) J Urol , vol.187 , pp. 54-59
    • Sukov, W.R.1    Lohse, C.M.2    Leibovich, B.C.3    Thompson, R.H.4    Cheville, J.C.5
  • 42
    • 0028897350 scopus 로고
    • Hereditary papillary renal cell carcinoma: Clinical studies in 10 families
    • 7853572 1:STN:280:DyaK2M7ls1Kksg%3D%3D 10.1016/S0022-5347(01)67601-8
    • Zbar B, Glenn G, Lubensky I, et al. Hereditary papillary renal cell carcinoma: clinical studies in 10 families. J Urol. 1995;153:907-12.
    • (1995) J Urol , vol.153 , pp. 907-912
    • Zbar, B.1    Glenn, G.2    Lubensky, I.3
  • 43
    • 0028157342 scopus 로고
    • Hereditary papillary renal cell carcinoma
    • 8308957 1:STN:280:DyaK2c7ktF2qtQ%3D%3D
    • Zbar B, Tory K, Merino M, et al. Hereditary papillary renal cell carcinoma. J Urol. 1994;151:561-6.
    • (1994) J Urol , vol.151 , pp. 561-566
    • Zbar, B.1    Tory, K.2    Merino, M.3
  • 44
    • 0030478646 scopus 로고    scopus 로고
    • Chromosome imbalances in papillary renal cell carcinoma and first cytogenetic data of familial cases analyzed by comparative genomic hybridization
    • 8995481 1:CAS:528:DyaK2sXmtVGgsg%3D%3D 10.1159/000134448
    • Bentz M, Bergerheim US, Li C, et al. Chromosome imbalances in papillary renal cell carcinoma and first cytogenetic data of familial cases analyzed by comparative genomic hybridization. Cytogenet Cell Genet. 1996;75:17-21.
    • (1996) Cytogenet Cell Genet , vol.75 , pp. 17-21
    • Bentz, M.1    Bergerheim, U.S.2    Li, C.3
  • 45
    • 17344381429 scopus 로고    scopus 로고
    • Germline and somatic mutations in the tyrosine kinase domain of the MET proto-oncogene in papillary renal carcinomas
    • 9140397 1:CAS:528:DyaK2sXivFKhsbw%3D 10.1038/ng0597-68
    • Schmidt L, Duh FM, Chen F, et al. Germline and somatic mutations in the tyrosine kinase domain of the MET proto-oncogene in papillary renal carcinomas. Nat Genet. 1997;16:68-73.
    • (1997) Nat Genet , vol.16 , pp. 68-73
    • Schmidt, L.1    Duh, F.M.2    Chen, F.3
  • 46
    • 0032522486 scopus 로고    scopus 로고
    • Two North American families with hereditary papillary renal carcinoma and identical novel mutations in the MET proto-oncogene
    • 9563489 1:CAS:528:DyaK1cXislerurg%3D
    • Schmidt L, Junker K, Weirich G, et al. Two North American families with hereditary papillary renal carcinoma and identical novel mutations in the MET proto-oncogene. Cancer Res. 1998;58:1719-22.
    • (1998) Cancer Res , vol.58 , pp. 1719-1722
    • Schmidt, L.1    Junker, K.2    Weirich, G.3
  • 47
    • 0032514365 scopus 로고    scopus 로고
    • Duplication and overexpression of the mutant allele of the MET proto-oncogene in multiple hereditary papillary renal cell tumours
    • 9715275 1:CAS:528:DyaK1cXls1Smsb8%3D 10.1038/sj.onc.1201983
    • Fischer J, Palmedo G, von Knobloch R, et al. Duplication and overexpression of the mutant allele of the MET proto-oncogene in multiple hereditary papillary renal cell tumours. Oncogene. 1998;17:733-9.
    • (1998) Oncogene , vol.17 , pp. 733-739
    • Fischer, J.1    Palmedo, G.2    Von Knobloch, R.3
  • 48
    • 17344373892 scopus 로고    scopus 로고
    • Trisomy 7-harbouring non-random duplication of the mutant MET allele in hereditary papillary renal carcinomas
    • 9731534 1:CAS:528:DyaK1cXmtVOmtbw%3D 10.1038/1727
    • Zhuang Z, Park WS, Pack S, et al. Trisomy 7-harbouring non-random duplication of the mutant MET allele in hereditary papillary renal carcinomas. Nat Genet. 1998;20:66-9.
    • (1998) Nat Genet , vol.20 , pp. 66-69
    • Zhuang, Z.1    Park, W.S.2    Pack, S.3
  • 49
    • 0030799090 scopus 로고    scopus 로고
    • Activating mutations for the met tyrosine kinase receptor in human cancer
    • 9326629 1:CAS:528:DyaK2sXmslaku7Y%3D 10.1073/pnas.94.21.11445
    • Jeffers M, Schmidt L, Nakaigawa N, et al. Activating mutations for the met tyrosine kinase receptor in human cancer. Proc Natl Acad Sci USA. 1997;94:11445-50.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 11445-11450
    • Jeffers, M.1    Schmidt, L.2    Nakaigawa, N.3
  • 50
    • 0033535530 scopus 로고    scopus 로고
    • Novel mutations of the MET proto-oncogene in papillary renal carcinomas
    • 10327054 1:CAS:528:DyaK1MXivFKlsr8%3D 10.1038/sj.onc.1202547
    • Schmidt L, Junker K, Nakaigawa N, et al. Novel mutations of the MET proto-oncogene in papillary renal carcinomas. Oncogene. 1999;18:2343-50.
