메뉴 건너뛰기




Volumn 6, Issue 1, 2014, Pages

The impact of Toll-like-receptor-9 on intestinal microbiota composition and extra-intestinal sequelae in experimental Toxoplasma gondii induced ileitis

Author keywords

Acute ileitis; Bacterial translocation; Bifidobacteria; Extra intestinal immune responses; FOXP3; Gut brain axis; Intestinal microbiota composition; Intracerebral inflammation; Pro inflammatory cytokines; Regulatory T cells; Systemic inflammatory response; Th1 type immunopathology; TLR 9; Toxoplasma gondii

Indexed keywords


EID: 84902550044     PISSN: None     EISSN: 17574749     Source Type: Journal    
DOI: 10.1186/1757-4749-6-19     Document Type: Article
Times cited : (42)

References (51)
  • 1
    • 0029841124 scopus 로고    scopus 로고
    • Association of CD4+ T cell-dependent, interferon-gamma-mediated necrosis of the small intestine with genetic susceptibility of mice to peroral infection with Toxoplasma gondii
    • 10.1084/jem.184.2.597 8760813
    • Association of CD4+ T cell-dependent, interferon-gamma-mediated necrosis of the small intestine with genetic susceptibility of mice to peroral infection with Toxoplasma gondii. Liesenfeld O, Kosek J, Remington JS, Suzuki Y, J Exp Med 1996 184 597 607 10.1084/jem.184.2.597 8760813
    • (1996) J Exp Med , vol.184 , pp. 597-607
    • Liesenfeld, O.1    Kosek, J.2    Remington, J.S.3    Suzuki, Y.4
  • 2
    • 79951886883 scopus 로고    scopus 로고
    • Immunology of Toxoplasma gondii
    • 10.1111/j.1600-065X.2010.00992.x 21349099
    • Immunology of Toxoplasma gondii. Munoz M, Liesenfeld O, Heimesaat MM, Immunol Rev 2011 240 269 285 10.1111/j.1600-065X.2010.00992.x 21349099
    • (2011) Immunol Rev , vol.240 , pp. 269-285
    • Munoz, M.1    Liesenfeld, O.2    Heimesaat, M.M.3
  • 3
    • 0031444279 scopus 로고    scopus 로고
    • A dichotomous role for nitric oxide during acute Toxoplasma gondii infection in mice
    • A dichotomous role for nitric oxide during acute Toxoplasma gondii infection in mice. Khan IA, Schwartzman JD, Matsuura T, Kasper LH, Proc Natl Acad Sci U S A 1996 94 13955 13960
    • (1996) Proc Natl Acad Sci U S A , vol.94 , pp. 13955-13960
    • Khan, I.A.1    Schwartzman, J.D.2    Matsuura, T.3    Kasper, L.H.4
  • 4
    • 0033030226 scopus 로고    scopus 로고
    • TNF-alpha, nitric oxide and IFN-gamma are all critical for development of necrosis in the small intestine and early mortality in genetically susceptible mice infected perorally with Toxoplasma gondii
    • 10.1046/j.1365-3024.1999.00237.x 10417671
    • TNF-alpha, nitric oxide and IFN-gamma are all critical for development of necrosis in the small intestine and early mortality in genetically susceptible mice infected perorally with Toxoplasma gondii. Liesenfeld O, Kang H, Park D, Nguyen TA, Parkhe CV, Watanabe H, Abo T, Sher A, Remington JS, Suzuki Y, Parasite Immunol 1999 21 365 376 10.1046/j.1365-3024.1999.00237.x 10417671
    • (1999) Parasite Immunol , vol.21 , pp. 365-376
    • Liesenfeld, O.1    Kang, H.2    Park, D.3    Nguyen, T.A.4    Parkhe, C.V.5    Watanabe, H.6    Abo, T.7    Sher, A.8    Remington, J.S.9    Suzuki, Y.10
  • 5
    • 0037087260 scopus 로고    scopus 로고
    • Lamina propria CD4+ T lymphocytes synergize with murine intestinal epithelial cells to enhance proinflammatory response against an intracellular pathogen
