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Volumn 23, Issue 6, 2012, Pages 357-365

Neurotrophins and their receptors in breast cancer

Author keywords

Biomarkers; Breast cancer; Neurotrophins; Therapeutic targets; Tumor growth and metastasis

Indexed keywords

ANTINEOPLASTIC AGENT; AZ 23; AZD 6918; BRAIN DERIVED NEUROTROPHIC FACTOR; BRAIN DERIVED NEUROTROPHIC FACTOR RECEPTOR; CEP 2563; CEP 751; ENDOCANNABINOID; EPIDERMAL GROWTH FACTOR RECEPTOR 2; GNF 5837; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; KU ANTIGEN; LESTAURTINIB; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; NERVE GROWTH FACTOR; NERVE GROWTH FACTOR ANTIBODY; NEUROTROPHIN; NEUROTROPHIN 4; NEUROTROPHIN RECEPTOR; NEUROTROPHIN RECEPTOR P75; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PROTEIN TYROSINE KINASE A; PROTEIN TYROSINE PHOSPHATASE SHP 1; TAMOXIFEN; TANEZUMAB; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED DEATH DOMAIN PROTEIN; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 4; UNCLASSIFIED DRUG; UNINDEXED DRUG;

EID: 84869884311     PISSN: 13596101     EISSN: 18790305     Source Type: Journal    
DOI: 10.1016/j.cytogfr.2012.06.004     Document Type: Short Survey
Times cited : (96)

References (105)
  • 3
    • 57149146434 scopus 로고    scopus 로고
    • The role of endocrine insulin-like growth factor-I and insulin in breast cancer
    • Lann D., LeRoith D. The role of endocrine insulin-like growth factor-I and insulin in breast cancer. Journal of Mammary Gland Biology and Neoplasia 2008, 13:371-379.
    • (2008) Journal of Mammary Gland Biology and Neoplasia , vol.13 , pp. 371-379
    • Lann, D.1    LeRoith, D.2
  • 4
    • 77954365472 scopus 로고    scopus 로고
    • Potential for targeting the fibroblast growth factor receptors in breast cancer
    • Hynes N.E., Dey J.H. Potential for targeting the fibroblast growth factor receptors in breast cancer. Cancer Research 2010, 70:5199-5202.
    • (2010) Cancer Research , vol.70 , pp. 5199-5202
    • Hynes, N.E.1    Dey, J.H.2
  • 6
    • 77954014147 scopus 로고    scopus 로고
    • Trastuzumab-based neoadjuvant therapy in patients with HER2-positive breast cancer
    • Chang H.R. Trastuzumab-based neoadjuvant therapy in patients with HER2-positive breast cancer. Cancer 2010, 116:2856-2867.
    • (2010) Cancer , vol.116 , pp. 2856-2867
    • Chang, H.R.1
  • 7
    • 80054109854 scopus 로고    scopus 로고
    • Trastuzumab emtansine in human epidermal growth factor receptor 2-positive breast cancer: a review
    • Mathew J., Perez E.A. Trastuzumab emtansine in human epidermal growth factor receptor 2-positive breast cancer: a review. Current Opinion in Oncology 2011, 23:594-600.
    • (2011) Current Opinion in Oncology , vol.23 , pp. 594-600
    • Mathew, J.1    Perez, E.A.2
  • 9
    • 81555216077 scopus 로고    scopus 로고
    • Gene expression profiling in breast cancer: classification, prognostication, and prediction
    • Reis-Filho J.S., Pusztai L. Gene expression profiling in breast cancer: classification, prognostication, and prediction. Lancet 2011, 378:1812-1823.
    • (2011) Lancet , vol.378 , pp. 1812-1823
    • Reis-Filho, J.S.1    Pusztai, L.2
  • 11
    • 77949271600 scopus 로고    scopus 로고
    • Management of breast cancer with targeted agents: importance of heterogeneity
    • Di Cosimo S., Baselga J. Management of breast cancer with targeted agents: importance of heterogeneity. Nature Reviews Clinical Oncology 2010, 7:139-147.
    • (2010) Nature Reviews Clinical Oncology , vol.7 , pp. 139-147
    • Di Cosimo, S.1    Baselga, J.2
  • 12
    • 84859879356 scopus 로고    scopus 로고
    • The neurotrophin family of neurotrophic factors: an overview
    • Skaper S.D. The neurotrophin family of neurotrophic factors: an overview. Methods in Molecular Biology 2012, 846:1-12.
    • (2012) Methods in Molecular Biology , vol.846 , pp. 1-12
    • Skaper, S.D.1
  • 14
    • 77949729496 scopus 로고    scopus 로고
    • Understanding proneurotrophin actions: recent advances and challenges
    • Teng K.K., Felice S., Kim T., Hempstead B.L. Understanding proneurotrophin actions: recent advances and challenges. Developmental Neurobiology 2010, 70:350-359.
