mTORC1 and JNK coordinate phosphorylation of the p70S6K1 autoinhibitory domain in skeletal muscle following functional overloading

American Journal of Physiology - Endocrinology and Metabolism

Volumn 306, Issue 12, 2014, Pages

  Martin, Tony D ^a   Dennis, Michael D ^a   Gordon, Bradley S ^a   Kimball, Scot R ^a   Jefferson, Leonard S ^a  

^a PENN STATE COLLEGE OF MEDICINE   (United States)

Author keywords

MAPK signaling; Muscle hypertrophy; Tenotomy

Indexed keywords

ANISOMYCIN; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; P70S6K1 KINASE; PHOSPHOTRANSFERASE; SERINE; STRESS ACTIVATED PROTEIN KINASE; THREONINE; UNCLASSIFIED DRUG;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOINHIBITORY DOMAIN; COMPARATIVE STUDY; CONTROLLED STUDY; GASTROCNEMIUS MUSCLE; HEK293 CELL LINE; IN VITRO STUDY; MALE; MOUSE; MUSCLE HYPERTROPHY; NONHUMAN; PLANTARIS MUSCLE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION; RAT; SKELETAL MUSCLE; TENOTOMY; WESTERN BLOTTING;

MAPK SIGNALING; MUSCLE HYPERTROPHY; TENOTOMY;

ANIMALS; CARRIER PROTEINS; CUMULATIVE TRAUMA DISORDERS; DISEASE MODELS, ANIMAL; HEK293 CELLS; HUMANS; INSULIN-LIKE GROWTH FACTOR I; MALE; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASE 8; MULTIPROTEIN COMPLEXES; MUSCLE, SKELETAL; PHOSPHORYLATION; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEIN KINASE INHIBITORS; PROTEIN PROCESSING, POST-TRANSLATIONAL; RATS; RATS, SPRAGUE-DAWLEY; RIBOSOMAL PROTEIN S6 KINASES; SERINE; THREONINE; TOR SERINE-THREONINE KINASES;

EID: 84902657333     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.00064.2014     Document Type: Article

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