Identification of Preleukemic Precursors of Hyperdiploid Acute Lymphoblastic Leukemia in Cord Blood

Genes Chromosomes and Cancer

Volumn 40, Issue 1, 2004, Pages 38-43

  Maia, Ana Teresa ^a   Tussiwand, Roxane ^b   Cazzaniga, Giovanni ^b   Rebulla, Paolo ^c   Colman, Susan ^a   Biondi, Andrea ^b   Greaves, Mel ^a  

^a INSTITUTE OF CANCER RESEARCH   (United Kingdom)

^b UNIVERSITY OF MILANO BICOCCA   (Italy)

^c FONDAZIONE IRCCS CA GRANDA OSPEDALE MAGGIORE POLICLINICO   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CD19 ANTIGEN; CD3 ANTIGEN; CD33 ANTIGEN; CD34 ANTIGEN; DNA;

ACUTE LEUKEMIA; ACUTE LYMPHOBLASTIC LEUKEMIA; ARTICLE; B LYMPHOCYTE; CHILD; CHILDHOOD LEUKEMIA; CHROMOSOME 15; CHROMOSOME 17; CHROMOSOME TRANSLOCATION; CLINICAL ARTICLE; CONTROLLED STUDY; DIPLOIDY; FLUORESCENCE IN SITU HYBRIDIZATION; HEMATOPOIESIS; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; IMMUNOPHENOTYPING; KARYOTYPE; PRIORITY JOURNAL; UMBILICAL CORD BLOOD;

ANTIGENS, CD19; ANTIGENS, CD34; B-LYMPHOCYTES; CHILD; CHILD, PRESCHOOL; FEMALE; FETAL BLOOD; HLA-DR ANTIGENS; HUMANS; INFANT; KARYOTYPING; LEUKEMIA, LYMPHOCYTIC, ACUTE; MALE; POLYPLOIDY; PRELEUKEMIA; STEM CELLS;

EID: 1942453760     PISSN: 10452257     EISSN: None     Source Type: Journal    
DOI: 10.1002/gcc.20010     Document Type: Article

References (30)

