PTPRG inhibition by DNA methylation and cooperation with RAS gene activation in childhood acute lymphoblastic leukemia

International Journal of Cancer

Volumn 135, Issue 5, 2014, Pages 1101-1109

  Xiao, Jianqiao ^a   Lee, Seung Tae ^a,b   Xiao, Yuanyuan ^a   Ma, Xiaomei ^c   Andres Houseman, E ^d   Hsu, Ling I ^e   Roy, Ritu ^f   Wrensch, Margaret ^a   De Smith, Adam J ^a   Chokkalingam, Anand ^e   Buffler, Patricia ^e   Wiencke, John K ^a   Wiemels, Joseph L ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b Sungkyunkwan University School of Medicine   (South Korea)

^c YALE UNIVERSITY   (United States)

^d OREGON STATE UNIVERSITY   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

^f UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

childhood acute lymphoblastic leukemia; DNA methylation; PTPRG; RAS

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR RREB1; UNCLASSIFIED DRUG;

ACUTE LYMPHOBLASTIC LEUKEMIA; ARTICLE; CARCINOGENESIS; CELL GROWTH; CHILD; CHILDHOOD CANCER; CONTROLLED STUDY; DISEASE ASSOCIATION; DNA METHYLATION; GENE; GENE ACTIVATION; GENE EXPRESSION REGULATION; GENE LOCUS; GENE MUTATION; GENETIC ASSOCIATION; HUMAN; MAJOR CLINICAL STUDY; ONCOGENE RAS; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN DEPHOSPHORYLATION; PTPRG GENE;

CHILDHOOD ACUTE LYMPHOBLASTIC LEUKEMIA; DNA METHYLATION; PTPRG; RAS;

CELL TRANSFORMATION, NEOPLASTIC; CHILD; CHILD, PRESCHOOL; DNA METHYLATION; DNA-BINDING PROTEINS; ENZYME ACTIVATION; EPIGENESIS, GENETIC; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GENE EXPRESSION REGULATION, LEUKEMIC; HEK293 CELLS; HUMANS; MUTATION; PHOSPHORYLATION; PRECURSOR CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; PROMOTER REGIONS, GENETIC; RAS PROTEINS; RECEPTOR-LIKE PROTEIN TYROSINE PHOSPHATASES, CLASS 5; TRANSCRIPTION FACTORS; TRANSCRIPTIONAL ACTIVATION;

EID: 84902547885     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.28759     Document Type: Article

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