-
1
-
-
0042021703
-
Ocular melanoma: A review and the relationship to cutaneous melanoma
-
Hurst EA, Harbour JW, Cornelius LA. Ocular melanoma: a review and the relationship to cutaneous melanoma. Arch Dermatol. 2003;139:1067-1073.
-
(2003)
Arch Dermatol.
, vol.139
, pp. 1067-1073
-
-
Hurst, E.A.1
Harbour, J.W.2
Cornelius, L.A.3
-
2
-
-
59049107421
-
Frequent somatic mutations of GNAQ in uveal melanoma and blue naevi
-
Van Raamsdonk CD, Bezrookove V, Green G, et al. Frequent somatic mutations of GNAQ in uveal melanoma and blue naevi. Nature. 2009;457:599-602.
-
(2009)
Nature.
, vol.457
, pp. 599-602
-
-
van Raamsdonk, C.D.1
Bezrookove, V.2
Green, G.3
-
4
-
-
78649700287
-
Frequent mutation of BAP1 in metastasizing uveal melanomas
-
Harbour JW, Onken MD, Roberson ED, et al. Frequent mutation of BAP1 in metastasizing uveal melanomas. Science. 2010;330:1410-1413.
-
(2010)
Science.
, vol.330
, pp. 1410-1413
-
-
Harbour, J.W.1
Onken, M.D.2
Roberson, E.D.3
-
5
-
-
77957968556
-
PLX4032, a potent inhibitor of the B-Raf V600E oncogene, selectively inhibits V600E-positive melanomas
-
Lee JT, Li L, Brafford PA, et al. PLX4032, a potent inhibitor of the B-Raf V600E oncogene, selectively inhibits V600E-positive melanomas. Pigment Cell Melanoma Res. 2010;23:820-827.
-
(2010)
Pigment Cell Melanoma Res.
, vol.23
, pp. 820-827
-
-
Lee, J.T.1
Li, L.2
Brafford, P.A.3
-
6
-
-
64049119151
-
MicroRNA-34a inhibits uveal melanoma cell proliferation and migration through downregulation of c-Met
-
Yan D, Zhou X, Chen X, et al. MicroRNA-34a inhibits uveal melanoma cell proliferation and migration through downregulation of c-Met. Invest Ophthalmol Vis Sci. 2009;50:1559-1565.
-
(2009)
Invest Ophthalmol Vis Sci.
, vol.50
, pp. 1559-1565
-
-
Yan, D.1
Zhou, X.2
Chen, X.3
-
7
-
-
79955942571
-
Epigenetics, microRNAs, and carcinogenesis: Functional role of microRNA-137 in uveal melanoma
-
Chen X, Wang J, Shen H, et al. Epigenetics, microRNAs, and carcinogenesis: functional role of microRNA-137 in uveal melanoma. Invest Ophthalmol Vis Sci. 2011;52:1193-1199.
-
(2011)
Invest Ophthalmol Vis Sci.
, vol.52
, pp. 1193-1199
-
-
Chen, X.1
Wang, J.2
Shen, H.3
-
8
-
-
0027751663
-
The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14
-
Lee RC, Feinbaum RL, Ambros V. The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell. 1993;75:843-854.
-
(1993)
Cell.
, vol.75
, pp. 843-854
-
-
Lee, R.C.1
Feinbaum, R.L.2
Ambros, V.3
-
9
-
-
0347444723
-
MicroRNAs: Genomics, biogenesis, mechanism, and function
-
Bartel DP. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell. 2004;116:281-297.
-
(2004)
Cell.
, vol.116
, pp. 281-297
-
-
Bartel, D.P.1
-
11
-
-
33847763576
-
Genetic unmasking of an epigenetically silenced microRNA in human cancer cells
-
Lujambio A, Ropero S, Ballestar E, et al. Genetic unmasking of an epigenetically silenced microRNA in human cancer cells. Cancer Res. 2007;67:1424-1429.
-
(2007)
Cancer Res.
, vol.67
, pp. 1424-1429
-
-
Lujambio, A.1
Ropero, S.2
Ballestar, E.3
-
13
-
-
48949116262
-
miR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells
-
Silber J, Lim DA, Petritsch C, et al. miR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells. BMC Med. 2008;6:14.