    • 10.4049/jimmunol.168.6.2988 11884471
    • Lamina propria CD4+ T lymphocytes synergize with murine intestinal epithelial cells to enhance proinflammatory response against an intracellular pathogen. Mennechet FJL, Kasper H, Rachinel N, Li W, Vandewalle A, Buzoni-Gatel D, J Immunol 2002 168 2988 2996 10.4049/jimmunol.168.6.2988 11884471
    • (2002) J Immunol , vol.168 , pp. 2988-2996
    • Mennechet, F.J.L.1    Kasper, H.2    Rachinel, N.3    Li, W.4    Vandewalle, A.5    Buzoni-Gatel, D.6
  • 6
    • 9244250314 scopus 로고    scopus 로고
    • Both IL-12 and IL-18 contribute to small intestinal Th1-type immunopathology following oral infection with Toxoplasma gondii, but IL-12 is dominant over IL-18 in parasite control
    • 10.1002/eji.200424993 15368276
    • Both IL-12 and IL-18 contribute to small intestinal Th1-type immunopathology following oral infection with Toxoplasma gondii, but IL-12 is dominant over IL-18 in parasite control. Vossenkamper A, Struck D, Alvarado-Esquivel C, Went T, Takeda K, Akira S, Pfeffer K, Alber G, Lochner M, Forster I, Liesenfeld O, Eur J Immunol 2004 34 3197 3207 10.1002/eji.200424993 15368276
    • (2004) Eur J Immunol , vol.34 , pp. 3197-3207
    • Vossenkamper, A.1    Struck, D.2    Alvarado-Esquivel, C.3    Went, T.4    Takeda, K.5    Akira, S.6    Pfeffer, K.7    Alber, G.8    Lochner, M.9    Forster, I.10    Liesenfeld, O.11
  • 7
    • 33644857137 scopus 로고    scopus 로고
    • Mucosal defences against orally acquired protozoan parasites, emphasis on Toxoplasma gondii infections
    • 10.1111/j.1462-5822.2006.00692.x 16548880
    • Mucosal defences against orally acquired protozoan parasites, emphasis on Toxoplasma gondii infections. Buzoni-Gatel D, Schulthess J, Menard LC, Kasper LH, Cell Microbiol 2006 8 535 544 10.1111/j.1462-5822.2006.00692.x 16548880
    • (2006) Cell Microbiol , vol.8 , pp. 535-544
    • Buzoni-Gatel, D.1    Schulthess, J.2    Menard, L.C.3    Kasper, L.H.4
  • 8
    • 0037083246 scopus 로고    scopus 로고
    • Oral infection of C57BL/6 mice with Toxoplasma gondii: A new model of inflammatory bowel disease?
    • 11865446
    • Oral infection of C57BL/6 mice with Toxoplasma gondii: a new model of inflammatory bowel disease? Liesenfeld O, J Infect Dis 2002 185 Suppl 1 96 S101 11865446
    • (2002) J Infect Dis , vol.185 , Issue.SUPPL. 1
    • Liesenfeld, O.1
  • 11
    • 77949414935 scopus 로고    scopus 로고
    • The induction of colitis and ileitis in mice is associated with marked increases in intestinal concentrations of stimulants of TLRs 2, 4, and 5
    • The induction of colitis and ileitis in mice is associated with marked increases in intestinal concentrations of stimulants of TLRs 2, 4, and 5. Erridge C, Duncan SH, Bereswill S, Heimesaat MM, PLoS One 2011 5 9125
    • (2011) PLoS One , vol.5 , pp. 59125
    • Erridge, C.1    Duncan, S.H.2    Bereswill, S.3    Heimesaat, M.M.4
  • 13
    • 12444341944 scopus 로고    scopus 로고
    • Toll-like receptors in innate immunity
    • 15585605
    • Toll-like receptors in innate immunity. Takeda K, Akira S, Int Immunol 2005 17 1 14 15585605
    • (2005) Int Immunol , vol.17 , pp. 1-14
    • Takeda, K.1    Akira, S.2
  • 14
    • 4644330955 scopus 로고    scopus 로고
    • Toll-like receptor 9 binds single-stranded CpG-DNA in a sequence- and pH-dependent manner
    • 10.1002/eji.200425218 15307186