    • (2010) Developmental Neurobiology , vol.70 , pp. 350-359
    • Teng, K.K.1    Felice, S.2    Kim, T.3    Hempstead, B.L.4
  • 15
    • 77949721758 scopus 로고    scopus 로고
    • Neurotrophin receptors: old friends with new partners
    • Schecterson L.C., Bothwell M. Neurotrophin receptors: old friends with new partners. Developmental Neurobiology 2010, 70:332-338.
    • (2010) Developmental Neurobiology , vol.70 , pp. 332-338
    • Schecterson, L.C.1    Bothwell, M.2
  • 16
    • 84859267166 scopus 로고    scopus 로고
    • Sortilin: a receptor to regulate neuronal viability and function
    • Nykjaer A., Willnow T.E. Sortilin: a receptor to regulate neuronal viability and function. Trends in Neurosciences 2012, 35:261-270.
    • (2012) Trends in Neurosciences , vol.35 , pp. 261-270
    • Nykjaer, A.1    Willnow, T.E.2
  • 19
    • 0004594704 scopus 로고    scopus 로고
    • Nerve growth factor stimulates proliferation and survival of human breast cancer cells through two distinct signaling pathways
    • Descamps S., Toillon R.A., Adriaenssens E., Pawlowski V., Cool S.M., Nurcombe V., et al. Nerve growth factor stimulates proliferation and survival of human breast cancer cells through two distinct signaling pathways. Journal of Biological Chemistry 2001, 276:17864-17870.
    • (2001) Journal of Biological Chemistry , vol.276 , pp. 17864-17870
    • Descamps, S.1    Toillon, R.A.2    Adriaenssens, E.3    Pawlowski, V.4    Cool, S.M.5    Nurcombe, V.6
  • 20
    • 0037593903 scopus 로고    scopus 로고
    • Tumor necrosis factor receptor-associated death domain protein is involved in the neurotrophin receptor-mediated antiapoptotic activity of nerve growth factor in breast cancer cells
    • El Yazidi-Belkoura I., Adriaenssens E., Dollé L., Descamps S., Hondermarck H. Tumor necrosis factor receptor-associated death domain protein is involved in the neurotrophin receptor-mediated antiapoptotic activity of nerve growth factor in breast cancer cells. Journal of Biological Chemistry 2003, 278:16952-16956.
    • (2003) Journal of Biological Chemistry , vol.278 , pp. 16952-16956
    • El Yazidi-Belkoura, I.1    Adriaenssens, E.2    Dollé, L.3    Descamps, S.4    Hondermarck, H.5
  • 23
    • 0034465259 scopus 로고    scopus 로고
    • Suppression of nerve growth factor Trk receptors and prolactin receptors by endocannabinoids leads to inhibition of human breast and prostate cancer cell proliferation
    • Melck D., De Petrocellis L., Orlando P., Bisogno T., Laezza C., Bifulco M., et al. Suppression of nerve growth factor Trk receptors and prolactin receptors by endocannabinoids leads to inhibition of human breast and prostate cancer cell proliferation. Endocrinology 2000, 141:118-126.
    • (2000) Endocrinology , vol.141 , pp. 118-126
    • Melck, D.1    De Petrocellis, L.2    Orlando, P.3    Bisogno, T.4    Laezza, C.5    Bifulco, M.6
  • 24
    • 0035300597 scopus 로고    scopus 로고
    • Tamoxifen inhibits nerve growth factor-induced proliferation of the human breast cancerous cell line MCF-7
    • Chiarenza A., Lazarovici P., Lempereur L., Cantarella G., Bianchi A., Bernardini R. Tamoxifen inhibits nerve growth factor-induced proliferation of the human breast cancerous cell line MCF-7. Cancer Research 2001, 61:3002-3008.
    • (2001) Cancer Research , vol.61 , pp. 3002-3008
    • Chiarenza, A.1    Lazarovici, P.2    Lempereur, L.3    Cantarella, G.4    Bianchi, A.5    Bernardini, R.6
  • 25
    • 0035360866 scopus 로고    scopus 로고
    • Expression of nerve growth factor receptors and their prognostic value in human breast cancer
    • Descamps S., Pawlowski V., Revillion F., Hornez L., Hebbar M., Boilly B., et al. Expression of nerve growth factor receptors and their prognostic value in human breast cancer. Cancer Research 2001, 61:4337-4340.
    • (2001) Cancer Research , vol.61 , pp. 4337-4340
    • Descamps, S.1    Pawlowski, V.2    Revillion, F.3    Hornez, L.4    Hebbar, M.5    Boilly, B.6
  • 28
    • 0742304068 scopus 로고    scopus 로고
    • Altered expression and activation of the nerve growth factor receptors TrkA and p75 provide the first evidence of tumor progression to effusion in breast carcinoma
    • Davidson B., Reich R., Lazarovici P., Ann Florenes V., Nielsen S., Nesland J.M. Altered expression and activation of the nerve growth factor receptors TrkA and p75 provide the first evidence of tumor progression to effusion in breast carcinoma. Breast Cancer Research and Treatment 2004, 83:119-128.
