Meta-analysis of cognitive deficits in ultra-high risk to psychosis and first-episode psychosis: Do the cognitive deficits progress over, or after, the onset of psychosis?

Schizophrenia Bulletin

Volumn 40, Issue 4, 2014, Pages 744-755

  Bora, Emre ^a   Murray, Robin M ^b  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

cognition; longitudinal; neuropsychology; psychosis; schizophrenia

Indexed keywords

ANTIDEPRESSANT AGENT; CLOZAPINE; FLUPENTIXOL; HALOPERIDOL DECANOATE; NEUROLEPTIC AGENT; OLANZAPINE; PIMOZIDE; QUETIAPINE; RISPERIDONE;

ARTICLE; ATTENTION; COGNITION; COGNITIVE DEFECT; CONTROLLED STUDY; DISEASE COURSE; EFFECT SIZE; EXECUTIVE FUNCTION; FOLLOW UP; HIGH RISK PATIENT; HUMAN; INFORMATION PROCESSING; LEARNING; LONGITUDINAL STUDY; META ANALYSIS (TOPIC); NEGATIVE SYNDROME; NERVE CELL DIFFERENTIATION; OUTCOME ASSESSMENT; POSITIVE SYNDROME; PRIORITY JOURNAL; PRODROMAL SYMPTOM; PSYCHOSIS; QUANTITATIVE ANALYSIS; SCHIZOPHRENIA; STROOP TEST; VERBAL MEMORY; VISUAL MEMORY; WORKING MEMORY; META ANALYSIS; NEUROPSYCHOLOGICAL TEST; PSYCHOLOGY; RISK;

COGNITION DISORDERS; DISEASE PROGRESSION; HUMANS; LONGITUDINAL STUDIES; NEUROPSYCHOLOGICAL TESTS; PRODROMAL SYMPTOMS; PSYCHOTIC DISORDERS; RISK; SCHIZOPHRENIA; SCHIZOPHRENIC PSYCHOLOGY;

EID: 84902588653     PISSN: 05867614     EISSN: 17451701     Source Type: Journal    
DOI: 10.1093/schbul/sbt085     Document Type: Article

References (71)