    • (1999) Oncogene , vol.18 , pp. 2343-2350
    • Schmidt, L.1    Junker, K.2    Nakaigawa, N.3
  • 51
    • 0032813906 scopus 로고    scopus 로고
    • Hereditary and sporadic papillary renal carcinomas with c-met mutations share a distinct morphological phenotype
    • 10433944 1:CAS:528:DyaK1MXls1WhsL0%3D 10.1016/S0002-9440(10)65147-4
    • Lubensky IA, Schmidt L, Zhuang Z, et al. Hereditary and sporadic papillary renal carcinomas with c-met mutations share a distinct morphological phenotype. Am J Pathol. 1999;155:517-26.
    • (1999) Am J Pathol , vol.155 , pp. 517-526
    • Lubensky, I.A.1    Schmidt, L.2    Zhuang, Z.3
  • 52
    • 0036286212 scopus 로고    scopus 로고
    • Biological significance of c-met over expression in papillary renal cell carcinoma
    • 12050491 1:CAS:528:DC%2BD38Xlt1Ckur4%3D 10.1016/S0022-5347(05)64830-6
    • Sweeney P, El-Naggar AK, Lin SH, Pisters LL. Biological significance of c-met over expression in papillary renal cell carcinoma. J Urol. 2002;168:51-5.
    • (2002) J Urol , vol.168 , pp. 51-55
    • Sweeney, P.1    El-Naggar, A.K.2    Lin, S.H.3    Pisters, L.L.4
  • 53
    • 65949089138 scopus 로고    scopus 로고
    • Hereditary kidney cancer: Unique opportunity for disease-based therapy
    • 19402075 1:CAS:528:DC%2BD1MXmtVOksbo%3D 10.1002/cncr.24230
    • Linehan WM, Pinto PA, Bratslavsky G, et al. Hereditary kidney cancer: unique opportunity for disease-based therapy. Cancer. 2009;115:2252-61.
    • (2009) Cancer , vol.115 , pp. 2252-2261
    • Linehan, W.M.1    Pinto, P.A.2    Bratslavsky, G.3
  • 54
    • 33846876103 scopus 로고    scopus 로고
    • Identification of the genes for kidney cancer: Opportunity for disease-specific targeted therapeutics
    • 17255292 1:CAS:528:DC%2BD2sXoslSrtQ%3D%3D 10.1158/1078-0432.CCR-06-1870
    • Linehan WM, Pinto PA, Srinivasan R, et al. Identification of the genes for kidney cancer: opportunity for disease-specific targeted therapeutics. Clin Cancer Res. 2007;13:671s-9s.
    • (2007) Clin Cancer Res , vol.13
    • Linehan, W.M.1    Pinto, P.A.2    Srinivasan, R.3
  • 55
    • 4644239258 scopus 로고    scopus 로고
    • Genetic basis of cancer of the kidney: Disease-specific approaches to therapy
    • 15448018 1:CAS:528:DC%2BD2cXnvVOjsLc%3D 10.1158/1078-0432.CCR-050013
    • Linehan WM, Vasselli J, Srinivasan R, et al. Genetic basis of cancer of the kidney: disease-specific approaches to therapy. Clin Cancer Res. 2004;10:6282S-9S.
    • (2004) Clin Cancer Res , vol.10
    • Linehan, W.M.1    Vasselli, J.2    Srinivasan, R.3
  • 56
    • 0037713729 scopus 로고    scopus 로고
    • Mutations in the fumarate hydratase gene cause hereditary leiomyomatosis and renal cell cancer in families in North America
    • 12772087 1:CAS:528:DC%2BD3sXlsVOitLg%3D 10.1086/376435
    • Toro JR, Nickerson ML, Wei MH, et al. Mutations in the fumarate hydratase gene cause hereditary leiomyomatosis and renal cell cancer in families in North America. Am J Hum Genet. 2003;73:95-106.
    • (2003) Am J Hum Genet , vol.73 , pp. 95-106
    • Toro, J.R.1    Nickerson, M.L.2    Wei, M.H.3
  • 57
    • 34249779568 scopus 로고    scopus 로고
    • Temsirolimus, interferon alfa, or both for advanced renal-cell carcinoma
    • 17538086 1:CAS:528:DC%2BD2sXmtVKkurs%3D 10.1056/NEJMoa066838
    • Hudes G, Carducci M, Tomczak P, et al. Temsirolimus, interferon alfa, or both for advanced renal-cell carcinoma. N Engl J Med. 2007;356:2271-81.
    • (2007) N Engl J Med , vol.356 , pp. 2271-2281
    • Hudes, G.1    Carducci, M.2    Tomczak, P.3
  • 58
    • 0033902999 scopus 로고    scopus 로고
    • Phase III trial of interferon alfa-2a with or without 13-cis-retinoic acid for patients with advanced renal cell carcinoma
    • 10944130 1:CAS:528:DC%2BD3cXmsFSktbc%3D
    • Motzer RJ, Murphy BA, Bacik J, et al. Phase III trial of interferon alfa-2a with or without 13-cis-retinoic acid for patients with advanced renal cell carcinoma. J Clin Oncol. 2000;18:2972-80.
