-
2
-
-
12344274317
-
Somatostatin receptor 1 selective analogues: 3. Dicyclic peptides
-
Rivier, J.; Kirby, D.; Erchegyi, J.; Waser, B.; Eltschinger, V.; et al. Somatostatin receptor 1 selective analogues: 3. Dicyclic peptides. J. Med. Chem. 2005, 48, 515-522.
-
(2005)
J. Med. Chem.
, vol.48
, pp. 515-522
-
-
Rivier, J.1
Kirby, D.2
Erchegyi, J.3
Waser, B.4
Eltschinger, V.5
-
3
-
-
0021105680
-
Somatostatin
-
Reichlin, S. Somatostatin. N. Engl. J. Med. 1983, 309, 1495-1501.
-
(1983)
N. Engl. J. Med.
, vol.309
, pp. 1495-1501
-
-
Reichlin, S.1
-
4
-
-
0021019016
-
Somatostatin (second of two parts)
-
Reichlin, S. Somatostatin (second of two parts). N. Engl. J. Med. 1983, 309, 1556-1563.
-
(1983)
N. Engl. J. Med.
, vol.309
, pp. 1556-1563
-
-
Reichlin, S.1
-
5
-
-
0020524081
-
Effects of somatostatin on mammalian cortical neurons in culture: Physiological actions and unusual dose response characteristics
-
Delfs, J. R.; Dichter, M. A. Effects of somatostatin on mammalian cortical neurons in culture: physiological actions and unusual dose response characteristics. J. Neurosci. 1983, 3, 1176-1188.
-
(1983)
J. Neurosci.
, vol.3
, pp. 1176-1188
-
-
Delfs, J.R.1
Dichter, M.A.2
-
6
-
-
0020644949
-
Nonopioid neuropeptides in mammalian CNS
-
Iversen, L. L. Nonopioid neuropeptides in mammalian CNS. Annu. Rev. Pharmacol. Toxicol. 1983, 23, 1-27.
-
(1983)
Annu. Rev. Pharmacol. Toxicol.
, vol.23
, pp. 1-27
-
-
Iversen, L.L.1
-
8
-
-
10744223244
-
4-selective somatostatin (SRIF) agonists. Part II: Analogues with β-methyl-3-(2-naphthyl)-alanine substitutions at position 8
-
4-selective somatostatin (SRIF) agonists. Part II: Analogues with β-methyl-3-(2-naphthyl)-alanine substitutions at position 8. J. Med. Chem. 2003, 46, 5587-5596.
-
(2003)
J. Med. Chem.
, vol.46
, pp. 5587-5596
-
-
Erchegyi, J.1
Penke, B.2
Simon, L.3
Michaelson, S.4
Wenger, S.5
-
10
-
-
0038440483
-
A novel somatostatin mimic with broad somatotropin release inhibitory factor receptor binding and superior therapeutic potential
-
Lewis, I.; Bauer, W.; Albert, R.; Chandramouli, N.; Pless, J. et al. A novel somatostatin mimic with broad somatotropin release inhibitory factor receptor binding and superior therapeutic potential. J. Med. Chem. 2003, 46, 2334-2344.
-
(2003)
J. Med. Chem.
, vol.46
, pp. 2334-2344
-
-
Lewis, I.1
Bauer, W.2
Albert, R.3
Chandramouli, N.4
Pless, J.5
-
11
-
-
0037027926
-
A new peptidic somatostatin agonist with high affinity to all five somatostatin receptors
-
Reubi, J. C.; Eisenwiener, K. P.; Rink, H.; Waser, B.; Macke, H. R. A new peptidic somatostatin agonist with high affinity to all five somatostatin receptors. Eur. J. Pharmacol. 2002, 456, 45-49.
-
(2002)
Eur. J. Pharmacol.
, vol.456
, pp. 45-49
-
-
Reubi, J.C.1
Eisenwiener, K.P.2
Rink, H.3
Waser, B.4
Macke, H.R.5
-
12
-
-
0034905424
-
Review: Somatostatin analogs
-
Janecka, A.; Zubrzycka, M.; Janecki, T. Review: Somatostatin analogs. J. Pept. Res. 2001, 58, 91-107.