    • (2004) Breast Cancer Research and Treatment , vol.83 , pp. 119-128
    • Davidson, B.1    Reich, R.2    Lazarovici, P.3    Ann Florenes, V.4    Nielsen, S.5    Nesland, J.M.6
  • 29
    • 66149157927 scopus 로고    scopus 로고
    • TrkA overexpression enhances growth and metastasis of breast cancer cells
    • Lagadec C., Meignan S., Adriaenssens E., Foveau B., Vanhecke E., Romon R., et al. TrkA overexpression enhances growth and metastasis of breast cancer cells. Oncogene 2009, 28:1960-1970.
    • (2009) Oncogene , vol.28 , pp. 1960-1970
    • Lagadec, C.1    Meignan, S.2    Adriaenssens, E.3    Foveau, B.4    Vanhecke, E.5    Romon, R.6
  • 32
    • 70350632734 scopus 로고    scopus 로고
    • Repression of SHP-1 expression by p53 leads to trkA tyrosine phosphorylation and suppression of breast cancer cell proliferation
    • Montano X. Repression of SHP-1 expression by p53 leads to trkA tyrosine phosphorylation and suppression of breast cancer cell proliferation. Oncogene 2009, 28:3787-3800.
    • (2009) Oncogene , vol.28 , pp. 3787-3800
    • Montano, X.1
  • 33
    • 34547110396 scopus 로고    scopus 로고
    • BEX2 is overexpressed in a subset of primary breast cancers and mediates nerve growth factor/nuclear factor-kappaB inhibition of apoptosis in breast cancer cell lines
    • Naderi A., Teschendorff A.E., Beigel J., Cariati M., Ellis I.O., Brenton J.D., et al. BEX2 is overexpressed in a subset of primary breast cancers and mediates nerve growth factor/nuclear factor-kappaB inhibition of apoptosis in breast cancer cell lines. Cancer Research 2007, 67:6725-6736.
    • (2007) Cancer Research , vol.67 , pp. 6725-6736
    • Naderi, A.1    Teschendorff, A.E.2    Beigel, J.3    Cariati, M.4    Ellis, I.O.5    Brenton, J.D.6
  • 34
    • 65849368486 scopus 로고    scopus 로고
    • Nerve growth factor/nuclear factor-kappaB pathway as a therapeutic target in breast cancer
    • Naderi A., Hughes-Davies L. Nerve growth factor/nuclear factor-kappaB pathway as a therapeutic target in breast cancer. Journal of Cancer Research and Clinical Oncology 2009, 135:211-216.
    • (2009) Journal of Cancer Research and Clinical Oncology , vol.135 , pp. 211-216
    • Naderi, A.1    Hughes-Davies, L.2
  • 36
    • 70349659954 scopus 로고    scopus 로고
    • On Trk - the TrkB signal transduction pathway is an increasingly important target in cancer biology
    • Thiele C.J., Li Z., McKee A.E. On Trk - the TrkB signal transduction pathway is an increasingly important target in cancer biology. Clinical Cancer Research 2009, 15:5962-5967.
    • (2009) Clinical Cancer Research , vol.15 , pp. 5962-5967
    • Thiele, C.J.1    Li, Z.2    McKee, A.E.3
  • 38
    • 39749121408 scopus 로고    scopus 로고
    • Dieldrin promotes resistance to anoikis in breast cancer cells in vitro
    • Cameron H.L., Foster W.G. Dieldrin promotes resistance to anoikis in breast cancer cells in vitro. Reproductive Toxicology 2008, 25:256-262.
    • (2008) Reproductive Toxicology , vol.25 , pp. 256-262
    • Cameron, H.L.1    Foster, W.G.2
  • 39
    • 59549097224 scopus 로고    scopus 로고
    • Developmental and lactational exposure to dieldrin alters mammary tumorigenesis in Her2/neu transgenic mice
    • Cameron H.L., Foster W.G. Developmental and lactational exposure to dieldrin alters mammary tumorigenesis in Her2/neu transgenic mice. PLoS One 2009, 4:e4303.
    • (2009) PLoS One , vol.4
    • Cameron, H.L.1    Foster, W.G.2
  • 40
    • 79953300722 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor and neurotrophin-4/5 are expressed in breast cancer and can be targeted to inhibit tumor cell survival
    • Vanhecke E., Adriaenssens E., Verbeke S., Meignan S., Germain E., Berteaux N., et al. Brain-derived neurotrophic factor and neurotrophin-4/5 are expressed in breast cancer and can be targeted to inhibit tumor cell survival. Clinical Cancer Research 2011, 17:1741-1752.
    • (2011) Clinical Cancer Research , vol.17 , pp. 1741-1752
    • Vanhecke, E.1    Adriaenssens, E.2    Verbeke, S.3    Meignan, S.4    Germain, E.5    Berteaux, N.6
  • 41
    • 79960557212 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor expression predicts adverse pathological & clinical outcomes in human breast cancer
    • Patani N., Jiang W.G., Mokbel K. Brain-derived neurotrophic factor expression predicts adverse pathological & clinical outcomes in human breast cancer. Cancer Cell International 2011, 11:23.