    • (2000) J Clin Oncol , vol.18 , pp. 2972-2980
    • Motzer, R.J.1    Murphy, B.A.2    Bacik, J.3
  • 59
    • 33846148701 scopus 로고    scopus 로고
    • Sorafenib in advanced clear-cell renal-cell carcinoma
    • 17215530 1:CAS:528:DC%2BD2sXksVKitg%3D%3D 10.1056/NEJMoa060655
    • Escudier B, Eisen T, Stadler WM, et al. Sorafenib in advanced clear-cell renal-cell carcinoma. N Engl J Med. 2007;356:125-34.
    • (2007) N Engl J Med , vol.356 , pp. 125-134
    • Escudier, B.1    Eisen, T.2    Stadler, W.M.3
  • 60
    • 48649107474 scopus 로고    scopus 로고
    • Efficacy of everolimus in advanced renal cell carcinoma: A double-blind, randomised, placebo-controlled phase III trial
    • 18653228 1:CAS:528:DC%2BD1cXps1GmsLY%3D 10.1016/S0140-6736(08)61039-9
    • Motzer RJ, Escudier B, Oudard S, et al. Efficacy of everolimus in advanced renal cell carcinoma: a double-blind, randomised, placebo-controlled phase III trial. Lancet. 2008;372:449-56.
    • (2008) Lancet , vol.372 , pp. 449-456
    • Motzer, R.J.1    Escudier, B.2    Oudard, S.3
  • 61
    • 33846181370 scopus 로고    scopus 로고
    • Sunitinib versus interferon alfa in metastatic renal-cell carcinoma
    • 17215529 1:CAS:528:DC%2BD2sXksVGqsw%3D%3D 10.1056/NEJMoa065044
    • Motzer RJ, Hutson TE, Tomczak P, et al. Sunitinib versus interferon alfa in metastatic renal-cell carcinoma. N Engl J Med. 2007;356:115-24.
    • (2007) N Engl J Med , vol.356 , pp. 115-124
    • Motzer, R.J.1    Hutson, T.E.2    Tomczak, P.3
  • 62
    • 82755183572 scopus 로고    scopus 로고
    • Comparative effectiveness of axitinib versus sorafenib in advanced renal cell carcinoma (AXIS): A randomised phase 3 trial
    • 22056247 1:CAS:528:DC%2BC3MXhsFGqsL%2FP 10.1016/S0140-6736(11)61613-9
    • Rini BI, Escudier B, Tomczak P, et al. Comparative effectiveness of axitinib versus sorafenib in advanced renal cell carcinoma (AXIS): a randomised phase 3 trial. Lancet. 2011;378:1931-9.
    • (2011) Lancet , vol.378 , pp. 1931-1939
    • Rini, B.I.1    Escudier, B.2    Tomczak, P.3
  • 63
    • 77949890945 scopus 로고    scopus 로고
    • Pazopanib in locally advanced or metastatic renal cell carcinoma: Results of a randomized phase III trial
    • 20100962 1:CAS:528:DC%2BC3cXktF2lt78%3D 10.1200/JCO.2009.23.9764
    • Sternberg CN, Davis ID, Mardiak J, et al. Pazopanib in locally advanced or metastatic renal cell carcinoma: results of a randomized phase III trial. J Clin Oncol. 2010;28:1061-8.
    • (2010) J Clin Oncol , vol.28 , pp. 1061-1068
    • Sternberg, C.N.1    Davis, I.D.2    Mardiak, J.3
  • 64
    • 0021241398 scopus 로고
    • Molecular cloning of a new transforming gene from a chemically transformed human cell line
    • 6590967 1:CAS:528:DyaL2cXmt1ersbk%3D 10.1038/311029a0
    • Cooper CS, Park M, Blair DG, et al. Molecular cloning of a new transforming gene from a chemically transformed human cell line. Nature. 1984;311:29-33.
    • (1984) Nature , vol.311 , pp. 29-33
    • Cooper, C.S.1    Park, M.2    Blair, D.G.3
  • 65
    • 1242348060 scopus 로고
    • Sequence of MET protooncogene cDNA has features characteristic of the tyrosine kinase family of growth-factor receptors
    • 2819873 1:CAS:528:DyaL1cXltVejsw%3D%3D 10.1073/pnas.84.18.6379
    • Park M, Dean M, Kaul K, Braun MJ, Gonda MA, Vande Woude G. Sequence of MET protooncogene cDNA has features characteristic of the tyrosine kinase family of growth-factor receptors. Proc Natl Acad Sci USA. 1987;84:6379-83.
    • (1987) Proc Natl Acad Sci USA , vol.84 , pp. 6379-6383
    • Park, M.1    Dean, M.2    Kaul, K.3    Braun, M.J.4    Gonda, M.A.5    Vande Woude, G.6
  • 66
    • 0024455086 scopus 로고
    • Molecular cloning and sequence analysis of cDNA for human hepatocyte growth factor
    • 2528952 1:CAS:528:DyaK3cXitFWks7k%3D 10.1016/0006-291X(89)92316-4
    • Miyazawa K, Tsubouchi H, Naka D, et al. Molecular cloning and sequence analysis of cDNA for human hepatocyte growth factor. Biochem Biophys Res Commun. 1989;163:967-73.
