Attentional set-shifting ability in first-episode and established schizophrenia: Relationship to working memory

Schizophrenia Research

Volumn 112, Issue 1-3, 2009, Pages 104-113

  Pantelis, Christos ^a   Wood, Stephen J ^a   Proffitt, Tina M ^a   Testa, Renee ^a   Mahony, Kate ^a   Brewer, Warrick J ^a   Buchanan, Jo Anne ^a   Velakoulis, Dennis ^a   McGorry, Patrick D ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

Attentional set shifting; First episode psychosis; Neurodevelopment; Prefrontal cortex; Schizophrenia; Spatial working memory

Indexed keywords

ADULT; AMNESIA; ARTICLE; ATTENTIONAL SET SHIFTING ABILITY; COGNITION; COGNITIVE DEFECT; CONTROLLED STUDY; DISEASE DURATION; DISEASE SEVERITY; FEMALE; FIRST EPISODE SCHIZOPHRENIA; HUMAN; MAJOR CLINICAL STUDY; MALE; NERVE DEGENERATION; ONSET AGE; PRIORITY JOURNAL; SCHIZOPHRENIA; SPATIAL MEMORY; TASK PERFORMANCE; WORKING MEMORY;

ADOLESCENT; ADULT; ATTENTION; DISCRIMINATION LEARNING; FEMALE; HUMANS; MALE; MEMORY, SHORT-TERM; NEUROPSYCHOLOGICAL TESTS; PSYCHOTIC DISORDERS; REGRESSION ANALYSIS; SCHIZOPHRENIA; SCHIZOPHRENIC PSYCHOLOGY; SPACE PERCEPTION; YOUNG ADULT;

EID: 67349194032     PISSN: 09209964     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.schres.2009.03.039     Document Type: Article

References (66)

