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Volumn 8, Issue 4, 2014, Pages 133-144

Atorvastatin improves systolic function, but does not prevent the development of dilated cardiomyopathy in streptozotocin-induced diabetic rats

Author keywords

atorvastatin; cardiac function; cholesterol; endothelial function; oxidative stress; type 1 diabetic rats

Indexed keywords

ACETYLCHOLINE; ATORVASTATIN; CHOLESTEROL; MALONALDEHYDE; N(G) NITROARGININE METHYL ESTER; STREPTOZOCIN;

EID: 84902509850     PISSN: 17539447     EISSN: 17539455     Source Type: Journal    
DOI: 10.1177/1753944714531065     Document Type: Article
Times cited : (8)

References (48)
  • 1
    • 68649091453 scopus 로고    scopus 로고
    • Simvastatin alleviates myocardial contractile dysfunction and lethal ischemic injury in rat heart independent of cholesterol-lowering effects
    • Adameova A. Harcarova A. Matejikova J. Pancza D. Kuzelova M. Carnicka S. et al. (2009) Simvastatin alleviates myocardial contractile dysfunction and lethal ischemic injury in rat heart independent of cholesterol-lowering effects. Physiol Res 58: 449–454.
    • (2009) Physiol Res , vol.58 , pp. 449-454
    • Adameova, A.1    Harcarova, A.2    Matejikova, J.3    Pancza, D.4    Kuzelova, M.5    Carnicka, S.6
  • 2
    • 79953749538 scopus 로고    scopus 로고
    • Diabetes-induced peroxynitrite impairs the balance of pro-nerve growth factor and nerve growth factor, and causes neurovascular injury
    • Ali T. Al-Gayyar M. Matragoon S. Pillai B. Abdelsaid M. Nussbaum J. et al. (2011) Diabetes-induced peroxynitrite impairs the balance of pro-nerve growth factor and nerve growth factor, and causes neurovascular injury. Diabetologia 54: 657–668.
    • (2011) Diabetologia , vol.54 , pp. 657-668
    • Ali, T.1    Al-Gayyar, M.2    Matragoon, S.3    Pillai, B.4    Abdelsaid, M.5    Nussbaum, J.6
  • 3
    • 84871995815 scopus 로고    scopus 로고
    • Standards of medical care in diabetes 2013
    • American Diabetes Association
    • American Diabetes Association (2013) Standards of medical care in diabetes 2013. Diabetes Care 36(Suppl. 1): S11–S66.
    • (2013) Diabetes Care , vol.36 , pp. S11-S66
  • 5
    • 34247639532 scopus 로고    scopus 로고
    • Effect of coenzyme Q 10 on myopathic symptoms in patients treated with statins
    • Caso G. Kelly P. McNurlan M. Lawson W. (2007) Effect of coenzyme Q 10 on myopathic symptoms in patients treated with statins. Am J Cardiol 99: 1409–1412.
    • (2007) Am J Cardiol , vol.99 , pp. 1409-1412
    • Caso, G.1    Kelly, P.2    McNurlan, M.3    Lawson, W.4
  • 6
    • 33845985670 scopus 로고    scopus 로고
    • Differential impact of atorvastatin vs pravastatin on progressive insulin resistance and left ventricular diastolic dysfunction in a rat model of type II diabetes
    • Chen Y. Ohmori K. Mizukawa M. Yoshida J. Zeng Y. Zhang L. et al. (2007) Differential impact of atorvastatin vs pravastatin on progressive insulin resistance and left ventricular diastolic dysfunction in a rat model of type II diabetes. Circ J 71: 144–152.
    • (2007) Circ J , vol.71 , pp. 144-152
    • Chen, Y.1    Ohmori, K.2    Mizukawa, M.3    Yoshida, J.4    Zeng, Y.5    Zhang, L.6
  • 7
    • 4344683381 scopus 로고    scopus 로고
    • Primary prevention of cardiovascular disease with atorvastatin in type 2 diabetes in the Collaborative Atorvastatin Diabetes Study (CARDS): multicentre randomised placebo–controlled trial
    • Colhoun H. Betteridge D. Durrington P. Hitman G. Neil H. Livingstone S. et al. (2004) Primary prevention of cardiovascular disease with atorvastatin in type 2 diabetes in the Collaborative Atorvastatin Diabetes Study (CARDS): multicentre randomised placebo–controlled trial. Lancet 64: 685–696.