    • (1989) Biochem Biophys Res Commun , vol.163 , pp. 967-973
    • Miyazawa, K.1    Tsubouchi, H.2    Naka, D.3
  • 67
    • 0024427178 scopus 로고
    • Molecular cloning and expression of human hepatocyte growth factor
    • 2531289 1:CAS:528:DyaK3cXktFyltrc%3D 10.1038/342440a0
    • Nakamura T, Nishizawa T, Hagiya M, et al. Molecular cloning and expression of human hepatocyte growth factor. Nature. 1989;342:440-3.
    • (1989) Nature , vol.342 , pp. 440-443
    • Nakamura, T.1    Nishizawa, T.2    Hagiya, M.3
  • 68
    • 0024356856 scopus 로고
    • Purification and biological characterization of human hepatopoietin A, a polypeptide growth factor for hepatocytes
    • 2524251 1:CAS:528:DyaL1MXktlektrY%3D
    • Zarnegar R, Michalopoulos G. Purification and biological characterization of human hepatopoietin A, a polypeptide growth factor for hepatocytes. Cancer Res. 1989;49:3314-20.
    • (1989) Cancer Res , vol.49 , pp. 3314-3320
    • Zarnegar, R.1    Michalopoulos, G.2
  • 69
    • 0008222162 scopus 로고
    • Purification of scatter factor, a fibroblast-derived basic protein that modulates epithelial interactions and movement
    • 2527367 1:CAS:528:DyaL1MXltV2ksro%3D 10.1073/pnas.86.15.5844
    • Gherardi E, Gray J, Stoker M, Perryman M, Furlong R. Purification of scatter factor, a fibroblast-derived basic protein that modulates epithelial interactions and movement. Proc Natl Acad Sci USA. 1989;86:5844-8.
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 5844-5848
    • Gherardi, E.1    Gray, J.2    Stoker, M.3    Perryman, M.4    Furlong, R.5
  • 70
    • 0023661693 scopus 로고
    • Scatter factor is a fibroblast-derived modulator of epithelial cell mobility
    • 2952888 1:STN:280:DyaL2s3gtF2ltA%3D%3D 10.1038/327239a0
    • Stoker M, Gherardi E, Perryman M, Gray J. Scatter factor is a fibroblast-derived modulator of epithelial cell mobility. Nature. 1987;327:239-42.
    • (1987) Nature , vol.327 , pp. 239-242
    • Stoker, M.1    Gherardi, E.2    Perryman, M.3    Gray, J.4
  • 71
    • 0025351332 scopus 로고
    • Hepatocytes and scatter factor
    • 2142751 1:CAS:528:DyaK3cXltFemt7Y%3D 10.1038/346228b0
    • Gherardi E, Stoker M. Hepatocytes and scatter factor. Nature. 1990;346:228.
    • (1990) Nature , vol.346 , pp. 228
    • Gherardi, E.1    Stoker, M.2
  • 72
    • 0025886454 scopus 로고
    • Evidence for the identity of human scatter factor and human hepatocyte growth factor
    • 1831266 1:CAS:528:DyaK38XlsVelsbY%3D 10.1073/pnas.88.16.7001
    • Weidner KM, Arakaki N, Hartmann G, et al. Evidence for the identity of human scatter factor and human hepatocyte growth factor. Proc Natl Acad Sci USA. 1991;88:7001-5.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 7001-7005
    • Weidner, K.M.1    Arakaki, N.2    Hartmann, G.3
  • 73
    • 0025805633 scopus 로고
    • Identification of the hepatocyte growth factor receptor as the c-met proto-oncogene product
    • 1846706 1:CAS:528:DyaK3MXhtFGku7o%3D 10.1126/science.1846706
    • Bottaro DP, Rubin JS, Faletto DL, et al. Identification of the hepatocyte growth factor receptor as the c-met proto-oncogene product. Science. 1991;251:802-4.
    • (1991) Science , vol.251 , pp. 802-804
    • Bottaro, D.P.1    Rubin, J.S.2    Faletto, D.L.3
  • 75
    • 84856152266 scopus 로고    scopus 로고
    • Targeting MET in cancer: Rationale and progress
    • 22270953 1:CAS:528:DC%2BC38XhtFSmu7s%3D 10.1038/nrc3205 This is an extensive and up-to-date review of MET and the MET pathway and the rationale for targeting it in cancer therapy
    • •• Gherardi E, Birchmeier W, Birchmeier C, Vande Woude G. Targeting MET in cancer: rationale and progress. Nat Rev Cancer. 2012;12:89-103. This is an extensive and up-to-date review of MET and the MET pathway and the rationale for targeting it in cancer therapy.
    • (2012) Nat Rev Cancer , vol.12 , pp. 89-103
    • Gherardi, E.1    Birchmeier, W.2    Birchmeier, C.3    Vande, W.G.4
  • 76
    • 33749367676 scopus 로고    scopus 로고
    • The Met pathway: Master switch and drug target in cancer progression
    • 16873884 1:CAS:528:DC%2BD28Xot1ars7s%3D 10.1096/fj.06-5947rev
    • Mazzone M, Comoglio PM. The Met pathway: master switch and drug target in cancer progression. FASEB J. 2006;20:1611-21.
