In utero exposure to cigarette smoke dysregulates human fetal ovarian developmental signalling

Human Reproduction

Volumn 29, Issue 7, 2014, Pages 1471-1489

  Fowler, Paul A ^a   Childs, Andrew J ^b   Courant, Frédérique ^c   Mackenzie, Alasdair ^a   Rhind, Stewart M ^d   Antignac, Jean Philippe ^c   Le Bizec, Bruno ^c   Filis, Panagiotis ^a   Evans, Fergus ^a   Flannigan, Samantha ^a   Maheshwari, Abha ^a   Bhattacharya, Siladitya ^a   Monteiro, Ana ^e   Anderson, Richard A ^b   O'Shaughnessy, Peter J ^e  

^a UNIVERSITY OF ABERDEEN   (United Kingdom)

^b UNIVERSITY OF EDINBURGH   (United Kingdom)

^c LUNAM UNIVERSITÉ   (France)

^d SCOTTISH CROP RESEARCH INSTITUTE   (United Kingdom)

^e UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

AhR; cigarette; fetal human; ovary; polycyclic aromatic hydrocarbons

Indexed keywords

ACENAPHTHENE; ACTIVIN; ANTHRACENE; AROMATIC HYDROCARBON RECEPTOR; BENZO[A]PYRENE; BENZO[K]FLUORANTHENE; BENZ[A]ANTHRACENE; CHICKEN OVALBUMIN UPSTREAM PROMOTER TRANSCRIPTION FACTOR 1; CHOLESTEROL MONOOXYGENASE (SIDE CHAIN CLEAVING); CHRYSENE; CIGARETTE SMOKE; ESTROGEN; ESTROGEN RECEPTOR BETA; FLUORANTHENE; FLUORENE; HOMEODOMAIN PROTEIN; INHIBIN A; INHIBIN B; NAPHTHALENE; NOBOX OOGENESIS HOMEOBOX PROTEIN; NUCLEAR RECEPTOR NR2E1; NUCLEAR RECEPTOR NR2F1; OCTAMER TRANSCRIPTION FACTOR 4; PERYLENE; PHENANTHRENE; POLYCYCLIC AROMATIC HYDROCARBON; PROTEIN; PROTEIN HARAKIRI; PYRENE; UNCLASSIFIED DRUG; COTININE; LIGAND;

ADULT; ARTICLE; CELL DENSITY; CONTROLLED STUDY; DEVELOPMENTAL GENE; EMBRYO; ENDOCRINE FUNCTION; ESTROGEN SYNTHESIS; FEMALE; FETOTOXICITY; FETUS DEVELOPMENT; FETUS LIVER; GENE EXPRESSION; GENE PRODUCT; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MATERNAL SMOKING; OOCYTE; OVARY DEVELOPMENT; OVARY FOLLICLE; PRENATAL EXPOSURE; PROTEIN LOCALIZATION; REAL TIME POLYMERASE CHAIN REACTION; REGULATORY MECHANISM; SECOND TRIMESTER PREGNANCY; SIGNAL TRANSDUCTION; WESTERN BLOTTING; ADVERSE EFFECTS; BODY MASS; CELL PROLIFERATION; CYTOLOGY; DRUG EFFECTS; EMBRYOLOGY; ENVIRONMENTAL EXPOSURE; GERM CELL; LIVER; METABOLISM; NEWBORN; OVARY; PATHOLOGY; PHENOTYPE; PREGNANCY; SMOKING; TOBACCO;

ADULT; BODY MASS INDEX; CELL PROLIFERATION; COTININE; ESTROGENS; FEMALE; FETAL DEVELOPMENT; GERM CELLS; HUMANS; IMMUNOHISTOCHEMISTRY; INFANT, NEWBORN; LIGANDS; LIVER; MATERNAL EXPOSURE; OOCYTES; OVARIAN FOLLICLE; OVARY; PHENOTYPE; POLYCYCLIC HYDROCARBONS, AROMATIC; PREGNANCY; PREGNANCY TRIMESTER, SECOND; SIGNAL TRANSDUCTION; SMOKING; TOBACCO PRODUCTS;

EID: 84902667367     PISSN: 02681161     EISSN: 14602350     Source Type: Journal    
DOI: 10.1093/humrep/deu117     Document Type: Article

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