-
(2008)
BMC Med.
, vol.6
, pp. 14
-
-
Silber, J.1
Lim, D.A.2
Petritsch, C.3
-
14
-
-
66249148694
-
Epigenetic silencing of the tumor suppressor microRNA Hsa-miR-124a regulates CDK6 expression and confers a poor prognosis in acute lymphoblastic leukemia
-
Agirre X, Vilas-Zornoza A, Jimenez-Velasco A, et al. Epigenetic silencing of the tumor suppressor microRNA Hsa-miR-124a regulates CDK6 expression and confers a poor prognosis in acute lymphoblastic leukemia. Cancer Res. 2009;69:4443-4453.
-
(2009)
Cancer Res.
, vol.69
, pp. 4443-4453
-
-
Agirre, X.1
Vilas-Zornoza, A.2
Jimenez-Velasco, A.3
-
15
-
-
84864403076
-
Role of microRNA-182 in posterior uveal melanoma: Regulation of tumor development through MITF, BCL2 and cyclin D2
-
Yan D, Dong XD, Chen X, et al. Role of microRNA-182 in posterior uveal melanoma: regulation of tumor development through MITF, BCL2 and cyclin D2. PLoS One. 2012;7:e40967.
-
(2012)
PLoS One.
, vol.7
-
-
Yan, D.1
Dong, X.D.2
Chen, X.3
-
16
-
-
34548329963
-
MicroRNA (miRNA) transcriptome of mouse retina and identification of a sensory organ-specific miRNA cluster
-
Xu S, Witmer PD, Lumayag S, Kovacs B, Valle D. MicroRNA (miRNA) transcriptome of mouse retina and identification of a sensory organ-specific miRNA cluster. J Biol Chem. 2007;282: 25053-25066.
-
(2007)
J Biol Chem.
, vol.282
, pp. 25053-25066
-
-
Xu, S.1
Witmer, P.D.2
Lumayag, S.3
Kovacs, B.4
Valle, D.5
-
17
-
-
0031046281
-
Melatonin inhibits growth of cultured human uveal melanoma cells
-
Hu DN, Roberts JE. Melatonin inhibits growth of cultured human uveal melanoma cells. Melanoma Res. 1997;7:27-31.
-
(1997)
Melanoma Res.
, vol.7
, pp. 27-31
-
-
Hu, D.N.1
Roberts, J.E.2
-
18
-
-
0025992296
-
Characterization of gangliosides in human uveal melanoma cells
-
Soulieres D, Rousseau A, Deschenes J, Tremblay M, Tardif M, Pelletier G. Characterization of gangliosides in human uveal melanoma cells. Int J Cancer. 1991;49:498-503.
-
(1991)
Int J Cancer.
, vol.49
, pp. 498-503
-
-
Soulieres, D.1
Rousseau, A.2
Deschenes, J.3
Tremblay, M.4
Tardif, M.5
Pelletier, G.6
-
19
-
-
0027197111
-
Studies of human uveal melanocytes in vitro: Isolation, purification and cultivation of human uveal melanocytes
-
Hu DN, McCormick SA, Ritch R, Pelton-Henrion K. Studies of human uveal melanocytes in vitro: isolation, purification and cultivation of human uveal melanocytes. Invest Ophthalmol Vis Sci. 1993;34:2210-2219.
-
(1993)
Invest Ophthalmol Vis Sci.
, vol.34
, pp. 2210-2219
-
-
Hu, D.N.1
McCormick, S.A.2
Ritch, R.3
Pelton-Henrion, K.4
-
20
-
-
0035710746
-
Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T) Method
-
Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T) Method. Methods. 2001;25:402-408.
-
(2001)
Methods.
, vol.25
, pp. 402-408
-
-
Livak, K.J.1
Schmittgen, T.D.2
-
21
-
-
0022492520
-
Growth and metastasis of tumor cells isolated from a human renal cell carcinoma implanted into different organs of nude mice
-
Naito S, von Eschenbach AC, Giavazzi R, Fidler IJ. Growth and metastasis of tumor cells isolated from a human renal cell carcinoma implanted into different organs of nude mice. Cancer Res. 1986;46:4109-4115.
-
(1986)
Cancer Res.