    • Toll-like receptor 9 binds single-stranded CpG-DNA in a sequence- and pH-dependent manner. Rutz M, Metzger J, Gellert T, Luppa P, Lipford GB, Wagner H, Bauer S, Eur J Immunol 2004 34 2541 2550 10.1002/eji.200425218 15307186
    • (2004) Eur J Immunol , vol.34 , pp. 2541-2550
    • Rutz, M.1    Metzger, J.2    Gellert, T.3    Luppa, P.4    Lipford, G.B.5    Wagner, H.6    Bauer, S.7
  • 16
    • 28744458387 scopus 로고    scopus 로고
    • CpG oligodeoxynucleotides induce IL-8 expression in CD34+ cells via mitogen-activated protein kinase-dependent and NF-kappaB-independent pathways
    • 10.1093/intimm/dxh345 16263754
    • CpG oligodeoxynucleotides induce IL-8 expression in CD34+ cells via mitogen-activated protein kinase-dependent and NF-kappaB-independent pathways. Kim JM, Kim NI, Oh YK, Kim YJ, Youn J, Ahn MJ, Int Immunol 2005 17 1525 1531 10.1093/intimm/dxh345 16263754
    • (2005) Int Immunol , vol.17 , pp. 1525-1531
    • Kim, J.M.1    Kim, N.I.2    Oh, Y.K.3    Kim, Y.J.4    Youn, J.5    Ahn, M.J.6
  • 17
    • 33744955094 scopus 로고    scopus 로고
    • TLR9 is required for the gut-associated lymphoid tissue response following oral infection of Toxoplasma gondii
    • 10.4049/jimmunol.176.12.7589 16751405
    • TLR9 is required for the gut-associated lymphoid tissue response following oral infection of Toxoplasma gondii. Minns LA, Menard LC, Foureau DM, Darche S, Ronet C, Mielcarz DW, Buzoni-Gatel D, Kasper LH, J Immunol 2006 176 7589 7597 10.4049/jimmunol.176.12.7589 16751405
    • (2006) J Immunol , vol.176 , pp. 7589-7597
    • Minns, L.A.1    Menard, L.C.2    Foureau, D.M.3    Darche, S.4    Ronet, C.5    Mielcarz, D.W.6    Buzoni-Gatel, D.7    Kasper, L.H.8
  • 18
    • 84893115383 scopus 로고    scopus 로고
    • Innate immunity to Toxoplasma gondii infection
    • 10.1038/nri3598 24457485
    • Innate immunity to Toxoplasma gondii infection. Yarovinsky F, Nat Rev Immunol 2014 14 109 121 10.1038/nri3598 24457485
    • (2014) Nat Rev Immunol , vol.14 , pp. 109-121
    • Yarovinsky, F.1
  • 20
    • 68349131303 scopus 로고    scopus 로고
    • Gut commensal bacteria direct a protective immune response against Toxoplasma gondii
    • 10.1016/j.chom.2009.06.005 19683684
    • Gut commensal bacteria direct a protective immune response against Toxoplasma gondii. Benson A, Pifer R, Behrendt CL, Hooper LV, Yarovinsky F, Cell Host Microbe 2009 6 187 196 10.1016/j.chom.2009.06.005 19683684
    • (2009) Cell Host Microbe , vol.6 , pp. 187-196
    • Benson, A.1    Pifer, R.2    Behrendt, C.L.3    Hooper, L.V.4    Yarovinsky, F.5
  • 21
    • 0034658617 scopus 로고    scopus 로고
    • IL-10 is required for prevention of necrosis in the small intestine and mortality in both genetically resistant BALB/c and susceptible C57BL/6 mice following peroral infection with Toxoplasma gondii
    • 10.4049/jimmunol.164.10.5375 10799901
    • IL-10 is required for prevention of necrosis in the small intestine and mortality in both genetically resistant BALB/c and susceptible C57BL/6 mice following peroral infection with Toxoplasma gondii. Suzuki Y, Sher A, Yap G, Park D, Neyer LE, Liesenfeld O, Fort M, Kang H, Gufwoli E, J Immunol 2000 164 5375 5382 10.4049/jimmunol.164.10.5375 10799901
    • (2000) J Immunol , vol.164 , pp. 5375-5382
