Proposed role for COUP-TFII in regulating fetal leydig cell steroidogenesis, perturbation of which leads to masculinization disorders in rodents

PLoS ONE

Volumn 7, Issue 5, 2012, Pages

  van den Driesche, Sander ^a   Walker, Marion ^a   McKinnell, Chris ^a   Scott, Hayley M ^a   Eddie, Sharon L ^a   Mitchell, Rod T ^a   Seckl, Jonathan R ^b   Drake, Amanda J ^b   Smith, Lee B ^a   Anderson, Richard A ^a   Sharpe, Richard M ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

3(OR 17)BETA HYDROXYSTEROID DEHYDROGENASE; CHICKEN OVALBUMIN UPSTREAM PROMOTER TRANSCRIPTION FACTOR 2; CHOLESTEROL MONOOXYGENASE (SIDE CHAIN CLEAVING); CYTOCHROME P450 17; CYTOCHROME P450 17A1; DEXAMETHASONE; DIETHYLSTILBESTROL; PHTHALIC ACID DIBUTYL ESTER; STEROIDOGENIC ACUTE REGULATORY PROTEIN; STEROIDOGENIC FACTOR 1; TESTOSTERONE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BINDING SITE; CELL SIZE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYP11A1 GENE; CYP17A1 GENE; FETUS; HUMAN; HUMAN TISSUE; LEYDIG CELL; MALE; MOLECULAR MECHANICS; NONHUMAN; NUCLEOTIDE SEQUENCE; PATHOGENESIS; PRENATAL DRUG EXPOSURE; PROMOTER REGION; PROTEIN EXPRESSION; RAT; STAR GENE; STEROIDOGENESIS; TESTOSTERONE SYNTHESIS; VIRILIZATION;

ANIMALS; BINDING SITES; CELL NUCLEUS; COUP TRANSCRIPTION FACTOR II; DIBUTYL PHTHALATE; DNA-BINDING PROTEINS; FEMALE; FETUS; LEYDIG CELLS; MALE; MALE UROGENITAL DISEASES; MICE; MICE, INBRED C57BL; PREGNANCY; PREGNANCY COMPLICATIONS; RATS; RATS, WISTAR; RNA, MESSENGER; RODENTIA; STEROIDOGENIC FACTOR 1; TESTOSTERONE;

MUS; RATTUS; RODENTIA;

EID: 84861217489     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0037064     Document Type: Article

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