    • (2011) Cancer Cell International , vol.11 , pp. 23
    • Patani, N.1    Jiang, W.G.2    Mokbel, K.3
  • 42
    • 33846815516 scopus 로고    scopus 로고
    • Identification of novel genes that co-cluster with estrogen receptor alpha in breast tumor biopsy specimens, using a large-scale real-time reverse transcription-PCR approach
    • Tozlu S., Girault I., Vacher S., Vendrell J., Andrieu C., Spyratos F., et al. Identification of novel genes that co-cluster with estrogen receptor alpha in breast tumor biopsy specimens, using a large-scale real-time reverse transcription-PCR approach. Endocrine-Related Cancer 2006, 13:1109-1120.
    • (2006) Endocrine-Related Cancer , vol.13 , pp. 1109-1120
    • Tozlu, S.1    Girault, I.2    Vacher, S.3    Vendrell, J.4    Andrieu, C.5    Spyratos, F.6
  • 43
    • 84858332188 scopus 로고    scopus 로고
    • Truncated TrkB: beyond a dominant negative receptor
    • Fenner B.M. Truncated TrkB: beyond a dominant negative receptor. Cytokine and Growth Factor Reviews 2012, 23:15-24.
    • (2012) Cytokine and Growth Factor Reviews , vol.23 , pp. 15-24
    • Fenner, B.M.1
  • 44
    • 79955102595 scopus 로고    scopus 로고
    • Targets of miR-200c mediate suppression of cell motility and anoikis resistance
    • Howe E.N., Cochrane D.R., Richer J.K. Targets of miR-200c mediate suppression of cell motility and anoikis resistance. Breast Cancer Research 2011, 13:R45.
    • (2011) Breast Cancer Research , vol.13
    • Howe, E.N.1    Cochrane, D.R.2    Richer, J.K.3
  • 45
    • 10744219632 scopus 로고    scopus 로고
    • Sortilin is essential for proNGF-induced neuronal cell death
    • Nykjaer A., Lee R., Teng K.K., Jansen P., Madsen P., Nielsen M.S., et al. Sortilin is essential for proNGF-induced neuronal cell death. Nature 2004, 427:843-848.
    • (2004) Nature , vol.427 , pp. 843-848
    • Nykjaer, A.1    Lee, R.2    Teng, K.K.3    Jansen, P.4    Madsen, P.5    Nielsen, M.S.6
  • 47
    • 84855833498 scopus 로고    scopus 로고
    • Pro-nerve growth factor induces autocrine stimulation of breast cancer cell invasion through tropomyosin-related kinase A (TrkA) and sortilin protein
    • Demont Y., Corbet C., Page A., Ataman-önal Y., Choquet-Kastylevsky G., Fliniaux I., et al. Pro-nerve growth factor induces autocrine stimulation of breast cancer cell invasion through tropomyosin-related kinase A (TrkA) and sortilin protein. Journal of Biological Chemistry 2012, 287:1923-1931.
    • (2012) Journal of Biological Chemistry , vol.287 , pp. 1923-1931
    • Demont, Y.1    Corbet, C.2    Page, A.3    Ataman-önal, Y.4    Choquet-Kastylevsky, G.5    Fliniaux, I.6
  • 48
    • 38349103370 scopus 로고    scopus 로고
    • C-Src is required for tropomyosin receptor kinase C (TrkC)-induced activation of the phosphatidylinositol 3-kinase (PI3K)-AKT pathway
    • Jin W., Yun C., Jeong J., Park Y., Lee H.D., Kim S.J. c-Src is required for tropomyosin receptor kinase C (TrkC)-induced activation of the phosphatidylinositol 3-kinase (PI3K)-AKT pathway. Journal of Biological Chemistry 2008, 283(3):1391-1400.
    • (2008) Journal of Biological Chemistry , vol.283 , Issue.3 , pp. 1391-1400
    • Jin, W.1    Yun, C.2    Jeong, J.3    Park, Y.4    Lee, H.D.5    Kim, S.J.6
  • 49
    • 78149274357 scopus 로고    scopus 로고
    • TrkC plays an essential role in breast tumor growth and metastasis
    • Jin W., Kim G.M., Kim M.S., Lim M.H., Yun C., Jeong J., et al. TrkC plays an essential role in breast tumor growth and metastasis. Carcinogenesis 2010, 31:1939-1947.
    • (2010) Carcinogenesis , vol.31 , pp. 1939-1947
    • Jin, W.1    Kim, G.M.2    Kim, M.S.3    Lim, M.H.4    Yun, C.5    Jeong, J.6
  • 51
    • 20044381123 scopus 로고    scopus 로고
    • A screen of the complete protein kinase gene family identifies diverse patterns of somatic mutations in human breast cancer
    • Stephens P., Edkins S., Davies H., Greenman C., Cox C., Hunter C., et al. A screen of the complete protein kinase gene family identifies diverse patterns of somatic mutations in human breast cancer. Nature Genetics 2005, 37:590-592.
    • (2005) Nature Genetics , vol.37 , pp. 590-592
    • Stephens, P.1    Edkins, S.2    Davies, H.3    Greenman, C.4    Cox, C.5    Hunter, C.6
  • 55
    • 79958274353 scopus 로고    scopus 로고
    • Targeting neurotrophin-3 and its dependence receptor tyrosine kinase receptor C: a new antitumoral strategy
    • Tauszig-Delamasure S., Bouzas-Rodriguez J. Targeting neurotrophin-3 and its dependence receptor tyrosine kinase receptor C: a new antitumoral strategy. Expert Opinion on Therapeutic Targets 2011, 15:847-858.