    • Suzuki, Y.1    Sher, A.2    Yap, G.3    Park, D.4    Neyer, L.E.5    Liesenfeld, O.6    Fort, M.7    Kang, H.8    Gufwoli, E.9
  • 23
    • 84897138296 scopus 로고    scopus 로고
    • Role of the microbiota in immunity and inflammation
    • 10.1016/j.cell.2014.03.011 24679531
    • Role of the microbiota in immunity and inflammation. Belkaid Y, Hand TW, Cell 2014 157 121 141 10.1016/j.cell.2014.03.011 24679531
    • (2014) Cell , vol.157 , pp. 121-141
    • Belkaid, Y.1    Hand, T.W.2
  • 26
    • 33751074136 scopus 로고    scopus 로고
    • Quantitative PCR assays for mouse enteric flora reveal strain-dependent differences in composition that are influenced by the microenvironment
    • 10.1007/s00335-006-0063-1 17091319
    • Quantitative PCR assays for mouse enteric flora reveal strain-dependent differences in composition that are influenced by the microenvironment. Deloris Alexander A, Orcutt RP, Henry JC, Baker JJR, Bissahoyo AC, Threadgill DW, Mamm Genome 2006 17 1093 1104 10.1007/s00335-006-0063-1 17091319
    • (2006) Mamm Genome , vol.17 , pp. 1093-1104
    • Deloris Alexander, A.1    Orcutt, R.P.2    Henry, J.C.3    Baker, J.J.R.4    Bissahoyo, A.C.5    Threadgill, D.W.6
  • 27
    • 33746102914 scopus 로고    scopus 로고
    • Colonization dynamics of altered Schaedler flora is influenced by gender, aging, and Helicobacter hepaticus infection in the intestines of Swiss Webster mice
    • 10.1128/AEM.01934-05 16820515
    • Colonization dynamics of altered Schaedler flora is influenced by gender, aging, and Helicobacter hepaticus infection in the intestines of Swiss Webster mice. Ge Z, Feng Y, Taylor NS, Ohtani M, Polz MF, Schauer DB, Fox JG, Appl Environ Microbiol 2006 72 5100 5103 10.1128/AEM.01934-05 16820515
    • (2006) Appl Environ Microbiol , vol.72 , pp. 5100-5103
    • Ge, Z.1    Feng, Y.2    Taylor, N.S.3    Ohtani, M.4    Polz, M.F.5    Schauer, D.B.6    Fox, J.G.7
  • 28
    • 34548145147 scopus 로고    scopus 로고
    • Epithelial barrier disruption allows nondisease-causing bacteria to initiate and sustain IBD in the IL-10 gene-deficient mouse
    • 10.1002/ibd.20155 17427241
    • Epithelial barrier disruption allows nondisease-causing bacteria to initiate and sustain IBD in the IL-10 gene-deficient mouse. Sydora BC, Macfarlane SM, Walker JW, Dmytrash AL, Churchill TA, Doyle J, Fedorak RN, Inflamm Bowel Dis 2007 13 947 954 10.1002/ibd.20155 17427241
    • (2007) Inflamm Bowel Dis , vol.13 , pp. 947-954
    • Sydora, B.C.1    Macfarlane, S.M.2    Walker, J.W.3    Dmytrash, A.L.4    Churchill, T.A.5    Doyle, J.6    Fedorak, R.N.7
  • 29
    • 79956078164 scopus 로고    scopus 로고
    • Commensal Bacteroides species induce colitis in host-genotype-specific fashion in a mouse model of inflammatory bowel disease
    • 10.1016/j.chom.2011.04.009 21575910
    • Commensal Bacteroides species induce colitis in host-genotype-specific fashion in a mouse model of inflammatory bowel disease. Bloom SM, Bijanki VN, Nava GM, Sun L, Malvin NP, Donermeyer DL, Dunne WMJR, Allen PM, Stappenbeck TS, Cell Host Microbe 2011 9 390 403 10.1016/j.chom.2011.04.009 21575910
    • (2011) Cell Host Microbe , vol.9 , pp. 390-403
    • Bloom, S.M.1    Bijanki, V.N.2    Nava, G.M.3    Sun, L.4    Malvin, N.P.5    Donermeyer, D.L.6    Dunne, W.7    Allen, P.M.8    Stappenbeck, T.S.9
  • 30
    • 38649115342 scopus 로고    scopus 로고
    • Microbial influences in inflammatory bowel diseases