    • (2004) Lancet , vol.64 , pp. 685-696
    • Colhoun, H.1    Betteridge, D.2    Durrington, P.3    Hitman, G.4    Neil, H.5    Livingstone, S.6
  • 8
    • 0030837996 scopus 로고    scopus 로고
    • High glucose increases nitric oxide synthase expression and superoxide anion generation in human aortic endothelial cells
    • Cosentino F. Hishikawa K. Katusic Z. Lüscher T. (1997) High glucose increases nitric oxide synthase expression and superoxide anion generation in human aortic endothelial cells. Circulation 96: 25–28.
    • (1997) Circulation , vol.96 , pp. 25-28
    • Cosentino, F.1    Hishikawa, K.2    Katusic, Z.3    Lüscher, T.4
  • 9
    • 0035667921 scopus 로고    scopus 로고
    • Biochemical functions of coenzyme Q10
    • Crane F. (2001) Biochemical functions of coenzyme Q10. J Am Coll Nutr 20: 591–598.
    • (2001) J Am Coll Nutr , vol.20 , pp. 591-598
    • Crane, F.1
  • 10
    • 4944221251 scopus 로고    scopus 로고
    • Enalapril improves vascular and cardiac function in STZ-diabetic rats
    • Crespo M. Dunbar D. (2003) Enalapril improves vascular and cardiac function in STZ-diabetic rats. Mol Cell Biol 49: 1311–1318.
    • (2003) Mol Cell Biol , vol.49 , pp. 1311-1318
    • Crespo, M.1    Dunbar, D.2
  • 11
    • 80053079640 scopus 로고    scopus 로고
    • Diabetes alters cardiovascular responses to anaesthetic induction agents in STZ-diabetic rats
    • Crespo M. Marrero M. Cruz N. Quidgley J. Creagh O. Torres H. et al. (2011) Diabetes alters cardiovascular responses to anaesthetic induction agents in STZ-diabetic rats. Diab Vasc Dis Res 8: 299–302.
    • (2011) Diab Vasc Dis Res , vol.8 , pp. 299-302
    • Crespo, M.1    Marrero, M.2    Cruz, N.3    Quidgley, J.4    Creagh, O.5    Torres, H.6
  • 12
    • 0037230550 scopus 로고    scopus 로고
    • Cardiovascular deterioration in STZ-diabetic rats: possible role of vascular RAS
    • Crespo M. Moreta S. Gonzalez J. (2003) Cardiovascular deterioration in STZ-diabetic rats: possible role of vascular RAS. Pharmacology 68: 1–8.
    • (2003) Pharmacology , vol.68 , pp. 1-8
    • Crespo, M.1    Moreta, S.2    Gonzalez, J.3
  • 13
    • 39049157265 scopus 로고    scopus 로고
    • Cardiac oxidative stress is elevated at the onset of dilated cardiomyopathy in STZ-diabetic rats
    • Crespo M. Zalacaín J. Dunbar D. Cruz N. Arocho L. (2008) Cardiac oxidative stress is elevated at the onset of dilated cardiomyopathy in STZ-diabetic rats. J Cardiovasc Pharmacol Ther 13: 64–71.
    • (2008) J Cardiovasc Pharmacol Ther , vol.13 , pp. 64-71
    • Crespo, M.1    Zalacaín, J.2    Dunbar, D.3    Cruz, N.4    Arocho, L.5
  • 14
    • 0029837064 scopus 로고    scopus 로고
    • Lipid–lowering drugs and mitochondrial function: effects of HMG–CoA reductase inhibitors on serum ubiquinone and blood lactate / pyruvate ratio
    • de Pinieux G. Chariot P. Ammi-Saïd M. Louarn F. Lejonc J. Astier A. et al. (1996) Lipid–lowering drugs and mitochondrial function: effects of HMG–CoA reductase inhibitors on serum ubiquinone and blood lactate / pyruvate ratio. Br J Clin Pharmacol 42: 333–337.