1. Gold JM, Harvey PD. Cognitive defcits in schizophrenia. Psychiatr Clin North Am. 1993;16:295-312.
2. Heinrichs RW, Zakzanis KK. Neurocognitive defcit in schizophrenia: a quantitative review of the evidence. Neuropsychology. 1998;12:426-445.
3. Bora E, Yücel M, Pantelis C. Cognitive impairment in schizophrenia and affective psychoses: implications for DSM-V criteria and beyond. Schizophr Bull. 2010;36:36-42.
4. Weinberger DR. The pathogenesis of schizophrenia: a neu-rodevelopmental theory. In: Nasrallah RA, Weinberger DR, eds. The Neurology of Schizophrenia. Amsterdam, the Netherlands: Elsevier; 1986: 387-405.
5. Murray RM, Lewis S W. Is schizophrenia a neurodevelop-mental disorder? BMJ (Clin Res Ed). 1987;295:681-682.
6. Zipursky RB, Reilly TJ, Murray RM. The Myth of Schizophrenia as a Progressive Brain Disease. Schizophr Bull. In press.
7. Reichenberg A, Caspi A, Harrington H, et al. Static and dynamic cognitive defcits in childhood preceding adult schizophrenia: a 30-year study. Am J Psychiatry. 2010;167:160-169.
8. Maccabe JH. Population-based cohort studies on premor-bid cognitive function in schizophrenia. Epidemiol Rev. 2008;30:77-83.
9. Woodberry KA, Giuliano AJ, Seidman LJ. Premorbid IQ in schizophrenia: a meta-analytic review. Am J Psychiatry. 2008;165:579-587.
10. Simon AE, Cattapan-Ludewig K, Zmilacher S, et al. Cognitive functioning in the schizophrenia prodrome. Schizophr Bull. 2007;33:761-771.
11. Pantelis C, Wood SJ, Profftt TM, et al. Attentional set-shifting ability in frst-episode and established schizophrenia: relationship to working memory. Schizophr Res. 2009;112:104-113.
12. Harrison PJ. The neuropathology of schizophrenia. A critical review of the data and their interpretation. Brain. 1999;122 (Pt 4):593-624.
13. Meyer U. Developmental neuroinfammation and schizophrenia. Prog Neuropsychopharmacol Biol Psychiatry. 2013;42:20-34.
14. Monji A, Kato TA, Mizoguchi Y, et al. Neuroinfammation in schizophrenia especially focused on the role of microglia. Prog Neuropsychopharmacol Biol Psychiatry. 2013;42:115-121.
15. Howes OD, Fusar-Poli P, Bloomfeld M, Selvaraj S, McGuire P. From the prodrome to chronic schizophrenia: the neurobi-ology underlying psychotic symptoms and cognitive impairments. Curr Pharm Des. 2012;18:459-465.
16. Keshavan MS, Anderson S, Pettegrew J W. Is schizophrenia due to excessive synaptic pruning in the prefrontal cortex? The Feinberg hypothesis revisited. J Psychiatr Res. 1994;28:239-265.
17. Feinberg I. Schizophrenia: caused by a fault in programmed synaptic elimination during adolescence? J Psychiatr Res. 1982;17:319-334.
18. McGlashan TH. A selective review of recent North American long-term followup studies of schizophrenia. Schizophr Bull. 1988;14:515-542.
19. McGlashan TH, Fenton WS. Subtype progression and patho-physiologic deterioration in early schizophrenia. Schizophr Bull. 1993;19:71-84.
20. McGorry PD, Hickie IB, Yung AR, Pantelis C, Jackson HJ. Clinical staging of psychiatric disorders: a heuristic framework for choosing earlier, safer and more effective interventions. Aust N Z J Psychiatry. 2006;40:616-622.
21. Giuliano AJ, Li H, Mesholam-Gately RI, Sorenson SM, Woodberry KA, Seidman LJ. Neurocognition in the psychosis risk syndrome: a quantitative and qualitative review. Curr Pharm Des. 2012;18:399-415.
22. Fusar-Poli P, Deste G, Smieskova R, et al. Cognitive functioning in prodromal psychosis: a meta-analysis. Arch Gen Psychiatry. 2012;69:562-571.
23. Mesholam-Gately RI, Giuliano AJ, Goff KP, Faraone SV, Seidman LJ. Neurocognition in frst-episode schizophrenia: a meta-analytic review. Neuropsychology. 2009;23:315-336.
24. Szöke A, Trandafr A, Dupont ME, Méary A, Schürhoff F, Leboyer M. Longitudinal studies of cognition in schizophrenia: meta-analysis. Br J Psychiatry. 2008;192:248-257.
25. Irani F, Kalkstein S, Moberg EA, Moberg PJ. Neuro-psychological performance in older patients with schizophrenia: a meta-analysis of cross-sectional and longitudinal studies. Schizophr Bull. 2011;37:1318-1326.
26. Hedman AM, van Haren NE, van Baal CG, Kahn RS, Hulshoff Pol HE. IQ change over time in schizophrenia and healthy individuals: a meta-analysis. Schizophr Res. 2013;146:201-208.
27. McIntosh AM, Gow A, Luciano M, et al. Polygenic risk for schizophrenia is associated with cognitive change between childhood and old age. Biol Psychiatry. 2013;73:938-943. doi: 10.1016/j.biopsych.2013.01.011.
