Src-homology 2 domain-containing tyrosine phosphatase 2 promotes oral cancer invasion and metastasis

BMC Cancer

Volumn 14, Issue 1, 2014, Pages

  Wang, Hsueh Chun ^a,b   Chiang, Wei Fan ^c   Huang, Hsin Hsiu ^d   Shen, Ying Ying ^d   Chiang, Hung Che ^d  

^a CHINA MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^b CHINA MEDICAL UNIVERSITY   (Taiwan)

^c CHI MEI MEDICAL CENTER   (Taiwan)

^d NATIONAL HEALTH RESEARCH INSTITUTES   (Taiwan)

Author keywords

Extracellular signal related kinase; Invasion; Metastasis; Oral cancer; Src homology 2 domain containing tyrosine phosphatase 2

Indexed keywords

GELATINASE A; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; PROTEIN TYROSINE PHOSPHATASE SHP 2; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR SNAIL; TRANSCRIPTION FACTOR TWIST; UVOMORULIN; VIMENTIN; NUCLEAR PROTEIN; SNAIL FAMILY TRANSCRIPTION FACTORS; TRANSCRIPTION FACTOR; TWIST1 PROTEIN, HUMAN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CANCER CELL LINE; CANCER TISSUE; CARCINOGENESIS; CONTROLLED STUDY; DISEASE ASSOCIATION; DOWN REGULATION; EPITHELIAL MESENCHYMAL TRANSITION; GAPDH GENE; GENE DELETION; GENE SILENCING; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; LUNG METASTASIS; MALE; METASTASIS POTENTIAL; MOLECULAR CLONING; MOUSE; MOUTH CANCER; NONHUMAN; ONCOGENE; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; SHP1 GENE; SHP2 GENE; SNAIL GENE; TUMOR INVASION; TWIST1 GENE; UPREGULATION; ANIMAL; CELL MOTION; DISEASE MODEL; DRUG SCREENING; ENZYME ACTIVATION; GENE EXPRESSION REGULATION; GENETICS; LUNG TUMOR; METABOLISM; METASTASIS; MOUTH TUMOR; PATHOLOGY; SECONDARY; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

ANIMALS; CELL LINE, TUMOR; CELL MOVEMENT; DISEASE MODELS, ANIMAL; ENZYME ACTIVATION; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; LUNG NEOPLASMS; MAP KINASE SIGNALING SYSTEM; MICE; MOUTH NEOPLASMS; NEOPLASM INVASIVENESS; NEOPLASM METASTASIS; NUCLEAR PROTEINS; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 11; TRANSCRIPTION FACTORS; TWIST TRANSCRIPTION FACTOR; UP-REGULATION; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84902980458     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/1471-2407-14-442     Document Type: Article

References (40)

