-
1
-
-
0037077040
-
Toxic proteins in neurode-generative disease
-
Taylor, J. P., Hardy, J., and Fischbeck, K. H. (2002) Toxic proteins in neurode-generative disease. Science 296, 1991-1995.
-
(2002)
Science
, vol.296
, pp. 1991-1995
-
-
Taylor, J.P.1
Hardy, J.2
Fischbeck, K.H.3
-
2
-
-
0347987853
-
Folding proteins in fatal ways
-
Selkoe, D. J. (2003) Folding proteins in fatal ways. Nature 426, 900-904.
-
(2003)
Nature
, vol.426
, pp. 900-904
-
-
Selkoe, D.J.1
-
4
-
-
0035140975
-
Going new places using an old MAP: Tau, microtubules and human neurodegenerative disease
-
Garcia, M. L. and Cleveland, D. W. (2001) Going new places using an old MAP: tau, microtubules and human neurodegenerative disease. Curr. Opin. Cell Biol. 13, 41-48.
-
(2001)
Curr. Opin. Cell Biol
, vol.13
, pp. 41-48
-
-
Garcia, M.L.1
Cleveland, D.W.2
-
5
-
-
0002792366
-
Cloning and sequencing of the cDNA encoding a core protein of the paired helical filament of Alzheimer disease: Identification as the microtubule-associated protein tau
-
Goedert, M., Wischik, C. M., Crowther, R. A., Walker, J. E., and Klug, A. (1988) Cloning and sequencing of the cDNA encoding a core protein of the paired helical filament of Alzheimer disease: identification as the microtubule-associated protein tau. Proc. Natl. Acad. Sci. USA 85, 4051-4055.
-
(1988)
Proc. Natl. Acad. Sci. USA
, vol.85
, pp. 4051-4055
-
-
Goedert, M.1
Wischik, C.M.2
Crowther, R.A.3
Walker, J.E.4
Klug, A.5
-
6
-
-
0034530634
-
Molecular genetics of chromosome 17 tauopathies
-
Hutton, M. (2000) Molecular genetics of chromosome 17 tauopathies. Ann. NY Acad. Sci. 920, 63-73.
-
(2000)
Ann. NY Acad. Sci
, vol.920
, pp. 63-73
-
-
Hutton, M.1
-
7
-
-
0034528413
-
Tau gene mutations in frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17). Their relevance for understanding the neurogenerative process
-
Goedert, M., Ghetti, B., and Spillantini, M. G. (2000) Tau gene mutations in frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17). Their relevance for understanding the neurogenerative process. Ann. NY Acad. Sci. 920, 74-83.
-
(2000)
Ann. NY Acad. Sci
, vol.920
, pp. 74-83
-
-
Goedert, M.1
Ghetti, B.2
Spillantini, M.G.3
-
8
-
-
0015408029
-
The relation of the properties of Congo red-stained amyloid fibrils to the β-conformation
-
Glenner, G. G., Eanes, E. D., and Page, D. L. (1972) The relation of the properties of Congo red-stained amyloid fibrils to the β-conformation. J. Histochem. Cytochem. 20, 821-826.
-
(1972)
J. Histochem. Cytochem
, vol.20
, pp. 821-826
-
-
Glenner, G.G.1
Eanes, E.D.2
Page, D.L.3
-
9
-
-
0026528990
-
A comparative study of histological and immunohistochemical methods for neurofibrillary tangles and senile plaques in Alzheimer's disease
-
CrossRefGoogle Scholar
-
Vallet, P. G., Guntern, R., Hof, P. R., et al. (1992) A comparative study of histological and immunohistochemical methods for neurofibrillary tangles and senile plaques in Alzheimer's disease. Acta Neuropathol. (Berl) 83, 170-178. CrossRefGoogle Scholar
-
(1992)
Acta Neuropathol
, vol.83
, pp. 170-178
-
-
Vallet, P.G.1
Guntern, R.2
Hof, P.R.3
-
10
-
-
0027502784
-
Thioflavine T interaction with synthetic Alzheimer's disease beta-amyloid peptides: Detection of amyloid aggregation in solution
-
LeVine, H. (1993) Thioflavine T interaction with synthetic Alzheimer's disease beta-amyloid peptides: detection of amyloid aggregation in solution. Protein Sci. 2, 404-410.