28. Bozikas VP, Andreou C. Longitudinal studies of cognition in frst episode psychosis: a systematic review of the literature. Aust N Z J Psychiatry. 2011;45:93-108.
29. Addington J, Barbato M. The role of cognitive functioning in the outcome of those at clinical high risk for developing psychosis. Epidemiol Psychiatr Sci. 2012;21:335-342.
30. Lin A, Reniers RL, Wood SJ. Clinical staging in severe mental disorder: evidence from neurocognition and neuroimaging. Br J Psychiatry Suppl. 2013;54:s11-s17.
31. Napal O, Ojeda N, Elizagárate E, Peña J, Ezcurra J, Gutiérrez M. The course of the schizophrenia and its impact on cognition: a review of literature. Actas Esp Psiquiatr. 2012;40:198-220.
32. Lewandowski KE, Cohen BM, Ongur D. Evolution of neu-ropsychological dysfunction during the course of schizophrenia and bipolar disorder. Psychol Med. 2011;41:225-241.
33. Stroup DF, Berlin JA, Morton SC, et al. Meta-analysis of observational studies in epidemiology: a proposal for reporting. Meta-analysis Of Observational Studies in Epidemiology (MOOSE) group. JAMA. 2000;283:2008-2012.
34. Albus M, Hubmann W, Scherer J, et al. A prospective 2-year follow-up study of neurocognitive functioning in patients with frst-episode schizophrenia. Eur Arch Psychiatry Clin Neurosci. 2002;252:262-267.
35. Nopoulos P, Flashman L, Flaum M, Arndt S, Andreasen N. Stability of cognitive functioning early in the course of schizophrenia. Schizophr Res. 1994;14:29-37.
36. Wood SJ, Brewer WJ, Koutsouradis P, et al. Cognitive decline following psychosis onset: data from the PACE clinic. Br J Psychiatry Suppl. 2007;51:s52-s57.
37. Keefe RS, Perkins DO, Gu H, Zipursky RB, Christensen BK, Lieberman JA. A longitudinal study of neurocognitive function in individuals at-risk for psychosis. Schizophr Res. 2006;88:26-35.
38. Bowie CR, McLaughlin D, Carrión RE, Auther AM, Cornblatt BA. Cognitive changes following antidepressant or antipsychotic treatment in adolescents at clinical risk for psychosis. Schizophr Res. 2012;137:110-117.
39. Becker HE, Nieman DH, Wiltink S, et al. Neurocognitive functioning before and after the frst psychotic episode: does psychosis result in cognitive deterioration? Psychol Med. 2010;40:1599-1606.
40. Jahshan C, Heaton RK, Golshan S, Cadenhead KS. Course of neurocognitive defcits in the prodrome and frst episode of schizophrenia. Neuropsychology. 2010;24:109-120.
41. Niendam TA, Bearden CE, Zinberg J, Johnson JK, O'Brien M, Cannon TD. The course of neurocognition and social functioning in individuals at ultra high risk for psychosis. Schizophr Bull. 2007;33:772-781.
42. Lin A, Wood SJ, Nelson B, et al. Neurocognitive predictors of functional outcome two to 13 years after identi-fcation as ultra-high risk for psychosis. Schizophr Res. 2011;132:1-7.
43. Barbato M, Colijn MA, Keefe RS, et al. The course of cognitive functioning over six months in individuals at clinical high risk for psychosis. Psychiatry Res. 2013;206:195-199.
44. Keefe RS, Seidman LJ, Christensen BK, et al.; HGDH Research Group. Long-term neurocognitive effects of olan-zapine or low-dose haloperidol in frst-episode psychosis. Biol Psychiatry. 2006;59:97-105.
45. Chan KK, Xu JQ, Liu KC, Hui CL, Wong GH, Chen E Y. Executive function in frst-episode schizophrenia: a three-year prospective study of the Hayling Sentence Completion Test. Schizophr Res. 2012;135:62-67.
46. Rund BR, Melle I, Friis S, et al. The course of neurocogni-tive functioning in frst-episode psychosis and its relation to premorbid adjustment, duration of untreated psychosis, and relapse. Schizophr Res. 2007;91:132-140.
47. Peña J, Ojeda N, Segarra R, Eguiluz JI, García J, Gutiérrez M. Executive functioning correctly classifed diagnoses in patients with frst-episode psychosis: evidence from a 2-year longitudinal study. Schizophr Res. 2011;126:77-80.
48. Addington J, Saeedi H, Addington D. The course of cognitive functioning in frst episode psychosis: changes over time and impact on outcome. Schizophr Res. 2005;78:35-43.
49. Rodríguez-Sánchez JM, Pérez-Iglesias R, González-Blanch C, et al. 1-year follow-up study of cognitive function in frst-epi-sode non-affective psychosis. Schizophr Res. 2008;104:165-174.