1. Badcock J.C., Michiel P.T., and Rock D. Spatial working memory and planning ability: contrasts between schizophrenia and bipolar I disorder. Cortex 41 6 (2005) 753-763
2. Barcelo F. The Madrid card sorting test (MCST): a task switching paradigm to study executive attention with event-related potentials. Brain Res. Brain Res. Protoc. 11 1 (2003) 27-37
3. Barcelo F., Perianez J.A., and Knight R.T. Think differently: a brain orienting response to task novelty. Neuroreport 13 15 (2002) 1887-1892
4. Barch D., and Smith E. The Cognitive Neuroscience of Working Memory: relevance to CNTRICS and schizophrenia. Biol. Psychiatry 64 1 (2008) 11-17
5. Bartok E., Berecz R., Glaub T., and Degrell I. Cognitive functions in prepsychotic patients. Prog. Neuro-psychopharmacol. Biol. Psychiatry 29 4 (2005) 621-625
6. Borgwardt S.J., McGuire P.K., Aston J., Gschwandtner U., Pfluger M.O., Stieglitz R.D., et al. Reductions in frontal, temporal and parietal volume associated with the onset of psychosis. Schizophr. Res. 106 2-3 (2008) 108-114
7. Brewer W.J., Pantelis C., Anderson V., Velakoulis D., Singh B., Copolov D.L., et al. Stability of olfactory identification deficits in neuroleptic-naive patients with first-episode psychosis. Am. J. Psychiatry 158 1 (2001) 107-115
8. De Luca C., Wood S.J., Anderson V., Buchanan J.A., Proffitt T.M., Mahony K., et al. Normative data from the CANTAB. I: development of executive function over the lifespan. J. Clin. Exp. Neuropsychol. 25 2 (2003) 242-254
9. Downes J.J., Roberts A.C., Sahakian B.J., Evenden J.L., Morris R.G., and Robbins T.W. Impaired extra-dimensional shift performance in medicated and unmedicated Parkinson's disease: evidence for a specific attentional dysfunction. Neuropsychologia 27 11-12 (1989) 1329-1343
10. Driesen N., Leung H., Calhoun V., Constable R., Gueorguieva R., Hoffman R., Skudlarski P., Goldmanrakic P., and Krystal J. Impairment of working memory maintenance and response in schizophrenia: functional magnetic resonance imaging evidence. Biol. Psychiatry 64 12 (2008) 1026-1034
11. Elliott R., and Sahakian B.J. The neuropsychology of schizophrenia: relations with clinical and neurobiological dimensions. Psychol. Med. 25 3 (1995) 581-594
12. Elliott R., McKenna P.J., Robbins T.W., and Sahakian B.J. Neuropsychological evidence for frontostriatal dysfunction in schizophrenia. Psychol. Med. 25 3 (1995) 619-630
13. Elliott R., McKenna P.J., Robbins T.W., and Sahakian B.J. Specific neuropsychological deficits in schizophrenic patients with preserved intellectual function. Cogn. Neuropsychiatry 3 (1998) 45-70
14. Fleming K., Goldberg T.E., Gold J.M., and Weinberger D.R. Verbal working memory dysfunction in schizophrenia: use of a Brown-Peterson paradigm. Psychiatry Res. 56 2 (1995) 155-161
15. Gardner W., Mulvey E.P., and Shaw E.C. Regression analyses of counts and rates: Poisson, overdispersed Poisson, and negative binomial models. Psychol. Bull. 118 3 (1995) 392-404
16. Goldberg T.E., Weinberger D.R., Berman K.F., Pliskin N.H., and Podd M.H. Further evidence for dementia of the prefrontal type in schizophrenia? A controlled study of teaching the Wisconsin Card Sorting Test. Arch. Gen. Psychiatry 44 11 (1987) 1008-1014
17. Haenschel C., Bittner R.A., Haertling F., Rotarska-Jagiela A., Maurer K., Singer W., and Linden D.E.J. Contribution of impaired early-stage visual processing to working memory dysfunction in adolescents with schizophrenia: a study with event-related potentials and functional magnetic resonance imaging. Arch. Gen. Psychiatry 64 11 (2007) 1229-1240
18. Hutton S.B., Puri B.K., Duncan L.J., Robbins T.W., Barnes T.R., and Joyce E.M. Executive function in first-episode schizophrenia. Psychol. Med. 28 2 (1998) 463-473
19. Job D.E., Whalley H.C., Johnstone E., and CsLawrie S.M. Grey matter changes over time in high risk subjects developing schizophrenia. Neuroimage 25 4 (2005) 1023-1030
20. Joyce E., Hutton S., Mutsatsa S., Gibbins H., Webb E., Paul S., et al. Executive dysfunction in first-episode schizophrenia and relationship to duration of untreated psychosis: the West London Study. Br. J. Psychiatr. Suppl. 43 (2002) s38-s44
21. Kay S.R., Fiszbein A., and Opler L.A. The positive and negative syndrome scale (PANSS) for schizophrenia. Schizophr. Bull. 13 2 (1987) 261-276
22. Keefe R.S., Seidman L.J., Christensen B.K., Hamer R.M., Sharma T., Sitskoorn M.M., et al. Long-term neurocognitive effects of olanzapine or low-dose haloperidol in first-episode psychosis. Biol. Psychiatry 59 2 (2006) 97-105
