Synthesis and biological evaluation of curcumin-like diarylpentanoid analogues for anti-inflammatory, antioxidant and anti-tyrosinase activities

European Journal of Medicinal Chemistry

Volumn 44, Issue 8, 2009, Pages 3195-3200

  Lee, Ka Heng ^a   Ab Aziz, Farida Haryani ^a   Syahida, Ahmad ^a   Abas, Faridah ^a   Shaari, Khozirah ^a   Israf, Daud Ahmad ^a   Lajis, Nordin Haji ^a  

^a UNIVERSITY PUTRA MALAYSIA   (Malaysia)

Author keywords

Anti inflammatory; Anti tyrosinase; Antioxidant; Diarylpentanoids; iNOS

Indexed keywords

1,1 DIPHENYL 2 PICRYLHYDRAZYL; 1,5 BIS(2 HYDROXYPHENYL) 1,4 PENTADIEN 3 ONE; 1,5 BIS(2,5 DIMETHOXYPHENYL) 1,4 PENTADIEN 3 ONE; 2,6 BIS(2,5 DIMETHOXYBENZYLIDENE)CYCLOHEXANONE; CURCUMIN; DIARYLPENTANOID; FLAVONOID; GAMMA INTERFERON; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; KOJIC ACID; LIPOPOLYSACCHARIDE; MONOPHENOL MONOOXYGENASE; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; QUERCETIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME ACTIVITY; HUMAN; HUMAN CELL; IC 50; MACROPHAGE; NONHUMAN; STATISTICAL ANALYSIS;

ANIMALS; ANTI-INFLAMMATORY AGENTS; BIPHENYL COMPOUNDS; CELL LINE; CELL SURVIVAL; CURCUMIN; DRUG DESIGN; ETHYLENEDIAMINES; FREE RADICAL SCAVENGERS; HUMANS; INHIBITORY CONCENTRATION 50; MONOPHENOL MONOOXYGENASE; NITRIC OXIDE; PICRATES; SULFANILAMIDES;

EID: 67349109740     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2009.03.020     Document Type: Article

References (24)

1. Aktan F. Life Sci. 75 (2004) 639-653
2. Abramson A.B., Amin A.R., Clancy R.M., and Attur M. Best Pract. Res. Clin. Rheumatol. 15 (2001) 831-845
3. Gao J., Morrison D.C., Parmely T.J., Russell S.W., and Murphy W.J. J. Biol. Chem. 272 (1997) 1226-1230
4. Sarkar D., and Fisher P.B. Cancer Lett. 236 (2006) 13-23
5. M. Valko, D. Leibfritz, J. Moncol, M.T.D. Cronin, M. Mazur, J. Telser, Int. J. Biochem. Cell Biol. 39 (2007) 44-48.
6. Johar D., Roth J.C., Bay G.H., Walker J.N., Kroczak T.J., and Los M. Rocz. Akad. Med. Bialymst. 49 (2004) 31-39
7. Khatib S., Nerya O., Musa R., Shmuel M., Tamir S., and Vaya J. Bioorg. Med. Chem. 13 (2005) 433-441
8. Nerya O., Musa R., Khatib S., Tamir S., and Vaya J. Phytochemistry 65 (2004) 1389-1395
9. Steward W.P., and Gescher A.J. Mol. Nutr. Food Res. 52 (2008) 1005-1009
10. Gupta A.K., Gover M.D., Nouri K., and Taylor S. J. Am. Acad. Dermatol. 55 (2006) 10481065
11. Wei Q.Y., Ma J.P., Cai Y.J., Yang L., and Liu Z.L. J. Ethnopharmacol. 102 (2005) 177-184
12. Chandru H., Sharada A.C., bettadaiah B.K., Ananda Kumar C.S., Rangappa K.S., Sunila, and Jayashree K. Bioorg. Med. Chem. 15 (2007) 7696-7703
13. Adam B.K., Ferstl E.M., Davis M.C., Herold S.M., Kurtkaya S., Camalier R.F., Hollingshead M.G., Kaur G., Sausville E.A., Rickles F.R., Snyder J.P., Liotta D.C., and Shoji M. Bioorg. Med. Chem. 12 (2004) 3871-3883
14. Weber W.M., Hunsaker L.A., Roybal N., Bobrovnikova-Marjon E.V., Abcouwer S.F., Royer R.E., Deck L.M., and Vander Jagt D.L. Bioorg. Med. Chem. 14 (2006) 2450-2461
15. Ko H.H., Tsao L.T., Yu K.L., Liu C.T., Wang J.P., and Lin C.N. Bioorg. Med. Chem. 11 (2003) 105-111
16. Rojas J., Domínguez J.N., Charris J.E., Lobo G., Payá M., and Ferrándiz M.L. Eur. J. Med. Chem. 37 (2002) 699-705
17. Afonso V., Champy R., Mitovic D., Collin P., and Lomri A. Joint Bone Spine 74 (2007) 324-329
18. Molyneux P., and Songklanakarin. J. Sci. Technol. 26 2 (2004) 211-219
19. Srinivasan M., Sudheer A.R., and Menon V.P. J. Clin. Biochem. Nutr. 40 (2007) 92-100
20. Selvam C., Jachak S.M., Thilagavathi R., and Chakraborti A.K. Bioorg. Med. Chem. 15 (2005) 1793-1797
21. Iozumi K., Hoganson G.E., Pennella R., Everett M.A., and Fuller B.B. J. Invest. Dermatol. 100 (1993) 806-811
22. Tagashira M., and Ohtake Y. Planta Med. 64 (1998) 555-558
23. Mirkov S.M., Djordjevic A.N., Andric N.L., Andric S.A., Kostic T.S., Bogdanovic G.M., Vojinovic-Miloradov M.B., and Kovacevic R.Z. Nitric Oxide 11 (2004) 201-207
24. Tsikas D. J. Chromatogr. B 51 (2007) 51-70