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Volumn 13, Issue 6, 2014, Pages 1655-1663

ABT-737 promotes the dislocation of ER luminal proteins to the cytosol, including pseudomonas exotoxin

Author keywords

[No Author keywords available]

Indexed keywords

4 [4 (4' CHLORO 2 BIPHENYLYLMETHYL) 1 PIPERAZINYL] N [4 [3 DIMETHYLAMINO 1 (PHENYLTHIOMETHYL)PROPYLAMINO] 3 NITROBENZENESULFONYL]BENZAMIDE; ADENOSINE TRIPHOSPHATE; CASPASE 3; CASPASE 7; CHAPERONE; CYTOCHROME C; IMMUNOTOXIN; PSEUDOMONAS EXOTOXIN; THAPSIGARGIN; ABT-737; ANTINEOPLASTIC AGENT; BIPHENYL DERIVATIVE; EXOTOXIN; NITROPHENOL; PIPERAZINE DERIVATIVE; SULFONAMIDE;

EID: 84902679802     PISSN: 15357163     EISSN: 15388514     Source Type: Journal    
DOI: 10.1158/1535-7163.MCT-13-0998     Document Type: Article
Times cited : (13)

References (35)
  • 1
    • 79957484300 scopus 로고    scopus 로고
    • Enhancing immunotoxin cell-killing activity via combination therapy with ABT-737
    • Fitzgerald DJ, Moskatel E, Ben-Josef G, Traini R, Tendler T, Sharma A, et al. Enhancing immunotoxin cell-killing activity via combination therapy with ABT-737. Leuk Lymphoma 2011;52 Suppl 2:79-81.
    • (2011) Leuk Lymphoma , vol.52 , Issue.SUPPL. 2 , pp. 79-81
    • Fitzgerald, D.J.1    Moskatel, E.2    Ben-Josef, G.3    Traini, R.4    Tendler, T.5    Sharma, A.6
  • 2
    • 81555214408 scopus 로고    scopus 로고
    • A guide to taming a toxin-recombinant immunotoxins constructed from Pseudomonas exotoxin A for the treatment of cancer
    • Weldon JE, Pastan I. A guide to taming a toxin-recombinant immunotoxins constructed from Pseudomonas exotoxin A for the treatment of cancer. FEBS J 2011;278:4683-700.
    • (2011) FEBS J , vol.278 , pp. 4683-4700
    • Weldon, J.E.1    Pastan, I.2
  • 4
    • 0025012987 scopus 로고
    • Pseudomonas exotoxin contains a specific sequence at the carboxyl terminus that is required for cytotoxicity
    • Chaudhary VK, Jinno Y, FitzGerald D, Pastan I. Pseudomonas exotoxin contains a specific sequence at the carboxyl terminus that is required for cytotoxicity. Proc Natl Acad Sci U S A 1990;87:308-12.
    • (1990) Proc Natl Acad Sci U S a , vol.87 , pp. 308-312
    • Chaudhary, V.K.1    Jinno, Y.2    FitzGerald, D.3    Pastan, I.4
  • 5
    • 0028951457 scopus 로고
    • Importance of the glutamate residue of KDEL in increasing the cytotoxicity of Pseudomonas exotoxin derivatives and for increased binding to the KDEL receptor
    • Kreitman RJ, Pastan I. Importance of the glutamate residue of KDEL in increasing the cytotoxicity of Pseudomonas exotoxin derivatives and for increased binding to the KDEL receptor. Biochem J 1995;307: 29-37.
