Induced pluripotent stem cell-derived cardiomyocytes for drug development and toxicity testing

Pharmacology and Therapeutics

Volumn 143, Issue 2, 2014, Pages 246-252

  Sinnecker, Daniel ^a   Laugwitz, Karl Ludwig ^a,b   Moretti, Alessandra ^a,b  

^a TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^b DZHK GERMAN CENTRE FOR CARDIOVASCULAR RESEARCH   (Germany)

Author keywords

Drug screening; Drug toxicity; High throughput screening; iPSC; QT prolongation

Indexed keywords

POTASSIUM CHANNEL HERG; POTASSIUM CHANNEL KCNQ1;

ARTICLE; CARDIOTOXICITY; CELL DIFFERENTIATION; CELL ISOLATION; CELL MATURATION; CONTROL GROUP; DISEASE MODEL; DRUG DEVELOPMENT; DRUG SAFETY; DRUG SCREENING; DRUG TARGETING; HEART MUSCLE CELL; HUMAN; NONHUMAN; NUCLEAR REPROGRAMMING; PHENOTYPE; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; TOXICITY TESTING; PHYSIOLOGY; PROCEDURES;

CELL DIFFERENTIATION; CELLULAR REPROGRAMMING; DRUG DISCOVERY; HUMANS; INDUCED PLURIPOTENT STEM CELLS; MYOCYTES, CARDIAC; TOXICITY TESTS;

EID: 84902549826     PISSN: 01637258     EISSN: 1879016X     Source Type: Journal    
DOI: 10.1016/j.pharmthera.2014.03.004     Document Type: Review

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