Disease characterization using LQTS-specific induced pluripotent stem cells

Cardiovascular Research

Volumn 95, Issue 4, 2012, Pages 419-429

  Egashira, Toru ^a   Yuasa, Shinsuke ^a   Suzuki, Tomoyuki ^a,b   Aizawa, Yoshiyasu ^a   Yamakawa, Hiroyuki ^a   Matsuhashi, Tomohiro ^a   Ohno, Yohei ^a   Tohyama, Shugo ^a   Okata, Shinichiro ^c   Seki, Tomohisa ^a   Kuroda, Yusuke ^a,b   Yae, Kojiro ^a   Hashimoto, Hisayuki ^a   Tanaka, Tomofumi ^a,d   Hattori, Fumiyuki ^a,d   Sato, Toshiaki ^a   Miyoshi, Shunichiro ^a   Takatsuki, Seiji ^a   Murata, Mitsushige ^a   Kurokawa, Junko ^c   Furukawa, Tetsushi ^c   Makita, Naomasa ^e   Aiba, Takeshi ^f   Shimizu, Wataru ^f   Horie, Minoru ^g   Kamiya, Kaichiro ^b   Kodama, Itsuo ^b   Ogawa, Satoshi ^a   Fukuda, Keiichi ^a   more..

^a KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b NAGOYA UNIVERSITY   (Japan)

^c TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^d DAIICHI SANKYO CO   (Japan)

^e NAGASAKI UNIVERSITY GRADUATE SCHOOL OF BIOMEDICAL SCIENCES   (Japan)

^f NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER   (Japan)

^g SHIGA UNIVERSITY OF MEDICAL SCIENCE   (Japan)

Author keywords

Cardiomyocytes; Drug examination; iPS cells; Long QT syndrome; Personalized medicine

Indexed keywords

1 [2 (6 METHYL 2 PYRIDYL)ETHYL] 4 (4 METHYLSULFONYLAMINOBENZOYL)PIPERIDINE; CHROMANOL 293B; INTERMEDIATE CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARDIAC PATIENT; CELL DIFFERENTIATION; CELL MIGRATION; CONTROLLED STUDY; DRUG RESPONSE; ELECTRICAL POTENTIAL PARAMETERS; EMBRYO; EMBRYOID BODY; GENE MUTATION; GENETIC AND FAMILIAL DISORDERS; GENETIC ASSOCIATION; HEART ARRHYTHMIA; HEART FUNCTION TEST; HEART MUSCLE CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LONG QT SYNDROME; MOUSE; NONHUMAN; PATCH CLAMP; PLURIPOTENT STEM CELL; PRIORITY JOURNAL;

ACTION POTENTIALS; ADOLESCENT; ANIMALS; CELL DIFFERENTIATION; COCULTURE TECHNIQUES; EMBRYOID BODIES; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENETIC PREDISPOSITION TO DISEASE; HEK293 CELLS; HUMANS; INDUCED PLURIPOTENT STEM CELLS; INTERMEDIATE-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS; KCNQ1 POTASSIUM CHANNEL; MALE; MICE; MYOCYTES, CARDIAC; NUCLEAR REPROGRAMMING; PATCH-CLAMP TECHNIQUES; PHENOTYPE; POTASSIUM CHANNEL BLOCKERS; POTASSIUM CHANNELS, VOLTAGE-GATED; ROMANO-WARD SYNDROME; TERATOMA; TIME FACTORS; TRANSFECTION;

EID: 84865254838     PISSN: 00086363     EISSN: 17553245     Source Type: Journal    
DOI: 10.1093/cvr/cvs206     Document Type: Article

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