1. Alonso A, Sasin J, Bottini N, Friedberg I, Friedberg I, Osterman A, Godzik A, Hunter T, Dixon J, Mustelin T. Protein tyrosine phosphatases in the human genome. Cell 2004, 117(6):699-711. 10.1016/j.cell.2004.05.018, 15186772.
2. Ostman A, Hellberg C, Bohmer FD. Protein-tyrosine phosphatases and cancer. Nat Rev Cancer 2006, 6(4):307-320. 10.1038/nrc1837, 16557282.
3. Bentires-Alj M, Paez JG, David FS, Keilhack H, Halmos B, Naoki K, Maris JM, Richardson A, Bardelli A, Sugarbaker DJ, Richards WG, Du J, Girard L, Minna JD, Loh ML, Fisher DE, Velculescu VE, Vogelstein B, Meyerson M, Sellers WR, Neel BG. Activating mutations of the noonan syndrome-associated SHP2/PTPN11 gene in human solid tumors and adult acute myelogenous leukemia. Cancer Res 2004, 64(24):8816-8820. 10.1158/0008-5472.CAN-04-1923, 15604238.
4. Loh ML, Vattikuti S, Schubbert S, Reynolds MG, Carlson E, Lieuw KH, Cheng JW, Lee CM, Stokoe D, Bonifas JM, Curtiss NP, Gotlib J, Meshinchi S, Le Beau MM, Emanuel PD, Shannon KM. Mutations in PTPN11 implicate the SHP-2 phosphatase in leukemogenesis. Blood 2004, 103(6):2325-2331. 10.1182/blood-2003-09-3287, 14644997.
5. Mohi MG, Williams IR, Dearolf CR, Chan G, Kutok JL, Cohen S, Morgan K, Boulton C, Shigematsu H, Keilhack H, Akashi K, Gilliland DG, Neel BG. Prognostic, therapeutic, and mechanistic implications of a mouse model of leukemia evoked by Shp2 (PTPN11) mutations. Cancer Cell 2005, 7(2):179-191. 10.1016/j.ccr.2005.01.010, 15710330.
6. Tartaglia M, Mehler EL, Goldberg R, Zampino G, Brunner HG, Kremer H, van der Burgt I, Crosby AH, Ion A, Jeffery S, Kalidas K, Patton MA, Kucherlapati RS, Gelb BD. Mutations in PTPN11, encoding the protein tyrosine phosphatase SHP-2, cause Noonan syndrome. Nat Genet 2001, 29(4):465-468. 10.1038/ng772, 11704759.
7. Tartaglia M, Niemeyer CM, Fragale A, Song X, Buechner J, Jung A, Hahlen K, Hasle H, Licht JD, Gelb BD. Somatic mutations in PTPN11 in juvenile myelomonocytic leukemia, myelodysplastic syndromes and acute myeloid leukemia. Nat Genet 2003, 34(2):148-150. 10.1038/ng1156, 12717436.
8. Mohi MG, Neel BG. The role of Shp2 (PTPN11) in cancer. Curr Opin Genet Dev 2007, 17(1):23-30. 10.1016/j.gde.2006.12.011, 17227708.
9. Aceto N, Sausgruber N, Brinkhaus H, Gaidatzis D, Martiny-Baron G, Mazzarol G, Confalonieri S, Quarto M, Hu G, Balwierz PJ, Pachkov M, Elledge SJ, Van Nimwegen E, Stadler MB, Bentires-Alj M. Tyrosine phosphatase SHP2 promotes breast cancer progression and maintains tumor-initiating cells via activation of key transcription factors and a positive feedback signaling loop. Nat Med 2012, 18(4):529-537. 10.1038/nm.2645, 22388088.
10. Grossmann KS, Rosario M, Birchmeier C, Birchmeier W. The tyrosine phosphatase Shp2 in development and cancer. Adv Cancer Res 2010, 106:53-89.
11. Shi ZQ, Yu DH, Park M, Marshall M, Feng GS. Molecular mechanism for the Shp-2 tyrosine phosphatase function in promoting growth factor stimulation of Erk activity. Mol Cell Biol 2000, 20(5):1526-1536. 10.1128/MCB.20.5.1526-1536.2000, 85329, 10669730.
12. Klein CA. Parallel progression of primary tumours and metastases. Nat Rev Cancer 2009, 9(4):302-312. 10.1038/nrc2627, 19308069.
13. Liao CT, Hsueh C, Lee LY, Lin CY, Fan KH, Wang HM, Huang SF, Chen IH, Kang CJ, Ng SH, Tsao CK, Huang YC, Yen TC. Neck dissection field and lymph node density predict prognosis in patients with oral cavity cancer and pathological node metastases treated with adjuvant therapy. Oral Oncol 2012, 48(4):329-336. 10.1016/j.oraloncology.2011.10.017, 22104249.