    • (2006) FASEB J , vol.20 , pp. 1611-1621
    • Mazzone, M.1    Comoglio, P.M.2
  • 77
    • 40849087625 scopus 로고    scopus 로고
    • Molecular cancer therapy: Can our expectation be MET?
    • 18295476 1:CAS:528:DC%2BD1cXjtlWju70%3D 10.1016/j.ejca.2008.01.022
    • Migliore C, Giordano S. Molecular cancer therapy: can our expectation be MET? Eur J Cancer. 2008;44:641-51.
    • (2008) Eur J Cancer , vol.44 , pp. 641-651
    • Migliore, C.1    Giordano, S.2
  • 78
    • 0037478437 scopus 로고    scopus 로고
    • Hypoxia promotes invasive growth by transcriptional activation of the met protooncogene
    • 12726861 10.1016/S1535-6108(03)00085-0
    • Pennacchietti S, Michieli P, Galluzzo M, Mazzone M, Giordano S, Comoglio PM. Hypoxia promotes invasive growth by transcriptional activation of the met protooncogene. Cancer Cell. 2003;3:347-61.
    • (2003) Cancer Cell , vol.3 , pp. 347-361
    • Pennacchietti, S.1    Michieli, P.2    Galluzzo, M.3    Mazzone, M.4    Giordano, S.5    Comoglio, P.M.6
  • 79
    • 0034720310 scopus 로고    scopus 로고
    • The cytokine hepatocyte growth factor/scatter factor inhibits apoptosis and enhances DNA repair by a common mechanism involving signaling through phosphatidyl inositol 3' kinase
    • 10822371 1:CAS:528:DC%2BD3cXjslelsbY%3D 10.1038/sj.onc.1203566
    • Fan S, Ma YX, Wang JA, et al. The cytokine hepatocyte growth factor/scatter factor inhibits apoptosis and enhances DNA repair by a common mechanism involving signaling through phosphatidyl inositol 3' kinase. Oncogene. 2000;19:2212-23.
    • (2000) Oncogene , vol.19 , pp. 2212-2223
    • Fan, S.1    Ma, Y.X.2    Wang, J.A.3
  • 80
    • 84856510440 scopus 로고    scopus 로고
    • MiR-1 downregulation cooperates with MACC1 in promoting MET overexpression in human colon cancer
    • 22179665 1:CAS:528:DC%2BC38XhslOktLg%3D 10.1158/1078-0432.CCR-11-1699
    • Migliore C, Martin V, Leoni VP, et al. MiR-1 downregulation cooperates with MACC1 in promoting MET overexpression in human colon cancer. Clin Cancer Res. 2012;18:737-47.
    • (2012) Clin Cancer Res , vol.18 , pp. 737-747
    • Migliore, C.1    Martin, V.2    Leoni, V.P.3
  • 81
    • 84861733799 scopus 로고    scopus 로고
    • MET: A promising anticancer therapeutic target
    • 22566105 1:CAS:528:DC%2BC38XnvVOrtL0%3D 10.1038/nrclinonc.2012.71 This is a timely and extensive review of the MET pathway and the drugs currently under development which target it
    • •• Peters S, Adjei AA. MET: a promising anticancer therapeutic target. Nat Rev Clin Oncol. 2012;9:314-26. This is a timely and extensive review of the MET pathway and the drugs currently under development which target it.
    • (2012) Nat Rev Clin Oncol , vol.9 , pp. 314-326
    • Peters, S.1    Adjei, A.A.2
  • 82
    • 44449151030 scopus 로고    scopus 로고
    • Drug development of MET inhibitors: Targeting oncogene addiction and expedience
    • 18511928 1:CAS:528:DC%2BD1cXmsVOjsb0%3D 10.1038/nrd2530
    • Comoglio PM, Giordano S, Trusolino L. Drug development of MET inhibitors: targeting oncogene addiction and expedience. Nat Rev Drug Discov. 2008;7:504-16.
    • (2008) Nat Rev Drug Discov , vol.7 , pp. 504-516
    • Comoglio, P.M.1    Giordano, S.2    Trusolino, L.3
  • 83
    • 19544389146 scopus 로고    scopus 로고
    • C-Met as a target for human cancer and characterization of inhibitors for therapeutic intervention
    • 15922853 1:CAS:528:DC%2BD2MXks1Ggs7c%3D 10.1016/j.canlet.2004.09.044
    • Christensen JG, Burrows J, Salgia R. c-Met as a target for human cancer and characterization of inhibitors for therapeutic intervention. Cancer Lett. 2005;225:1-26.
    • (2005) Cancer Lett , vol.225 , pp. 1-26
    • Christensen, J.G.1    Burrows, J.2    Salgia, R.3
  • 84
    • 65249122512 scopus 로고    scopus 로고
    • Novel therapeutic inhibitors of the c-Met signaling pathway in cancer
    • 19318488 1:CAS:528:DC%2BD1MXjvVWltrY%3D 10.1158/1078-0432.CCR-08-1306
    • Eder JP, Vande Woude GF, Boerner SA, LoRusso PM. Novel therapeutic inhibitors of the c-Met signaling pathway in cancer. Clin Cancer Res. 2009;15:2207-14.