, vol.46
, pp. 4109-4115
-
-
Naito, S.1
von Eschenbach, A.C.2
Giavazzi, R.3
Fidler, I.J.4
-
22
-
-
84855191863
-
The putative tumour suppressor microRNA-124 modulates hepatocellular carcinoma cell aggressiveness by repressing ROCK2 and EZH2
-
Zheng F, Liao YJ, Cai MY, et al. The putative tumour suppressor microRNA-124 modulates hepatocellular carcinoma cell aggressiveness by repressing ROCK2 and EZH2. Gut. 2012;61: 278-289.
-
(2012)
Gut.
, vol.61
, pp. 278-289
-
-
Zheng, F.1
Liao, Y.J.2
Cai, M.Y.3
-
23
-
-
25444520537
-
miR-15 and miR-16 induce apoptosis by targeting BCL2
-
Cimmino A, Calin GA, Fabbri M, et al. miR-15 and miR-16 induce apoptosis by targeting BCL2. Proc Natl Acad Sci U S A. 2005;102:13944-13949.
-
(2005)
Proc Natl Acad Sci U S A.
, vol.102
, pp. 13944-13949
-
-
Cimmino, A.1
Calin, G.A.2
Fabbri, M.3
-
24
-
-
34547212309
-
The MicroRNA miR-124 promotes neuronal differentiation by triggering brainspecific alternative pre-mRNA splicing
-
Makeyev EV, Zhang J, Carrasco MA, Maniatis T. The MicroRNA miR-124 promotes neuronal differentiation by triggering brainspecific alternative pre-mRNA splicing. Mol Cell. 2007;27:435-448.
-
(2007)
Mol Cell.
, vol.27
, pp. 435-448
-
-
Makeyev, E.V.1
Zhang, J.2
Carrasco, M.A.3
Maniatis, T.4
-
25
-
-
33947180884
-
A functional study of miR-124 in the developing neural tube
-
Cao X, Pfaff SL, Gage FH. A functional study of miR-124 in the developing neural tube. Genes Dev. 2007;21:531-536.
-
(2007)
Genes Dev.
, vol.21
, pp. 531-536
-
-
Cao, X.1
Pfaff, S.L.2
Gage, F.H.3
-
26
-
-
34547126004
-
MicroRNA-124a regulates Foxa2 expression and intracellular signaling in pancreatic beta-cell lines
-
Baroukh N, Ravier MA, Loder MK, et al. MicroRNA-124a regulates Foxa2 expression and intracellular signaling in pancreatic beta-cell lines. J Biol Chem. 2007;282:19575-19588.
-
(2007)
J Biol Chem.
, vol.282
, pp. 19575-19588
-
-
Baroukh, N.1
Ravier, M.A.2
Loder, M.K.3
-
27
-
-
80052263198
-
miR-124a is required for hippocampal axogenesis and retinal cone survival through Lhx2 suppression
-
Sanuki R, Onishi A, Koike C, et al. miR-124a is required for hippocampal axogenesis and retinal cone survival through Lhx2 suppression. Nat Neurosci. 2011;14:1125-1134.
-
(2011)
Nat Neurosci.
, vol.14
, pp. 1125-1134
-
-
Sanuki, R.1
Onishi, A.2
Koike, C.3
-
28
-
-
13944282215
-
Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs
-
Lim LP, Lau NC, Garrett-Engele P, et al. Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs. Nature. 2005;433:769-773.
-
(2005)
Nature.
, vol.433
, pp. 769-773
-
-
Lim, L.P.1
Lau, N.C.2
Garrett-Engele, P.3
-
29
-
-
79952987082
-
miR-124a is frequently down-regulated in glioblastoma and is involved in migration and invasion
-
Fowler A, Thomson D, Giles K, et al. miR-124a is frequently down-regulated in glioblastoma and is involved in migration and invasion. Eur J Cancer. 2011;47:953-963.
-
(2011)
Eur J Cancer.
, vol.47
, pp. 953-963
-
-
Fowler, A.1
Thomson, D.2
Giles, K.3
-
30
-
-
43049133807
-
MicroRNA let-7b targets important cell cycle molecules in malignant melanoma cells and interferes with anchorage-independent growth
-
Schultz J, Lorenz P, Gross G, Ibrahim S, Kunz M. MicroRNA let-7b targets important cell cycle molecules in malignant melanoma cells and interferes with anchorage-independent growth. Cell Res. 2008;18:549-557.