-
(1993)
Protein Sci
, vol.2
, pp. 404-410
-
-
Levine, H.1
-
11
-
-
0033849738
-
Review: History of the amyloid fibril
-
Sipe, J. D. and Cohen, A. S. (2000) Review: history of the amyloid fibril. J. Struct. Biol. 130, 88-98.
-
(2000)
J. Struct. Biol
, vol.130
, pp. 88-98
-
-
Sipe, J.D.1
Cohen, A.S.2
-
12
-
-
0033865051
-
Twist and sheet: Variations on the theme of amyloid
-
Kirschner, D. A., Teplow, D. B., and Damas, A. M. (2000) Twist and sheet: variations on the theme of amyloid. J. Struct. Biol. 130, 87.
-
(2000)
J. Struct. Biol
, vol.130
, pp. 87
-
-
Kirschner, D.A.1
Teplow, D.B.2
Damas, A.M.3
-
13
-
-
0034718206
-
Approaches to discovery and characterization of inhibitors of amyloid beta-peptide polymerization
-
Findeis, M. A. (2000) Approaches to discovery and characterization of inhibitors of amyloid beta-peptide polymerization. Biochim. Biophys. Acta 1502, 76-84.
-
(2000)
Biochim. Biophys. Acta
, vol.1502
, pp. 76-84
-
-
Findeis, M.A.1
-
14
-
-
0034695631
-
Controlling polymerization of beta-amyloid and prion-derived peptides with synthetic small molecule ligands
-
Kuner, P., Bohrmann, B., Tjernberg, L. O., et al. (2000) Controlling polymerization of beta-amyloid and prion-derived peptides with synthetic small molecule ligands. J. Biol. Chem. 275, 1673-1678.
-
(2000)
J. Biol. Chem
, vol.275
, pp. 1673-1678
-
-
Kuner, P.1
Bohrmann, B.2
Tjernberg, L.O.3
-
15
-
-
0024371547
-
Alzheimer's disease: Mismatch between amyloid plaques and neuritic plaques
-
Braak, H., Braak, E., Ohm, T., and Bohl, J. (1989) Alzheimer's disease: mismatch between amyloid plaques and neuritic plaques. Neurosci. Lett. 103, 24-28.
-
(1989)
Neurosci. Lett
, vol.103
, pp. 24-28
-
-
Braak, H.1
Braak, E.2
Ohm, T.3
Bohl, J.4
-
16
-
-
0032516493
-
Rapid assembly of Alzheimer-like paired helical filaments from microtubule-associated protein tau monitored by fluorescence in solution
-
Friedhoff, P., Schneider, A., Mandelkow, E. M., and Mandelkow, E. (1998) Rapid assembly of Alzheimer-like paired helical filaments from microtubule-associated protein tau monitored by fluorescence in solution. Biochemistry 37, 10223-10230.
