Biological activity and molecular docking studies of curcumin-related α,β-unsaturated carbonyl-based synthetic compounds as anticancer agents and mushroom tyrosinase inhibitors

Journal of Agricultural and Food Chemistry

Volumn 62, Issue 24, 2014, Pages 5538-5547

  Bukhari, Syed Nasir Abbas ^a   Jantan, Ibrahim ^a   Unsal Tan, Oya ^b   Sher, Muhammad ^c   Naeem Ul Hassan, M ^c   Qin, Hua Li ^d  

^a UNIVERSITI KEBANGSAAN MALAYSIA   (Malaysia)

^b HACETTEPE UNIVERSITY   (Turkey)

^c UNIVERSITY OF SARGODHA   (Pakistan)

^d WUHAN UNIVERSITY OF TECHNOLOGY   (China)

Author keywords

antibrowning; Curcuma longa; cytotoxicity; melanogenesis; synthesis

Indexed keywords

BIOACTIVITY; CELL CULTURE; CYTOTOXICITY; ENZYMES; MOLECULAR MODELING; SYNTHESIS (CHEMICAL); UNSATURATED COMPOUNDS; CARBONYL COMPOUNDS;

ANTI-CANCER AGENTS; ANTIBROWNING; CURCUMA LONGA; MELANOGENESIS; MOLECULAR MODELING STUDIES; MUSHROOM TYROSINASE; STRUCTURE ACTIVITY RELATIONSHIPS; SYNTHETIC COMPOUNDS; HUMAN CANCER CELLS;

CARBONYL COMPOUNDS; UNSATURATED COMPOUNDS;

BASIDIOMYCOTA; CURCUMA LONGA;

ANTINEOPLASTIC AGENT; CURCUMIN; ENZYME INHIBITOR; MONOPHENOL MONOOXYGENASE;

AGARICALES; ANTAGONISTS AND INHIBITORS; CHEMICAL STRUCTURE; DRUG DEVELOPMENT; DRUG EFFECTS; ENZYMOLOGY; EPITHELIUM CELL; HT 29 CELL LINE; HUMAN; MCF 7 CELL LINE; METABOLISM; MOLECULAR DOCKING; PHYSICAL CHEMISTRY; STRUCTURE ACTIVITY RELATION; TUMOR CELL LINE;

AGARICALES; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CURCUMIN; DRUG DISCOVERY; ENZYME INHIBITORS; EPITHELIAL CELLS; HT29 CELLS; HUMANS; MCF-7 CELLS; MODELS, MOLECULAR; MOLECULAR DOCKING SIMULATION; MONOPHENOL MONOOXYGENASE; PHYSICOCHEMICAL PHENOMENA; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84902668742     PISSN: 00218561     EISSN: 15205118     Source Type: Journal    
DOI: 10.1021/jf501145b     Document Type: Article

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