-
(2001)
J. Pept. Res.
, vol.58
, pp. 91-107
-
-
Janecka, A.1
Zubrzycka, M.2
Janecki, T.3
-
13
-
-
0035927432
-
Potent somatostatin undecapeptide agonists selective for somatostatin receptor 1 (sst1)
-
Rivier, J. E.; Hoeger, C.; Erchegyi, J.; Gulyas, J.; DeBoard, R. et al. Potent somatostatin undecapeptide agonists selective for somatostatin receptor 1 (sst1). J. Med. Chem. 2001, 44, 2238-2246.
-
(2001)
J. Med. Chem.
, vol.44
, pp. 2238-2246
-
-
Rivier, J.E.1
Hoeger, C.2
Erchegyi, J.3
Gulyas, J.4
DeBoard, R.5
-
14
-
-
0034610363
-
SST3-selective potent peptidic somatostatin receptor antagonists
-
Reubi, J. C.; Schaer, J.-C.; Wenger, S.; Hoeger, C.; Erchegyi, J. et al. SST3-selective potent peptidic somatostatin receptor antagonists. Proc. Natl. Acad. Sci. U.S.A. 2000, 97, 13973-13978.
-
(2000)
Proc. Natl. Acad. Sci. U.S.A.
, vol.97
, pp. 13973-13978
-
-
Reubi, J.C.1
Schaer, J.-C.2
Wenger, S.3
Hoeger, C.4
Erchegyi, J.5
-
15
-
-
0017326457
-
Pharmacology of TRF, LRF and somatostatin
-
Plenum Press: New York
-
Vale, W.; Rivier, C.; Brown, M.; Rivier, J. Pharmacology of TRF, LRF and somatostatin. Hypothalamic Peptide Hormones and Pituitary Regulation: Advances in Experimental Medicine and Biology; Plenum Press: New York, 1977; pp 123-156.
-
(1977)
Hypothalamic Peptide Hormones and Pituitary Regulation: Advances in Experimental Medicine and Biology
, pp. 123-156
-
-
Vale, W.1
Rivier, C.2
Brown, M.3
Rivier, J.4
-
16
-
-
0018073512
-
Biologic and immunologic activities and applications of somatostatin analogs
-
Vale, W.; Rivier, J.; Ling, N.; Brown, M. Biologic and immunologic activities and applications of somatostatin analogs. Metabolism 1978, 27, 1391-1401.
-
(1978)
Metabolism
, vol.27
, pp. 1391-1401
-
-
Vale, W.1
Rivier, J.2
Ling, N.3
Brown, M.4
-
17
-
-
0019862208
-
A potent cyclic hexapeptide analogue of somatostatin
-
Veber, D. F.; Freidinger, R. M.; Perlow, D. S.; Paleveda, W. J., Jr.; Holly, F. W. et al. A potent cyclic hexapeptide analogue of somatostatin. Nature 1981, 292, 55-58.
-
(1981)
Nature
, vol.292
, pp. 55-58
-
-
Veber, D.F.1
Freidinger, R.M.2
Perlow, D.S.3
Paleveda Jr., W.J.4
Holly, F.W.5
-
18
-
-
0029137991
-
Structure of octreotide, a somatostatin analogue
-
Pohl, E.; Heine, A.; Sheldrick, G. M.; Dauter, Z.; Wilson, K. S. et al. Structure of octreotide, a somatostatin analogue. Acta Crystallogr. 1995, D51, 48-59.
-
(1995)
Acta Crystallogr.
, vol.D51
, pp. 48-59
-
-
Pohl, E.1
Heine, A.2
Sheldrick, G.M.3
Dauter, Z.4
Wilson, K.S.5
-
19
-
-
0002649780
-
Design and discovery in the development of peptide analogs
-
Peptides: Chemistry and Biology: Cambridge, MA, June 16-21
-
Veber, D. F. Design and discovery in the development of peptide analogs. Twelfth American Peptide Symposium; Peptides: Chemistry and Biology: Cambridge, MA, June 16-21, 1991; pp 1-14.
-
(1991)
Twelfth American Peptide Symposium
, pp. 1-14
-
-
Veber, D.F.1
-
20
-
-
18044405028
-
A bicyclic and hsst2 selective somatostatin analogue: Design, synthesis, conformational analysis and binding
-
Falb, E.; Salitra, Y.; Yechezkel, T.; Bracha, M.; Litman, P. et al. A bicyclic and hsst2 selective somatostatin analogue: design, synthesis, conformational analysis and binding. Bioorg. Med. Chem. 2001, 9, 3255-3264.