-
(2008)
Cell Res.
, vol.18
, pp. 549-557
-
-
Schultz, J.1
Lorenz, P.2
Gross, G.3
Ibrahim, S.4
Kunz, M.5
-
31
-
-
46349109152
-
Regulation of cyclin dependent kinase 6 by microRNA 124 in medulloblastoma
-
Pierson J, Hostager B, Fan R, Vibhakar R. Regulation of cyclin dependent kinase 6 by microRNA 124 in medulloblastoma. J Neurooncol. 2008;90:1-7.
-
(2008)
J Neurooncol.
, vol.90
, pp. 1-7
-
-
Pierson, J.1
Hostager, B.2
Fan, R.3
Vibhakar, R.4
-
32
-
-
79952994992
-
miR-124a as a key regulator of proliferation and MCP-1 secretion in synoviocytes from patients with rheumatoid arthritis
-
Kawano S, Nakamachi Y. miR-124a as a key regulator of proliferation and MCP-1 secretion in synoviocytes from patients with rheumatoid arthritis. Ann Rheum Dis. 2011; 70:i88-i91.
-
(2011)
Ann Rheum Dis.
, vol.70
-
-
Kawano, S.1
Nakamachi, Y.2
-
33
-
-
77950874502
-
Comprehensive evaluation of the role of EZH2 in the growth, invasion, and aggression of a panel of prostate cancer cell lines
-
Karanikolas BD, Figueiredo ML, Wu L. Comprehensive evaluation of the role of EZH2 in the growth, invasion, and aggression of a panel of prostate cancer cell lines. Prostate. 2010;70:675-688.
-
(2010)
Prostate.
, vol.70
, pp. 675-688
-
-
Karanikolas, B.D.1
Figueiredo, M.L.2
Wu, L.3
-
34
-
-
0027229136
-
Functional interactions of the retinoblastoma protein with mammalian D-type cyclins
-
Ewen ME, Sluss HK, Sherr CJ, Matsushime H, Kato J, Livingston DM. Functional interactions of the retinoblastoma protein with mammalian D-type cyclins. Cell. 1993;73:487-497.
-
(1993)
Cell.
, vol.73
, pp. 487-497
-
-
Ewen, M.E.1
Sluss, H.K.2
Sherr, C.J.3
Matsushime, H.4
Kato, J.5
Livingston, D.M.6
-
35
-
-
0033578816
-
Cdk phosphorylation triggers sequential intramolecular interactions that progressively block Rb functions as cells move through G1
-
Harbour JW, Luo RX, Dei Santi A, Postigo AA, Dean DC. Cdk phosphorylation triggers sequential intramolecular interactions that progressively block Rb functions as cells move through G1. Cell. 1999;98:859-869.
-
(1999)
Cell.
, vol.98
, pp. 859-869
-
-
Harbour, J.W.1
Luo, R.X.2
Dei Santi, A.3
Postigo, A.A.4
Dean, D.C.5
-
36
-
-
34447335892
-
Expression of polycomb group protein EZH2 in nevi and melanoma
-
McHugh JB, Fullen DR, Ma L, Kleer CG, Su LD. Expression of polycomb group protein EZH2 in nevi and melanoma. J Cutan Pathol. 2007;34:597-600.
-
(2007)
J Cutan Pathol.
, vol.34
, pp. 597-600
-
-
McHugh, J.B.1
Fullen, D.R.2
Ma, L.3
Kleer, C.G.4
Su, L.D.5
-
37
-
-
33644822360
-
EZH2 expression is associated with high proliferation rate and aggressive tumor subgroups in cutaneous melanoma and cancers of the endometrium, prostate, and breast
-
Bachmann IM, Halvorsen OJ, Collett K, et al. EZH2 expression is associated with high proliferation rate and aggressive tumor subgroups in cutaneous melanoma and cancers of the endometrium, prostate, and breast. J Clin Oncol. 2006;24: 268-273.
-
(2006)
J Clin Oncol.
, vol.24
, pp. 268-273
-
-
Bachmann, I.M.1
Halvorsen, O.J.2
Collett, K.3
|