    • (1995) Biochem J , vol.307 , pp. 29-37
    • Kreitman, R.J.1    Pastan, I.2
  • 6
    • 10744220725 scopus 로고    scopus 로고
    • Expansion of EBV latent membrane protein 2a specific cytotoxic T cells for the adoptive immunotherapy of EBV latency type 2 malignancies: Influence of recombinant IL12 and IL15
    • DOI 10.1080/14653240310001262
    • Wagner HJ, Sili U, Gahn B, Vigouroux S, Huls MH, Xie W, et al. Expansion of EBV latent membrane protein 2a specific cytotoxic T cells for the adoptive immunotherapy of EBV latency type 2 malignancies: influence of recombinant IL12 and IL15. Cytotherapy 2003;5:231-40. (Pubitemid 37086767)
    • (2003) Cytotherapy , vol.5 , Issue.3 , pp. 231-240
    • Wagner, H.-J.1    Sili, U.2    Gahn, B.3    Vigouroux, S.4    Huls, M.H.5    Xie, W.6    Vignali, D.7    Brenner, M.K.8    Heslop, H.E.9    Rooney, C.M.10
  • 7
    • 0023796907 scopus 로고
    • Toxoid of Pseudomonas aeruginosa exotoxin A generated by deletion of an active-site residue
    • Lukac M, Pier GB, Collier RJ. Toxoid of Pseudomonas aeruginosa exotoxin A generated by deletion of an active-site residue. Infect Immun 1988;56:3095-8.
    • (1988) Infect Immun , vol.56 , pp. 3095-3098
    • Lukac, M.1    Pier, G.B.2    Collier, R.J.3
  • 8
    • 0025243542 scopus 로고
    • Processing of Pseudomonas exotoxin by a cellular protease results in the generation of a 37,000-Da toxin fragment that is translocated to the cytosol
    • Ogata M, Chaudhary VK, Pastan I, FitzGerald DJ. Processing of Pseudomonas exotoxin by a cellular protease results in the generation of a 37,000-Da toxin fragment that is translocated to the cytosol. J Biol Chem 1990;265:20678-85. (Pubitemid 120014061)
    • (1990) Journal of Biological Chemistry , vol.265 , Issue.33 , pp. 20678-20685
    • Ogata, M.1    Chaudhary, V.K.2    Pastan, I.3    FitzGerald, D.J.4
  • 9
    • 80054037204 scopus 로고    scopus 로고
    • Treatment of hematologic malignancies with immunotoxins and antibody-drug conjugates
    • FitzGerald DJ, Wayne AS, Kreitman RJ, Pastan I. Treatment of hematologic malignancies with immunotoxins and antibody-drug conjugates. Cancer Res 2011;71:6300-9.
    • (2011) Cancer Res , vol.71 , pp. 6300-6309
    • FitzGerald, D.J.1    Wayne, A.S.2    Kreitman, R.J.3    Pastan, I.4
  • 10
    • 3042621639 scopus 로고    scopus 로고
    • Mesothelin: A new target for immunotherapy
    • DOI 10.1158/1078-0432.CCR-03-0801
    • Hassan R, Bera T, Pastan I. Mesothelin: a new target for immunotherapy. Clin Cancer Res 2004;10:3937-42. (Pubitemid 38812466)
    • (2004) Clinical Cancer Research , vol.10 , Issue.12 I , pp. 3937-3942
    • Hassan, R.1    Bera, T.2    Pastan, I.3
  • 11
    • 84861542159 scopus 로고    scopus 로고
    • Phase I trial of anti-CD22 recombinant immunotoxin moxetumomab pasudotox (CAT-8015 or HA22) in patients with hairy cell leukemia
    • Kreitman RJ, Tallman MS, Robak T, Coutre S, Wilson WH, Stetler- Stevenson M, et al. Phase I trial of anti-CD22 recombinant immunotoxin moxetumomab pasudotox (CAT-8015 or HA22) in patients with hairy cell leukemia. J Clin Oncol 2012;30:1822-8.
    • (2012) J Clin Oncol , vol.30 , pp. 1822-1828
    • Kreitman, R.J.1    Tallman, M.S.2    Robak, T.3    Coutre, S.4    Wilson, W.H.5    Stetler-Stevenson, M.6
  • 12
    • 0025788207 scopus 로고
    • Clinical evaluation of intraperitoneal Pseudomonas exotoxin immunoconjugate OVB3-PE in patients with ovarian cancer
    • Pai LH, Bookman MA, Ozols RF, Young RC, Smith JW II, Longo DL, et al. Clinical evaluation of intraperitoneal Pseudomonas exotoxin immunoconjugate OVB3-PE in patients with ovarian cancer. J Clin Oncol 1991;9:2095- 103.