    • 10.1053/j.gastro.2007.11.059 18242222
    • Microbial influences in inflammatory bowel diseases. Sartor RB, Gastroenterology 2008 134 577 594 10.1053/j.gastro.2007.11.059 18242222
    • (2008) Gastroenterology , vol.134 , pp. 577-594
    • Sartor, R.B.1
  • 31
    • 78649693004 scopus 로고    scopus 로고
    • Genetics and environmental interactions shape the intestinal microbiome to promote inflammatory bowel disease versus mucosal homeostasis
    • 10.1053/j.gastro.2010.10.036 21029802
    • Genetics and environmental interactions shape the intestinal microbiome to promote inflammatory bowel disease versus mucosal homeostasis. Sartor RB, Gastroenterology 2010 139 1816 1819 10.1053/j.gastro.2010.10.036 21029802
    • (2010) Gastroenterology , vol.139 , pp. 1816-1819
    • Sartor, R.B.1
  • 34
    • 84902536179 scopus 로고    scopus 로고
    • Spinal cord pathology in chronic experimental Toxoplasma gondii infection
    • 10.1556/EuJMI.4.2014.1.6 24678407
    • Spinal cord pathology in chronic experimental Toxoplasma gondii infection. Mohle L, Parlog A, Pahnke J, Dunay IR, Eur J Microbiol Immunol (Bp) 2014 4 65 75 10.1556/EuJMI.4.2014.1.6 24678407
    • (2014) Eur J Microbiol Immunol (Bp) , vol.4 , pp. 65-75
    • Mohle, L.1    Parlog, A.2    Pahnke, J.3    Dunay, I.R.4
  • 35
    • 48749107414 scopus 로고    scopus 로고
    • Gr1 (+) inflammatory monocytes are required for mucosal resistance to the pathogen Toxoplasma gondii
    • 10.1016/j.immuni.2008.05.019 18691912
    • Gr1 (+) inflammatory monocytes are required for mucosal resistance to the pathogen Toxoplasma gondii. Dunay IR, Damatta A, Fux B, Presti R, Greco S, Colonna M, Sibley LD, Immunity 2008 29 306 317 10.1016/j.immuni.2008.05.019 18691912
    • (2008) Immunity , vol.29 , pp. 306-317
    • Dunay, I.R.1    Damatta, A.2    Fux, B.3    Presti, R.4    Greco, S.5    Colonna, M.6    Sibley, L.D.7
  • 36
    • 84885446123 scopus 로고    scopus 로고
    • Encephalopathy of infection and systemic inflammation
    • 10.1097/WNP.0b013e3182a73d83 24084178
    • Encephalopathy of infection and systemic inflammation. Young GB, J Clin Neurophysiol 2013 30 454 461 10.1097/WNP.0b013e3182a73d83 24084178
    • (2013) J Clin Neurophysiol , vol.30 , pp. 454-461
    • Young, G.B.1
  • 37
    • 34247468864 scopus 로고    scopus 로고
    • Expression and distribution of Toll-like receptors in the brain during murine neurocysticercosis
    • 10.1016/j.jneuroim.2006.07.019 17011049
    • Expression and distribution of Toll-like receptors in the brain during murine neurocysticercosis. Mishra BB, Mishra PK, Teale JM, J Neuroimmunol 2006 181 46 56 10.1016/j.jneuroim.2006.07.019 17011049
    • (2006) J Neuroimmunol , vol.181 , pp. 46-56
    • Mishra, B.B.1    Mishra, P.K.2    Teale, J.M.3
  • 38
    • 79952575531 scopus 로고    scopus 로고
    • Evaluating the role of Toll-like receptors in diseases of the central nervous system
    • 10.1016/j.bcp.2011.01.003 21241665
    • Evaluating the role of Toll-like receptors in diseases of the central nervous system. Carty M, Bowie AG, Biochem Pharmacol 2011 81 825 837 10.1016/j.bcp.2011.01.003 21241665
    • (2011) Biochem Pharmacol , vol.81 , pp. 825-837
    • Carty, M.1    Bowie, A.G.2
  • 39
    • 0036364862 scopus 로고    scopus 로고
    • Inflammatory bowel disease: Is the intestine a Trojan horse?
