1,3-dipolar cycloadditions of ethyl 2-diazo-3,3,3-trifluoropropanoate to alkynes and [1,5] sigmatropic rearrangements of the resulting 3H-pyrazoles: Synthesis of mono-, bis- and tris(trifluoromethyl)-substituted pyrazoles

Helvetica Chimica Acta

Volumn 97, Issue 6, 2014, Pages 808-821

  Gladow, Daniel ^a   Doniz Kettenmann, Sebastian ^a   Reissig, Hans Ulrich ^a  

^a FREIE UNIVERSITÄT BERLIN   (Germany)

Author keywords

1,3 Dipolar cycloaddition; Alkanes, diazo; Cycloadditions; Fluorinated heterocycles; Pyrazoles, trifluoromethyl substituted; 1,5 Sigmatropic rearrangement

Indexed keywords

CYCLOADDITION; ELECTRONS; HYDROCARBONS;

1 ,3-DIPOLARCYCLOADDITION; CYCLOADDITIONS; HETEROCYCLES; PYRAZOLES; SIGMATROPIC REARRANGEMENTS;

ORGANIC POLYMERS;

3H PYRAZOLE DERIVATIVE; ACETYLENEDICARBOXYLIC ACID DIMETHYL ESTER; ALKANE DERIVATIVE; ALKENE; ALKYNE; CELECOXIB; DIAZOALKANE; DIPHENYLACETYLENE; ETHYL 2 DIAZO 3,3,3 TRIFLUOROPROPANOATE; PHENYLACETYLENE; PYRAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CHEMICAL REACTION; CYCLOADDITION; DIASTEREOISOMER; DIPOLE; DRUG SYNTHESIS; ELECTRON; ELECTROSPRAY MASS SPECTROMETRY; FLUORINE NUCLEAR MAGNETIC RESONANCE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HIGH TEMPERATURE; PRIORITY JOURNAL;

EID: 84902475850     PISSN: 0018019X     EISSN: 15222675     Source Type: Journal    
DOI: 10.1002/hlca.201400032     Document Type: Article

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