50. Albus M, Hubmann W, Mohr F, et al. Neurocognitive functioning in patients with frst-episode schizophrenia: results of a prospective 5-year follow-up study. Eur Arch Psychiatry Clin Neurosci. 2006;256:442-451.
51. Hill SK, Schuepbach D, Herbener ES, Keshavan MS, Sweeney JA. Pretreatment and longitudinal studies of neuropsychological defcits in antipsychotic- naïve patients with schizophrenia. Schizophr Res. 2004;68:49-63.
52. Kopala LC, Good KP, Milliken H, et al. Treatment of a frst episode of psychotic illness with quetiapine: an analysis of 2 year outcomes. Schizophr Res. 2006;81:29-39.
53. Townsend LA, Norman RM, Malla AK, Rychlo AD, Ahmed RR. Changes in cognitive functioning following comprehensive treatment for frst episode patients with schizophrenia spectrum disorders. Psychiatry Res. 2002;113:69-81.
54. Gold S, Arndt S, Nopoulos P, O'Leary DS, Andreasen NC. Longitudinal study of cognitive function in frst-episode and recent-onset schizophrenia. Am J Psychiatry. 1999;156:1342-1348.
55. The Scottish Schizophrenia Research Group. The Scottish First Episode Schizophrenia Study V. One-year follow-up. Br J Psychiatry. 1988;152:470-476.
56. Purdon SE, Jones BD, Stip E, et al. Neuropsychological change in early phase schizophrenia during 12 months of treatment with olanzapine, risperidone, or haloperidol. The Canadian Collaborative Group for research in schizophrenia. Arch Gen Psychiatry. 2000;57:249-258.
57. de Mello Ayres A, Scazufca M, Menezes PR, et al. Cognitive functioning in subjects with recent-onset psychosis from a low-middle-income environment: multiple-domain def-cits and longitudinal evaluation. Psychiatry Res. 2010;179: 157-164.
58. Woodberry KA, McFarlane WR, Giuliano AJ, et al. Change in neuropsychological functioning over one year in youth at clinical high risk for psychosis. Schizophr Res. 2013;146:87-94. doi: 10.1016/j.schres.2013.01.017.
59. Bax L, Yu LM, Ikeda N, Tsuruta H, Moons KG. Development and validation of MIX: comprehensive free software for meta-analysis of causal research data. BMC Med Res Methodol. 2006;6:50.
60. Higgins JP, Thompson SG. Quantifying heterogeneity in a meta-analysis. Stat Med. 2002;21:1539-1558.
61. Hoff AL, Svetina C, Shields G, Stewart J, DeLisi LE. Ten year longitudinal study of neuropsychological functioning subsequent to a frst episode of schizophrenia. Schizophr Res. 2005;78:27-34.
62. Basso MR, Bornstein RA, Lang JM. Practice effects on commonly used measures of executive function across twelve months. Clin Neuropsychol. 1999;13:283-292.
63. Basso MR, Lowery N, Ghormley C, Bornstein RA. Practice effects on the Wisconsin Card Sorting Test-64 Card version across 12 months. Clin Neuropsychol. 2001;15:471-478.
64. Vita A, De Peri L, Deste G, Sacchetti E. Progressive loss of cortical gray matter in schizophrenia: a meta-analysis and meta-regression of longitudinal MRI studies. Transl Psychiatry. 2012;2:e190.
65. Olabi B, Ellison-Wright I, McIntosh AM, Wood SJ, Bullmore E, Lawrie SM. Are there progressive brain changes in schizophrenia? A meta-analysis of structural magnetic resonance imaging studies. Biol Psychiatry. 2011;70:88-96.
66. Kempton MJ, Stahl D, Williams SC, DeLisi LE. Progressive lateral ventricular enlargement in schizophrenia: a meta-analysis of longitudinal MRI studies. Schizophr Res. 2010;120:54-62.
67. Pantelis C, Velakoulis D, McGorry PD, et al. Neuroanatomical abnormalities before and after onset of psychosis: a cross-sectional and longitudinal MRI comparison. Lancet. 2003;361:281-288.
68. Ho BC, Andreasen NC, Ziebell S, Pierson R, Magnotta V. Long-term antipsychotic treatment and brain volumes: a longitudinal study of frst-episode schizophrenia. Arch Gen Psychiatry. 2011;68:128-137.
69. Morgan VA, Leonard H, Bourke J, Jablensky A. Intellectual disability co-occurring with schizophrenia and other psychiatric illness: population-based study. Br J Psychiatry. 2008;193:364-372.
70. Russell AJ, Munro JC, Jones PB, Hemsley DR, Murray RM. Schizophrenia and the myth of intellectual decline. Am J Psychiatry. 1997;154:635-639.
71. Maccabe JH, Wicks S, Löfving S, et al. Decline in cognitive performance between ages 13 and 18 years and the risk for psychosis in adulthood: a Swedish Longitudinal Cohort Study in males. JAMA Psychiatry. 2013;70:261-270. doi: 10.1001/2013jamapsychiatry.43