    • 10.3184/003685002783238861 11969118
    • Inflammatory bowel disease: is the intestine a Trojan horse? Basset C, Holton J, Sci Prog 2002 85 33 56 10.3184/003685002783238861 11969118
    • (2002) Sci Prog , vol.85 , pp. 33-56
    • Basset, C.1    Holton, J.2
  • 40
    • 77953028565 scopus 로고    scopus 로고
    • Down-regulation of adhesion molecules and matrix metalloproteinases by ZK 156979 in inflammatory bowel diseases
    • 10.1016/j.clim.2010.03.004 20399147
    • Down-regulation of adhesion molecules and matrix metalloproteinases by ZK 156979 in inflammatory bowel diseases. Martinesi M, Treves C, Bonanomi AG, Milla M, Bagnoli S, Zuegel, Steinmeyer UA, Stio M, Clin Immunol 2010 136 51 60 10.1016/j.clim.2010.03.004 20399147
    • (2010) Clin Immunol , vol.136 , pp. 51-60
    • Martinesi, M.1    Treves, C.2    Bonanomi, A.G.3    Milla, M.4    Bagnoli, S.5    Zuegel6    Steinmeyer, U.A.7    Stio, M.8
  • 41
    • 6044263423 scopus 로고    scopus 로고
    • An orally active matrix metalloproteinase inhibitor, ONO-4817, reduces dextran sulfate sodium-induced colitis in mice
    • 10.1007/s00011-004-1281-1 15550999
    • An orally active matrix metalloproteinase inhibitor, ONO-4817, reduces dextran sulfate sodium-induced colitis in mice. Naito Y, Takagi T, Kuroda M, Katada K, Ichikawa H, Kokura S, Yoshida N, Okanoue NT, Yoshikawa T, Inflamm Res 2004 53 462 468 10.1007/s00011-004-1281-1 15550999
    • (2004) Inflamm Res , vol.53 , pp. 462-468
    • Naito, Y.1    Takagi, T.2    Kuroda, M.3    Katada, K.4    Ichikawa, H.5    Kokura, S.6    Yoshida, N.7    Okanoue, N.T.8    Yoshikawa, T.9
  • 42
    • 0033536007 scopus 로고    scopus 로고
    • Matrix metalloproteinase deficiencies affect contact hypersensitivity: Stromelysin-1 deficiency prevents the response and gelatinase B deficiency prolongs the response
    • 10.1073/pnas.96.12.6885 10359808
    • Matrix metalloproteinase deficiencies affect contact hypersensitivity: stromelysin-1 deficiency prevents the response and gelatinase B deficiency prolongs the response. Wang M, Qin X, Mudgett JS, Ferguson TA, Senior RM, Welgus HG, Proc Natl Acad Sci U S A 1999 96 6885 6889 10.1073/pnas.96.12.6885 10359808
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 6885-6889
    • Wang, M.1    Qin, X.2    Mudgett, J.S.3    Ferguson, T.A.4    Senior, R.M.5    Welgus, H.G.6
  • 44
    • 84902547792 scopus 로고    scopus 로고
    • Can microbiota transplantation abrogate murine colonization resistance against Campylobacter jejuni?
    • 10.1556/EuJMI.3.2013.1.5 24265916
    • Can microbiota transplantation abrogate murine colonization resistance against Campylobacter jejuni? Heimesaat MM, Plickert R, Fischer A, Göbel UB, Bereswill S, Eur J Microbiol Immunol (Bp) 2013 3 36 43 10.1556/EuJMI.3.2013. 1.5 24265916
    • (2013) Eur J Microbiol Immunol (Bp) , vol.3 , pp. 36-43
    • Heimesaat, M.M.1    Plickert, R.2    Fischer, A.3    Göbel, U.B.4    Bereswill, S.5
  • 46
    • 84863700148 scopus 로고    scopus 로고
    • Campylobacter jejuni induces acute enterocolitis in gnotobiotic IL-10-/- mice via Toll-like-receptor-2 and -4 signaling
    • 10.1371/journal.pone.0040761 22808254
    • Campylobacter jejuni induces acute enterocolitis in gnotobiotic IL-10-/- mice via Toll-like-receptor-2 and -4 signaling. Haag LM, Fischer A, Otto B, Plickert R, Kühl AA, Göbel UB, Bereswill S, Heimesaat MM, PLoS One 2012 7 40761 10.1371/journal.pone.0040761 22808254
    • (2012) PLoS One , vol.7 , pp. 540761