-
(1998)
Biochemistry
, vol.37
, pp. 10223-10230
-
-
Friedhoff, P.1
Schneider, A.2
Mandelkow, E.M.3
Mandelkow, E.4
-
17
-
-
0034625060
-
Assembly of tau protein into Alzheimer paired helical filaments depends on a local sequence motif ((306)VQIVYK(311)) forming beta structure
-
von Bergen, M., Friedhoff, P., Biernat, J., Heberle, J., Mandelkow, E. M., and Mandelkow, E. (2000) Assembly of tau protein into Alzheimer paired helical filaments depends on a local sequence motif ((306)VQIVYK(311)) forming beta structure. Proc. Natl. Acad. Sci. USA 97, 5129-5134.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 5129-5134
-
-
Von Bergen, M.1
Friedhoff, P.2
Biernat, J.3
Heberle, J.4
Mandelkow, E.M.5
Mandelkow, E.6
-
18
-
-
0032428153
-
A nucleated assembly mechanism of Alzheimer paired helical filaments
-
CrossRefGoogle Scholar
-
Friedhoff, P., von Bergen, M., Mandelkow, E. M., and Mandelkow, E. (1998) A nucleated assembly mechanism of Alzheimer paired helical filaments. Natl. Acad. Sci. USA 95, 15712-15717. CrossRefGoogle Scholar
-
(1998)
Natl. Acad. Sci. USA
, vol.95
, pp. 15712-15717
-
-
Friedhoff, P.1
Von Bergen, M.2
Mandelkow, E.M.3
Mandelkow, E.4
-
19
-
-
0026551711
-
The switch of tau protein to an Alzheimer-like state includes the phosphorylation of two serine-proline motifs upstream of the microtubule binding region
-
Biernat, J., Mandelkow, E. M., Schröter, C., et al. (1992) The switch of tau protein to an Alzheimer-like state includes the phosphorylation of two serine-proline motifs upstream of the microtubule binding region. EMBO J. 11, 1593-1597.
-
(1992)
EMBO J
, vol.11
, pp. 1593-1597
-
-
Biernat, J.1
Mandelkow, E.M.2
Schröter, C.3
-
20
-
-
0034718571
-
Structure, microtubule interactions, and paired helical filament aggregation by tau mutants of frontotemporal dementias
-
Barghorn, S., Zheng-Fischhofer, Q., Ackmann, M., Biernat, J., von Bergen, M., and Mandelkow, E. (2000) Structure, microtubule interactions, and paired helical filament aggregation by tau mutants of frontotemporal dementias. Biochemistry 39, 11714-11721.
-
(2000)
Biochemistry
, vol.39
, pp. 11714-11721
-
-
Barghorn, S.1
Zheng-Fischhofer, Q.2
Ackmann, M.3
Biernat, J.4
Von Bergen, M.5
Mandelkow, E.6
-
21
-
-
0027958069
-
The use of fluorescence methods to monitor unfolding transitions in proteins
-
Eftink, M. R. (1994) The use of fluorescence methods to monitor unfolding transitions in proteins. Biophys. J. 66, 482-501.
-
(1994)
Biophys. J
, vol.66
, pp. 482-501
-
-
Eftink, M.R.1
-
22
-
-
0036830506
-
Structure, stability, and aggregation of paired helical filaments from tau protein and FTDP-17 mutants probed by tryptophan scanning mutagenesis
-
Li, L., von Bergen, M., Mandelkow, E. M., and Mandelkow, E. (2002) Structure, stability, and aggregation of paired helical filaments from tau protein and FTDP-17 mutants probed by tryptophan scanning mutagenesis. J. Biol. Chem. 277,41390-41400.
-
(2002)
J. Biol. Chem
, vol.277
, pp. 41390-41400
-
-
Li, L.1
Von Bergen, M.2
Mandelkow, E.M.3
Mandelkow, E.4
-
23
-
-
0035930625
-
Mutations of tau protein in frontotemporal dementia promote aggregation of paired helical filaments by enhancing local beta-structure
-
von Bergen, M., Barghorn, S., Li, L., Marx, A., Biernat, J., Mandelkow, E. M., and Mandelkow, E. (2001) Mutations of tau protein in frontotemporal dementia promote aggregation of paired helical filaments by enhancing local beta-structure. J. Biol. Chem. 276,48165-48174
-
(2001)
J. Biol. Chem
, vol.276
, pp. 48165-48174
-
-
Von Bergen, M.1
Barghorn, S.2
Li, L.3
Marx, A.4
Biernat, J.5
Mandelkow, E.M.6
Mandelkow, E.7
|