14. Ferlito A, Rinaldo A, Devaney KO, MacLennan K, Myers JN, Petruzzelli GJ, Shaha AR, Genden EM, Johnson JT, de Carvalho MB, Myers EN. Prognostic significance of microscopic and macroscopic extracapsular spread from metastatic tumor in the cervical lymph nodes. Oral Oncol 2002, 38(8):747-751. 10.1016/S1368-8375(02)00052-0, 12570052.
15. Mamelle G, Pampurik J, Luboinski B, Lancar R, Lusinchi A, Bosq J. Lymph node prognostic factors in head and neck squamous cell carcinomas. Am J Surg 1994, 168(5):494-498. 10.1016/S0002-9610(05)80109-6, 7977983.
16. Ridley A. Molecular switches in metastasis. Nature 2000, 406(6795):466-467. 10.1038/35020170, 10952292.
17. Fidler IJ. The pathogenesis of cancer metastasis: the 'seed and soil' hypothesis revisited. Nat Rev Cancer 2003, 3(6):453-458. 10.1038/nrc1098, 12778135.
18. Vernon AE, LaBonne C. Tumor metastasis: a new twist on epithelial-mesenchymal transitions. Curr Biol 2004, 14(17):R719-721. 10.1016/j.cub.2004.08.048, 15341765.
19. Thiery JP, Acloque H, Huang RY, Nieto MA. Epithelial-mesenchymal transitions in development and disease. Cell 2009, 139(5):871-890. 10.1016/j.cell.2009.11.007, 19945376.
20. Foda HD, Zucker S. Matrix metalloproteinases in cancer invasion, metastasis and angiogenesis. Drug Discov Today 2001, 6(9):478-482. 10.1016/S1359-6446(01)01752-4, 11344033.
21. Charafe-Jauffret E, Tarpin C, Bardou VJ, Bertucci F, Ginestier C, Braud AC, Puig B, Geneix J, Hassoun J, Birnbaum D, Jacquemier J, Viens P. Immunophenotypic analysis of inflammatory breast cancers: identification of an'inflammatory signature'. J Pathol 2004, 202(3):265-273. 10.1002/path.1515, 14991891.
22. Wang HC, Chiang WF, Huang HH, Huang SK, Chiang HC. Promoter hypermethylation of the gene encoding heat shock protein B1 in oral squamous carcinoma cells. Oral Surg Oral Med Oral Pathol Oral Radiol 2013, 115(3):376-384. 10.1016/j.oooo.2012.12.011, 23453029.
23. Momose F, Araida T, Negishi A, Ichijo H, Shioda S, Sasaki S. Variant sublines with different metastatic potentials selected in nude mice from human oral squamous cell carcinomas. J Oral Pathol Med 1989, 18(7):391-395. 10.1111/j.1600-0714.1989.tb01570.x, 2585303.
24. Leibowitz MS, Srivastava RM, Andrade Filho PA, Egloff AM, Wang L, Seethala RR, Ferrone S, Ferris RL. SHP2 is overexpressed and inhibits pSTAT1-mediated APM component expression, T-cell attracting chemokine secretion, and CTL recognition in head and neck cancer cells. Clin Cancer Res 2013, 19(4):798-808. 10.1158/1078-0432.CCR-12-1517, 3578140, 23363816.
25. Wang HC, Huang YS, Ho CC, Jeng JC, Shih HM. SUMO modification modulates the activity of calpain-2. Biochem Biophys Res Commun 2009, 384(4):444-449. 10.1016/j.bbrc.2009.04.152, 19422794.
26. Wang HC, Wu DH, Chang YC, Li YJ, Wang CJ. Solanum nigrum Linn. water extract inhibits metastasis in mouse melanoma cells in vitro and in vivo. J Agric Food Chem 2010, 58(22):11913-11923. 10.1021/jf1022065, 21028816.
27. Le TL, Yap AS, Stow JL. Recycling of E-cadherin: a potential mechanism for regulating cadherin dynamics. J Cell Biol 1999, 146(1):219-232. 10.1083/jcb.146.1.219, 2199726, 10402472.
28. Larson SD, Jackson LN, Chen LA, Rychahou PG, Evers BM. Effectiveness of siRNA uptake in target tissues by various delivery methods. Surgery 2007, 142(2):262-269. 10.1016/j.surg.2007.03.011, 2427156, 17689694.