    • Haag, L.M.1    Fischer, A.2    Otto, B.3    Plickert, R.4    Kühl, A.A.5    Göbel, U.B.6    Bereswill, S.7    Heimesaat, M.M.8
  • 47
    • 84897858574 scopus 로고    scopus 로고
    • Survey of extra-intestinal immune responses in asymptomatic long-term Campylobacter jejuni-infected mice
    • 10.1556/EuJMI.3.2013.3.4 24265935
    • Survey of extra-intestinal immune responses in asymptomatic long-term Campylobacter jejuni-infected mice. Heimesaat MM, Haag LM, Fischer A, Otto B, Kühl AA, Göbel UB, Bereswill S, Eur J Microbiol Immunol (Bp) 2013 3 174 182 10.1556/EuJMI.3.2013.3.4 24265935
    • (2013) Eur J Microbiol Immunol (Bp) , vol.3 , pp. 174-182
    • Heimesaat, M.M.1    Haag, L.M.2    Fischer, A.3    Otto, B.4    Kühl, A.A.5    Göbel, U.B.6    Bereswill, S.7
  • 48
    • 84883810743 scopus 로고    scopus 로고
    • Small intestinal nematode infection of mice is associated with increased enterobacterial loads alongside the intestinal tract
    • 10.1371/journal.pone.0074026 24040152
    • Small intestinal nematode infection of mice is associated with increased enterobacterial loads alongside the intestinal tract. Rausch S, Held J, Fischer A, Heimesaat MM, Kühl AA, Bereswill S, Hartmann S, PLoS One 2013 8 74026 10.1371/journal.pone.0074026 24040152
    • (2013) PLoS One , vol.8 , pp. 574026
    • Rausch, S.1    Held, J.2    Fischer, A.3    Heimesaat, M.M.4    Kühl, A.A.5    Bereswill, S.6    Hartmann, S.7
  • 49
    • 84863759969 scopus 로고    scopus 로고
    • Comprehensive postmortem analyses of intestinal microbiota changes and bacterial translocation in human flora associated mice
    • 10.1371/journal.pone.0040758 22808253
    • Comprehensive postmortem analyses of intestinal microbiota changes and bacterial translocation in human flora associated mice. Heimesaat MM, Boelke S, Fischer A, Haag LM, Loddenkemper C, Kühl AA, Göbel UB, Bereswill S, PLoS One 2012 7 40758 10.1371/journal.pone.0040758 22808253
    • (2012) PLoS One , vol.7 , pp. 540758
    • Heimesaat, M.M.1    Boelke, S.2    Fischer, A.3    Haag, L.M.4    Loddenkemper, C.5    Kühl, A.A.6    Göbel, U.B.7    Bereswill, S.8
  • 50
    • 22144487678 scopus 로고    scopus 로고
    • A critical role for IL-10 in limiting inflammation during toxoplasmic encephalitis
    • 10.1016/j.jneuroim.2005.04.018 16005735
    • A critical role for IL-10 in limiting inflammation during toxoplasmic encephalitis. Wilson EH, Wille-Reece U, Dzierszinski F, Hunter CA, J Neuroimmunol 2005 165 63 74 10.1016/j.jneuroim.2005.04.018 16005735
    • (2005) J Neuroimmunol , vol.165 , pp. 63-74
    • Wilson, E.H.1    Wille-Reece, U.2    Dzierszinski, F.3    Hunter, C.A.4
  • 51
    • 80053460958 scopus 로고    scopus 로고
    • Toxoplasma gondii rhoptry kinase ROP16 activates STAT3 and STAT6 resulting in cytokine inhibition and arginase-1-dependent growth control
    • 10.1371/journal.ppat.1002236 21931552
    • Toxoplasma gondii rhoptry kinase ROP16 activates STAT3 and STAT6 resulting in cytokine inhibition and arginase-1-dependent growth control. Butcher BA, Fox BA, Rommereim LM, Kim SG, Maure KJ, Yarovinsky F, Herbert DR, Bzik DJ, Denker EY, PLoS Pathog 2011 7 1002236 10.1371/journal.ppat.1002236 21931552
    • (2011) PLoS Pathog , vol.7 , pp. 51002236
    • Butcher, B.A.1    Fox, B.A.2    Rommereim, L.M.3    Kim, S.G.4    Maure, K.J.5    Yarovinsky, F.6    Herbert, D.R.7    Bzik, D.J.8    Denker, E.Y.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.