Curcumin inhibits telomerase and induces telomere shortening and apoptosis in brain tumour cells

Journal of Cellular Biochemistry

Volumn 114, Issue 6, 2013, Pages 1257-1270

  Hande, M Prakash ^a,c   Khaw, Aik Kia ^a   Hande, M Pradeepa ^a   Kalthur, Guruprasad ^a,b  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^b KASTURBA MEDICAL COLLEGE   (India)

^c NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

Apoptosis; Cell Cycle Arrest; Curcumin; Glioblastoma And Medulloblastoma; Telomeres And Telomerase

Indexed keywords

BCL2 RELATED PROTEIN A1; CASPASE 3; CASPASE 7; CURCUMIN; CYCLIN DEPENDENT KINASE 2; MESSENGER RNA; PHOSPHATASE; PHOSPHATASE AND TENSIN HOMOLOG; PROTEIN BAX; SURVIVIN; TELOMERASE; TENSIN; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BRAIN TUMOR; CANCER CELL; CANCER THERAPY; CELL CYCLE ARREST; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CYTOPLASM; DNA DAMAGE; DOWN REGULATION; DRUG CYTOTOXICITY; GENE EXPRESSION; GLIOBLASTOMA; GROWTH INHIBITION; HUMAN; HUMAN CELL; MEDULLOBLASTOMA; PRIORITY JOURNAL; PROTEIN EXPRESSION; TELOMERE; TELOMERE SHORTENING; UPREGULATION;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BRAIN NEOPLASMS; CELL LINE, TUMOR; CELL MEMBRANE; CELL PROLIFERATION; CELL SHAPE; CURCUMIN; CYCLIN E; DNA DAMAGE; DOWN-REGULATION; DRUG SCREENING ASSAYS, ANTITUMOR; E2F1 TRANSCRIPTION FACTOR; G2 PHASE CELL CYCLE CHECKPOINTS; GENE EXPRESSION; HUMANS; INHIBITORY CONCENTRATION 50; ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; TELOMERASE; TELOMERE SHORTENING;

CURCUMA LONGA;

EID: 84876278215     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.24466     Document Type: Article

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