    • (1991) J Clin Oncol , vol.9 , pp. 2095-2103
    • Pai, L.H.1    Bookman, M.A.2    Ozols, R.F.3    Young, R.C.4    Smith II, J.W.5    Longo, D.L.6
  • 14
    • 84871359162 scopus 로고    scopus 로고
    • Combination treatments with ABT-263 and an immunotoxin produce synergistic killing of ABT-263-resistant small cell lung cancer cell lines
    • Mattoo AR, FitzGerald DJ. Combination treatments with ABT-263 and an immunotoxin produce synergistic killing of ABT-263-resistant small cell lung cancer cell lines. Int J Cancer 2013;132:978-87.
    • (2013) Int J Cancer , vol.132 , pp. 978-987
    • Mattoo, A.R.1    FitzGerald, D.J.2
  • 15
    • 80052845094 scopus 로고    scopus 로고
    • Killing of resistant cancer cells with low Bak by a combination of an antimesothelin immunotoxin and a TRAIL Receptor 2 agonist antibody
    • Du X, Xiang L, Mackall C, Pastan I. Killing of resistant cancer cells with low Bak by a combination of an antimesothelin immunotoxin and a TRAIL Receptor 2 agonist antibody. Clin Cancer Res 2011;17:5926-34.
    • (2011) Clin Cancer Res , vol.17 , pp. 5926-5934
    • Du, X.1    Xiang, L.2    Mackall, C.3    Pastan, I.4
  • 16
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan D, Weinberg RA. The hallmarks of cancer. Cell 2000;100: 57-70. (Pubitemid 30046295)
    • (2000) Cell , vol.100 , Issue.1 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 17
    • 37549048249 scopus 로고    scopus 로고
    • The BCL-2 protein family: Opposing activities that mediate cell death
    • Youle RJ, Strasser A. The BCL-2 protein family: opposing activities that mediate cell death. Nat Rev Mol Cell Biol 2008;9:47-59.
    • (2008) Nat Rev Mol Cell Biol , vol.9 , pp. 47-59
    • Youle, R.J.1    Strasser, A.2
  • 18
    • 0142117313 scopus 로고    scopus 로고
    • The Bcl-2 family: Roles in cell survival and oncogenesis
    • DOI 10.1038/sj.onc.1207102
    • Cory S, Huang DC, Adams JM. The Bcl-2 family: roles in cell survival and oncogenesis. Oncogene 2003;22:8590-607. (Pubitemid 38028528)
    • (2003) Oncogene , vol.22 , Issue.53 REV. ISS. 7 , pp. 8590-8607
    • Cory, S.1    Huang, D.C.S.2    Adams, J.M.3
  • 20
    • 77954566627 scopus 로고    scopus 로고
    • ABT-737 overcomes resistance to immuno-toxin- mediated apoptosis and enhances the delivery of pseudomonas exotoxin-based proteins to the cell cytosol
    • Traini R, Ben-Josef G, Pastrana DV, Moskatel E, Sharma AK, Antignani A, et al. ABT-737 overcomes resistance to immuno-toxin- mediated apoptosis and enhances the delivery of pseudomonas exotoxin-based proteins to the cell cytosol. Mol Cancer Ther 2010;9:2007-15.
    • (2010) Mol Cancer Ther , vol.9 , pp. 2007-2015
    • Traini, R.1    Ben-Josef, G.2    Pastrana, D.V.3    Moskatel, E.4    Sharma, A.K.5    Antignani, A.6
  • 21
    • 80052531606 scopus 로고    scopus 로고
    • Synergistic anticancer effects of the 9.2.27PE immunotoxin and ABT-737 in melanoma
    • Risberg K, Fodstad O, Andersson Y. Synergistic anticancer effects of the 9.2.27PE immunotoxin and ABT-737 in melanoma. PLoS ONE 2011;8:e24012.
