Pterostilbene as a potential novel telomerase inhibitor: Molecular docking studies and its in vitro evaluation

Current Pharmaceutical Biotechnology

Volumn 14, Issue 12, 2014, Pages 1027-1035

  Tippani, Radhika ^a   Prakhya, Laxmi Jaya Shankar ^c   Porika, Mahendar ^a   Sirisha, Kalam ^b   Abbagani, Sadanandam ^a   Thammidala, Christopher ^a  

^a KAKATIYA UNIVERSITY   (India)

^b Vaagdevi College of Pharmacy   (India)

^c CMR COLLEGE OF ENGINEERING TECHNOLOGY   (India)

Author keywords

Antimitotic activity; Cell viability; Molecular docking; Pterostilbene; Telomerase activity

Indexed keywords

CURCUMIN; LIGAND; PTEROSTILBENE; TELOMERASE; TELOMERASE INHIBITOR; UNCLASSIFIED DRUG; ANTIMITOTIC AGENT; ANTINEOPLASTIC AGENT; PROTEIN BINDING; STILBENE DERIVATIVE;

ARTICLE; BREAST CANCER; CELL GROWTH; CELL PROLIFERATION; CELL VIABILITY; CHEMICAL BOND; CHEMICAL STRUCTURE; COMPUTER PROGRAM; CONTROLLED STUDY; CRYSTAL STRUCTURE; CYTOTOXICITY; DRUG ABSORPTION; DRUG ACTIVITY; DRUG DISTRIBUTION; DRUG EXCRETION; DRUG METABOLISM; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN CELL; IC 50; LIPOPHILICITY; LUNG CANCER; MITOSIS INHIBITION; MOLECULAR DOCKING; MOLINSPIRATION; MTT ASSAY; POLYMERASE CHAIN REACTION; SPROUTING; TRIBOLIUM CASTANEUM; ANTAGONISTS AND INHIBITORS; CELL SURVIVAL; CHEMISTRY; DOSE RESPONSE; DRUG EFFECTS; FABACEAE; GERMINATION; IC50; MCF 7 CELL LINE;

ANTIMITOTIC AGENTS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; CELL PROLIFERATION; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; FABACEAE; GERMINATION; HUMANS; INHIBITORY CONCENTRATION 50; MCF-7 CELLS; MOLECULAR DOCKING SIMULATION; PROTEIN BINDING; STILBENES; TELOMERASE;

EID: 84902600920     PISSN: 13892010     EISSN: 18734316     Source Type: Journal    
DOI: 10.2174/1389201015666140113112820     Document Type: Article

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