Determinants of maternal sex steroids during the first half of pregnancy

Obstetrics and Gynecology

Volumn 118, Issue 5, 2011, Pages 1029-1036

  Toriola, Adetunji T ^{a,b,c,d,e,f,g,h,i}   Vääräsmäki, Marja ^{a,b,c,d,e,f,g,h,i}   Lehtinen, Matti ^{a,b,c,d,e,f,g,h,i}   Zeleniuch Jacquotte, Anne ^{a,b,c,d,e,f,g,h,i}   Lundin, Eva ^{a,b,c,d,e,f,g,h,i}   Rodgers, Kenneth Gary ^{a,b,c,d,e,f,g,h,i}   Lakso, Hans Ake ^{a,b,c,d,e,f,g,h,i}   Chen, Tianhui ^{a,b,c,d,e,f,g,h,i}   Schock, Helena ^{a,b,c,d,e,f,g,h,i}   Hallmans, Goran ^{a,b,c,d,e,f,g,h,i}   Pukkala, Eero ^{a,b,c,d,e,f,g,h,i}   Toniolo, Paolo ^{a,b,c,d,e,f,g,h,i}   Grankvist, Kjell ^{a,b,c,d,e,f,g,h,i}   Surcel, Helja Marja ^{a,b,c,d,e,f,g,h,i}   Lukanova, Annekatrin ^{a,b,c,d,e,f,g,h,i}  

^a GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^b NATIONAL PUBLIC HEALTH INSTITUTE   (Finland)

^c TAMPERE UNIVERSITY OF TECHNOLOGY   (Finland)

^d NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e NEW YORK UNIVERSITY   (United States)

^f UMEÅ UNIVERSITY   (Sweden)

^g UNIVERSITY OF GLASGOW   (United Kingdom)

^h Institute for Statistical and Epidemiological Cancer Research   (Finland)

ⁱ UNIVERSITY OF LAUSANNE   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ANDROSTENEDIONE; ESTRADIOL; HYDROXYPROGESTERONE; PROGESTERONE; SEX HORMONE; TESTOSTERONE;

ADOLESCENT; ADULT; AGE DISTRIBUTION; ANDROSTENEDIONE BLOOD LEVEL; ANTHROPOMETRIC PARAMETERS; ARTICLE; BIRTH WEIGHT; BODY HEIGHT; ESTROGEN BLOOD LEVEL; FEMALE; FETUS; FIRST TRIMESTER PREGNANCY; GESTATIONAL AGE; HUMAN; MALE; MATERNAL AGE; MATERNAL SMOKING; MULTIPARA; NULLIPARA; PRIORITY JOURNAL; PROGESTERONE BLOOD LEVEL; SECOND TRIMESTER PREGNANCY; SEX HORMONE DETERMINATION; TESTOSTERONE BLOOD LEVEL; WEIGHT INDEX;

ADOLESCENT; ADULT; BIRTH WEIGHT; FEMALE; GONADAL STEROID HORMONES; HUMANS; INFANT, NEWBORN; MALE; MATERNAL AGE; MIDDLE AGED; PARITY; PREGNANCY; PREGNANCY TRIMESTER, FIRST; SEX FACTORS; SMOKING; YOUNG ADULT;

EID: 80054927736     PISSN: 00297844     EISSN: None     Source Type: Journal    
DOI: 10.1097/AOG.0b013e3182342b7f     Document Type: Article

References (44)