    • (2011) PLoS ONE , vol.8
    • Risberg, K.1    Fodstad, O.2    Andersson, Y.3
  • 22
    • 0026792807 scopus 로고
    • A method for increasing the yield of properly folded recombinant fusion proteins: Single-chain immunotoxins from renaturation of bacterial inclusion bodies
    • Buchner J, Pastan I, Brinkmann U. A method for increasing the yield of properly folded recombinant fusion proteins: single-chain immunotoxins from renaturation of bacterial inclusion bodies. Anal Biochem 1992;205:263-70.
    • (1992) Anal Biochem , vol.205 , pp. 263-270
    • Buchner, J.1    Pastan, I.2    Brinkmann, U.3
  • 23
    • 44949208425 scopus 로고    scopus 로고
    • Mammalian cell expression of an active site mutant of Pseudomonas exotoxin disrupts LRP1 maturation
    • Pastrana DV, Yun CH, McKee ML, Fitzgerald DJ. Mammalian cell expression of an active site mutant of Pseudomonas exotoxin disrupts LRP1 maturation. J Biomed Sci 2008;15:427-39.
    • (2008) J Biomed Sci , vol.15 , pp. 427-439
    • Pastrana, D.V.1    Yun, C.H.2    McKee, M.L.3    Fitzgerald, D.J.4
  • 24
    • 0026099098 scopus 로고
    • Analysis of Pseudomonas exotoxin activation and conformational changes by using monoclonal antibodies as probes
    • Ogata M, Pastan I, FitzGerald D. Analysis of Pseudomonas exotoxin activation and conformational changes by using monoclonal antibodies as probes. Infect Immun 1991;59:407-14.
    • (1991) Infect Immun , vol.59 , pp. 407-414
    • Ogata, M.1    Pastan, I.2    FitzGerald, D.3
  • 25
    • 78650169392 scopus 로고    scopus 로고
    • Bcl-2 proteins regulate ER membrane permeability to luminal proteins during ER stress-induced apoptosis
    • Wang X, Olberding KE, White C, Li C. Bcl-2 proteins regulate ER membrane permeability to luminal proteins during ER stress-induced apoptosis. Cell Death Differ 2010;18:38-47.
    • (2010) Cell Death Differ , vol.18 , pp. 38-47
    • Wang, X.1    Olberding, K.E.2    White, C.3    Li, C.4
  • 26
    • 6344289534 scopus 로고    scopus 로고
    • Downregulation of the antiapoptotic Mcl-1 protein and apoptosis in MA-11 breast cancer cells induced by an anti-epidermal growth factor receptor-Pseudomonas exotoxin a immunotoxin
    • DOI 10.1002/ijc.20371
    • Andersson Y, Juell S, Fodstad O. Downregulation of the antiapoptotic MCL-1 protein and apoptosis in MA-11 breast cancer cells induced by an anti-epidermal growth factor receptor-Pseudomonas exotoxin a immunotoxin. Int J Cancer 2004;112:475-83. (Pubitemid 39390614)
    • (2004) International Journal of Cancer , vol.112 , Issue.3 , pp. 475-483
    • Andersson, Y.1    Juell, S.2    Fodstad, O.3
  • 28
    • 0033725154 scopus 로고    scopus 로고
    • Export of antigenic peptides from the endoplasmic reticulum intersects with retrograde protein translocation through the Sec61p channel
    • Koopmann JO, Albring J, Huter E, Bulbuc N, Spee P, Neefjes J, et al. Export of antigenic peptides from the endoplasmic reticulum intersects with retrograde protein translocation through the Sec61p channel. Immunity 2000;13:117-27.