    • (1996) Br J Clin Pharmacol , vol.42 , pp. 333-337
    • de Pinieux, G.1    Chariot, P.2    Ammi-Saïd, M.3    Louarn, F.4    Lejonc, J.5    Astier, A.6
  • 15
    • 14644392855 scopus 로고    scopus 로고
    • Statin therapy improves brachial artery vasodilator function in patients with Type 1 diabetes and microalbuminuria
    • Dogra G. Watts G. Chan D. Stanton K. (2005) Statin therapy improves brachial artery vasodilator function in patients with Type 1 diabetes and microalbuminuria. Diabet Med 22: 239–242.
    • (2005) Diabet Med , vol.22 , pp. 239-242
    • Dogra, G.1    Watts, G.2    Chan, D.3    Stanton, K.4
  • 16
    • 84869096206 scopus 로고    scopus 로고
    • Atorvastatin increases oxidative stress and modulates angiogenesis in Ossabaw swine with the metabolic syndrome
    • Elmadhun N. Lassaletta A. Chu L. Liu Y. Feng J. Sellke F. (2012) Atorvastatin increases oxidative stress and modulates angiogenesis in Ossabaw swine with the metabolic syndrome. J Thorac Cardiovasc Surg 144: 1486–1493.
    • (2012) J Thorac Cardiovasc Surg , vol.144 , pp. 1486-1493
    • Elmadhun, N.1    Lassaletta, A.2    Chu, L.3    Liu, Y.4    Feng, J.5    Sellke, F.6
  • 17
    • 80052718888 scopus 로고    scopus 로고
    • Atorvastatin worsens left ventricular diastolic dysfunction and endothelial dysfunction of epicardial coronary arteries in normocholesterolemic porcine with left ventricular hypertrophy
    • Forcillo J. Maltais S. Aubin M. Shi Y. Carrier M. Tardif J. et al. (2011) Atorvastatin worsens left ventricular diastolic dysfunction and endothelial dysfunction of epicardial coronary arteries in normocholesterolemic porcine with left ventricular hypertrophy. J Cardiovasc Pharmacol 58: 295–306.
    • (2011) J Cardiovasc Pharmacol , vol.58 , pp. 295-306
    • Forcillo, J.1    Maltais, S.2    Aubin, M.3    Shi, Y.4    Carrier, M.5    Tardif, J.6
  • 18
    • 84887167712 scopus 로고    scopus 로고
    • Effects of prior intensive versus conventional therapy and history of glycemia on cardiac function in type 1 diabetes in the DCCT/EDIC
    • Genuth S. Backlund J. Bayless M. Bluemke D. Cleary P. Crandall J. et al. (2013) Effects of prior intensive versus conventional therapy and history of glycemia on cardiac function in type 1 diabetes in the DCCT/EDIC. Diabetes 62: 3561–3569.
    • (2013) Diabetes , vol.62 , pp. 3561-3569
    • Genuth, S.1    Backlund, J.2    Bayless, M.3    Bluemke, D.4    Cleary, P.5    Crandall, J.6
  • 19
    • 84871867210 scopus 로고    scopus 로고
    • The role of nitric oxide on rosuvastatin-mediated S-nitrosylation and translational proteomes in human umbilical vein endothelial cells
    • Huang B. Li F. Wu C. Wang D. (2012) The role of nitric oxide on rosuvastatin-mediated S-nitrosylation and translational proteomes in human umbilical vein endothelial cells. Proteome Sci 10:43.
    • (2012) Proteome Sci , vol.10 , pp. 43
    • Huang, B.1    Li, F.2    Wu, C.3    Wang, D.4
  • 20
    • 0034058436 scopus 로고    scopus 로고
    • Altered membrane proteins and permeability correlate with cardiac dysfunction in cardiomyopathic hamsters
    • Ikeda Y. Martone M. Gu Y. Hoshijima M. Thor A. Oh S. et al. (2000) Altered membrane proteins and permeability correlate with cardiac dysfunction in cardiomyopathic hamsters. Am J Physiol Heart Circ Physiol 278: H1362–H1370.