1. Medina D. Mammary developmental fate and breast cancer risk. Endocr Relat Cancer 2005;1:483-95. (Pubitemid 41482989)
2. Whittemore AS, McGuire V. Ovarian cancer: Epidemiology and molecular endocrinology. In: Henderson BE, Ponder B, Ross RK, editors. Hormones, genes, and cancer. 1st ed. New York (NY): Oxford University Press; 2003. p. 398-412.
3. Shaheen SO, Hines M, Newson RB, Wheeler M, Herrick DR, Strachan DP, et al. Maternal testosterone in pregnancy and atopic outcomes in childhood. Allergy 2007;62:25-32. (Pubitemid 44902731)
4. Knickmeyer RC, Baron-Cohen S. Fetal testosterone and sex differences in typical social development and in autism. J Child Neurol2006;21:825-45.
5. Abbott DH, Barnett DK, Bruns CM, Dumesic DA. Androgen excess fetal programming of female reproduction: a developmental aetiology for polycystic ovary syndrome? Hum Reprod Update 2005;11:357-74. (Pubitemid 40895465)
6. Holl K, Lundin E, Surcel HM, Grankvist K, Koskela P, Dillner J, et al. Endogenous steroid hormone levels in early pregnancy and risk of testicular cancer in the offspring: a nested casereferent study. Int J Cancer 2009 15;124:2923-8.
7. Swerdlow AJ, De Stavola BL, Swanwick MA, Maconochie NE. Risks of breast and testicular cancers in young adult twins in England and Wales: evidence on prenatal and genetic aetiology. Lancet 1997;350:1723-8. (Pubitemid 28036670)
8. Carlsen SM, Jacobsen G, Romundstad P. Maternal testosterone levels during pregnancy are associated with offspring size at birth. Eur J Endocrinol 2006;155:365-70. (Pubitemid 44269454)
9. Newsome CA, Shiell AW, Fall CH, Phillips DI, Shier R, Law CM. Is birth weight related to later glucose and insulin metabolism?-A systematic review. Diabet Med 2003;20: 339-48. (Pubitemid 36605617)
10. Troisi R, Hoover RN, Thadhani R, Hsieh CC, Sluss P, Ballard-Barbash R, et al. Maternal, prenatal and perinatal characteristics and first trimester maternal serum hormone concentrations. Br J Cancer 2008;99:1161-4.
11. Lehtinen M, Koskela P, Ogmundsdottir HM, Bloigu A, Dillner J, Gudnadottir M, et al. Maternal herpesvirus infections and risk of acute lymphoblastic leukemia in the offspring. Am J Epidemiol 2003;158:207-13. (Pubitemid 36944413)
12. Gissler M, Teperi J, Hemminki E, Merilainen J. Data quality after restructuring a national medical registry. Scand J Soc Med 1995;23:75-80.
13. Csapo AI, Pulkkinen M. Indispensability of the human corpus luteum in the maintenance of early pregnancy. Luteectomy evidence. Obstet Gynecol Surv 1978;33:69-81. (Pubitemid 8267883)
14. Jaffe RB. Neuroendocrine-metabolic regulation of pregnancy. In: Yen SSC, Jaffe RB, Barbieri RL, editors. Reproductive endocrinology. Physiology, pathophysiology, and clinical management. Philadelphia (PA): WB Saunders; 1999. p. 751-811.
15. Tulchinsky D, Hobel CJ, Yeager E, Marshall JR. Plasma estrone, estradiol, estriol, progesterone, and 17-hydroxyprogesterone in human pregnancy. I. Normal pregnancy. Am J Obstet Gynecol 1972;112:1095-100.
16. O'Leary P, Boyne P, Flett P, Beilby J, James I. Longitudinal assessment of changes in reproductive hormones during normal pregnancy. Clin Chem 1991;37:667-72. (Pubitemid 21892706)
17. Kerlan V, Nahoul K, Le Martelot MT, Bercovici JP. Longitudinal study of maternal plasma bioavailable testosterone and androstanediol glucuronide levels during pregnancy. Clin Endocrinol (Oxf) 1994;40:263-7. (Pubitemid 24193158)
18. Carlsen SM, Jacobsen G, Bjerve KS. Androgen levels in pregnant women decrease with increasing maternal age. Scand J Clin Lab Invest 2003;63:23-6. (Pubitemid 36461146)
19. Troisi R, Potischman N, Roberts J, Siiteri P, Daftary A, Sims C, et al. Associations of maternal and umbilical cord hormone concentrations with maternal, gestational and neonatal factors (United States). Cancer Causes Control 2003;14:347-55. (Pubitemid 36735104)
20. Lukanova A, Lundin E, Zeleniuch-Jacquotte A, Muti P, Mure A, Rinaldi S, et al. Body mass index, circulating levels of sex-steroid hormones, IGF-I and IGF-binding protein-3: a cross-sectional study in healthy women. Eur J Endocrinol 2004;150:161-71. (Pubitemid 38312809)
21. Panagiotopoulou K, Katsouyanni K, Petridou E, Garas Y, Tzonou A, Trichopoulos D. Maternal age, parity, and pregnancy estrogens. Cancer Causes Control 1990;1:119-24.
22. Xu B, Pekkanen J, Husman T, Keski-Nisula L, Koskela P. Maternal sex hormones in early pregnancy and asthma among offspring: a case-control study. J Allergy Clin Immunol 2003; 112:1101-4. (Pubitemid 37550001)
