Upregulation of tumor necrosis factor α and ADAMTS-5, but not ADAMTS-4, in human intervertebral cartilage endplate with modic changes

Spine

Volumn 39, Issue 14, 2014, Pages

  Chen, Shuai ^a,b   Huang, Yue ^a,b   Zhou, Zhi Jie ^a,b   Hu, Zhi Jun ^a,b   Wang, Ji Ying ^b   Xu, Wen Bin ^a,b   Fang, Xiang Qian ^a,b   Fan, Shun Wu ^a,b  

^a ZHEJIANG UNIVERSITY   (China)

^b Key Laboratory of Biotherapy   (China)

Author keywords

ADAMTS; Bovine endplate chondrocytes; Human cartilage endplate; Low back pain; Modic changes; NF B pathway; TNF

Indexed keywords

AGGRECAN; AGGRECANASE 1; AGGRECANASE 2; COLLAGEN TYPE 1; COLLAGEN TYPE 10; COLLAGEN TYPE 2; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; SCLEROPROTEIN; TUMOR NECROSIS FACTOR ALPHA; ADAM PROTEIN; ADAMTS5 PROTEIN, HUMAN; AGGRECANASE-1; PROCOLLAGEN N PROTEINASE;

ADULT; AGED; ANIMAL CELL; ANIMAL CELL CULTURE; ARTICLE; ARTICULAR CARTILAGE; CARTILAGE CELL; CLINICAL ARTICLE; CONTROLLED STUDY; EXTRACELLULAR MATRIX; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; INTERVERTEBRAL CARTILAGE ENDPLATE; INTERVERTEBRAL DISK; INTERVERTEBRAL DISK DEGENERATION; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONTENT; PROTEIN EXPRESSION; PROTEIN FUNCTION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TISSUE LEVEL; UPREGULATION; ADOLESCENT; ANIMAL; BOVINAE; CARTILAGE; GENETICS; LOW BACK PAIN; LUMBAR VERTEBRA; METABOLISM; MIDDLE AGED; PATHOLOGY; YOUNG ADULT;

ADAM PROTEINS; ADOLESCENT; ADULT; AGED; ANIMALS; CARTILAGE; CATTLE; CHONDROCYTES; HUMANS; INTERVERTEBRAL DISC; LOW BACK PAIN; LUMBAR VERTEBRAE; MIDDLE AGED; PROCOLLAGEN N-ENDOPEPTIDASE; TUMOR NECROSIS FACTOR-ALPHA; UP-REGULATION; YOUNG ADULT;

EID: 84902546384     PISSN: 03622436     EISSN: 15281159     Source Type: Journal    
DOI: 10.1097/BRS.0000000000000362     Document Type: Article

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