    • (2011) Expert Opinion on Therapeutic Targets , vol.15 , pp. 847-858
    • Tauszig-Delamasure, S.1    Bouzas-Rodriguez, J.2
  • 57
    • 80755127904 scopus 로고    scopus 로고
    • The microenvironment in breast cancer progression: biology and implications for treatment
    • Place A.E., Jin Huh S., Polyak K. The microenvironment in breast cancer progression: biology and implications for treatment. Breast Cancer Research 2011, 13:227.
    • (2011) Breast Cancer Research , vol.13 , pp. 227
    • Place, A.E.1    Jin Huh, S.2    Polyak, K.3
  • 58
    • 79956328903 scopus 로고    scopus 로고
    • Molecular mechanisms and clinical applications of angiogenesis
    • Carmeliet P., Jain R.K. Molecular mechanisms and clinical applications of angiogenesis. Nature 2011, 473:298-307.
    • (2011) Nature , vol.473 , pp. 298-307
    • Carmeliet, P.1    Jain, R.K.2
  • 59
    • 80053401068 scopus 로고    scopus 로고
    • Breast cancer stem cells, cytokine networks, and the tumor microenvironment
    • Korkaya H., Liu S., Wicha M.S. Breast cancer stem cells, cytokine networks, and the tumor microenvironment. Journal of Clinical Investigation 2011, 121:3804-3809.
    • (2011) Journal of Clinical Investigation , vol.121 , pp. 3804-3809
    • Korkaya, H.1    Liu, S.2    Wicha, M.S.3
  • 60
    • 74849085724 scopus 로고    scopus 로고
    • Role of endothelial progenitor cells in breast cancer angiogenesis: from fundamental research to clinical ramifications
    • Le Bourhis X., Romon R., Hondermarck H. Role of endothelial progenitor cells in breast cancer angiogenesis: from fundamental research to clinical ramifications. Breast Cancer Research and Treatment 2010, 120:17-24.
    • (2010) Breast Cancer Research and Treatment , vol.120 , pp. 17-24
    • Le Bourhis, X.1    Romon, R.2    Hondermarck, H.3
  • 62
    • 0036674499 scopus 로고    scopus 로고
    • Nerve growth factor-endothelial cell interaction leads to angiogenesis in vitro and in vivo
    • Cantarella G., Lempereur L., Presta M., Ribatti D., Lombardo G., Lazarovici P., et al. Nerve growth factor-endothelial cell interaction leads to angiogenesis in vitro and in vivo. FASEB Journal 2002, 16:1307-1309.
    • (2002) FASEB Journal , vol.16 , pp. 1307-1309
    • Cantarella, G.1    Lempereur, L.2    Presta, M.3    Ribatti, D.4    Lombardo, G.5    Lazarovici, P.6
  • 63
    • 0037159284 scopus 로고    scopus 로고
    • Nerve growth factor promotes angiogenesis and arteriogenesis in ischemic hindlimbs
    • Emanueli C., Salis M.B., Pinna A., Graiani G., Manni L., Madeddu P. Nerve growth factor promotes angiogenesis and arteriogenesis in ischemic hindlimbs. Circulation 2002, 106:2257-2262.
    • (2002) Circulation , vol.106 , pp. 2257-2262
    • Emanueli, C.1    Salis, M.B.2    Pinna, A.3    Graiani, G.4    Manni, L.5    Madeddu, P.6
  • 64
    • 35648951092 scopus 로고    scopus 로고
    • Nerve growth factor induces endothelial cell invasion and cord formation by promoting matrix metalloproteinase-2 expression through the phosphatidylinositol 3-kinase/Akt signaling pathway and AP-2 transcription factor
    • Park M.J., Kwak H.J., Lee H.C., Yoo D.H., Park I.C., Kim M.S., et al. Nerve growth factor induces endothelial cell invasion and cord formation by promoting matrix metalloproteinase-2 expression through the phosphatidylinositol 3-kinase/Akt signaling pathway and AP-2 transcription factor. Journal of Biological Chemistry 2007, 282:30485-30496.
    • (2007) Journal of Biological Chemistry , vol.282 , pp. 30485-30496
    • Park, M.J.1    Kwak, H.J.2    Lee, H.C.3    Yoo, D.H.4    Park, I.C.5    Kim, M.S.6
  • 66
    • 79955409333 scopus 로고    scopus 로고
    • Luminal and basal-like breast cancer cells show increased migration induced by hypoxia, mediated by an autocrine mechanism
    • Voss M.J., Möller M.F., Powe D.G., Niggemann B., Zänker K.S., Entschladen F. Luminal and basal-like breast cancer cells show increased migration induced by hypoxia, mediated by an autocrine mechanism. BMC Cancer 2011, 11:158.