    • (2009) Clin Cancer Res , vol.15 , pp. 2207-2214
    • Eder, J.P.1    Vande Woude, G.F.2    Boerner, S.A.3    Lorusso, P.M.4
  • 85
    • 77954236265 scopus 로고    scopus 로고
    • A phase i study of foretinib, a multi-targeted inhibitor of c-Met and vascular endothelial growth factor receptor 2
    • 20472683 1:CAS:528:DC%2BC3cXot1Wlt74%3D 10.1158/1078-0432.CCR-10-0574 This is a phase I study of foretinib in 40 cancer patients. Two papillary RCC patients responded
    • •• Eder JP, Shapiro GI, Appleman LJ, et al. A phase I study of foretinib, a multi-targeted inhibitor of c-Met and vascular endothelial growth factor receptor 2. Clin Cancer Res. 2010;16:3507-16. This is a phase I study of foretinib in 40 cancer patients. Two papillary RCC patients responded.
    • (2010) Clin Cancer Res , vol.16 , pp. 3507-3516
    • Eder, J.P.1    Shapiro, G.I.2    Appleman, L.J.3
  • 86
    • 70350230210 scopus 로고    scopus 로고
    • Inhibition of tumor cell growth, invasion, and metastasis by EXEL-2880 (XL880, GSK1363089), a novel inhibitor of HGF and VEGF receptor tyrosine kinases
    • 19808973 1:CAS:528:DC%2BD1MXht1ynurbF 10.1158/0008-5472.CAN-08-4889
    • Qian F, Engst S, Yamaguchi K, et al. Inhibition of tumor cell growth, invasion, and metastasis by EXEL-2880 (XL880, GSK1363089), a novel inhibitor of HGF and VEGF receptor tyrosine kinases. Cancer Res. 2009;69:8009-16.
    • (2009) Cancer Res , vol.69 , pp. 8009-8016
    • Qian, F.1    Engst, S.2    Yamaguchi, K.3
  • 87
    • 0038172576 scopus 로고    scopus 로고
    • Cancer: Out of air is not out of action
    • 12789320 1:CAS:528:DC%2BD3sXkt1ykuro%3D 10.1038/423593a
    • Bottaro DP, Liotta LA. Cancer: out of air is not out of action. Nature. 2003;423:593-5.
    • (2003) Nature , vol.423 , pp. 593-595
    • Bottaro, D.P.1    Liotta, L.A.2
  • 88
    • 77954238997 scopus 로고    scopus 로고
    • Reduction of tumor invasiveness and metastasis and prolongation of survival of RIP-TAG2 mice after inhibition of VEGFR plus C-met by XL184
    • 10.1158/1535-7163.TARG-09-A13
    • Sennino B, Naylor RM, Tabruyn SP. Reduction of tumor invasiveness and metastasis and prolongation of survival of RIP-TAG2 mice after inhibition of VEGFR plus C-met by XL184. Mol Cancer Ther. 2009;8(12 Suppl):A13.
    • (2009) Mol Cancer Ther , vol.8 , Issue.12 SUPPL. , pp. 13
    • Sennino, B.1    Naylor, R.M.2    Tabruyn, S.P.3
  • 89
    • 79960408937 scopus 로고    scopus 로고
    • VEGF and c-Met blockade amplify angiogenesis inhibition in pancreatic islet cancer
    • 21613405 1:CAS:528:DC%2BC3MXovFarsLY%3D 10.1158/0008-5472.CAN-10-2527
    • You WK, Sennino B, Williamson CW, et al. VEGF and c-Met blockade amplify angiogenesis inhibition in pancreatic islet cancer. Cancer Res. 2011;71:4758-68.
    • (2011) Cancer Res , vol.71 , pp. 4758-4768
    • You, W.K.1    Sennino, B.2    Williamson, C.W.3
  • 90
    • 84861535274 scopus 로고    scopus 로고
    • Foretinib demonstrates anti-tumor activity and improves overall survival in preclinical models of hepatocellular carcinoma
    • 22187171 1:CAS:528:DC%2BC38XitFGgsbg%3D 10.1007/s10456-011-9243-z
    • Huynh H, Ong R, Soo KC. Foretinib demonstrates anti-tumor activity and improves overall survival in preclinical models of hepatocellular carcinoma. Angiogenesis. 2012;15:59-70.
    • (2012) Angiogenesis , vol.15 , pp. 59-70
    • Huynh, H.1    Ong, R.2    Soo, K.C.3
  • 91
    • 84866738718 scopus 로고    scopus 로고
    • Foretinib (GSK1363089), a multi-kinase inhibitor of MET and VEGFRs, inhibits growth of gastric cancer cell lines by blocking inter-receptor tyrosine kinase networks
    • 21655918 1:CAS:528:DC%2BC38XpvVyks7s%3D 10.1007/s10637-011-9699-0
    • Kataoka Y, Mukohara T, Tomioka H, et al. Foretinib (GSK1363089), a multi-kinase inhibitor of MET and VEGFRs, inhibits growth of gastric cancer cell lines by blocking inter-receptor tyrosine kinase networks. Invest New Drugs. 2012;30:1352-60.