    • (2000) Am J Physiol Heart Circ Physiol , vol.278 , pp. H1362-H1370
    • Ikeda, Y.1    Martone, M.2    Gu, Y.3    Hoshijima, M.4    Thor, A.5    Oh, S.6
  • 21
    • 77958462484 scopus 로고    scopus 로고
    • Atorvastatin upregulates nitric oxide synthases with Rho–kinase inhibition and Akt activation in the kidney of spontaneously hypertensive rats
    • Ito D. Ito O. Mori N. Muroya Y. Cao P. Takashima K. et al. (2010) Atorvastatin upregulates nitric oxide synthases with Rho–kinase inhibition and Akt activation in the kidney of spontaneously hypertensive rats. J Hypertens 28: 2278–2288.
    • (2010) J Hypertens , vol.28 , pp. 2278-2288
    • Ito, D.1    Ito, O.2    Mori, N.3    Muroya, Y.4    Cao, P.5    Takashima, K.6
  • 22
    • 0033432818 scopus 로고    scopus 로고
    • Abnormal cardiac function in the streptozotocin–induced non–insulin–dependent diabetic rat: noninvasive assessment with Doppler echocardiography and contribution of the nitric oxide pathway
    • Joffe I. Travers K. Perreault-Micale C. Hampton T. Katz S. Morgan J. et al. (1999) Abnormal cardiac function in the streptozotocin–induced non–insulin–dependent diabetic rat: noninvasive assessment with Doppler echocardiography and contribution of the nitric oxide pathway. J Am Coll Cardiol 34: 2111–2119.
    • (1999) J Am Coll Cardiol , vol.34 , pp. 2111-2119
    • Joffe, I.1    Travers, K.2    Perreault-Micale, C.3    Hampton, T.4    Katz, S.5    Morgan, J.6
  • 23
    • 50249145187 scopus 로고    scopus 로고
    • Effect of atorvastatin on endothelial function and inflammation in long-duration type 1 diabetic patients without coronary heart disease and arterial hypertension
    • Konduracka E. Galicka-Latala D. Cieslik G. Rostoff P. Fedak D. Sieradzki J. et al. (2008) Effect of atorvastatin on endothelial function and inflammation in long-duration type 1 diabetic patients without coronary heart disease and arterial hypertension. Diabetes Obes Metab 10: 719–725.
    • (2008) Diabetes Obes Metab , vol.10 , pp. 719-725
    • Konduracka, E.1    Galicka-Latala, D.2    Cieslik, G.3    Rostoff, P.4    Fedak, D.5    Sieradzki, J.6
  • 24
    • 64749086505 scopus 로고    scopus 로고
    • Relationship between spontaneous and iatrogenic hypoglycemia and mortality in patients hospitalized with acute myocardial infarction
    • Kosiborod M. Inzucchi S. Goyal A. Krumholz H. Masoudi F. Xiao L. et al. (2009) Relationship between spontaneous and iatrogenic hypoglycemia and mortality in patients hospitalized with acute myocardial infarction. J Am Med Assoc 30: 1556–1564.
    • (2009) J Am Med Assoc , vol.30 , pp. 1556-1564
    • Kosiborod, M.1    Inzucchi, S.2    Goyal, A.3    Krumholz, H.4    Masoudi, F.5    Xiao, L.6
  • 25
    • 0032584177 scopus 로고    scopus 로고
    • Upregulation of endothelial nitric oxide synthase by HMG CoA reductase inhibitors
    • Laufs U. La Fata V. Plutzky J. Liao J. (1998) Upregulation of endothelial nitric oxide synthase by HMG CoA reductase inhibitors. Circulation 97: 1129–1135.
    • (1998) Circulation , vol.97 , pp. 1129-1135
    • Laufs, U.1    La Fata, V.2    Plutzky, J.3    Liao, J.4
  • 26
    • 0028226079 scopus 로고
    • Serum ubiquinone concentrations after short- and long-term treatment with HMG-CoA reductase inhibitors
    • Laaksonen R. Ojala J. Tikkanen M. Himberg J. (1994) Serum ubiquinone concentrations after short- and long-term treatment with HMG-CoA reductase inhibitors. Eur J Clin Pharmacol 46: 313–317.
