Steric hindrance between S4 and S5 of the KCNQ1/KCNE1 channel hampers pore opening

Nature Communications

Volumn 5, Issue , 2014, Pages

  Nakajo, Koichi ^a,b   Kubo, Yoshihiro ^a,b  

^a NATIONAL INSTITUTE FOR PHYSIOLOGICAL SCIENCES   (Japan)

^b Department of Physiological Sciences ^*  (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; AMINO ACID; ARGININE; CYSTEINE; PHENYLALANINE; POTASSIUM CHANNEL KCNE1; POTASSIUM CHANNEL KCNQ1; VALINE; KCNE1 PROTEIN, HUMAN; KCNQ1 PROTEIN, HUMAN; VOLTAGE GATED POTASSIUM CHANNEL;

AMINO ACID; MEMBRANE; POLARIZATION; PROTEIN; STABILIZATION;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DISULFIDE BOND; ION CURRENT; MEMBRANE DEPOLARIZATION; MEMBRANE POTENTIAL; NONHUMAN; SHORT QT SYNDROME; STATIC ELECTRICITY; STEREOSPECIFICITY; WILD TYPE; CELL MEMBRANE; CHEMICAL STRUCTURE; CHEMISTRY; GENETICS; HUMAN; METABOLISM; PROTEIN MOTIF;

AMINO ACID MOTIFS; CELL MEMBRANE; HUMANS; KCNQ1 POTASSIUM CHANNEL; MODELS, MOLECULAR; PHENYLALANINE; POTASSIUM CHANNELS, VOLTAGE-GATED;

EID: 84902532327     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms5100     Document Type: Article

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