Accuracy-rate tradeoffs: How do enzymes meet demands of selectivity and catalytic efficiency?

Current Opinion in Chemical Biology

Volumn 21, Issue , 2014, Pages 73-80

  Tawfik, Dan S ^a  

^a WEIZMANN INSTITUTE OF SCIENCE   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

DNA METHYLTRANSFERASE; ENZYME; POLYDEOXYRIBONUCLEOTIDE SYNTHASE; PROTEIN; DNA (CYTOSINE 5) METHYLTRANSFERASE;

ANALYTICAL PARAMETERS; BIOLOGICAL TRAIT; CATALYSIS; COENZYME; CONFORMATIONAL TRANSITION; DNA REPAIR; DNA SEQUENCE; ENZYME ACTIVITY; ENZYME BINDING; ENZYME MECHANISM; ENZYME SPECIFICITY; ENZYME SUBSTRATE; ENZYME SUBSTRATE COMPLEX; ENZYME SYNTHESIS; EVOLUTIONARY ADAPTATION; MOLECULAR EVOLUTION; MUTATION RATE; NONHUMAN; REVIEW; RIBOSOME; STATIC ELECTRICITY; TURNOVER TIME; BIOCATALYSIS; CHEMISTRY; METABOLISM;

BIOCATALYSIS; DNA (CYTOSINE-5-)-METHYLTRANSFERASE; ENZYMES; EVOLUTION, MOLECULAR; RIBOSOMES; SUBSTRATE SPECIFICITY;

EID: 84902670142     PISSN: 13675931     EISSN: 18790402     Source Type: Journal    
DOI: 10.1016/j.cbpa.2014.05.008     Document Type: Review

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