    • (2012) Invest New Drugs , vol.30 , pp. 1352-1360
    • Kataoka, Y.1    Mukohara, T.2    Tomioka, H.3
  • 92
    • 79955781270 scopus 로고    scopus 로고
    • Synergistic effects of foretinib with HER-targeted agents in MET and HER1- or HER2-coactivated tumor cells
    • 21252284 1:CAS:528:DC%2BC3MXivVCrsrg%3D 10.1158/1535-7163.MCT-10-0698
    • Liu L, Shi H, Liu Y, et al. Synergistic effects of foretinib with HER-targeted agents in MET and HER1- or HER2-coactivated tumor cells. Mol Cancer Ther. 2011;10:518-30.
    • (2011) Mol Cancer Ther , vol.10 , pp. 518-530
    • Liu, L.1    Shi, H.2    Liu, Y.3
  • 93
    • 79959215032 scopus 로고    scopus 로고
    • Foretinib (GSK1363089), an orally available multikinase inhibitor of c-Met and VEGFR-2, blocks proliferation, induces anoikis, and impairs ovarian cancer metastasis
    • 21551255 1:CAS:528:DC%2BC3MXnsFKgt70%3D 10.1158/1078-0432.CCR-10-3387
    • Zillhardt M, Park SM, Romero IL, et al. Foretinib (GSK1363089), an orally available multikinase inhibitor of c-Met and VEGFR-2, blocks proliferation, induces anoikis, and impairs ovarian cancer metastasis. Clin Cancer Res. 2011;17:4042-51.
    • (2011) Clin Cancer Res , vol.17 , pp. 4042-4051
    • Zillhardt, M.1    Park, S.M.2    Romero, I.L.3
  • 94
    • 48249129217 scopus 로고    scopus 로고
    • A phase i dose-escalation study of the safety, pharmacokinetics (PK) and pharmacodynamics of XL880, A VEGFR and MET kinase inhibitor, administered daily to patients with advanced malignancies
    • abstract B248
    • Shapiro GI, Heath E, Malburg L. A phase I dose-escalation study of the safety, pharmacokinetics (PK) and pharmacodynamics of XL880, A VEGFR and MET kinase inhibitor, administered daily to patients with advanced malignancies. AACR-NCI-EORTC Molecular Targets and Cancer Therapeutics Meeting 2007 abstract B248.
    • (2007) AACR-NCI-EORTC Molecular Targets and Cancer Therapeutics Meeting
    • Shapiro, G.I.1    Heath, E.2    Malburg, L.3
  • 95
    • 84856540747 scopus 로고    scopus 로고
    • A comparison of the pharmacokinetics of the anticancer MET inhibitor foretinib free base tablet formulation to bisphosphate salt capsule formulation in patients with solid tumors
    • 20842406 1:CAS:528:DC%2BC38XotVWgtg%3D%3D 10.1007/s10637-010-9536-x
    • Naing A, Kurzrock R, Adams LM, et al. A comparison of the pharmacokinetics of the anticancer MET inhibitor foretinib free base tablet formulation to bisphosphate salt capsule formulation in patients with solid tumors. Invest New Drugs. 2012;30:327-34.
    • (2012) Invest New Drugs , vol.30 , pp. 327-334
    • Naing, A.1    Kurzrock, R.2    Adams, L.M.3
  • 96
    • 84872548337 scopus 로고    scopus 로고
    • A phase II and biomarker study of the dual MET/VEGFR-2 inhibitor foretinib in patients with papillary renal cell cancer
    • 23213094 1:CAS:528:DC%2BC3sXhvV2gsrs%3D 10.1200/JCO.2012.43.3383 This is the phase II study of foretinib in papillary RCC
    • •• Choueiri TK, Vaishampayan U, Rosenberg JE, et al. A phase II and biomarker study of the dual MET/VEGFR-2 inhibitor foretinib in patients with papillary renal cell cancer. J Clin Oncol. 2013;31:181-6. This is the phase II study of foretinib in papillary RCC.
    • (2013) J Clin Oncol , vol.31 , pp. 181-186
    • Choueiri, T.K.1    Vaishampayan, U.2    Rosenberg, J.E.3
  • 97
    • 0036138580 scopus 로고    scopus 로고
    • Interferon-alfa as a comparative treatment for clinical trials of new therapies against advanced renal cell carcinoma
    • 11773181 1:CAS:528:DC%2BD38XnsFeqtg%3D%3D 10.1200/JCO.20.1.289
    • Motzer RJ, Bacik J, Murphy BA, Russo P, Mazumdar M. Interferon-alfa as a comparative treatment for clinical trials of new therapies against advanced renal cell carcinoma. J Clin Oncol. 2002;20:289-96.
    • (2002) J Clin Oncol , vol.20 , pp. 289-296
    • Motzer, R.J.1    Bacik, J.2    Murphy, B.A.3    Russo, P.4    Mazumdar, M.5
  • 98
    • 33751565698 scopus 로고    scopus 로고
    • Treatment outcome for metastatic papillary renal cell carcinoma patients
    • 17083126 1:CAS:528:DC%2BD28XhtlCmu7jE 10.1002/cncr.22340
    • Ronnen EA, Kondagunta GV, Ishill N, et al. Treatment outcome for metastatic papillary renal cell carcinoma patients. Cancer. 2006;107:2617-21.