    • (1994) Eur J Clin Pharmacol , vol.46 , pp. 313-317
    • Laaksonen, R.1    Ojala, J.2    Tikkanen, M.3    Himberg, J.4
  • 27
    • 70749119012 scopus 로고    scopus 로고
    • Meta-analysis of randomized controlled trials of statins versus placebo in patients with heart failure
    • Lipinski M. Cauthen C. Biondi-Zoccai G. Abbate A. Vrtovec B. Khan B. et al. (2009) Meta-analysis of randomized controlled trials of statins versus placebo in patients with heart failure. Am J Cardiol 104: 1708–1716.
    • (2009) Am J Cardiol , vol.104 , pp. 1708-1716
    • Lipinski, M.1    Cauthen, C.2    Biondi-Zoccai, G.3    Abbate, A.4    Vrtovec, B.5    Khan, B.6
  • 28
    • 84874529858 scopus 로고    scopus 로고
    • Association between elevated blood glucose and outcome in acute heart failure: results from an international observational cohort
    • Mebazaa A. Gayat E. Lassus J. Meas T. Mueller C. Maggioni A. et al. (2013) Association between elevated blood glucose and outcome in acute heart failure: results from an international observational cohort. J Am Coll Cardiol 61: 820–829.
    • (2013) J Am Coll Cardiol , vol.61 , pp. 820-829
    • Mebazaa, A.1    Gayat, E.2    Lassus, J.3    Meas, T.4    Mueller, C.5    Maggioni, A.6
  • 29
    • 0034844049 scopus 로고    scopus 로고
    • Mortality and causes of death in the WHO Multinational Study of Vascular Disease in Diabetes
    • Morrish N. Wang S. Stevens L. Fuller J. Keen H. (2001) Mortality and causes of death in the WHO Multinational Study of Vascular Disease in Diabetes. Diabetologia 44: S14–S21.
    • (2001) Diabetologia , vol.44 , pp. S14-S21
    • Morrish, N.1    Wang, S.2    Stevens, L.3    Fuller, J.4    Keen, H.5
  • 30
    • 0031935559 scopus 로고    scopus 로고
    • Endothelial dysfunction in streptozotocin-diabetic rats is not reversed by dietary probucol or simvastatin supplementation
    • Palmer A. Gopaul N. Dhir S. Thomas C. Poston L. Tribe R. (1998) Endothelial dysfunction in streptozotocin-diabetic rats is not reversed by dietary probucol or simvastatin supplementation. Diabetologia 41: 157–164.
    • (1998) Diabetologia , vol.41 , pp. 157-164
    • Palmer, A.1    Gopaul, N.2    Dhir, S.3    Thomas, C.4    Poston, L.5    Tribe, R.6
  • 31
    • 34547635035 scopus 로고    scopus 로고
    • Low-dose treatment with atorvastatin leads to anti-oxidative and anti-inflammatory effects in diabetes mellitus
    • Riad A. Du J. Stiehl S. Westermann D. Mohr Z. Sobirey M. et al. (2007) Low-dose treatment with atorvastatin leads to anti-oxidative and anti-inflammatory effects in diabetes mellitus. Eur J Pharmacol 569: 204–211.
    • (2007) Eur J Pharmacol , vol.569 , pp. 204-211
    • Riad, A.1    Du, J.2    Stiehl, S.3    Westermann, D.4    Mohr, Z.5    Sobirey, M.6
  • 32
    • 2942587374 scopus 로고    scopus 로고
    • Atorvastatin decreases the coenzyme Q 10 level in the blood of patients at risk for cardiovascular disease and stroke
    • Rundek T. Naini A. Sacco R. Coates K. DiMauro S. (2004) Atorvastatin decreases the coenzyme Q 10 level in the blood of patients at risk for cardiovascular disease and stroke. Arch Neurol 61: 889–892.
    • (2004) Arch Neurol , vol.61 , pp. 889-892
    • Rundek, T.1    Naini, A.2    Sacco, R.3    Coates, K.4    DiMauro, S.5
  • 33
    • 84856108524 scopus 로고    scopus 로고
    • Relationship of endothelial nitric oxide synthase (eNOS) gene polymorphisms with diabetic retinopathy in Caucasians with type 2 diabetes
    • Santos K. Crispim D. Canani L. Ferrugem P. Gross J. Roisenberg I. (2012) Relationship of endothelial nitric oxide synthase (eNOS) gene polymorphisms with diabetic retinopathy in Caucasians with type 2 diabetes. Ophthalmic Genet 33: 23–27.
