Sulindac sulfide induces autophagic death in gastric epithelial cells via Survivin down-regulation: A mechanism of NSAIDs-induced gastric injury

Biochemical Pharmacology

Volumn 81, Issue 11, 2011, Pages 1317-1323

  Chiou, Shiun Kwei ^a   Hoa, Neil ^a   Hodges, Amy ^a  

^a VA LONG BEACH HEALTHCARE SYSTEM   (United States)

Author keywords

Autophagy; Cell death; Gastric mucosal injury; NSAIDs; Sulindac sulfide; Survivin

Indexed keywords

3 METHYLADENINE; APG7 ENZYME; CELL ENZYME; CELL PROTEIN; CHLOROQUINE; MICROTUBULE ASSOCIATED PROTEIN LIGHT CHAIN 3B; NONSTEROID ANTIINFLAMMATORY AGENT; SMALL INTERFERING RNA; SULINDAC SULFIDE; SURVIVIN; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; AUTOPHAGY; CELL ASSAY; CELL DEATH; CELL LEVEL; CELL STRAIN; CELL VACUOLE; CONTROLLED STUDY; DEPLETION; DOWN REGULATION; DRUG MECHANISM; EPITHELIUM CELL; HUMAN; HUMAN CELL; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; STOMACH EPITHELIUM; STOMACH MUCOSA INJURY;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; AUTOPHAGY; BLOTTING, WESTERN; CELL DEATH; CELL LINE; DOWN-REGULATION; FLOW CYTOMETRY; GASTRIC MUCOSA; HUMANS; INHIBITOR OF APOPTOSIS PROTEINS; RATS; RNA, SMALL INTERFERING; SULINDAC;

EID: 79955596210     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2011.03.019     Document Type: Article

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