23. Arslan AA, Zeleniuch-Jacquotte A, Lukanova A, Afanasyeva Y, Katz J, Levitz M, et al. Effects of parity on pregnancy hormonal profiles across ethnic groups with a diverse incidence of breast cancer. Cancer Epidemiol Biomarkers Prev 2006;15:2123-30. (Pubitemid 44877035)
24. Lof M, Hilakivi-Clarke L, Sandin SS, de Assis S, Yu W, Weiderpass E. Dietary fat intake and gestational weight gain in relation to estradiol and progesterone plasma levels during pregnancy: a longitudinal study in Swedish women. BMC Womens Health 2009;30:9:10.
25. Wuu J, Hellerstein S, Lipworth L, Wide L, Xu B, Yu GP, et al. Correlates of pregnancy oestrogen, progesterone and sex hormone-binding globulin in the USA and China. Eur J Cancer Prev 2002;11:283-93. (Pubitemid 34753888)
26. Musey VC, Collins DC, Brogan DR, Santos VR, Musey PI, Martino-Saltzman D, et al. Long term effects of a first pregnancy on the hormonal environment: estrogens and androgens. J Clin Endocrinol Metab 1987;64:111-8. (Pubitemid 17015887)
27. Cochran CJ, Gallicchio L, Miller SR, Zacur H, Flaws JA. Cigarette smoking, androgen levels, and hot flushes in midlife women. Obstet Gynecol 2008;112:1037-44.
28. Manjer J, Johansson R, Lenner P. Smoking as a determinant for plasma levels of testosterone, androstenedione, and DHEAs in postmenopausal women. Eur J Epidemiol 2005;20: 331-7. (Pubitemid 40685006)
29. Kapoor D, Jones TH. Smoking and hormones in health and endocrine disorders. Eur J Endocrinol 2005;152:491-9. (Pubitemid 40575793)
30. Khaw KT, Tazuke S, Barrett-Connor E. Cigarette smoking and levels of adrenal androgens in postmenopausal women. N Engl J Med 1988;318:1705-9.
31. Petridou E, Panagiotopoulou K, Katsouyanni K, Spanos E, Trichopoulos D. Tobacco smoking, pregnancy estrogens, and birth weight. Epidemiology 1990;1:247-50. (Pubitemid 20300461)
32. Key TJ, Pike MC, Baron JA, Moore JW, Wang DY, Thomas BS, Bulbrook RD. Cigarette smoking and steroid hormones in women. J Steroid Biochem Mol Biol 199139(4A):529-34.
33. Baron JA, La Vecchia C, Levi F. The antiestrogenic effect of cigarette smoking in women. Am J Obstet Gynecol 1990;162: 502-14. (Pubitemid 20068531)
34. Michnovicz JJ, Hershcopf RJ, Naganuma H, Bradlow HL, Fishman J. Increased 2-hydroxylation of estradiol as a possible mechanism for the anti-estrogenic effect of cigarette smoking. N Engl J Med 1986;315:1305-9. (Pubitemid 17030406)
35. Glass AR, Klein T. Changes in maternal serum total and free androgen levels in early pregnancy: lack of correlation with fetal sex. Am J Obstet Gynecol 1981;140:656-60. (Pubitemid 11046347)
36. Steier JA, Ulstein M, Myking OL. Human chorionic gonadotropin and testosterone in normal and preeclamptic pregnancies in relation to fetal sex. Obstet Gynecol 2002;100:552-6. (Pubitemid 35246144)
37. Skjö ldebrand Sparre L, Carlström A, von Schoultz B, Carlstro ̈m K. Serum levels of androgens and estrogens and 'steroidsensitive' liver proteins in early human pregnancy: influence on the gender of the offspring. Gynecol Obstet Invest 1995; 40:145-50.
38. Meulenberg PM, Hofman JA. Maternal testosterone and fetal sex. J Steroid Biochem Mol Biol 1991;39:51-4.
39. Gol M, Altunyurt S, Cimrin D, Guclu S, Bagci M, Demir N. Different maternal serum hCG levels in pregnant women with female and male fetuses: does fetal hypophyseal-adrenal-gonadal axis play a role? J Perinat Med 2004;32:342-5. (Pubitemid 39013850)
40. Hercz P, Kazy Z, Siklos P, Ungar L. Quantitative comparison of serum steroid and peptide hormone concentrations in male and female fetuses in the maternal-fetoplacental system during the 28th-40th weeks of pregnancy. Eur J Obstet Gynecol Reprod Biol 1989;30:201-4. (Pubitemid 19062708)
41. Healthy pregnancy: Stages of pregnancy. U.S. Department of Health and Human Services. Available at: http://www. 4women.gov/pregnancy/you-are-pregnant/ stages-of-pregnancy. cfm#second. Retrieved December 10, 2010.
42. Mucci LA, Lagiou P, Tamimi RM, Hsieh CC, Adami HO, Trichopoulos D. Pregnancy estriol, estradiol, progesterone and prolactin in relation to birth weight and other birth size variables (United States). Cancer Causes Control 2003;14: 311-8. (Pubitemid 36735099)
43. Nagata C, Iwasa S, Shiraki M, Shimizu H. Estrogen and alpha-fetoprotein levels in maternal and umbilical cord blood samples in relation to birth weight. Cancer Epidemiol Biomarkers Prev 2006;15:1469-72. (Pubitemid 44299317)
44. Holl K, Lundin E, Kaasila M, Grankvist K, Afanasyeva Y, Hallmans G, et al. Effect of long-term storage on hormone measurements in samples from pregnant women: the experience of the Finnish Maternity Cohort. Acta Oncol 2008;47: 406-12. (Pubitemid 351414927)