1. Andreasson P, Schwaller J, Anastasiadou E, Aster J, Gilliland DG. 2001. The expression of ETV6/CBF2 (TEL/AML1) is not sufficient for the transformation of hematopoietic cell lines in vitro or the induction of hematologic disease in vivo. Cancer Genet Cytogenet 130:93-104.
2. Fasching K, Panzer S, Haas OA, Marschalek R, Gadner H, Panzer-Grümayer ER. 2000. Presence of clone-specific antigen receptor gene rearrangements at birth indicates an in utero origin of diverse types of early childhood acute lymphoblastic leukemia. Blood 95:2722-2724.
3. Ford AM, Ridge SA, Cabrera ME, Mahmoud H, Steel CM, Chan LC, Greaves MF. 1993. In utero rearrangements in the trithorax-related oncogene in infant leukaemias. Nature 363:358-360.
4. Ford AM, Bennett CA, Price CM, Bruin MCA, Van Wering ER, Greaves M. 1998. Fetal origins of the TEL-AML1 fusion gene in identical twins with leukemia. Proc Natl Acad Sci USA 95:4584-4588.
5. Gale KB, Ford AM, Repp R, Borkhardt A, Keller C, Eden OB, Greaves MF. 1997. Backtracking leukemia to birth: identification of clonotypic gene fusion sequences in neonatal blood spots. Proc Natl Acad Sci USA 94:13950-13954.
6. Gill Super HJ, Rothberg PG, Kobayashi H, Freeman Al, Diaz MO, Rowley JD. 1994. Clonal, nonconsitutional rearrangements of the MLL gene in infant twins with acute lymphoblastic leukemia: in utero chromosome rearrangement of 11q23. Blood 83:641-644.
7. Gilliland DG, Griffin JD. 2002. The roles of FLT3 in hematopoiesis and leukemia. Blood 100:1532-1542.
8. Greaves M. 1999. Molecular genetics, natural history and the demise of childhood leukaemia. Eur J Can 35:173-185.
9. Greaves MF, Wiemels J. 2003. Origins of chromosome translocations in childhood leukaemia. Nature Rev Cancer 3:639-649.
10. Greaves MF, Maia AT, Wiemels JL, Ford AM. 2003. Leukemia in twins: lessons in natural history. Blood 102:2321-2333.
11. Hjalgrim LL, Madsen HO, Melbye M, Jørgensen P, Christiansen M, Andersen MT, Pallisgaard N, Hokland P, Clausen N, Ryder LP, Schmiegelow K, Hjalgrim H. 2002. Presence of clone-specific markers at birth in children with acute lymphoblastic leukaemia. Br J Cancer 87:994-999.
12. - progenitor/stem cells in TEL/AML1-positive acute lymphoblastic leukemia are genetically and functionally normal. Blood 100:640-646.
13. LeBien TW. 2000. Fates of human B-cell precursors. Blood 96:9-23.
14. Maia AT, Ford AM, Jalali GR, Harrison CJ, Taylor GM, Eden OB, Greaves MF. 2001. Molecular tracking of leukemogenesis in a triplet pregnancy. Blood 98:478-482.
15. Maia AT, van der Velden VHJ, Harrison CJ, Szczepanski T, Williams MD, Griffiths MJ, van Dongen JJM, Greaves MF. 2003. Prenatal origin of hyperdiploid acute lymphoblastic leukemia in identical twins. Leukemia 17:2202-2206.
16. McHale CM, Wiemels JL, Zhang L, Ma X, Buffler PA, Feusner J, Matthay K, Dahl G, Smith MT. 2003. Prenatal origin of childhood acute myeloid leukemias harboring chromosomal rearrangements t(15;17) and inv(16). Blood 101:4640-4641.
17. Mori H, Colman SM, Xiao Z, Ford AM, Healy LE, Donaldson C, Hows JM, Navarrete C, Greaves M. 2002. Chromosome translocations and covert leukemic clones are generated during normal fetal development. Proc Natl Acad Sci USA 99:8242-8247.
18. Panzer-Grümayer ER, Fasching K, Panzer S, Hettinger K, Schmitt K, Stöckler-Ipsiroglu S, Haas OA. 2002. Nondisjunction of chromosomes leading to hyperdiploid childhood B-cell precursor acute lymphoblastic leukemia is an early event during leukemogenesis. Blood 100:347-349.
19. Price CM, Kanfer EJ, Colman SM, Westwood N, Barrett AJ, Greaves MF. 1992. Simultaneous genotypic and immunophenotypic analysis of interphase cells using dual-color fluorescence: a demonstration of lineage involvement in polycythemia vera. Blood 80:1033-1038.
20. Rabbitts TH. 1994. Chromosomal translocations in human cancer. Nature 372:143-149.
21. Raimondi SC. 1999. Cytogenetics of acute leukemias. In: Pui C-H, editor. Childhood leukemias. Cambridge, UK: Cambridge University Press. p 168-196.
22. Rowley JD. 1998. The critical role of chromosome translocations in human leukemias. Annu Rev Genet 32:495-519.
23. Taketani T, Taki T, Sugita K, Furuichi Y, Ishii E, Hanada R, Tsuchida M, Sugita K, Ida K, Hayashi Y. 2004. FLT3 mutations in the activation loop of tyrosine kinase doamin are frequently found in infant ALL with MLL rearrangements and pediatric ALL with hyperdiploidy. Blood 103:1085-1089.
24. Taub JW, Konrad MA, Ge Y, Naber JM, Scott JS, Matherly LH, Ravindranath Y. 2002. High frequency of leukemic clones in newborn screening blood samples of children with B-precursor acute lymphoblastic leukemia. Blood 99:2992-2996.
25. Verhagen OJ, Willemse MJ, Breunis WB, Wijkhuijs AJ, Jacobs DC, Joosten SA, van Wering ER, van Dongen JJ, van der Schoot CE. 2000. Application of germline IGH probes in real-time quantitative PCR for the detection of minimal residual disease in acute lymphoblastic leukemia. Leukemia 14:1426-1435.
26. Wiemels JL, Cazzaniga G, Daniotti M, Eden OB, Addison GM, Masera G, Saha V, Biondi A, Greaves MF. 1999a. Prenatal origin of acute lymphoblastic leukaemia in children. Lancet 354:1499-1503.
27. Wiemels JL, Ford AM, Van Wering ER, Postma A, Greaves M. 1999b. Protracted and variable latency of acute lymphoblastic leukemia after TEL-AML1 gene fusion in utero. Blood 94:1057-1062.
28. Wiemels JL, Xiao Z, Buffler PA, Maia AT, Ma X, Dicks BM, Smith MT, Zhang L, Feusner J, Wiencke J, Pritchard-Jones K, Kempski H, Greaves M. 2002. In utero origin of t(8;21) AML1-ETO translocations in childhood acute myeloid leukemia. Blood 99:3801-3805.
29. Yagi T, Hibi S, Tabata Y, Kuriyama K, Teramura T, Hashida T, Shimizu Y, Takimoto T, Todo S, Sawada T, Imashuku S. 2000. Detection of clonotypic IGH and TCR rearrangements in the neonatal blood spots of infants and children with B-cell precursor acute lymphoblastic leukemia. Blood 96:264-268.
30. Yuan Y, Zhou L, Miyamoto T, Iwasaki H, Harakawa N, Hetherington CJ, Burel SA, Lagasse E, Weissman IL, Akashi K, Zhang D-E. 2001. AML1-ETO expression is directly involved in the development of acute myeloid leukemia in the presence of additional mutations. Proc Natl Acad Sci USA 98:10398-10403.