23. Keefe R.S., Sweeney J.A., Gu H., Hamer R.M., Perkins D.O., McEvoy J.P., et al. Effects of olanzapine, quetiapine, and risperidone on neurocognitive function in early psychosis: a randomized, double-blind 52-week comparison. Am. J. Psychiatry 164 7 (2007) 1061-1071
24. Kolb B., and Whishaw I.Q. Performance of schizophrenic patients on tests sensitive to left or right frontal, temporal, or parietal function in neurological patients. J. Nerv. Ment. Dis. 171 7 (1983) 435-443
25. Krawiecka M., Goldberg D., and Vaughan M. A standardized psychiatric assessment scale for rating chronic psychotic patients. Acta Psychiatr. Scand. 55 4 (1977) 299-308
26. Lahti A.C., Holcomb H.H., Medoff D.R., Weiler M.A., Tamminga C.A., and Carpenter Jr. W.T. Abnormal patterns of regional cerebral blood flow in schizophrenia with primary negative symptoms during an effortful auditory recognition task. Am. J. Psychiatry 158 11 (2001) 1797-1808
27. Lee J., Folley B.S., Gore J., Park S., and Zak P. Origins of spatial working memory deficits in schizophrenia: an event-related fMRI and near-infrared spectroscopy study. PLoS ONE 3 3 (2008) e1760
28. Lencz T., Smith C.W., McLaughlin D., Auther A., Nakayama E., Hovey L., et al. Generalized and specific neurocognitive deficits in prodromal schizophrenia. Biol. Psychiatry 59 9 (2006) 863-871
29. Li Z.H., Sun X.W., Wang Z.X., Zhang X.C., Zhang D.R., He S., et al. Behavioral and functional MRI study of attention shift in human verbal working memory. Neuroimage 21 1 (2004) 181-191
30. Liddle P.F., and Morris D.L. Schizophrenic syndromes and frontal lobe performance. Br. J. Psychiatry 158 (1991) 340-345
31. Liddle P.F., Friston K.J., Frith C.D., and Frackowiak R.S. Cerebral blood flow and mental processes in schizophrenia. J. R. Soc. Med. 85 4 (1992) 224-227
32. Long J.S. Regression Models for Categorical and Limited Dependent Variables (1997), Sage, Thousand Oaks, CA
33. Mathes B., Wood S.J., Proffitt T.M., Stuart G.W., Buchanan J.A., Velakoulis D., et al. Early processing deficits in object working memory in first-episode schizophreniform psychosis and established schizophrenia. Psychol. Med. 35 7 (2005) 1053-1062
34. McGorry P.D., Copolov D.L., and Singh B.S. The validity of the assessment of psychopathology in the psychoses. Aust. N. Z. J. Psychiatry 23 4 (1989) 469-482
35. Monchi O., Petrides M., Petre V., Worsley K., and Dagher A. Wisconsin Card Sorting revisited: distinct neural circuits participating in different stages of the task identified by event-related functional magnetic resonance imaging. J. Neurosci. 21 19 (2001) 7733-7741
36. Morice R. Cognitive inflexibility and pre-frontal dysfunction in schizophrenia and mania. Br. J. Psychiatry 157 (1990) 50-54
37. Murray G.K., Cheng F., Clark L., Barnett J.H., Blackwell A.D., Fletcher P.C., et al. Reinforcement and reversal learning in first-episode psychosis. Schizophr. Bull. 34 5 (2008) 848-855
38. Nelson H.E. National Adult Reading Test (NART): Test Manual (1982), NFER, Nelson, Windsor, UK
39. Owen A.M., Roberts A.C., Polkey C.E., Sahakian B.J., and Robbins T.W. Extra-dimensional versus intra-dimensional set shifting performance following frontal lobe excisions, temporal lobe excisions or amygdalo-hippocampectomy in man. Neuropsychologia 29 (1991) 993-1006
40. Pantelis C., and Brewer W. Neuropsychological and olfactory dysfunction in schizophrenia: relationship of frontal syndromes to syndromes of schizophrenia. Schizophr. Res. 17 1 (1995) 35-45
41. Pantelis C., Barnes T.R., Nelson H.E., Tanner S., Weatherley L., Owen A.M., et al. Frontal-striatal cognitive deficits in patients with chronic schizophrenia. Brain 120 Pt 10 (1997) 1823-1843
42. Pantelis C., Barber F.Z., Barnes T.R., Nelson H.E., Owen A.M., and Robbins T.W. Comparison of set-shifting ability in patients with chronic schizophrenia and frontal lobe damage. Schizophr. Res. 37 3 (1999) 251-270
43. Pantelis C., Stuart G.W., Nelson H.E., Robbins T.W., and Barnes T.R. Spatial working memory deficits in schizophrenia: relationship with tardive dyskinesia and negative symptoms. Am. J. Psychiatry 158 8 (2001) 1276-1285
44. Pantelis C., Yucel M., Wood S.J., McGorry P.D., and Velakoulis D. Early and late neurodevelopmental disturbances in schizophrenia and their functional consequences. Aust. N. Z. J. Psychiatry 37 4 (2003) 399-406
45. Pantelis C., Velakoulis D., McGorry P.D., Wood S.J., Suckling J., Phillips L.J., et al. Neuroanatomical abnormalities before and after onset of psychosis: a cross-sectional and longitudinal MRI comparison. Lancet 361 9354 (2003) 281-288
