Enzyme-promoted base flipping controls DNA methylation fidelity

Biochemistry

Volumn 52, Issue 10, 2013, Pages 1677-1685

  Matje, Douglas M ^a   Zhou, Hongjun ^a   Smith, Darren A ^b   Neely, Robert K ^c   Dryden, David T F ^b   Jones, Anita C ^b   Dahlquist, Frederick W ^a   Reich, Norbert O ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF EDINBURGH   (United Kingdom)

^c UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

CATALYTIC EFFICIENCIES; CONFORMATIONAL TRANSITIONS; ENZYME-SUBSTRATE COMPLEXES; NON-SPECIFIC BINDING; NUCLEAR MAGNETIC RESONANCE(NMR); PROTEIN-DNA INTERACTIONS; RATE-LIMITING STEPS; SPECTROSCOPIC EVIDENCE;

ALKYLATION; BINDING ENERGY; SUBSTRATES;

ENZYMES;

DNA (CYTOSINE 5) METHYLTRANSFERASE;

ARTICLE; CATALYSIS; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DNA METHYLATION; DNA SEQUENCE; ENZYME SUBSTRATE COMPLEX; FLUORESCENCE; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; PROTEIN DNA INTERACTION; SPECTROSCOPY;

BACTERIAL PROTEINS; BINDING SITES; CATALYTIC DOMAIN; DNA; DNA METHYLATION; DNA-CYTOSINE METHYLASES; KINETICS; MUTAGENESIS, SITE-DIRECTED; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PROTEIN CONFORMATION; SPECTROMETRY, FLUORESCENCE; SUBSTRATE SPECIFICITY;

EID: 84874973544     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi3012912     Document Type: Article

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