    • (2012) Ophthalmic Genet , vol.33 , pp. 23-27
    • Santos, K.1    Crispim, D.2    Canani, L.3    Ferrugem, P.4    Gross, J.5    Roisenberg, I.6
  • 35
    • 33644669967 scopus 로고    scopus 로고
    • Effect of atorvastatin on regional arterial stiffness in patients with type 2 diabetes mellitus
    • Shinohara K. Shoji T. Kimoto E. Yokoyama H. Fujiwara S. Hatsuda S. et al. (2005) Effect of atorvastatin on regional arterial stiffness in patients with type 2 diabetes mellitus. J Atheroscler Thromb 12: 205–210.
    • (2005) J Atheroscler Thromb , vol.12 , pp. 205-210
    • Shinohara, K.1    Shoji, T.2    Kimoto, E.3    Yokoyama, H.4    Fujiwara, S.5    Hatsuda, S.6
  • 36
    • 84858761210 scopus 로고    scopus 로고
    • Effective prevention of cardiovascular disease and diabetes-related events with atorvastatin in Japanese elderly patients with type 2 diabetes mellitus: adjusting for treatment changes using a marginal structural proportional hazards model and a rank-preserving structural failure time model
    • Shinozaki T. Matsuyama Y. Iimuro S. Umegaki H. Sakurai T. Araki A. et al. (2012) Effective prevention of cardiovascular disease and diabetes-related events with atorvastatin in Japanese elderly patients with type 2 diabetes mellitus: adjusting for treatment changes using a marginal structural proportional hazards model and a rank-preserving structural failure time model. Geriatr Gerontol Int 12(Suppl. 1): 88–102.
    • (2012) Geriatr Gerontol Int , vol.12 , pp. 88-102
    • Shinozaki, T.1    Matsuyama, Y.2    Iimuro, S.3    Umegaki, H.4    Sakurai, T.5    Araki, A.6
  • 37
    • 30344431522 scopus 로고    scopus 로고
    • Atorvastatin improves left ventricular systolic function and serum markers of inflammation in nonischemic heart failure
    • Sola S. Mir M. Lerakis S. Tandon N. Khan B. (2006) Atorvastatin improves left ventricular systolic function and serum markers of inflammation in nonischemic heart failure. J Am Coll Cardiol 47: 332–337.
    • (2006) J Am Coll Cardiol , vol.47 , pp. 332-337
    • Sola, S.1    Mir, M.2    Lerakis, S.3    Tandon, N.4    Khan, B.5
  • 38
    • 20344398940 scopus 로고    scopus 로고
    • Randomized trial of atorvastatin in improving endothelial function in diabetics without prior coronary disease and having average cholesterol level
    • Tantikosoom W. Thinkhamrop B. Kiatchusakul S. Jarernsiripornkul N. Srinakarin J. Ojongpian S. (2005) Randomized trial of atorvastatin in improving endothelial function in diabetics without prior coronary disease and having average cholesterol level. J Med Assoc Thai 88:399–406.
    • (2005) J Med Assoc Thai , vol.88 , pp. 399-406
    • Tantikosoom, W.1    Thinkhamrop, B.2    Kiatchusakul, S.3    Jarernsiripornkul, N.4    Srinakarin, J.5    Ojongpian, S.6
  • 39
    • 53049095795 scopus 로고    scopus 로고
    • Effect of rosuvastatin in patients with chronic heart failure (the GISSI–HF trial): a randomised, double-blind, placebo-controlled trial
    • Tavazzi L. Maggioni A. Marchioli R. Barlera S. Franzosi M. Latini R. et al. (2008) Effect of rosuvastatin in patients with chronic heart failure (the GISSI–HF trial): a randomised, double-blind, placebo-controlled trial. Lancet 372: 1231–1239.
    • (2008) Lancet , vol.372 , pp. 1231-1239
    • Tavazzi, L.1    Maggioni, A.2    Marchioli, R.3    Barlera, S.4    Franzosi, M.5    Latini, R.6
  • 41
    • 34547688762 scopus 로고    scopus 로고
    • Anti–inflammatory effects of atorvastatin improve left ventricular function in experimental diabetic cardiomyopathy
    • van Linthout S. Riad A. Dhayat N. Spillmann F. Du J. Dhayat S. et al. (2007) Anti–inflammatory effects of atorvastatin improve left ventricular function in experimental diabetic cardiomyopathy. Diabetologia 50: 1977–1986.