    • (2011) BMC Cancer , vol.11 , pp. 158
    • Voss, M.J.1    Möller, M.F.2    Powe, D.G.3    Niggemann, B.4    Zänker, K.S.5    Entschladen, F.6
  • 68
    • 77958072761 scopus 로고    scopus 로고
    • The multifaceted world of angiogenesis control
    • Guidolin D. The multifaceted world of angiogenesis control. Expert Opinion on Therapeutic Targets 2010, 14:1135-1138.
    • (2010) Expert Opinion on Therapeutic Targets , vol.14 , pp. 1135-1138
    • Guidolin, D.1
  • 69
    • 34247647524 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor: a newly described mediator of angiogenesis
    • Kermani P., Hempstead B. Brain-derived neurotrophic factor: a newly described mediator of angiogenesis. Trends in Cardiovascular Medicine 2007, 17:140-143.
    • (2007) Trends in Cardiovascular Medicine , vol.17 , pp. 140-143
    • Kermani, P.1    Hempstead, B.2
  • 70
    • 79955990588 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor promotes tumorigenesis via induction of neovascularization: implication in hepatocellular carcinoma
    • Lam C.T., Yang Z.F., Lau C.K., Tam K.H., Fan S.T., Poon R.T. Brain-derived neurotrophic factor promotes tumorigenesis via induction of neovascularization: implication in hepatocellular carcinoma. Clinical Cancer Research 2011, 17:3123-3133.
    • (2011) Clinical Cancer Research , vol.17 , pp. 3123-3133
    • Lam, C.T.1    Yang, Z.F.2    Lau, C.K.3    Tam, K.H.4    Fan, S.T.5    Poon, R.T.6
  • 71
    • 77953485565 scopus 로고    scopus 로고
    • Molecular pathways linking inflammation and cancer
    • Mantovani A. Molecular pathways linking inflammation and cancer. Current Molecular Medicine 2010, 10:369-373.
    • (2010) Current Molecular Medicine , vol.10 , pp. 369-373
    • Mantovani, A.1
  • 74
    • 0037085748 scopus 로고    scopus 로고
    • Human eosinophils produce neurotrophins and secrete nerve growth factor on immunologic stimuli
    • Kobayashi H., Gleich G.J., Butterfield J.H., Kita H. Human eosinophils produce neurotrophins and secrete nerve growth factor on immunologic stimuli. Blood 2002, 99:2214-2220.
    • (2002) Blood , vol.99 , pp. 2214-2220
    • Kobayashi, H.1    Gleich, G.J.2    Butterfield, J.H.3    Kita, H.4
  • 79
    • 0029816609 scopus 로고    scopus 로고
    • Association of macrophage infiltration with angiogenesis and prognosis in invasive breast carcinoma
    • Leek R.D., Lewis C.E., Whitehouse R., Greenall M., Clarke J., Harris A.L. Association of macrophage infiltration with angiogenesis and prognosis in invasive breast carcinoma. Cancer Research 1996, 56:4625-4629.
    • (1996) Cancer Research , vol.56 , pp. 4625-4629
    • Leek, R.D.1    Lewis, C.E.2    Whitehouse, R.3    Greenall, M.4    Clarke, J.5    Harris, A.L.6
  • 80
    • 34347226359 scopus 로고    scopus 로고
    • Tumor-associated macrophages press the angiogenic switch in breast cancer
    • Lin E.Y., Pollard J.W. Tumor-associated macrophages press the angiogenic switch in breast cancer. Cancer Research 2007, 67:5064-5066.
    • (2007) Cancer Research , vol.67 , pp. 5064-5066
    • Lin, E.Y.1    Pollard, J.W.2
  • 81
    • 84873406260 scopus 로고    scopus 로고
    • The role of TRKA signaling in IL-10 production by apoptotic tumor cell-activated macrophages
    • [Epub ahead of print]
    • Ley S., Weigert A., Weichand B., Henke N., Mille-Baker B., Janssen R.A., et al. The role of TRKA signaling in IL-10 production by apoptotic tumor cell-activated macrophages. Oncogene 2012 March 12, [Epub ahead of print].
    • (2012) Oncogene
    • Ley, S.1    Weigert, A.2    Weichand, B.3    Henke, N.4    Mille-Baker, B.5    Janssen, R.A.6
  • 83
    • 68149170070 scopus 로고    scopus 로고
    • Perineural invasion in cancer: a review of the literature
    • Liebig C., Ayala G., Wilks J.A., Berger D.H., Albo D. Perineural invasion in cancer: a review of the literature. Cancer 2009, 115:3379-3391.
    • (2009) Cancer , vol.115 , pp. 3379-3391
    • Liebig, C.1    Ayala, G.2    Wilks, J.A.3    Berger, D.H.4    Albo, D.5
  • 84
    • 77649185062 scopus 로고    scopus 로고
    • Molecular mechanisms of perineural invasion, a forgotten pathway of dissemination and metastasis
    • Marchesi F., Piemonti L., Mantovani A., Allavena P. Molecular mechanisms of perineural invasion, a forgotten pathway of dissemination and metastasis. Cytokine and Growth Factor Reviews 2010, 21:77-82.