-
(2001)
Bioorg. Med. Chem.
, vol.9
, pp. 3255-3264
-
-
Falb, E.1
Salitra, Y.2
Yechezkel, T.3
Bracha, M.4
Litman, P.5
-
21
-
-
0034772029
-
A bioactive somatostatin analogue without a type II′ beta-turn: Synthesis and conformational analysis in solution
-
Jiang, S.; Gazal, S.; Gelerman, G.; Ziv, O.; Karpov, O. et al. A bioactive somatostatin analogue without a type II′ beta-turn: synthesis and conformational analysis in solution. J. Pept. Sci. 2001, 7, 521-528.
-
(2001)
J. Pept. Sci.
, vol.7
, pp. 521-528
-
-
Jiang, S.1
Gazal, S.2
Gelerman, G.3
Ziv, O.4
Karpov, O.5
-
22
-
-
0034624210
-
Synthesis, biological activities and conformational studies of somatostatin analogues
-
Nattern, R.-H.; Moore, S. B.; Tran, T.-A.; Rueter, J. K.; Goodman, M. Synthesis, biological activities and conformational studies of somatostatin analogues. Tetrahedron 2000, 56, 9819-9831.
-
(2000)
Tetrahedron
, vol.56
, pp. 9819-9831
-
-
Nattern, R.-H.1
Moore, S.B.2
Tran, T.-A.3
Rueter, J.K.4
Goodman, M.5
-
24
-
-
0002404299
-
Design and synthesis of a peptidomimetic employing β-D-glucose for scaffolding
-
ESCOM Science Publishers B. V.: Leiden, The Netherlands
-
Nicolaou, K. C.; Salvino, J. M.; Raynor, K.; Pietranico, S.; Reisine, T. et al. Design and synthesis of a peptidomimetic employing β-D-glucose for scaffolding. Peptides - Chemistry, Structure and Biology; ESCOM Science Publishers B. V.: Leiden, The Netherlands, 1990; pp 881-884.
-
(1990)
Peptides - Chemistry, Structure and Biology
, pp. 881-884
-
-
Nicolaou, K.C.1
Salvino, J.M.2
Raynor, K.3
Pietranico, S.4
Reisine, T.5
-
25
-
-
0031576336
-
Torsion angle dynamics for NMR structure calculation with the new program DYANA
-
Güntert, P.; Mumenthaler, C.; Wüthrich, K. Torsion angle dynamics for NMR structure calculation with the new program DYANA. J. Mol. Biol. 1997, 273, 283-298.
-
(1997)
J. Mol. Biol.
, vol.273
, pp. 283-298
-
-
Güntert, P.1
Mumenthaler, C.2
Wüthrich, K.3
-
26
-
-
0021905444
-
Dynamics and conformational energetics of a peptide hormone: Vasopressin
-
Hagler, A. T.; Dauber, P.; Osguthorpe, D. J.; Hempel, J. C. Dynamics and conformational energetics of a peptide hormone: vasopressin. Science 1985, 227, 1309-1315.
-
(1985)
Science
, vol.227
, pp. 1309-1315
-
-
Hagler, A.T.1
Dauber, P.2
Osguthorpe, D.J.3
Hempel, J.C.4
-
27
-
-
0031028837
-
Multiconformational NMR analysis of sandostatin (octreotide): Equilibrium between β-sheet and partially helical structures
-
Melacini, G.; Zhu, Q.; Goodman, M. Multiconformational NMR analysis of sandostatin (octreotide): Equilibrium between β-sheet and partially helical structures. Biochemistry 1997, 36, 1233-1241.
-
(1997)
Biochemistry
, vol.36
, pp. 1233-1241
-
-
Melacini, G.1
Zhu, Q.2
Goodman, M.3
-
28
-
-
0027085885
-
Side chain chiral methylated somatostatin analog synthesis and conformational analysis
-
Huang, Z.; He, Y.; Raynor, K.; Tallent, M.; Reisine, T. et al. Side chain chiral methylated somatostatin analog synthesis and conformational analysis. J. Am. Chem. Soc. 1992, 114, 9390-9401.
