Enthalpic and entropic contributions mediate the role of disulfide bonds on the conformational stability of Interleukin-4

Protein Science

Volumn 15, Issue 1, 2006, Pages 33-44

  Vaz, Daniela C ^a   Rodrigues, J Rui ^a   Sebald, Walter ^b   Dobson, Christopher M ^c   Brito, Rui M M ^a,d  

^a UNIVERSITY OF COIMBRA   (Portugal)

^b UNIVERSITY OF WÜRZBURG   (Germany)

^c UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^d UNIVERSITY OF COIMBRA   (Portugal)

Author keywords

Conformational stability; Disulfide bridges; Enthalpy; Entropy; Four helix bundle; Interleukin 4; Thermal unfolding; Urea

Indexed keywords

DISULFIDE; INTERLEUKIN 4; MUTANT PROTEIN;

ARTICLE; CIRCULAR DICHROISM; CONFORMATIONAL TRANSITION; DISULFIDE BOND; ENTHALPY; ENTROPY; FLUORESCENCE ANALYSIS; MOLECULAR DYNAMICS; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN STABILITY; PROTEIN STRUCTURE; THERMODYNAMICS; THERMOSTABILITY; TRANSITION TEMPERATURE; WILD TYPE;

EID: 29344441722     PISSN: 09618368     EISSN: 1469896X     Source Type: Journal    
DOI: 10.1110/ps.051593306     Document Type: Article

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