    • (2010) Cytokine and Growth Factor Reviews , vol.21 , pp. 77-82
    • Marchesi, F.1    Piemonti, L.2    Mantovani, A.3    Allavena, P.4
  • 86
    • 76649092933 scopus 로고    scopus 로고
    • Prevalence and significance of perineural invasion in invasive breast carcinoma
    • Karak S.G., Quatrano N., Buckley J., Ricci A. Prevalence and significance of perineural invasion in invasive breast carcinoma. Connecticut Medicine 2010, 74:17-21.
    • (2010) Connecticut Medicine , vol.74 , pp. 17-21
    • Karak, S.G.1    Quatrano, N.2    Buckley, J.3    Ricci, A.4
  • 87
    • 80052495481 scopus 로고    scopus 로고
    • Potential mechanisms for hypoalgesia induced by anti-nerve growth factor immunoglobulin are identified using autoimmune nerve growth factor deprivation
    • Hoffman E.M., Zhang Z., Anderson M.B., Schechter R., Miller K.E. Potential mechanisms for hypoalgesia induced by anti-nerve growth factor immunoglobulin are identified using autoimmune nerve growth factor deprivation. Neuroscience 2011, 193:452-465.
    • (2011) Neuroscience , vol.193 , pp. 452-465
    • Hoffman, E.M.1    Zhang, Z.2    Anderson, M.B.3    Schechter, R.4    Miller, K.E.5
  • 88
    • 79952027445 scopus 로고    scopus 로고
    • Novel roles for slits and netrins: axon guidance cues as anticancer targets?
    • Mehlen P., Delloye-Bourgeois C., Chédotal A. Novel roles for slits and netrins: axon guidance cues as anticancer targets?. Nature Reviews Cancer 2011, 11:188-197.
    • (2011) Nature Reviews Cancer , vol.11 , pp. 188-197
    • Mehlen, P.1    Delloye-Bourgeois, C.2    Chédotal, A.3
  • 89
    • 33748375335 scopus 로고    scopus 로고
    • Neurotrophins: mediators and modulators of pain
    • Pezet S., McMahon S.B. Neurotrophins: mediators and modulators of pain. Annual Review of Neuroscience 2006, 29:507-538.
    • (2006) Annual Review of Neuroscience , vol.29 , pp. 507-538
    • Pezet, S.1    McMahon, S.B.2
  • 91
    • 27144433512 scopus 로고    scopus 로고
    • A blocking antibody to nerve growth factor attenuates skeletal pain induced by prostate tumor cells growing in bone
    • Halvorson K.G., Kubota K., Sevcik M.A., Lindsay T.H., Sotillo J.E., Ghilardi J.R., et al. A blocking antibody to nerve growth factor attenuates skeletal pain induced by prostate tumor cells growing in bone. Cancer Research 2005, 65:9426-9435.
    • (2005) Cancer Research , vol.65 , pp. 9426-9435
    • Halvorson, K.G.1    Kubota, K.2    Sevcik, M.A.3    Lindsay, T.H.4    Sotillo, J.E.5    Ghilardi, J.R.6
  • 93
    • 0031852411 scopus 로고    scopus 로고
    • Mutational analysis of the TrkA gene in prostate cancer
    • George D.J., Suzuki H., Bova G.S., Isaacs J.T. Mutational analysis of the TrkA gene in prostate cancer. Prostate 1998, 36:172-180.
    • (1998) Prostate , vol.36 , pp. 172-180
    • George, D.J.1    Suzuki, H.2    Bova, G.S.3    Isaacs, J.T.4
  • 94
    • 79955509427 scopus 로고    scopus 로고
    • Role and relevance of TrkB mutations and expression in non-small cell lung cancer
    • Harada T., Yatabe Y., Takeshita M., Koga T., Yano T., Wang Y., et al. Role and relevance of TrkB mutations and expression in non-small cell lung cancer. Clinical Cancer Research 2011, 17:2638-2645.
    • (2011) Clinical Cancer Research , vol.17 , pp. 2638-2645
    • Harada, T.1    Yatabe, Y.2    Takeshita, M.3    Koga, T.4    Yano, T.5    Wang, Y.6
  • 95
    • 79951900121 scopus 로고    scopus 로고
    • Functional characterization of human cancer-derived TRKB mutations
    • Geiger T.R., Song J.Y., Rosado A., Peeper D.S. Functional characterization of human cancer-derived TRKB mutations. PLoS One 2011, 6(2):e16871.
    • (2011) PLoS One , vol.6 , Issue.2
    • Geiger, T.R.1    Song, J.Y.2    Rosado, A.3    Peeper, D.S.4
  • 96
    • 80054988003 scopus 로고    scopus 로고
    • Preventive or late administration of anti-NGF therapy attenuates tumor-induced nerve sprouting, neuroma formation, and cancer pain
    • Jimenez-Andrade J.M., Ghilardi J.R., Castañeda-Corral G., Kuskowski M.A., Mantyh P.W. Preventive or late administration of anti-NGF therapy attenuates tumor-induced nerve sprouting, neuroma formation, and cancer pain. Pain 2011, 152:2564-2574.
