Alkylation and ring opening of perfluoroalkyl- and perfluoroaryl- substituted 2-siloxycyclopropanecarboxylates yielding fluorinated γ-oxo esters or β,γ-unsaturated ketones

Synthesis (Germany)

Volumn 45, Issue 15, 2013, Pages 2179-2187

  Gladow, Daniel ^a   Reissig, Hans Ulrich ^a  

^a FREIE UNIVERSITÄT BERLIN   (Germany)

Author keywords

oxo esters; defluorination; donor acceptor cyclopropanes; fluorine; ring opening

Indexed keywords

ALKYL HALIDES; DEFLUORINATION; DIASTEREOSELECTIVITIES; DONOR-ACCEPTOR CYCLOPROPANES; GRIGNARD REAGENT; RING OPENING; TRIETHYLAMINES; UNSATURATED KETONES;

ESTERS; FLUORINE; KETONES; PROPANE;

ESTERIFICATION;

1 (PERFLUOROPHENYL) 4,4 DIPHENYLBUT 3 EN 1 ONE; 1,1,1 TRIFLUORO 5,5 DIPHENYLPENT 4 EN 2 ONE; 1,1,1 TRIFLUORO 5,5 DIPHENYLPENTAN 2 ONE; 4 METHYL 1 (PERFLUOROPHENYL)PENT 3 EN 1 ONE; 5 METHOXY 3 (TRIMETHOXYMETHYL)DIHYDROFURAN 2 (3H) ONE; BETA GAMMA UNSATURATED KETONE; CARBOXYLIC ACID DERIVATIVE; CYCLOPROPANE DERIVATIVE; ETHYL 4 OXO 2 (TRIFLUOROMETHYL)BUTANOIC ACID; ETHYL 5,5,5 TRIFLUORO 4 OXO 2 (TRIFLUOROMETHYL)PENTANOIC ACID; ETHYL 5,5,6,6,7,7,8,8,9,9,9 UNDECAFLUORO 4 OXO 2 (TRIFLUOROMETHYL)NONANOIC ACID; FLUORINE; GRIGNARD REAGENT; KETONE DERIVATIVE; METHYL 1 ALLYL 2 (TRIFLUOROMETHYL) 2 (TRIMETHYLSILOXY)CYCLOPROPANECARBOXYLIC ACID; METHYL 1 METHYL 2 (PERFLUOROPENTYL) 2 (TRIMETHYLSILOXY)CYCLOPROPANECARBOXYLIC ACID; METHYL 1 METHYL 2 (PERFLUOROPHENYL) 2 (TRIMETHYLSILOXY)CYCLOPROPANECARBOXYLIC ACID; METHYL 1 METHYL 2 (TRIFLUOROMETHYL) 2 (TRIMETHYLSILOXY)CYCLOPROPANECARBOXYLIC ACID; METHYL 2 (3,3,3 TRIFLUORO 2 OXOPROPYL)PENT 4 ENOATE; METHYL 2 [2 OXO 2 (PERFLUOROPHENYL)ETHYL]PENT 4 ENOATE; METHYL 4 OXO 4 (PERFLUOROPHENYL)BUTANOIC ACID; METHYL 5 METHOXY 2 OXOTETRAHYDROFURAN 3 CARBOXYLIC ACID; METHYL 5,5,5 TRIFLUORO 2 METHYL 4 OXOPENTANOIC ACID; METHYL 5,5,5 TRIFLUORO 4 OXOPENTANOIC ACID; METHYL 5,5,6,6,7,7,8,8,9,9,9 UNDECAFLUORO 2 METHYL 4 OXONONANOIC ACID; METHYL 5,5,6,6,7,7,8,8,9,9,9 UNDECAFLUORO 4 OXONONANOIC ACID; PERFLUOROALKYL 2 SILOXYCYCLOPROPANECARBOXYLIC ACID; PERFLUOROARYL 2 SILOXYCYCLOPROPANECARBOXYLIC ACID; UNCLASSIFIED DRUG;

ALKYLATION; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CHEMICAL REACTION; CHEMICAL STRUCTURE; DEFLUORINATION; DESILYLATION; FLUORINE NUCLEAR MAGNETIC RESONANCE; NUCLEOPHILICITY; PROTON NUCLEAR MAGNETIC RESONANCE; PROTON TRANSPORT; RING OPENING; STEREOCHEMISTRY;

EID: 84880922735     PISSN: 00397881     EISSN: 1437210X     Source Type: Journal    
DOI: 10.1055/s-0033-1338892     Document Type: Article

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