Elucidating the role of disulfide bond on amyloid formation and fibril reversibility of somatostatin-14: Relevance to its storage and secretion

Journal of Biological Chemistry

Volumn 289, Issue 24, 2014, Pages 16884-16903

  Anoop, Arunagiri ^a   Ranganathan, Srivastav ^a   Dhaked, Bhagwan Das ^a   Jha, Narendra Nath ^a   Pratihar, Supriya ^b   Ghosh, Saikat ^a   Sahay, Shruti ^a   Kumar, Santosh ^c   Das, Subhadeep ^a   Kombrabail, Mamata ^b   Agarwal, Kumud ^a   Jacob, Reeba S ^a   Singru, Praful ^c   Bhaumik, Prasenjit ^a   Padinhateeri, Ranjith ^a   Kumar, Ashutosh ^a   Maji, Samir K ^a  

^a INDIAN INSTITUTE OF TECHNOLOGY BOMBAY   (India)

^b TATA INSTITUTE OF FUNDAMENTAL RESEARCH   (India)

^c NATIONAL INSTITUTE OF SCIENCE EDUCATION AND RESEARCH   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ASSOCIATION REACTIONS; CONFORMATIONS; COVALENT BONDS; DYNAMICS; ENDOCRINOLOGY; GLYCOPROTEINS; HORMONES; MAMMALS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; SULFUR COMPOUNDS;

CONFORMATIONAL DYNAMICS; CONFORMATIONAL FLEXIBILITY; DENATURING CONDITIONS; INITIAL STRUCTURES; INTERMOLECULAR INTERACTIONS; REVERSIBLE STORAGE; SUBCELLULAR COMPARTMENTS; TWO-DIMENSIONAL NMR;

PEPTIDES;

AMYLOID; CYSTEINE; MONOMER; SOMATOSTATIN; SOMATOSTATIN 14;

ARTICLE; BIOGENESIS; DISULFIDE BOND; FIBER; IN VITRO STUDY; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN CLEAVAGE; PROTEIN CONFORMATION; PROTEIN FUNCTION; PROTEIN SECRETION; PROTEIN STRUCTURE;

AMYLOID; DISULFIDE; PEPTIDE HORMONE; PROTEIN AGGREGATION; PROTEIN SECRETION;

AMINO ACID SEQUENCE; AMYLOID; ANIMALS; DISULFIDES; EXOCYTOSIS; HYPOTHALAMUS; MOLECULAR DYNAMICS SIMULATION; MOLECULAR SEQUENCE DATA; POLYMERIZATION; PROTEIN CONFORMATION; RATS; SECRETORY VESICLES; SOMATOSTATIN;

EID: 84902440214     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.548354     Document Type: Article

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