    • (2011) Pain , vol.152 , pp. 2564-2574
    • Jimenez-Andrade, J.M.1    Ghilardi, J.R.2    Castañeda-Corral, G.3    Kuskowski, M.A.4    Mantyh, P.W.5
  • 97
    • 79960081481 scopus 로고    scopus 로고
    • Fate of novel painkiller mAbs hangs in balance
    • Garber K. Fate of novel painkiller mAbs hangs in balance. Nature Biotechnology 2011, 29:173-174.
    • (2011) Nature Biotechnology , vol.29 , pp. 173-174
    • Garber, K.1
  • 98
    • 67649392442 scopus 로고    scopus 로고
    • Trk kinase inhibitors as new treatments for cancer and pain
    • Wang T., Yu D., Lamb M.L. Trk kinase inhibitors as new treatments for cancer and pain. Expert Opinion on Therapeutic Targets 2009, 19:305-319.
    • (2009) Expert Opinion on Therapeutic Targets , vol.19 , pp. 305-319
    • Wang, T.1    Yu, D.2    Lamb, M.L.3
  • 99
    • 67651148122 scopus 로고    scopus 로고
    • Identification and preclinical characterization of AZ-23, a novel, selective, and orally bioavailable inhibitor of the Trk kinase pathway
    • Thress K., Macintyre T., Wang H., Whitston D., Liu Z.Y., Hoffmann E., et al. Identification and preclinical characterization of AZ-23, a novel, selective, and orally bioavailable inhibitor of the Trk kinase pathway. Molecular Cancer Therapeutics 2009, 8:1818-1827.
    • (2009) Molecular Cancer Therapeutics , vol.8 , pp. 1818-1827
    • Thress, K.1    Macintyre, T.2    Wang, H.3    Whitston, D.4    Liu, Z.Y.5    Hoffmann, E.6
  • 100
    • 79957845538 scopus 로고    scopus 로고
    • Comparison of the specificity of Trk inhibitors in recombinant and neuronal assays
    • Martin K.J., Shpiro N., Traynor R., Elliott M., Arthur J.S. Comparison of the specificity of Trk inhibitors in recombinant and neuronal assays. Neuropharmacology 2011, 61:148-155.
    • (2011) Neuropharmacology , vol.61 , pp. 148-155
    • Martin, K.J.1    Shpiro, N.2    Traynor, R.3    Elliott, M.4    Arthur, J.S.5
  • 101
    • 20844444589 scopus 로고    scopus 로고
    • Phase I trial of orally administered CEP-701, a novel neurotrophin receptor-linked tyrosine kinase inhibitor
    • Marshall J.L., Kindler H., Deeken J., Bhargava P., Vogelzang N.J., Rizvi N., et al. Phase I trial of orally administered CEP-701, a novel neurotrophin receptor-linked tyrosine kinase inhibitor. Investigational New Drugs 2005, 23:31-37.
    • (2005) Investigational New Drugs , vol.23 , pp. 31-37
    • Marshall, J.L.1    Kindler, H.2    Deeken, J.3    Bhargava, P.4    Vogelzang, N.J.5    Rizvi, N.6
  • 103
    • 84862280700 scopus 로고    scopus 로고
    • Design, synthesis, and evaluation of 3,5-disubstituted 7-azaindoles as trk inhibitors with anticancer and antiangiogenic activities
    • Hong S., Kim J., Seo J.H., Jung K.H., Hong S.S., Hong S. Design, synthesis, and evaluation of 3,5-disubstituted 7-azaindoles as trk inhibitors with anticancer and antiangiogenic activities. Journal of Medicinal Chemistry 2012, 55:5337-5349.
    • (2012) Journal of Medicinal Chemistry , vol.55 , pp. 5337-5349
    • Hong, S.1    Kim, J.2    Seo, J.H.3    Jung, K.H.4    Hong, S.S.5    Hong, S.6
  • 104
    • 84863179654 scopus 로고    scopus 로고
    • Discovery of GNF-5837, a selective TRK inhibitor with efficacy in rodent cancer tumor models
    • Albaugh P., Fan Y., Mi Y., Sun F., Adrian F., Li N., et al. Discovery of GNF-5837, a selective TRK inhibitor with efficacy in rodent cancer tumor models. ACS Medicinal Chemistry Letters 2012, 3:140-145.
    • (2012) ACS Medicinal Chemistry Letters , vol.3 , pp. 140-145
    • Albaugh, P.1    Fan, Y.2    Mi, Y.3    Sun, F.4    Adrian, F.5    Li, N.6
  • 105
    • 51549089009 scopus 로고    scopus 로고
    • Development of therapeutic approaches to 'triple negative' phenotype breast cancer
    • Shiu K.K., Tan D.S., Reis-Filho J.S. Development of therapeutic approaches to 'triple negative' phenotype breast cancer. Expert Opinion on Therapeutic Targets 2008, 12:1123-1137.
    • (2008) Expert Opinion on Therapeutic Targets , vol.12 , pp. 1123-1137
    • Shiu, K.K.1    Tan, D.S.2    Reis-Filho, J.S.3


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