29. Wilcox DM, Yang R, Morgan SJ, Nguyen PT, Voorbach MJ, Jung PM, Haasch DL, Lin E, Bush EN, Opgenorth TJ, Jacobson PB, Collins CA, Rondinone CM, Surowy T, Landschulz KT. Delivery of RNAi reagents in murine models of obesity and diabetes. J RNAi Gene Silencing 2006, 3(1):225-236. 2737213, 19771218.
30. Zender L, Hutker S, Liedtke C, Tillmann HL, Zender S, Mundt B, Waltemathe M, Gosling T, Flemming P, Malek NP, Trautwein C, Manns MP, Kuhnel F, Kubicka S. Caspase 8 small interfering RNA prevents acute liver failure in mice. Proc Natl Acad Sci U S A 2003, 100(13):7797-7802. 10.1073/pnas.1330920100, 164667, 12810955.
31. Tsai NP, Lin YL, Tsui YC, Wei LN. Dual action of epidermal growth factor: extracellular signal-stimulated nuclear-cytoplasmic export and coordinated translation of selected messenger RNA. J Cell Biol 2010, 188(3):325-333. 10.1083/jcb.200910083, 2819679, 20142421.
32. Chan G, Kalaitzidis D, Neel BG. The tyrosine phosphatase Shp2 (PTPN11) in cancer. Cancer Metastasis Rev 2008, 27(2):179-192. 10.1007/s10555-008-9126-y, 18286234.
33. Bentires-Alj M, Gil SG, Chan R, Wang ZC, Wang Y, Imanaka N, Harris LN, Richardson A, Neel BG, Gu H. A role for the scaffolding adapter GAB2 in breast cancer. Nat Med 2006, 12(1):114-121. 10.1038/nm1341, 16369543.
34. Bocanegra M, Bergamaschi A, Kim YH, Miller MA, Rajput AB, Kao J, Langerod A, Han W, Noh DY, Jeffrey SS, Huntsman DG, Borresen-Dale AL, Pollack JR. Focal amplification and oncogene dependency of GAB2 in breast cancer. Oncogene 2010, 29(5):774-779. 10.1038/onc.2009.364, 19881546.
35. Kume K, Haraguchi M, Hijioka H, Ishida T, Miyawaki A, Nakamura N, Ozawa M. The transcription factor Snail enhanced the degradation of E-cadherin and desmoglein 2 in oral squamous cell carcinoma cells. Biochem Biophys Res Commun 2013, 430(3):889-894. 10.1016/j.bbrc.2012.12.060, 23261431.
36. Da Silva SD, Alaoui-Jamali MA, Soares FA, Carraro DM, Brentani HP, Hier M, Rogatto SR, Kowalski LP. TWIST1 is a molecular marker for a poor prognosis in oral cancer and represents a potential therapeutic target. Cancer 2014, 120(3):352-362. 10.1002/cncr.28404, 24150986.
37. Babykutty S, PP S, NR J, Kumar MA, Nair MS, Srinivas P, Gopala S. Nimbolide retards tumor cell migration, invasion, and angiogenesis by downregulating MMP-2/9 expression via inhibiting ERK1/2 and reducing DNA-binding activity of NF-kappaB in colon cancer cells. Mol Carcinog 2012, 51(6):475-490. 10.1002/mc.20812, 21678498.
38. Cheng YC, Chen LM, Chang MH, Chen WK, Tsai FJ, Tsai CH, Lai TY, Kuo WW, Huang CY, Liu CJ. Lipopolysaccharide upregulates uPA, MMP-2 and MMP-9 via ERK1/2 signaling in H9c2 cardiomyoblast cells. Mol Cell Biochem 2009, 325(1-2):15-23.
39. Li Z, Li C, Du L, Zhou Y, Wu W. Human chorionic gonadotropin beta induces migration and invasion via activating ERK1/2 and MMP-2 in human prostate cancer DU145 cells. PLoS One 2013, 8(2):e54592. 10.1371/journal.pone.0054592, 3570544, 23424616.
40. Li X, Yang Z, Song W, Zhou L, Li Q, Tao K, Zhou J, Wang X, Zheng Z, You N, Dou K, Li H. Overexpression of Bmi-1 contributes to the invasion and metastasis of hepatocellular carcinoma by increasing the expression of matrix metalloproteinase (MMP)2, MMP-9 and vascular endothelial growth factor via the PTEN/PI3K/Akt pathway. Int J Oncol 2013, 43(3):793-802.