    • (2007) Diabetologia , vol.50 , pp. 1977-1986
    • van Linthout, S.1    Riad, A.2    Dhayat, N.3    Spillmann, F.4    Du, J.5    Dhayat, S.6
  • 42
    • 0035569562 scopus 로고    scopus 로고
    • HMG-CoA reductase inhibitors improve endothelial dysfunction in normocholesterolemic hypertension via reduced production of reactive oxygen species
    • Wassmann S. Laufs U. Bäumer A. Müller K. Ahlbory K. Linz W. et al. (2001) HMG-CoA reductase inhibitors improve endothelial dysfunction in normocholesterolemic hypertension via reduced production of reactive oxygen species. Hypertension 37: 1450–1457.
    • (2001) Hypertension , vol.37 , pp. 1450-1457
    • Wassmann, S.1    Laufs, U.2    Bäumer, A.3    Müller, K.4    Ahlbory, K.5    Linz, W.6
  • 44
    • 40949122403 scopus 로고    scopus 로고
    • Mechanisms underlying recoupling of eNOS by HMG-CoA reductase inhibition in a rat model of streptozotocin-induced diabetes mellitus
    • Wenzel P. Daiber A. Oelze M. Brandt M. Closs E. Xu J. et al. (2008) Mechanisms underlying recoupling of eNOS by HMG-CoA reductase inhibition in a rat model of streptozotocin-induced diabetes mellitus. Atherosclerosis 198: 65–76.
    • (2008) Atherosclerosis , vol.198 , pp. 65-76
    • Wenzel, P.1    Daiber, A.2    Oelze, M.3    Brandt, M.4    Closs, E.5    Xu, J.6
  • 45
    • 77950339319 scopus 로고    scopus 로고
    • Statin therapy shortens QTc, QTcd, and improves cardiac function in patients with chronic heart failure
    • Xie R. Cui W. Liu F. Yang C. Pei W. Lu J. et al. (2010) Statin therapy shortens QTc, QTcd, and improves cardiac function in patients with chronic heart failure. Int J Cardiol 140: 255–257.
    • (2010) Int J Cardiol , vol.140 , pp. 255-257
    • Xie, R.1    Cui, W.2    Liu, F.3    Yang, C.4    Pei, W.5    Lu, J.6
  • 46
    • 34249311583 scopus 로고    scopus 로고
    • Long-term effect of atorvastatin on neurohumoral activation and cardiac function in patients with chronic heart failure: a prospective randomized controlled study
    • Yamada T. Node K. Mine T. Morita T. Kioka H. Tsukamoto Y. et al. (2007) Long-term effect of atorvastatin on neurohumoral activation and cardiac function in patients with chronic heart failure: a prospective randomized controlled study. Am Heart J 153: 1055.e1–1055.e8
    • (2007) Am Heart J , vol.153 , pp. 1055.e1-1055.e8
    • Yamada, T.1    Node, K.2    Mine, T.3    Morita, T.4    Kioka, H.5    Tsukamoto, Y.6
  • 47
    • 21044443182 scopus 로고    scopus 로고
    • Diabetic vascular complications: pathophysiology, biochemical basis and potential therapeutic strategy
    • Yamagishi S. Imaizumi T. (2005) Diabetic vascular complications: pathophysiology, biochemical basis and potential therapeutic strategy. Curr Phar Des 11: 2279–2299.
    • (2005) Curr Phar Des , vol.11 , pp. 2279-2299
    • Yamagishi, S.1    Imaizumi, T.2
  • 48
    • 33745069673 scopus 로고    scopus 로고
    • Atorvastatin and diabetic vascular complications
    • Yamagishi S. Matsui T. Nakamura K. (2006) Atorvastatin and diabetic vascular complications. Curr Pharm Des 12 :1549–1554.
    • (2006) Curr Pharm Des , vol.12 , pp. 1549-1554
    • Yamagishi, S.1    Matsui, T.2    Nakamura, K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.