-
(1992)
J. Am. Chem. Soc.
, vol.114
, pp. 9390-9401
-
-
Huang, Z.1
He, Y.2
Raynor, K.3
Tallent, M.4
Reisine, T.5
-
29
-
-
0030837553
-
A refined model for the somatostatin pharmacophore: Conformational analysis of lanthionine-sandostatin analogs
-
Melacini, G.; Zhu, Q.; Osapay, G.; Goodman, M. A refined model for the somatostatin pharmacophore: Conformational analysis of lanthionine-sandostatin analogs. J. Med. Chem. 1997, 40, 2252-2258.
-
(1997)
J. Med. Chem.
, vol.40
, pp. 2252-2258
-
-
Melacini, G.1
Zhu, Q.2
Osapay, G.3
Goodman, M.4
-
30
-
-
0032564880
-
Discovery of a novel non-peptide somatostatin agonist with SST4 selectivity
-
Ankersen, M.; Crider, M.; Liu, S.; Ho, B.; Andersen, H. S. et al. Discovery of a novel non-peptide somatostatin agonist with SST4 selectivity. J. Am. Chem. Soc. 1998, 120, 1368-1373.
-
(1998)
J. Am. Chem. Soc.
, vol.120
, pp. 1368-1373
-
-
Ankersen, M.1
Crider, M.2
Liu, S.3
Ho, B.4
Andersen, H.S.5
-
32
-
-
0032561511
-
Rapid identification of subtype-selective agonists of the somatostatin receptor through combinatorial chemistry
-
Rohrer, S. P.; Birzin, E. T.; Mosley, R. T.; Berk, S. C.; Hutchins, S. M. et al. Rapid identification of subtype-selective agonists of the somatostatin receptor through combinatorial chemistry. Science 1998, 282, 737-740.
-
(1998)
Science
, vol.282
, pp. 737-740
-
-
Rohrer, S.P.1
Birzin, E.T.2
Mosley, R.T.3
Berk, S.C.4
Hutchins, S.M.5
-
33
-
-
0038754828
-
Effects of heterocyclic aromatic substituents on binding affinities at two distinct sites of somatostatin receptors. Correlation with the electrostatic potential of the substituents
-
Prasad, V.; Birzin, E. T.; McVaugh, C. T.; Van Rijn, R. D.; Rohrer, S. P. et al. Effects of heterocyclic aromatic substituents on binding affinities at two distinct sites of somatostatin receptors. Correlation with the electrostatic potential of the substituents. J. Med. Chem. 2003, 46, 1858-1869.
-
(2003)
J. Med. Chem.
, vol.46
, pp. 1858-1869
-
-
Prasad, V.1
Birzin, E.T.2
McVaugh, C.T.3
Van Rijn, R.D.4
Rohrer, S.P.5
-
34
-
-
33845378943
-
1H NMR spectra via two-dimensional homonuclear Hartmann-Hahn spectroscopy
-
1H NMR spectra via two-dimensional homonuclear Hartmann-Hahn spectroscopy. J. Am. Chem. Soc. 1985, 107, 2820-2821.
-
(1985)
J. Am. Chem. Soc.
, vol.107
, pp. 2820-2821
-
-
Davis, D.G.1
Bax, A.2
-
35
-
-
0344448273
-
Coherence transfer by isotropic mixing: Application to proton correlation spectroscopy
-
Braunschweiler, L.; Ernst, R. R. Coherence transfer by isotropic mixing: Application to proton correlation spectroscopy. J. Magn. Reson. 1983, 53, 521-528.
-
(1983)
J. Magn. Reson.
, vol.53
, pp. 521-528
-
-
Braunschweiler, L.1
Ernst, R.R.2
-
36
-
-
0039457219
-
Improved spectral resolution in COSY1H NMR spectra of proteins via double quantum filtering
-
Ranee, M.; Sorensen, O. W.; Bodenhausen, B.; Wagner, G.; Ernst, R. R. et al. Improved spectral resolution in COSY1H NMR spectra of proteins via double quantum filtering. Biochem. Biophys. Res. Commun. 1983, 117, 479-485.
-
(1983)
Biochem. Biophys. Res. Commun.
, vol.117
, pp. 479-485
-
-
Ranee, M.1
Sorensen, O.W.2
Bodenhausen, B.3
Wagner, G.4
Ernst, R.R.5
-
37
-
-
12644267957
-
Buildup rates of the nuclear Overhauser effect measured by two-dimensional proton magnetic resonance spectroscopy: Implications for studies of protein conformation
-
Kumar, A.; Wagner, G.; Ernst, R. R.; Wüthrich, K. Buildup rates of the nuclear Overhauser effect measured by two-dimensional proton magnetic resonance spectroscopy: Implications for studies of protein conformation. J. Am. Chem. Soc. 1981, 103, 3654-3658.