    • (2006) Cancer , vol.107 , pp. 2617-2621
    • Ronnen, E.A.1    Kondagunta, G.V.2    Ishill, N.3
  • 99
    • 37849001813 scopus 로고    scopus 로고
    • Efficacy of sunitinib and sorafenib in metastatic papillary and chromophobe renal cell carcinoma
    • 18165647 1:CAS:528:DC%2BD1cXhsVCrtr4%3D 10.1200/JCO.2007.13.3223
    • Choueiri TK, Plantade A, Elson P, et al. Efficacy of sunitinib and sorafenib in metastatic papillary and chromophobe renal cell carcinoma. J Clin Oncol. 2008;26:127-31.
    • (2008) J Clin Oncol , vol.26 , pp. 127-131
    • Choueiri, T.K.1    Plantade, A.2    Elson, P.3
  • 100
    • 65249089759 scopus 로고    scopus 로고
    • Phase II trial of carboplatin and paclitaxel in papillary renal cell carcinoma
    • 19213667 1:CAS:528:DC%2BD1MXjslKqsL8%3D 10.3816/CGC.2009.n.007
    • Bylow KA, Atkins MB, Posadas EM, Stadler WM, McDermott DF. Phase II trial of carboplatin and paclitaxel in papillary renal cell carcinoma. Clin Genitourin Cancer. 2009;7:39-42.
    • (2009) Clin Genitourin Cancer , vol.7 , pp. 39-42
    • Bylow, K.A.1    Atkins, M.B.2    Posadas, E.M.3    Stadler, W.M.4    McDermott, D.F.5
  • 101
    • 73349085260 scopus 로고    scopus 로고
    • Phase II study of erlotinib in patients with locally advanced or metastatic papillary histology renal cell cancer: SWOG S0317
    • 19884559 1:CAS:528:DC%2BC3cXhtVWisbc%3D 10.1200/JCO.2008.18.8821
    • Gordon MS, Hussey M, Nagle RB, et al. Phase II study of erlotinib in patients with locally advanced or metastatic papillary histology renal cell cancer: SWOG S0317. J Clin Oncol. 2009;27:5788-93.
    • (2009) J Clin Oncol , vol.27 , pp. 5788-5793
    • Gordon, M.S.1    Hussey, M.2    Nagle, R.B.3
  • 102
    • 84861530844 scopus 로고    scopus 로고
    • Phase II, multicenter, uncontrolled trial of single-agent capecitabine in patients with non-clear cell metastatic renal cell carcinoma
    • 21358295 1:CAS:528:DC%2BC38XnsVCisLk%3D 10.1097/COC.0b013e31820dbc17
    • Tsimafeyeu I, Demidov L, Kharkevich G, et al. Phase II, multicenter, uncontrolled trial of single-agent capecitabine in patients with non-clear cell metastatic renal cell carcinoma. Am J Clin Oncol. 2012;35:251-4.
    • (2012) Am J Clin Oncol , vol.35 , pp. 251-254
    • Tsimafeyeu, I.1    Demidov, L.2    Kharkevich, G.3
  • 103
    • 84868532639 scopus 로고    scopus 로고
    • A phase 2 trial of sunitinib in patients with advanced non-clear cell renal cell carcinoma
    • 22771265 1:CAS:528:DC%2BC38XpvFGitbc%3D 10.1016/j.eururo.2012.06.043
    • Tannir NM, Plimack E, Ng C, et al. A phase 2 trial of sunitinib in patients with advanced non-clear cell renal cell carcinoma. Eur Urol. 2012;62:1013-9.
    • (2012) Eur Urol , vol.62 , pp. 1013-1019
    • Tannir, N.M.1    Plimack, E.2    Ng, C.3
  • 104
    • 84856550225 scopus 로고    scopus 로고
    • Phase II trial of sunitinib in patients with metastatic non-clear cell renal cell carcinoma
    • 20711632 1:CAS:528:DC%2BC38XotVWitw%3D%3D 10.1007/s10637-010-9491-6
    • Molina AM, Feldman DR, Ginsberg MS, et al. Phase II trial of sunitinib in patients with metastatic non-clear cell renal cell carcinoma. Invest New Drugs. 2012;30:335-40.
    • (2012) Invest New Drugs , vol.30 , pp. 335-340
    • Molina, A.M.1    Feldman, D.R.2    Ginsberg, M.S.3
  • 105
    • 79960375009 scopus 로고    scopus 로고
    • Multicenter prospective phase II study of sunitinib in non-clear cell type renal cell carcinoma
    • abstr 325
    • Lee J, Ahn J, Lim H. Multicenter prospective phase II study of sunitinib in non-clear cell type renal cell carcinoma. J Clin Oncol. 2011;29(Suppl 7):abstr 325.
    • (2011) J Clin Oncol , vol.29 , Issue.SUPPL. 7
    • Lee, J.1    Ahn, J.2    Lim, H.3
  • 106
    • 67651056360 scopus 로고    scopus 로고
    • Effect of temsirolimus versus interferon-alpha on outcome of patients with advanced renal cell carcinoma of different tumor histologies
    • 19229667 1:CAS:528:DC%2BD1MXmtVKitr0%3D 10.1007/s12032-009-9177-0
    • Dutcher JP, de Souza P, McDermott D, et al. Effect of temsirolimus versus interferon-alpha on outcome of patients with advanced renal cell carcinoma of different tumor histologies. Med Oncol. 2009;26:202-9.
    • (2009) Med Oncol , vol.26 , pp. 202-209
    • Dutcher, J.P.1    De Souza, P.2    McDermott, D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.