46. Pantelis C., Yucel M., Wood S.J., Velakoulis D., Sun D., Berger G., et al. Structural brain imaging evidence for multiple pathological processes at different stages of brain development in schizophrenia. Schizophr. Bull. 31 3 (2005) 672-696
47. Pantelis C., Velakoulis D., Wood S.J., Yucel M., Yung A.R., Phillips L.J., et al. Neuroimaging and emerging psychotic disorders: the Melbourne ultra-high risk studies. Int. Rev. Psychiatry. 19 4 (2007) 371-379
48. Pantelis C., Proffitt T.M., Wood S.J., O'Brien C.L., Henry L.P., Harris M.G., et al. The Melbourne first-episode medium term follow-up study: decline in attentional set-shifting but not spatial working memory after the onset of psychosis. Schizophr. Bull. 33 2 (2007) 572-572
49. Park S., and Holzman P.S. Schizophrenics show spatial working memory deficits. Arch. Gen. Psychiatry 49 12 (1992) 975-982
50. Park S., Holzman P.S., and Goldman-Rakic P.S. Spatial working memory deficits in the relatives of schizophrenic patients. Arch. Gen. Psychiatry 52 10 (1995) 821-828
51. Premkumar P. Neuropsychological function-brain structure relationships and stage of illness: an investigation into chronic and first-episode schizophrenia. Psychiatry Res. Neuroimaging 162 3 (2008) 195-204
52. Reitan R.M., and Wolfson D. A selective and critical review of neuropsychological deficits and the frontal lobes. Neuropsychol. Rev. 4 3 (1994) 161-198
53. Saperstein A.M., Fuller R.L., Avila M.T., Adami H., McMahon R.P., Thaker G.K., et al. Spatial working memory as a cognitive endophenotype of schizophrenia: assessing risk for pathophysiological dysfunction. Schizophr. Bull. 32 3 (2006) 498-506
54. Schonell F. Backwardness in the Basic Subjects (1942), Oliver and Boyd, London
55. Sun D., Stuart G.W., Jenkinson M., Wood S.J., McGorry P.D., Velakoulis D., et al. Brain surface contraction mapped in first-episode schizophrenia: a longitudinal magnetic resonance imaging study. Mol. Psychiatry (2008), (Electronic publication ahead of print)
56. Sun D., Phillips L., Velakoulis D., Yung A., McGorry P.D., Wood S.J., et al. Progressive brain structural changes mapped as psychosis develops in 'at risk' individuals. Schizophr. Res. 108 1-3 (2009) 85-92
57. Testa R., and Pantelis C. The relevance of executive functions to psychiatric disorders. In: Wood S.J., Allen N.B., and Pantelis C. (Eds). Neuropsychological of Mental Disorders (2009), Cambridge University Press, Cambridge, UK
58. Tyson P.J., Laws K.R., Roberts K.H., and Mortimer A.M. Stability of set-shifting and planning abilities in patients with schizophrenia. Psychiatry Res. 129 3 (2004) 229-239
59. Van Haren N., Hulshoff Pol H.E., Schnack H.G., Cahn W., Mandl Collins D.C., Evans A.C., et al. Focal gray matter changes in schizophrenia across the course of the illness: a five-year follow-up study. Neuropsychopharmacology 32 10 (2007) 2057-2066
60. Van Haren N., Hulshoff Pol H.E., Schnack H.G., Cahn W., Brans R., Carati I., et al. Progressive brain volume loss in schizophrenia over the course of the illness: evidence of maturational abnormalities in early adulthood. Biol. Psychiatry 63 1 (2008) 106-113
61. Wechsler D. The Wechsler Adult Intelligence Scale - Revised (1981), The Psychological Corporation, New York
62. Weinberger D.R., Berman K.F., and Zec R.F. Physiologic dysfunction of dorsolateral prefrontal cortex in schizophrenia. I. Regional cerebral blood flow evidence. Arch. Gen. Psychiatry 43 2 (1986) 114-124
63. Wible C.G., Anderson J., Shenton M.E., Kricun A., Hirayasu Y., Tanaka S., et al. Prefrontal cortex, negative symptoms, and schizophrenia: an MRI study. Psychiatry Res. 108 2 (2001) 65-78
64. Wood S., Proffitt T., Mahony K., Smith D.J., Buchanan J.A., Brewer W., et al. Visuospatial memory and learning in first-episode schizophreniform psychosis and established schizophrenia: a functional correlate of hippocampal pathology?. Psychol. Med. 32 3 (2002) 429-438
65. Wood S., Pantelis C., Proffitt T., Phillips L.J., Stuart G.W., Buchanan J.A., et al. Spatial working memory ability is a marker of risk-for-psychosis. Psychol. Med. 33 7 (2003) 1239-1247
66. Wood S., De Luca C., Anderson V., and Pantelis C. Cognitive development in adolescence: cerebral underpinnings, neural trajectories and the impact of aberrations. In: Keshavan M., Kennedy J., and Murray R. (Eds). Neurodevelopment and Schizophrenia (2004), Cambridge University Press, UK 69-88