Atorvastatin increases oxidative stress and modulates angiogenesis in Ossabaw swine with the metabolic syndrome

Journal of Thoracic and Cardiovascular Surgery

Volumn 144, Issue 6, 2012, Pages 1486-1493

  Elmadhun, Nassrene Y ^a   Lassaletta, Antonio D ^a   Chu, Louis M ^a   Liu, Yuhong ^a   Feng, Jun ^a   Sellke, Frank W ^a  

^a BROWN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE DIPHOSPHATE; ADENOSINE PHOSPHATE; ATORVASTATIN; COPPER ZINC SUPEROXIDE DISMUTASE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; EXTRACELLULAR SUPEROXIDE DISMUTASE; MANGANESE SUPEROXIDE DISMUTASE; MITOGEN ACTIVATED PROTEIN KINASE; MYELOPEROXIDASE; NITROPRUSSIDE SODIUM; RAC1 PROTEIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2; VASCULOTROPIN;

ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERY CONSTRICTION; ARTICLE; CHRONIC DISEASE; CONTROLLED STUDY; DOSE RESPONSE; HEART MUSCLE ISCHEMIA; HEART MUSCLE PERFUSION; HEART PACING; LIPID DIET; LIPID PEROXIDATION; MALE; METABOLIC SYNDROME X; MICROVASCULATURE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REST; SWINE; UPREGULATION;

ANGIOGENESIS INDUCING AGENTS; ANGIOGENIC PROTEINS; ANIMALS; BIOLOGICAL MARKERS; COLLATERAL CIRCULATION; CORONARY CIRCULATION; DIET, HIGH-FAT; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; FIBROSIS; HEPTANOIC ACIDS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; LIPID PEROXIDATION; MALE; METABOLIC SYNDROME X; MICROVESSELS; MYOCARDIAL ISCHEMIA; MYOCARDIAL PERFUSION IMAGING; MYOCARDIUM; NEOVASCULARIZATION, PHYSIOLOGIC; OXIDATIVE STRESS; PYRROLES; SIGNAL TRANSDUCTION; SWINE; SWINE, MINIATURE; VASODILATION; VASODILATOR AGENTS;

EID: 84869096206     PISSN: 00225223     EISSN: 1097685X     Source Type: Journal    
DOI: 10.1016/j.jtcvs.2012.08.065     Document Type: Article

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