-
(1981)
J. Am. Chem. Soc.
, vol.103
, pp. 3654-3658
-
-
Kumar, A.1
Wagner, G.2
Ernst, R.R.3
Wüthrich, K.4
-
38
-
-
84915716471
-
Elucidation of cross-relaxation in liquids by two-dimensional NMR spectroscopy
-
Macura, S.; Ernst, R. R. Elucidation of cross-relaxation in liquids by two-dimensional NMR spectroscopy. Mol. Phys. 1980, 41, 95-117.
-
(1980)
Mol. Phys.
, vol.41
, pp. 95-117
-
-
Macura, S.1
Ernst, R.R.2
-
39
-
-
49049150378
-
Two-dimensional chemical exchange and cross-relaxation spectroscopy of coupled nuclear spins
-
Macura, S.; Huang, Y.; Suter, D.; Ernst, R. R. Two-dimensional chemical exchange and cross-relaxation spectroscopy of coupled nuclear spins. J. Magn. Reson. 1981, 43, 259-281.
-
(1981)
J. Magn. Reson.
, vol.43
, pp. 259-281
-
-
Macura, S.1
Huang, Y.2
Suter, D.3
Ernst, R.R.4
-
40
-
-
0000088628
-
Processing of multidimensional NMR data with the new software PROSA
-
Güntert, P.; Dotsch, V.; Wider, G.; Wüthrich, K. Processing of multidimensional NMR data with the new software PROSA. J. Biolmol. NMR 1992, 2, 619-629.
-
(1992)
J. Biolmol. NMR
, vol.2
, pp. 619-629
-
-
Güntert, P.1
Dotsch, V.2
Wider, G.3
Wüthrich, K.4
-
41
-
-
0026193519
-
Efficient analysis of protein 2D NMR spectra using the software package EASY
-
Eccles, C.; Güntert, P.; Billeter, M.; Wüthrich, K. Efficient analysis of protein 2D NMR spectra using the software package EASY. J. Biomol. NMR 1991, 1, 111-130.
-
(1991)
J. Biomol. NMR
, vol.1
, pp. 111-130
-
-
Eccles, C.1
Güntert, P.2
Billeter, M.3
Wüthrich, K.4
-
43
-
-
0002692190
-
Biosym force field research results in new techniques for the extraction of inter- and intramolecular forces
-
Maple, J. R.; Thacher, T. S.; Dinur, U.; Hagler, A. T. Biosym force field research results in new techniques for the extraction of inter- and intramolecular forces. Chem. Design Auto. News 1990, 5, 5-10.
-
(1990)
Chem. Design Auto. News
, vol.5
, pp. 5-10
-
-
Maple, J.R.1
Thacher, T.S.2
Dinur, U.3
Hagler, A.T.4
-
44
-
-
0034624823
-
Consensus bioactive conformation of cyclic GnRH antagonists defined by NMR and molecular modeling
-
Koerber, S. C.; Rizo, J.; Struthers, R. S.; Rivier, J. E. Consensus bioactive conformation of cyclic GnRH antagonists defined by NMR and molecular modeling. J. Med. Chem. 2000, 43, 819-828.
-
(2000)
J. Med. Chem.
, vol.43
, pp. 819-828
-
-
Koerber, S.C.1
Rizo, J.2
Struthers, R.S.3
Rivier, J.E.4
-
45
-
-
0000551435
-
Theoretical simulation of conformation, energetics and dynamics of peptides
-
Academic Press: Orlando, FL
-
Hagler, A. T. Theoretical simulation of conformation, energetics and dynamics of peptides. The Peptides: Analysis, Synthesis, Biology; Academic Press: Orlando, FL, 1985; pp 213-299.
-
(1985)
The Peptides: Analysis, Synthesis, Biology
, pp. 213-299
-
-
Hagler, A.T.1
-
46
-
-
0038188032
-
MOLMOL: A program for display and analysis of macromolecular structures
-
Koradi, R.; Billeter, M. MOLMOL: a program for display and analysis of macromolecular structures. PDB Newsletter 1998, 84, 5-7.
-
(1998)
PDB Newsletter
, vol.84
, pp. 5-7
-
-
Koradi, R.1
Billeter, M.2
|