    • (2000) Immunity , vol.13 , pp. 117-127
    • Koopmann, J.O.1    Albring, J.2    Huter, E.3    Bulbuc, N.4    Spee, P.5    Neefjes, J.6
  • 29
    • 33750619845 scopus 로고    scopus 로고
    • How do Bax and Bak lead to permeabilization of the outer mitochondrial membrane?
    • DOI 10.1016/j.ceb.2006.10.004, PII S0955067406001578
    • Antignani A, Youle RJ. Howdo Bax and Bak lead to permeabilization of the outer mitochondrial membrane? Curr Opin Cell Biol 2006;18: 685-9. (Pubitemid 44692478)
    • (2006) Current Opinion in Cell Biology , vol.18 , Issue.6 , pp. 685-689
    • Antignani, A.1    Youle, R.J.2
  • 30
    • 34250899722 scopus 로고    scopus 로고
    • Signal integration in the endoplasmic reticulum unfolded protein response
    • DOI 10.1038/nrm2199, PII NRM2199
    • Ron D, Walter P. Signal integration in the endoplasmic reticulum unfolded protein response. Nat Rev Mol Cell Biol 2007;8: 519-29. (Pubitemid 46985379)
    • (2007) Nature Reviews Molecular Cell Biology , vol.8 , Issue.7 , pp. 519-529
    • Ron, D.1    Walter, P.2
  • 31
    • 0033634654 scopus 로고    scopus 로고
    • Regulated translation initiation controls stress-induced gene expression in mammalian cells
    • Harding HP, Novoa I, Zhang Y, Zeng H, Wek R, Schapira M, et al. Regulated translation initiation controls stress-induced gene expression in mammalian cells. Mol Cell 2000;6:1099-108.
    • (2000) Mol Cell , vol.6 , pp. 1099-1108
    • Harding, H.P.1    Novoa, I.2    Zhang, Y.3    Zeng, H.4    Wek, R.5    Schapira, M.6
  • 32
    • 0041703031 scopus 로고    scopus 로고
    • The function of GADD34 is a recovery from a shutoff of protein synthesis induced by ER stress: Elucidation by GADD34-deficient mice
    • Kojima E, Takeuchi A, Haneda M, Yagi A, Hasegawa T, Yamaki K, et al. The function of GADD34 is a recovery from a shutoff of protein synthesis induced by ER stress: elucidation by GADD34-deficient mice. FASEB J 2003;17:1573-5.
    • (2003) FASEB J , vol.17 , pp. 1573-1575
    • Kojima, E.1    Takeuchi, A.2    Haneda, M.3    Yagi, A.4    Hasegawa, T.5    Yamaki, K.6
  • 33
    • 84877578475 scopus 로고    scopus 로고
    • ER-stress-induced transcriptional regulation increases protein synthesis leading to cell death
    • Han J, Back SH, Hur J, Lin YH, Gildersleeve R, Shan J, et al. ER-stress-induced transcriptional regulation increases protein synthesis leading to cell death. Nat Cell Biol 2013;15:481-90.
    • (2013) Nat Cell Biol , vol.15 , pp. 481-490
    • Han, J.1    Back, S.H.2    Hur, J.3    Lin, Y.H.4    Gildersleeve, R.5    Shan, J.6
  • 35
    • 0035144493 scopus 로고    scopus 로고
    • Gadd153 sensitizes cells to endoplasmic reticulum stress by down-regulating Bc12 and perturbing the cellular redox state
    • DOI 10.1128/MCB.21.4.1249-1259.2001
    • McCullough KD, Martindale JL, Klotz LO, Aw TY, Holbrook NJ. Gadd153 sensitizes cells to endoplasmic reticulum stress by down-egulating Bcl2 and perturbing the cellular redox state. Mol Cell Biol 2001;21:1249-59. (Pubitemid 32114973)
    • (2001) Molecular and Cellular Biology , vol.21 , Issue.4 , pp. 1249-1259
    • McCullough, K.D.1    Martindale, J.L.2    Klotz, L.-O.3    Aw, T.-Y.4    Holbrook, N.J.5


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